Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
Journal Cover
October-2017 Volume 40 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
October-2017 Volume 40 Issue 4

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury

Retraction in: /10.3892/ijmm.2025.5549
  • Authors:
    • Bing Xiao
    • Yi Chai
    • Shigang Lv
    • Minhua Ye
    • Miaojing Wu
    • Liyuan Xie
    • Yanghua Fan
    • Xingen Zhu
    • Ziyun Gao
  • View Affiliations / Copyright

    Affiliations: Department of Neurosurgery, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, P.R. China
    Copyright: © Xiao et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1201-1209
    |
    Published online on: August 23, 2017
       https://doi.org/10.3892/ijmm.2017.3106
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Cerebral ischemia is a leading cause of death and disability. A previous study indicated that remote ischemic postconditioning (RIP) in the treatment of cerebral ischemia reduces ischemia/reperfusion (I/R) injury. However, the underlying mechanism is not well understood. In the present study, the authors hypothesized that the protective effect of RIP on neurological damage is mediated by exosomes that are released by endothelial cells in femoral arteries. To test this, right middle cerebral artery occlusion/reperfusion with RIP was performed in rats. In addition, an I/R injury cell model was tested that included human umbilical vein endothelial cells (HUVECs) and SH-SY5Y cells. Both the in vivo and in vitro models were examined for injury. Markers of exosomes (CD63, HSP70 and TSG101) were assessed by immunohistochemistry, western blot analysis and flow cytometry. Exosomes were extracted from both animal serum and HUVEC culture medium and identified by electron microscopy. They investigated the role of endothelial cell-derived exosomes in the proliferation, apoptosis, cell cycle, migration and invasion of I/R-injured SH-SY5Y cells. In addition, apoptosis-related molecules caspase-3, Bax and Bcl-2 were detected. RIP was determined to increase the number of exosomes and the expression levels of CD63, HSP70 and TSG101 in plasma, but not in brain hippocampal tissue. The size of exosomes released after I/R in HUVECs was similar to the size of exosomes released in rats subjected to RIP. Endothelial cell-derived exosomes partly suppressed the I/R-induced cell cycle arrest and apoptosis, and inhibited cell proliferation, migration and invasion in SH-SY5Y nerve cells. Endothelial cell-derived exosomes directly protect nerve cells against I/R injury, and are responsible for the protective role of RIP in I/R.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

View References

1 

Schreuder FH, Sato S, Klijn CJ and Anderson CS: Medical management of intracerebral haemorrhage. J Neurol Neurosurg Psychiatry. 88:76–84. 2017. View Article : Google Scholar

2 

Guerram M, Zhang LY and Jiang ZZ: G-protein coupled receptors as therapeutic targets for neurodegenerative and cerebrovascular diseases. Neurochem Int. 101:1–14. 2016. View Article : Google Scholar : PubMed/NCBI

3 

Guan WJ, Zheng XY, Chung KF and Zhong NS: Impact of air pollution on the burden of chronic respiratory diseases in China: Time for urgent action. Lancet. 388:1939–1951. 2016. View Article : Google Scholar : PubMed/NCBI

4 

Yang Y, Shi YZ, Zhang N, Wang S, Ungvari GS, Ng CH, Wang YL, Zhao XQ, Wang YJ, Wang CX, et al: The disability rate of 5-year post-stroke and its correlation factors: A national survey in China. PLoS One. 11:e01653412016. View Article : Google Scholar : PubMed/NCBI

5 

Zeng Y, Liu JX, Yan ZP, Yao XH and Liu XH: Potential microRNA biomarkers for acute ischemic stroke. Int J Mol Med. 36:1639–1647. 2015. View Article : Google Scholar : PubMed/NCBI

6 

Akpan N and Troy CM: Caspase inhibitors: Prospective therapies for stroke. Neuroscientist. 19:129–136. 2013. View Article : Google Scholar

7 

van Ierssel SH, Conraads VM, Van Craenenbroeck EM, Liu Y, Maas AI, Parizel PM, Hoymans VY, Vrints CJ and Jorens PG: Endothelial dysfunction in acute brain injury and the development of cerebral ischemia. J Neurosci Res. 93:866–872. 2015. View Article : Google Scholar : PubMed/NCBI

8 

Lavi S, Abu-Romeh N, Wall S, Alemayehu M and Lavi R: Long-term outcome following remote ischemic postconditioning during percutaneous coronary interventions-the RIP-PCI trial long-term follow-up. Clin Cardiol. 40:268–274. 2017. View Article : Google Scholar : PubMed/NCBI

9 

Fan YY, Hu WW, Nan F and Chen Z: Postconditioning-induced neuroprotection, mechanisms and applications in cerebral ischemia. Neurochem Int. 107:43–56. 2017. View Article : Google Scholar : PubMed/NCBI

10 

Andreadou I, Iliodromitis EK, Lazou A, Görbe A, Giricz Z, Schulz R and Ferdinandy P: Effect of hypercholesterolaemia on myocardial function, ischaemia-reperfusion injury and cardioprotection by preconditioning, postconditioning and remote conditioning. Br J Pharmacol. 174:1555–1569. 2017. View Article : Google Scholar : PubMed/NCBI

11 

Vyas N and Dhawan J: Exosomes: Mobile platforms for targeted and synergistic signaling across cell boundaries. Cell Mol Life Sci. 74:1567–1576. 2017. View Article : Google Scholar

12 

Holzner S, Senfter D, Stadler S, Staribacher A, Nguyen CH, Gaggl A, Geleff S, Huttary N, Krieger S, Jäger W, et al: Colorectal cancer cell-derived microRNA200 modulates the resistance of adjacent blood endothelial barriers in vitro. Oncol Rep. 36:3065–3071. 2016. View Article : Google Scholar : PubMed/NCBI

13 

Castelli G, Parolini I, Cerio AM, D'Angiò A, Pasquini L, Carollo M, Sargiacomo M, Testa U and Pelosi E: Conditioned medium from human umbilical vein endothelial cells markedly improves the proliferation and differentiation of circulating endothelial progenitors. Blood Cells Mol Dis. 61:58–65. 2016. View Article : Google Scholar : PubMed/NCBI

14 

Wei JJ, Chen YF, Xue CL, Ma BT, Shen YM, Guan J, Bao XJ, Wu H, Han Q, Wang RZ, et al: Protection of nerve injury with exosome extracted from mesenchymal stem cell. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 38:33–36. 2016.PubMed/NCBI

15 

Lozito TP and Tuan RS: Endothelial and cancer cells interact with mesenchymal stem cells via both microparticles and secreted factors. J Cell Mol Med. 18:2372–2384. 2014. View Article : Google Scholar : PubMed/NCBI

16 

Hofer HR and Tuan RS: Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies. Stem Cell Res Ther. 7:1312016. View Article : Google Scholar : PubMed/NCBI

17 

Teixeira FG, Panchalingam KM, Anjo SI, Manadas B, Pereira R, Sousa N, Salgado AJ and Behie LA: Do hypoxia/normoxia culturing conditions change the neuroregulatory profile of Wharton Jelly mesenchymal stem cell secretome? Stem Cell Res Ther. 6:1332015. View Article : Google Scholar : PubMed/NCBI

18 

Schey KL, Luther JM and Rose KL: Proteomics characterization of exosome cargo. Methods. 87:75–82. 2015. View Article : Google Scholar : PubMed/NCBI

19 

Chen X, Liu Y, Zhu J, Lei S, Dong Y, Li L, Jiang B, Tan L, Wu J, Yu S, et al: GSK-3β downregulates Nrf2 in cultured cortical neurons and in a rat model of cerebral ischemia-reperfusion. Sci Rep. 6:201962016. View Article : Google Scholar

20 

Shu S, Li CM, You YL, Qian XL, Zhou S and Ling CQ: Electroacupuncture ameliorates cerebral ischemia-Reperfusion injury by regulation of autophagy and apoptosis. Evid Based Complement Alternat Med. 2016:72974252016. View Article : Google Scholar : PubMed/NCBI

21 

Zeng Y and Liu J: Role of glypican-1 in endothelial NOS activation under various steady shear stress magnitudes. Exp Cell Res. 348:184–189. 2016. View Article : Google Scholar : PubMed/NCBI

22 

Marutani E, Yamada M, Ida T, Tokuda K, Ikeda K, Kai S, Shirozu K, Hayashida K, Kosugi S, Hanaoka K, et al: Thiosulfate mediates cytoprotective effects of hydrogen sulfide against neuronal ischemia. J Am Heart Assoc. 4:42015.

23 

Yan Z, Liu J, Xie L, Liu X and Zeng Y: Role of heparan sulfate in mediating CXCL8-induced endothelial cell migration. PeerJ. 4:e16692016. View Article : Google Scholar : PubMed/NCBI

24 

Zeng Y, Sun HR, Yu C, Lai Y, Liu XJ, Wu J, Chen HQ and Liu XH: CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration. Cytokine. 53:42–51. 2011. View Article : Google Scholar

25 

Zeng Y, Yao X, Chen L, Yan Z, Liu J, Zhang Y, Feng T, Wu J and Liu X: Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/syndecan-1/TGF-β autocrine loop. Oncotarget. 7:63324–63337. 2016. View Article : Google Scholar : PubMed/NCBI

26 

Gnosa S, Capodanno A, Murthy RV, Jensen LD and Sun XF: AEG-1 knockdown in colon cancer cell lines inhibits radiation-enhanced migration and invasion in vitro and in a novel in vivo zebrafish model. Oncotarget. 7:81634–81644. 2016.PubMed/NCBI

27 

Lapi D and Colantuoni A: Remodeling of cerebral microcirculation after ischemia-reperfusion. J Vasc Res. 52:22–31. 2015. View Article : Google Scholar : PubMed/NCBI

28 

Yu Q, Huang J, Hu J and Zhu H: Advance in spinal cord ischemia reperfusion injury: Blood-spinal cord barrier and remote ischemic preconditioning. Life Sci. 154:34–38. 2016. View Article : Google Scholar : PubMed/NCBI

29 

Randhawa PK and Jaggi AS: Unraveling the role of adenosine in remote ischemic preconditioning-induced cardioprotection. Life Sci. 155:140–146. 2016. View Article : Google Scholar : PubMed/NCBI

30 

Heusch G and Rassaf T: Time to give up on cardioprotection? A critical appraisal of clinical studies on ischemic pre-, post-, and remote conditioning. Circ Res. 119:676–695. 2016. View Article : Google Scholar : PubMed/NCBI

31 

Hoda MN, Bhatia K, Hafez SS, Johnson MH, Siddiqui S, Ergul A, Zaidi SK, Fagan SC and Hess DC: Remote ischemic perconditioning is effective after embolic stroke in ovariectomized female mice. Transl Stroke Res. 5:484–490. 2014. View Article : Google Scholar : PubMed/NCBI

32 

Limani P, Linecker M, Oberkofler CE, Barmettler G, Kaech A, Graf R, Humar B and Clavien PA: Remote ischemic preconditioning: A novel strategy in rescuing older livers from ischemia-reperfusion injury in a rodent model. Ann Surg. 264:797–803. 2016. View Article : Google Scholar : PubMed/NCBI

33 

Kadota T, Fujita Y, Yoshioka Y, Araya J, Kuwano K and Ochiya T: Extracellular vesicles in chronic obstructive pulmonary disease. Int J Mol Sci. 17:172016. View Article : Google Scholar

34 

Huang-Doran I, Zhang CY and Vidal-Puig A: Extracellular vesicles: Novel mediators of cell communication in metabolic disease. Trends Endocrinol Metab. 28:3–18. 2017. View Article : Google Scholar

35 

Nakajima A, Tsuji M, Inagaki M, Tamura Y, Kato M, Niiya A, Usui Y and Oguchi K: Neuroprotective effects of propofol on ER stress-mediated apoptosis in neuroblastoma SH-SY5Y cells. Eur J Pharmacol. 725:47–54. 2014. View Article : Google Scholar : PubMed/NCBI

36 

Lu J, Li YH, Zhan X, Li G, Chen Z and Chen X: The protective effect of qiancao naomaitong mixture on neuronal damage and cerebral ischemia/reperfusion injury. Pharm Biol. 54:2304–2311. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Xiao B, Chai Y, Lv S, Ye M, Wu M, Xie L, Fan Y, Zhu X and Gao Z: Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549. Int J Mol Med 40: 1201-1209, 2017.
APA
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L. ... Gao, Z. (2017). Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549. International Journal of Molecular Medicine, 40, 1201-1209. https://doi.org/10.3892/ijmm.2017.3106
MLA
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L., Fan, Y., Zhu, X., Gao, Z."Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549". International Journal of Molecular Medicine 40.4 (2017): 1201-1209.
Chicago
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L., Fan, Y., Zhu, X., Gao, Z."Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549". International Journal of Molecular Medicine 40, no. 4 (2017): 1201-1209. https://doi.org/10.3892/ijmm.2017.3106
Copy and paste a formatted citation
x
Spandidos Publications style
Xiao B, Chai Y, Lv S, Ye M, Wu M, Xie L, Fan Y, Zhu X and Gao Z: Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549. Int J Mol Med 40: 1201-1209, 2017.
APA
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L. ... Gao, Z. (2017). Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549. International Journal of Molecular Medicine, 40, 1201-1209. https://doi.org/10.3892/ijmm.2017.3106
MLA
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L., Fan, Y., Zhu, X., Gao, Z."Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549". International Journal of Molecular Medicine 40.4 (2017): 1201-1209.
Chicago
Xiao, B., Chai, Y., Lv, S., Ye, M., Wu, M., Xie, L., Fan, Y., Zhu, X., Gao, Z."Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549". International Journal of Molecular Medicine 40, no. 4 (2017): 1201-1209. https://doi.org/10.3892/ijmm.2017.3106
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team