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International Journal of Molecular Medicine
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Print ISSN: 1107-3756 Online ISSN: 1791-244X
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October-2017 Volume 40 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Review Open Access

Effect of diet and individual dietary guidance on gastrointestinal endocrine cells in patients with irritable bowel syndrome (Review)

Tarek Mazzawi, Magdy El-Salhy
Pages: 943-952
Published online on: 11 August 2017

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Review

Histone lysine methylation and congenital heart disease: From bench to bedside (Review)

Xin Yi, Xuejun Jiang, Xiaoyan Li, Ding-Sheng Jiang
Pages: 953-964
Published online on: 30 August 2017

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Review Open Access

Kidins220 and tumour development: Insights into a complexity of cross-talk among signalling pathways (Review)

Shuo Cai, Jun Cai, Wen G. Jiang, Lin Ye
Pages: 965-971
Published online on: 09 August 2017

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Review

Anti-angiogenic properties of artemisinin derivatives (Review)

Tianshu Wei, Ju Liu
Pages: 972-978
Published online on: 31 July 2017

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Article Open Access

Ubiquitin specific peptidase 4 stabilizes interferon regulatory factor protein and promotes its function to facilitate interleukin-4 expression in T helper type 2 cells

Zhixiang Guo, Peng Xu, Shangqing Ge, Chengxin Zhang, Xiaoyan Zheng, Jinguo Xu, Zhuang Liu, Bin Li, Shenglin Ge
Pages: 979-986
Published online on: 03 August 2017

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Article Open Access

Advanced glycation end products decrease collagen I levels in fibroblasts from the vaginal wall of patients with POP via the RAGE, MAPK and NF-κB pathways

Yi-Song Chen, Xiao-Juan Wang, Weiwei Feng, Ke-Qin Hua
Pages: 987-998
Published online on: 11 August 2017

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Article Open Access

Trichostatin A attenuates oxidative stress-mediated myocardial injury through the FoxO3a signaling pathway

Yunhui Guo, Zhiping Li, Canxia Shi, Jia Li, Meng Yao, Xia Chen
Pages: 999-1008
Published online on: 17 August 2017

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Article Open Access

The ROCK inhibitor, thiazovivin, inhibits human corneal endothelial‑to‑mesenchymal transition/epithelial‑to‑mesenchymal transition and increases ionic transporter expression

Qianni Wu, Chen Ouyang, Lijie Xie, Yunzhi Ling, Ting Huang
Pages: 1009-1018
Published online on: 18 August 2017

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Article Open Access

Integrating microRNA and messenger RNA expression profiles in a rat model of deep vein thrombosis

Qian-Qian Jin, Jun-Hong Sun, Qiu-Xiang Du, Xiao-Jun Lu, Xi-Yan Zhu, Hao-Liang Fan, Christian Hölscher, Ying-Yuan Wang
Pages: 1019-1028
Published online on: 23 August 2017

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Article Open Access

Particulate matter 2.5 regulates lipid synthesis and inflammatory cytokine production in human SZ95 sebocytes

Qin Liu, Jianbo Wu, Jiquan Song, Pin Liang, Kaiping Zheng, Guifeng Xiao, Lanting Liu, Christos C. Zouboulis, Tiechi Lei
Pages: 1029-1036
Published online on: 25 August 2017

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Article Open Access

Functional roles of C/EBPα and SUMO‑modification in lung development

Yuan-Dong Chen, Jiang-Yan Liu, Yan-Min Lu, Hai-Tao Zhu, Wei Tang, Qiu-Xia Wang, Hong-Yan Lu
Pages: 1037-1046
Published online on: 29 August 2017

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Article Open Access

miR-378 functions as an onco-miRNA by targeting the ST7L/Wnt/β-catenin pathway in cervical cancer

Shengjie Li, Fengxia Yang, Meiyan Wang, Wenjun Cao, Zhen Yang
Pages: 1047-1056
Published online on: 30 August 2017

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Article Open Access

Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts

Shingo Kainuma, Haruhiko Tokuda, Naohiro Yamamoto, Gen Kuroyanagi, Kazuhiko Fujita, Tetsu Kawabata, Go Sakai, Rie Matsushima-Nishiwaki, Osamu Kozawa, Takanobu Otsuka
Pages: 1057-1066
Published online on: 01 September 2017

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Article Open Access

Breast cancer-associated gene 3 interacts with Rac1 and augments NF-κB signaling in vitro, but has no effect on RANKL-induced bone resorption in vivo

Chen Yao, Kuan-Ping Yu, William Philbrick, Ben-Hua Sun, Christine Simpson, Changqing Zhang, Karl Insogna
Pages: 1067-1077
Published online on: 04 August 2017

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Article Open Access

Mass spectrometric identification of dystrophin, the protein product of the Duchenne muscular dystrophy gene, in distinct muscle surface membranes

Sandra Murphy, Kay Ohlendieck
Pages: 1078-1088
Published online on: 27 July 2017

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Article Open Access

Grifola frondosa polysaccharides induce breast cancer cell apoptosis via the mitochondrial-dependent apoptotic pathway Corrigendum in /10.3892/ijmm.2022.5192

Yizhi Zhang, Dejun Sun, Qingjin Meng, Wanxu Guo, Qiuhui Chen, Ying Zhang
Pages: 1089-1095
Published online on: 26 July 2017

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Article Open Access

Classification of cancer cell lines using matrix-assisted laser desorption/ionization time‑of‑flight mass spectrometry and statistical analysis

Vlad Serafim, Ajit Shah, Maria Puiu, Nicoleta Andreescu, Dorina Coricovac, Alexander Nosyrev, Demetrios A. Spandidos, Aristides M. Tsatsakis, Cristina Dehelean, Iulia Pinzaru
Pages: 1096-1104
Published online on: 27 July 2017

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Article Open Access

Identification of differentially expressed microRNAs in knee anterior cruciate ligament tissues surgically removed from patients with osteoarthritis

Bin Li, Lunhao Bai, Peng Shen, Yue Sun, Zhizuo Chen, Yu Wen
Pages: 1105-1113
Published online on: 31 July 2017

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Article Open Access

Suppression of CUL4A attenuates TGF-β1-induced epithelial-to-mesenchymal transition in breast cancer cells Retraction in /10.3892/ijmm.2023.5224

Yunshan Wang, Xiaoyan Liu, Hui Zheng, Qin Wang, Li An, Guangwei Wei
Pages: 1114-1124
Published online on: 01 September 2017

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Article Open Access

Nova1 mediates resistance of rat pheochromocytoma cells to hypoxia-induced apoptosis via the Bax/Bcl-2/caspase-3 pathway

Hualing Li, Bei Lv, Ling Kong, Jing Xia, Ming Zhu, Lijuan Hu, Danyang Zhen, Yifan Wu, Xiaoqin Jia, Sujuan Zhu, Hengmi Cui
Pages: 1125-1133
Published online on: 03 August 2017

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Article Open Access

Ginsenoside Rg1 protects against neuronal degeneration induced by chronic dexamethasone treatment by inhibiting NLRP-1 inflammasomes in mice

Yaodong Zhang, Wen Hu, Biqiong Zhang, Yanyan Yin, Junyan Zhang, Dake Huang, Rongrong Huang, Weiping Li, Weizu Li
Pages: 1134-1142
Published online on: 09 August 2017

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Article Open Access

Osthole induces apoptosis and suppresses proliferation via the PI3K/Akt pathway in intrahepatic cholangiocarcinoma

Xingyang Zhu, Xiaoling Song, Kun Xie, Xue Zhang, Wei He, Fubao Liu
Pages: 1143-1151
Published online on: 30 August 2017

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Article Open Access

Identification of CALM as the potential serum biomarker for predicting the recurrence of nasopharyngeal carcinoma using a mass spectrometry-based comparative proteomic approach

Huiling Meng, Xiaodong Zhu, Ling Li, Zhongguo Liang, Xiaoyu Li, Xinbin Pan, Fanyan Zeng, Song Qu
Pages: 1152-1164
Published online on: 09 August 2017

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Article Open Access

Suppression of CIP4/Par6 attenuates TGF-β1-induced epithelial-mesenchymal transition in NRK-52E cells

Ying-Chun Zhu, Ya-Kun Wang, Shou-Jun Bai, Fang-Fang Zha, Gang Feng, Cong-Pu Gao, Juan Liu
Pages: 1165-1171
Published online on: 16 August 2017

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Article Open Access

Regulated differentiation of WERI-Rb-1 cells into retinal neuron-like cells

Ying Liu, Huiling Hu, Meixin Liang, Yunfan Xiong, Kang Li, Mengfei Chen, Zhigang Fan, Xielan Kuang, Fei Deng, Xiaohong Liu, Chaochao Xu, Kaijing Li, Jian Ge
Pages: 1172-1184
Published online on: 17 August 2017

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Article Open Access

Advanced glycation end products induce the apoptosis of and inflammation in mouse podocytes through CXCL9-mediated JAK2/STAT3 pathway activation

Jing Yu, Hao Wu, Zi-Yu Liu, Qi Zhu, Chang Shan, Ke-Qin Zhang
Pages: 1185-1193
Published online on: 11 August 2017

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Article Open Access

Panax ginseng extract antagonizes the effect of DKK‑1-induced catagen-like changes of hair follicles

Yonghee Lee, Su Na Kim, Yong Deog Hong, Byung Cheol Park, Yongjoo Na
Pages: 1194-1200
Published online on: 25 August 2017

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Article Open Access

Endothelial cell-derived exosomes protect SH-SY5Y nerve cells against ischemia/reperfusion injury Retraction in /10.3892/ijmm.2025.5549

Bing Xiao, Yi Chai, Shigang Lv, Minhua Ye, Miaojing Wu, Liyuan Xie, Yanghua Fan, Xingen Zhu, Ziyun Gao
Pages: 1201-1209
Published online on: 23 August 2017

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Article Open Access

Fluid shear stress regulates vascular remodeling via VEGFR-3 activation, although independently of its ligand, VEGF-C, in the uterus during pregnancy

Yang-Gyu Park, Jawun Choi, Hye-Kang Jung, In Kyu Song, Yongwhan Shin, Sang-Youel Park, Jae-Won Seol
Pages: 1210-1216
Published online on: 25 August 2017

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Article Open Access

EWS-FLI1 positively regulates autophagy by increasing ATG4B expression in Ewing sarcoma cells

Qunshan Lu, Yuankai Zhang, Liang Ma, Deqiang Li, Ming Li, Jianmin Li, Peilai Liu
Pages: 1217-1225
Published online on: 29 August 2017

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Article

MicroRNA-124 inhibits the proliferation of C6 glioma cells by targeting Smad4

Zechuan Zhang, Qiaoyun Gong, Meiying Li, Jinying Xu, Yangyang Zheng, Pengfei Ge, Guangfan Chi
Pages: 1226-1234
Published online on: 03 August 2017

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Article

miR-30a inhibits the biological function of breast cancer cells by targeting Notch1

He-Da Zhang, Lin-Hong Jiang, Da-Wei Sun, Jian Li, Jin-Hai Tang
Pages: 1235-1242
Published online on: 31 July 2017

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Article

Triticum aestivum sprout-derived polysaccharide exerts hepatoprotective effects against ethanol-induced liver damage by enhancing the antioxidant system in mice

Sarmila Nepali, Hyeon-Hui Ki, Ji-Hyun Lee, Ji-Yun Cha, Young-Mi Lee, Dae-Ki Kim
Pages: 1243-1252
Published online on: 11 August 2017

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Article

Insulin-like growth factor-1 promotes the proliferation and odontoblastic differentiation of human dental pulp cells under high glucose conditions

Lu Yan, Shangmin Sun, Liu Qu
Pages: 1253-1260
Published online on: 01 September 2017

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Article Open Access

Role of interferon regulatory factor-1 in lipopolysaccharide-induced mitochondrial damage and oxidative stress responses in macrophages

Song-Yun Deng, Le-Meng Zhang, Yu-Hang Ai, Pin-Hua Pan, Shuang-Ping Zhao, Xiao-Li Su, Dong-Dong Wu, Hong-Yi Tan, Li-Na Zhang, Allan Tsung
Pages: 1261-1269
Published online on: 25 August 2017

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Article

Isoastragaloside I inhibits NF-κB activation and inflammatory responses in BV-2 microglial cells stimulated with lipopolysaccharide

Hongshuai Liu, Fei Huang, Hui Wu, Beibei Zhang, Hailian Shi, Xiaojun Wu, Zhibi Hu
Pages: 1270-1276
Published online on: 30 August 2017

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Article

Melanogenesis in uveal melanoma cells: Effect of argan oil Corrigendum in /10.3892/ijmm.2023.5308

Nunzia Caporarello, Melania Olivieri, Martina Cristaldi, Dario Rusciano, Gabriella Lupo, Carmelina Daniela Anfuso
Pages: 1277-1284
Published online on: 23 August 2017

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Article

Antimicrobial activity and synergism of ursolic acid 3-O-α-L-arabinopyranoside with oxacillin against methicillin-resistant Staphylococcus aureus

Tian Zhou, Zhi Li, Ok‑Hwa Kang, Su‑Hyun Mun, Yun‑Soo Seo, Ryong Kong, Dong-Won Shin, Xiang‑Qian Liu, Dong‑Yeul Kwon
Pages: 1285-1293
Published online on: 14 August 2017

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Article

Apocynin protects mesangial cells from lipopolysaccharide-induced inflammation by exerting heme oxygenase 1-mediated monocyte chemoattractant protein-1 suppression

Nirmal Prasad Bhatt, Jin-Young Park, Hee Jae Lee, Sung-Soo Kim, Yong-Soo Kwon, Wanjoo Chun
Pages: 1294-1301
Published online on: 04 August 2017

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Journal Cover
June-2026 Volume 57 Issue 6

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article

Gilteritinib overcomes second‑generation TKIs resistance in ALK‑rearranged non‑small‑cell lung cancer by inhibiting PD‑L1 and CD8 co‑expression

Hang Guo, Yaoji Li, Chengyan Jin, Xiao Qi, Jincheng Wang, Baofeng Li, Chunguang Wang
Article Number: 168
Published online on: 28 April 2026

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Retraction Open Access

[Retracted] Metformin‑induced activation of AMPK inhibits the proliferation and migration of human aortic smooth muscle cells through upregulation of p53 and IFI16

Biao Hao, Yan Xiao, Fang Song, Xiangshu Long, Jing Huang, Maobo Tian, Shiyan Deng, Qiang Wu
Article Number: 167
Published online on: 22 April 2026

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Review Open Access

Dysregulation of the DNA repair‑immune axis: Targeted therapeutic strategies for autoimmune diseases (Review)

Ke Wan, Miao Wang, Qingqing Xia, Hui Fang, Ying Chen, Tongsheng Zhou, Xue Yang, Lu Wang, Jianwen Ye, Han Shu, Xiao-Feng Li, Jun Li
Article Number: 166
Published online on: 22 April 2026

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Retraction Open Access

[Retracted] Puerarin attenuates glucocorticoid‑induced apoptosis of hFOB1.19 cells through the JNK‑ and Akt‑mediated mitochondrial apoptotic pathways

Dongdong Yu, Shuai Mu, Danyang Zhao, Guangbin Wang, Zhiguang Chen, Hongfei Ren, Qin Fu
Article Number: 165
Published online on: 20 April 2026

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Review Open Access

High‑altitude polycythemia: Unveiling the molecular landscape beyond erythropoietin (Review)

Haiyan Li, Hongjuan Zhang, Hujun Zhang, Yujie Li, Yigang He, Jia Luan
Article Number: 164
Published online on: 17 April 2026

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Review

Mechanistic roles of interleukin‑18 in colonic immunity across infection, inflammatory bowel disease, and colorectal cancer (Review)

Jingwen Zhang, Lili Bao, Xia Li, Jiaxi Li, Jiaxian Cui, Lu Qiao, Xiaoxia He, Mingyu Zhang, Jingkun Lu, Xuan Zhang, Jing Dong, Gesi Tao, Tuya Bai, Yun Peng Tian, Pengwei Zhao, Ya Tuo
Article Number: 163
Published online on: 17 April 2026

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Article Open Access

IDH2 lactylation regulates mitochondrial dysfunction injury induced by myocardial ischemia‑reperfusion via the AMPK signaling pathway

Changsen Wang, Siman Shen, Suyun Chen, Jinda Lin, Simeng Li, Jianning Chen, Shuyun Cai, Xiaodong Yuan, Ziqiang Yang, Kun Ding, Li Xu, Liangqing Zhang
Article Number: 162
Published online on: 17 April 2026

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Review Open Access

Context‑dependent duality of the apelin/elabela‑APJ system in diabetes and its complications (Review)

Zhenyuan Han, Jiale Zhang, Min Shi, Juan Chen, Anni Li, Yuxuan Ye, Hong Zhang
Article Number: 161
Published online on: 17 April 2026

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Review Open Access

Glycolytic lactylation modulates cell death decisions in diabetic kidney disease: Metabolic‑epigenetic interplay between ferroptosis and autophagy in fibrotic remodeling (Review)

Taimin Zhang, Xizhe Zhang, Yaru Xie, Yue Liu, Siyu Xia, Xiaodie Yin, Tian Li, Libin Liao
Article Number: 160
Published online on: 16 April 2026

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Retraction Open Access

[Retracted] Quercetin promotes the apoptosis of fibroblast‑like synoviocytes in rheumatoid arthritis by upregulating lncRNA MALAT1

Fang Pan, Lihua Zhu, Haozhe Lv, Chunpeng Pei
Article Number: 159
Published online on: 15 April 2026

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Article Open Access

Triptolide exerts antiviral effects and alleviates influenza A‑induced pneumonia by inhibiting the overactivation of absent in melanoma 2 signaling in immune cells

Yeyang Chen, Hua Wu, Xiangjian Wu, Likun Che, Xiaoyan Fu, Ruihan Qi, Dan Jia, Minfang Li, Wei Xie, Wenxiang Zhu
Article Number: 158
Published online on: 15 April 2026

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Review Open Access

ETS‑1/ETS‑2 transcription factors in CVD (Review)

Shasha Yang, Jing Zhang, Ying Yang, Yunbo Lv, Jian Yang, Huibo Wang
Article Number: 157
Published online on: 15 April 2026

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Review Open Access

RNA‑binding proteins as epithelial transcriptome orchestrators in gastric cancer: Immune‑metabolic crosstalk and therapeutic vulnerability (Review)

Shuhui Liu, Zhiyuan Ma, Bei Ji, Jiaxing Zhu, Shun Yao, Shuji Terai, Biguang Tuo, Taolang Li, Xuemei Liu
Article Number: 156
Published online on: 14 April 2026

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Retraction Open Access

[Retracted] Role of miR‑146a in human chondrocyte apoptosis in response to mechanical pressure injury in vitro  

Lei Jin, Jian Zhao, Wensen Jing, Shiju Yan, Xin Wang, Chun Xiao, Baoan Ma
Article Number: 155
Published online on: 07 April 2026

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Review Open Access

A tale of dual role: HECT‑type E3 ubiquitin ligase mechanisms in liver diseases (Review)

Tongxi Li, Hao Chen, Peng Zhao, Chuanzheng Yin, Zifang Song
Article Number: 154
Published online on: 07 April 2026

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Correction Open Access

[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4 

Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen
Article Number: 153
Published online on: 03 April 2026

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Review Open Access

Macrophage metabolism reprogramming in sepsis: Pathogenesis and therapeutic implications (Review)

Tong Zhao, Wenzhe Zhang, Zixuan Ren, Xiujing Feng
Article Number: 152
Published online on: 03 April 2026

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Article Open Access

Astragaloside IV targets TUBB4B to inhibit proliferation and promote apoptosis of pituitary tumor cells via the STMN1/ERK pathway

Jiale Li, Yufei Qu, Wenge Zhang, Zexu Yang, Yangdong Zeng, Jisheng Xu, Kuncen Xie, Qi Liu
Article Number: 151
Published online on: 01 April 2026

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Expression of Concern Open Access

[Expression of Concern] Increased expression of heat shock protein 90 under chemical hypoxic conditions protects cardiomyocytes against injury induced by serum and glucose deprivation

Keng Wu, Wenming Xu, Qiong You, Runmin Guo, Jianqiang Feng, Changran Zhang, Wen Wu
Article Number: 150
Published online on: 01 April 2026

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Review Open Access

Animal models accurately representing acute liver failure (Review)

Sang Luo, Fang Wu, Yiran Jin, Xiaofen Huang, Dan Liu, Bingren Tian
Article Number: 149
Published online on: 01 April 2026

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Correction Open Access

[Corrigendum] Influence of aspirin on the CX3CL1/CX3CR1 signaling pathway in acute pulmonary embolism 

Zhirong Zhang, Weiji Yang, Rongbiao Ying, Ying Shi, Huifang Jiang, Danli Cai, Jing Kuang, Ruhui Yang, Lingcong Wang
Article Number: 148
Published online on: 31 March 2026

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Review Open Access

Targeting pyroptosis to treat aortic aneurysms: From mechanism to drug discovery (Review)

Jing Mao, Mandi Luo, Lei Ruan, Cuntai Zhang
Article Number: 147
Published online on: 31 March 2026

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Review Open Access

Role of aging‑related cytokines in neurodegenerative disease (Review)

Xinke Dai, Xinran Rao, Yuandi Wang, Weijiang Zhao
Article Number: 146
Published online on: 31 March 2026

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Expression of Concern Open Access

[Expression of Concern] DTX3L is upregulated in glioma and is associated with glioma progression

Peng Xu, Xuelei Tao, Chengjin Zhao, Qingfeng Huang, Hao Chang, Na Ban, Yuanqi Bei, Xiaojie Xia, Chaoyan Shen, Kun Wang, Li Xu, Peizhang Wu, Jianbing Ren, Donglin Wang
Article Number: 145
Published online on: 30 March 2026

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Review Open Access

Role of itaconate in intestinal disease (Review)

Xin Li, Qian Liu, Jiajia Li, Li Zhang, Shun Yao, Lulu Tang, Bingqi Yang, Yongfeng Wang, Guorong Wen, Jiaxing An, Hai Jin, Biguang Tuo
Article Number: 144
Published online on: 27 March 2026

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Unveiling lactylation: A novel frontier in the pathogenesis of diabetic nephropathy (Review)

Yuanyuan Xiao, Niansong Wang, Dingkun Gui, Youhua Xu
Article Number: 143
Published online on: 27 March 2026

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Review Open Access

Crosstalk between autophagy and ferroptosis in liver diseases (Review)

Yanming Wei, Kun Zhou, Yuerui Su, Zhihua Luan, Pengcheng Li, Yinxia Chang, Bo Han, Huifang Li, Yuanbiao Qiao, Jinhong Ren
Article Number: 142
Published online on: 26 March 2026

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Article Open Access

circOMA1 delivered by exosomes regulates DRD2‑mediated prolactinoma resistance

Qing Rao, Dimin Zhu, Zongming Wang, Shaolin Zhang, Xueli Li, Shashikiran Tagilapalli, Nan Wang, Weiyu Hu, Wenli Chen, Yonghong Zhu
Article Number: 141
Published online on: 26 March 2026

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Expression of Concern Open Access

[Expression of Concern] Involvement of Cyr61 in the growth, invasiveness and adhesion of esophageal squamous cell carcinoma cells

Jian-Jun Xie, Li-Yan Xu, Yang-Min Xie, Ze-Peng Du, Cai-Hua Feng, Hui Dong, En-Min Li
Article Number: 140
Published online on: 24 March 2026

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Article Open Access

Novel Hsp90 inhibitor JD‑02 inhibits HSV‑1 infection via the Raf/MEK/ERK signaling pathway

Yexuan Zhu, Xiaohui Wang, Jiaying Lin, Xiao Wang, Kai Zheng, Zhe Ren, Ji Xiao, Yifei Wang
Article Number: 139
Published online on: 24 March 2026

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July-2026 Volume 58 Issue 1

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Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Identification of diagnostic markers for diabetic kidney disease by weighted gene co‑expression network analysis and machine learning

Qiming Xu, Chunjing Xu, Ziyang Liu, Jianrao Lu, Jing Hu, Lin Liao
Article Number: 198
Published online on: 21 May 2026

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CTRP3 alleviates neuropathic pain by improving mitochondrial biogenesis and mitochondrial unfolded protein response via spinal SIRT1 in rats

Tianzhu Liu, Longqing Zhang, Wei Mei
Article Number: 197
Published online on: 21 May 2026

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[Corrigendum] Activated Wnt signaling induces myofibroblast differentiation of mesenchymal stem cells, contributing to pulmonary fibrosis

Zhaorui Sun, Cong Wang, Chaowen Shi, Fangfang Sun, Xiaomeng Xu, Weiping Qian, Shinan Nie, Xiaodong Han
Article Number: 196
Published online on: 20 May 2026

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Ganoderma lucidum polysaccharides improve liver metabolic disorders by modulating gut microbiota of ovariectomized mice

Xin Jin, Xuan Liu, Yun-Juan Wang, Zi-Li Lei, Yan-Hong Yang
Article Number: 195
Published online on: 20 May 2026

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Endothelial NOX4‑driven oxidative stress inhibition reverses HtrA1 deficiency‑induced blood‑brain barrier disruption and cognitive impairment

Shi-Na Song, Jun-Ying Wu, Mao-Mei Song, Xiao-Feng Li, Jian-Ming Wang, Wen-Hui Jia, Chang-Xin Li, Sui-Yi Xu
Article Number: 194
Published online on: 19 May 2026

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Bone‑origin repair in diabetic foot ulcers: Mechanisms of callus formation and endocrine effects in healing (Review)

Sen Chen, Xiaofei Cui
Article Number: 193
Published online on: 19 May 2026

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Review Open Access

Unraveling the molecular landscape of chronic radiation injury: From oxidative stress signaling to translational modeling (Review)

Zhenjun Xi, Xiaodong Li, Chunhui Yang, Li Wang, Jingxin Mao, Qianqian Liu, Chang Liu, Qian Li, Yuanfang Hou, Jie Wan, Chengzhuo Yang, Feiji Sun, Chao Yu, Miao Wang, Baocheng Yuan, Yongsheng Liu, Qing Hu, Li Zhang, Xuemei Li, Xiaobing Li
Article Number: 192
Published online on: 19 May 2026

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Retraction Open Access

[Retracted] Cocktail therapy with a combination of interferon, ribavirin and angiotensin‑II type 1 receptor blocker attenuates murine liver fibrosis development

Hitoshi Yoshiji, Ryuichi Noguchi, Yasuhide Ikenaka, Kosuke Kaji, Yosuke Aihara, Yusaku Shirai, Junichi Yoshii, Koji Yanase, Hiroshi Fukui
Article Number: 191
Published online on: 18 May 2026

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Autophagy and metabolic homeostasis: Exploration in obesity‑related metabolic diseases (Review)

Chenglin Lu, Xiangyu Qi, Yuting Tong, Peng Lu, Dandan Luo, Qingbo Guan, Chunxiao Yu
Article Number: 190
Published online on: 14 May 2026

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Primary cilia dysfunction: A critical driver of metabolic diseases (Review)

Xiaojing Wang, Yi Jin, Kejia Xie, Pengfei Yao, Liguo Song, Hongdan Liu, Yanjie Tan
Article Number: 189
Published online on: 14 May 2026

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Gut‑brain axis in anesthesia and critical illness: Molecular crosstalk and its impact on delirium and outcome (Review)

Xigang Ma, Yongsen Zhao
Article Number: 188
Published online on: 14 May 2026

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Article Open Access

Betulinic acid alleviates the inflammatory injury of osteoblasts in osteoporosis by augmenting autophagy via the AMPK-mTOR signaling pathway

Yiwei Zhao, Zechao Qu, Lin Liu, Yong Zhang, Xiaohao Wang, Bo Zhang, Yining Gong, Liang Yan
Article Number: 187
Published online on: 13 May 2026

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Correction Open Access

[Corrigendum] Induction of cardiomyocyte‑like cells from hair follicle cells in mice

Yong-Hee Kim, Bang-Jin Kim, Seok-Man Kim, Sun-Uk Kim, Buom-Yong Ryu
Article Number: 186
Published online on: 13 May 2026

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Review Open Access

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review)

Guiqing Chen, Hongyan Jia, Kai Zhao, Chang Gao, Yue Liu, Hong Zhu, Dakai Yang, Yun Cai
Article Number: 185
Published online on: 13 May 2026

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Article Open Access

Hepatic p38γ exacerbates acetaminophen‑induced acute liver injury via PI3K/Akt‑dependent mechanisms

Hui Fang, Min Shu, Jiaju Wang, Heng Tian, Jianguo Zhang, Ying Hu, He Li, Huan Zhou, Kangsheng Gu, Zhenhua Ren
Article Number: 184
Published online on: 12 May 2026

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Pharmacological activity, molecular mechanisms and therapeutic potential of erianin (Review)

Chengyi Ming, Ni Zhu, You Yu, Hong Zhou, Meichun Hu
Article Number: 183
Published online on: 12 May 2026

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Review Open Access

Rab27: Molecular switch of tumor exosome secretion (Review)

Mengtian Tang, Zhongjian Zhu, Huaxin Duan, Shiming Tan, Mengzhou Shen, Xianjie Jiang, Qiu Peng, Linda Oyang, Zongyao Ren, Yujuan Zhou, Qianjin Liao
Article Number: 182
Published online on: 12 May 2026

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Article Open Access

IL‑17A+ γδT cell activation via the HMGB1‑TLR2/4‑NF‑κB signaling pathways in biliary atresia

Meng-Xin Zhang, Jing-Feng Tang, Mei Hong, Ying Yang, Yun Zhou, Shui-Qing Chi, Li-Ying Rong, Guo-Qing Cao, Xi Zhang, Jin-Xiang Zhang, Shao-Tao Tang
Article Number: 181
Published online on: 11 May 2026

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Article Open Access

CircRAD18 promotes glioblastoma proliferation, migration and invasion via the miR‑1231/LUC7L2 axis

Lumeng Song, Ping Xiong, Amu Jike, Xiaochao Xia, Lifang Mao, Zihao Wang, Yinchuan Cheng, Shumin Wang, Shizheng Tan, Dongnan Yu, Zheng Li, Xiaoping Tang, Shun Li
Article Number: 180
Published online on: 11 May 2026

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Correction Open Access

[Corrigendum] Expression of FKBP52 in the ovaries of PCOS rats

Shiyan Song, Yong Tan
Article Number: 179
Published online on: 11 May 2026

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Article Open Access

miR‑223‑3p promotes microglial lactylation and M1 polarization via the FBXW7/Notch1/Hes1/SIRT1 axis

Xiaoyu Wang, Lin Song, Jiafeng Wang, Qianqian Xie, Yan Wang, Chunyan Li, Tianqi Wang, Yifeng Du
Article Number: 178
Published online on: 08 May 2026

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Review Open Access

Radiotherapy and cytokines: A systems view of immunotherapy and toxicity (Review)

Siyuan Zhou, Yurong Jiang, Jixu Fan, Minjie Guo, Yi Wen, Chunhua Dai
Article Number: 177
Published online on: 08 May 2026

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Review Open Access

Advances in understanding the NLRP3 inflammasome‑mediated mechanisms and therapeutic targets in diabetic nephropathy (Review)

Xiwei Wang, Shuang Li, Xiaotian Ge, Tao Xie, Sainan Li, Ruiqi Yuan, Tianxi Li, Hui Yuan
Article Number: 176
Published online on: 06 May 2026

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Expression of Concern Open Access

[Expression of Concern] ISL1 promotes cancer progression and inhibits cisplatin sensitivity in triple‑negative breast cancer cells

Yang Zhang, Lu Wang, Peng Gao, Zhiguo Sun, Ning Li, Yanqin Lu, Jianglun Shen, Jian Sun, Yiming Yang, Hao Dai, Haifeng Cai
Article Number: 175
Published online on: 06 May 2026

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Review Open Access

Phosphorylation beyond the plasma membrane: How secretory pathway kinases sculpt the cellular dialogue in cancer (Review)

Ziang Geng, Shu Guan, Shaoqi Du, Shuo Zhang, Jiaxin Hao, Siyuan Tian, Chen Zhu, Shaonan Du
Article Number: 174
Published online on: 06 May 2026

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Review Open Access

Ferroptosis in musculoskeletal disorders: Emerging mechanisms and therapeutic opportunities (Review)

Wenhui Gu, Haifeng Zhang, Lisha Ye, Fangming Liu, Ting Xu, Yinxian Yu, Guohua Wang
Article Number: 173
Published online on: 05 May 2026

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Retraction Open Access

[Retracted] Regulation of p38 MAPK phosphorylation inhibits chondrocyte apoptosis in response to heat stress or mechanical stress

Ken Takebe, Takayuki Nishiyama, Shinya Hayashi, Shingo Hashimoto, Takaaki Fujishiro, Noriyuki Kanzaki, Kohei Kawakita, Kenjiro Iwasa, Ryosuke Kuroda, Masahiro Kurosaka
Article Number: 172
Published online on: 04 May 2026

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Article Open Access

Dapagliflozin attenuates ferroptosis in diabetic nephropathy through activation of the Nrf2/HO‑1 signaling pathway

Hanshuang Liu, Xiaoxiao Zhang, Yubing Cui, Shengxi Xiong, Linjuan Huang, Min Li, Chen Shao, Xiaolei Hu
Article Number: 171
Published online on: 30 April 2026

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Article Open Access

Ligustroflavone protects against acute kidney injury by inhibiting ferroptosis via acting on GSK3β/NRF2 signaling

Jiayu Song, Long Wang, Yaru Wang, Jie Meng, Jingyi Sheng, Yongfeng Zhao, San Yan Xu, Juan Lei, Fangfang Cai, Yunwen Yang
Article Number: 170
Published online on: 30 April 2026

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Correction Open Access

[Corrigendum] Differential regulation of the biosynthesis of glucose transporters by the PI3‑K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla

Yoen Kyung Lee, Ji Eun Kim, So Hee Nam, Jun Seo Goo, Sun Il Cho, Young Hwan Choi, Chang Jun Bae, Ong Min Woo, Jung Sik Cho, Dae Youn Hwang
Article Number: 169
Published online on: 28 April 2026

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