|
1
|
Ozgocmen S, Kaya H, Fadillioglu E and
Yilmaz Z: Effects of calcitonin, risedronate, and raloxifene on
erythrocyte antioxidant enzyme activity, lipid peroxidation, and
nitric oxide in postmenopausal osteoporosis. Arch Med Res.
38:196–205. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ershler WB, Harman SM and Keller ET:
Immunologic aspects of osteoporosis. Dev Comp Immunol. 21:487–499.
1997. View Article : Google Scholar
|
|
3
|
Manolagas SC: From estrogen-centric to
aging and oxidative stress: A revised perspective of the
pathogenesis of osteoporosis. Endocr Rev. 31:266–300. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Muthusami S, Ramachandran I, Muthusamy B,
Vasudevan G, Prabhu V, Subramaniam V, Jagadeesan A and Narasimhan
S: Ovariectomy induces oxidative stress and impairs bone
antioxidant system in adult rats. Clin Chim Acta. 360:81–86. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Cervellati C, Bonaccorsi G, Cremonini E,
Bergamini CM, Patella A, Castaldini C, Ferrazzini S, Capatti A,
Picarelli V, Pansini FS, et al: Bone mass density selectively
correlates with serum markers of oxidative damage in
post-menopausal women. Clin Chem Lab Med. 51:333–338. 2013.
View Article : Google Scholar
|
|
6
|
Baek KH, Oh KW, Lee WY, Lee SS, Kim MK,
Kwon HS, Rhee EJ, Han JH, Song KH, Cha BY, et al: Association of
oxidative stress with postmenopausal osteoporosis and the effects
of hydrogen peroxide on osteoclast formation in human bone marrow
cell cultures. Calcif Tissue Int. 87:226–235. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Yalin S, Bagis S, Polat G, Dogruer N, Cenk
Aksit S, Hatungil R and Erdogan C: Is there a role of free oxygen
radicals in primary male osteoporosis. Clin Exp Rheumatol.
23:689–692. 2005.PubMed/NCBI
|
|
8
|
Halliwell B: Free radicals, antioxidants,
and human disease: Curiosity, cause, or consequence? Lancet.
344:721–724. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Bai XC, Lu D, Liu AL, Zhang ZM, Li XM, Zou
ZP, Zeng WS, Cheng BL and Luo SQ: Reactive oxygen species
stimulates receptor activator of NF-kappaB ligand expression in
osteoblast. J Biol Chem. 280:17497–17506. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Lee NK, Choi YG, Baik JY, Han SY, Jeong
DW, Bae YS, Kim N and Lee SY: A crucial role for reactive oxygen
species in RANKL-induced osteoclast differentiation. Blood.
106:852–859. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Bartell SM, Kim HN, Ambrogini E, Han L,
Iyer S, Serra Ucer S, Rabinovitch P, Jilka RL, Weinstein RS, Zhao
H, et al: FoxO proteins restrain osteoclastogenesis and bone
resorption by attenuating H2O2 accumulation.
Nat Commun. 5:37732014. View Article : Google Scholar
|
|
12
|
Rached MT, Kode A, Xu L, Yoshikawa Y, Paik
JH, Depinho RA and Kousteni S: FoxO1 is a positive regulator of
bone formation by favoring protein synthesis and resistance to
oxidative stress in osteoblasts. Cell Metab. 11:147–160. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Liu JW, Chandra D, Rudd MD, Butler AP,
Pallotta V, Brown D, Coffer PJ and Tang DG: Induction of
prosurvival molecules by apoptotic stimuli: Involvement of FOXO3a
and ROS. Oncogene. 24:2020–2031. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Lehtinen MK, Yuan Z, Boag PR, Yang Y,
Villén J, Becker EB, DiBacco S, de la Iglesia N, Gygi S, Blackwell
TK, et al: A conserved MST-FOXO signaling pathway mediates
oxidative-stress responses and extends life span. Cell.
125:987–1001. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Nemoto S and Finkel T: Redox regulation of
forkhead proteins through a p66shc-dependent signaling pathway.
Science. 295:2450–2452. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Huang H and Tindall DJ: Dynamic FoxO
transcription factors. J Cell Sci. 120:2479–2487. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Sengupta A, Molkentin JD, Paik JH, DePinho
RA and Yutzey KE: FoxO transcription factors promote cardiomyocyte
survival upon induction of oxidative stress. J Biol Chem.
286:7468–7478. 2011. View Article : Google Scholar :
|
|
18
|
Subauste AR and Burant CF: Role of FoxO1
in FFA-induced oxidative stress in adipocytes. Am J Physiol
Endocrinol Metab. 293:E159–E164. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tothova Z, Kollipara R, Huntly BJ, Lee BH,
Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams
IR, Sears C, et al: FoxOs are critical mediators of hematopoietic
stem cell resistance to physiologic oxidative stress. Cell.
128:325–339. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
de Keizer PL, Burgering BM and Dansen TB:
Forkhead box o as a sensor, mediator, and regulator of redox
signaling. Antioxid Redox Signal. 14:1093–1106. 2011. View Article : Google Scholar
|
|
21
|
Vijayan V, Khandelwal M, Manglani K, Singh
RR, Gupta S and Surolia A: Homocysteine alters the
osteoprotegerin/RANKL system in the osteoblast to promote bone
loss: Pivotal role of the redox regulator forkhead O1. Free Radic
Biol Med. 61:72–84. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Csiszar A: Anti-inflammatory effects of
resveratrol: Possible role in prevention of age-related
cardiovascular disease. Ann NY Acad Sci. 1215:117–122. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Baur JA, Pearson KJ, Price NL, Jamieson
HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K,
et al: Resveratrol improves health and survival of mice on a
high-calorie diet. Nature. 444:337–342. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Pearson KJ, Baur JA, Lewis KN, Peshkin L,
Price NL, Labinskyy N, Swindell WR, Kamara D, Minor RK, Perez E, et
al: Resveratrol delays age-related deterioration and mimics
transcriptional aspects of dietary restriction without extending
life span. Cell Metab. 8:157–168. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ungvari Z, Orosz Z, Rivera A, Labinskyy N,
Xiangmin Z, Olson S, Podlutsky A and Csiszar A: Resveratrol
increases vascular oxidative stress resistance. Am J Physiol Heart
Circ Physiol. 292:H2417–H2424. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ungvari Z, Bagi Z, Feher A, Recchia FA,
Sonntag WE, Pearson K, de Cabo R and Csiszar A: Resveratrol confers
endothelial protection via activation of the antioxidant
transcription factor Nrf2. Am J Physiol Heart Circ Physiol.
299:H18–H24. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Ungvari Z, Labinskyy N, Mukhopadhyay P,
Pinto JT, Bagi Z, Ballabh P, Zhang C, Pacher P and Csiszar A:
Resveratrol attenuates mitochondrial oxidative stress in coronary
arterial endothelial cells. Am J Physiol Heart Circ Physiol.
297:H1876–H1881. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Tamaki N, Cristina Orihuela-Campos R,
Inagaki Y, Fukui M, Nagata T and Ito HO: Resveratrol improves
oxidative stress and prevents the progression of periodontitis via
the activation of the Sirt1/AMPK and the Nrf2/antioxidant defense
pathways in a rat periodontitis model. Free Radic Biol Med.
75:222–229. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Bhattarai G, Poudel SB, Kook SH and Lee
JC: Resveratrol prevents alveolar bone loss in an experimental rat
model of periodontitis. Acta Biomater. 29:398–408. 2016. View Article : Google Scholar
|
|
30
|
Cottart CH, Nivet-Antoine V,
Laguillier-Morizot C and Beaudeux JL: Resveratrol bioavailability
and toxicity in humans. Mol Nutr Food Res. 54:7–16. 2010.
View Article : Google Scholar
|
|
31
|
Hsu H, Lacey DL, Dunstan CR, Solovyev I,
Colombero A, Timms E, Tan HL, Elliott G, Kelley MJ, Sarosi I, et
al: Tumor necrosis factor receptor family member RANK mediates
osteoclast differentiation and activation induced by
osteoprotegerin ligand. Proc Natl Acad Sci USA. 96:3540–3545. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Wei S, Teitelbaum SL, Wang MW and Ross FP:
Receptor activator of nuclear factor-kappa b ligand activates
nuclear factor-kappaB in osteoclast precursors. Endocrinology.
142:1290–1295. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Nakamura N, Ramaswamy S, Vazquez F,
Signoretti S, Loda M and Sellers WR: Forkhead transcription factors
are critical effectors of cell death and cell cycle arrest
downstream of PTEN. Mol Cell Biol. 20:8969–8982. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang Y and Tang XL: Effects of resveratrol
on osteoprotegerin and osteoprotegerin Ligand Expression of Femurs
in Ovariectomized Rats. Chin J Clin Pharmacol Ther. 13:266–270.
2008.
|
|
35
|
Giorgio M, Trinei M, Migliaccio E and
Pelicci PG: Hydrogen peroxide: A metabolic by-product or a common
mediator of ageing signals. Nat Rev Mol Cell Biol. 8:722–728. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Newmeyer DD and Ferguson-Miller S:
Mitochondria: Releasing power for life and unleashing the
machineries of death. Cell. 112:481–490. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Balaban RS, Nemoto S and Finkel T:
Mitochondria, oxidants, and aging. Cell. 120:483–495. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chance B, Sies H and Boveris A:
Hydroperoxide metabolism in mammalian organs. Physiol Rev.
59:527–605. 1979. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
D'Autréaux B and Toledano MB: ROS as
signalling molecules: Mechanisms that generate specificity in ROS
homeostasis. Nat Rev Mol Cell Biol. 8:813–824. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Denisova NA, Cantuti-Castelvetri I, Hassan
WN, Paulson KE and Joseph JA: Role of membrane lipids in regulation
of vulnerability to oxidative stress in PC12 cells: Implication for
aging. Free Radic Biol Med. 30:671–678. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Kong YY, Yoshida H, Sarosi I, Tan HL,
Timms E, Capparelli C, Morony S, Oliveira-dos-Santos AJ, Van G,
Itie A, et al: OPGL is a key regulator of osteoclastogenesis,
lymphocyte development and lymph-node organogenesis. Nature.
397:315–323. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
42
|
Levaot N, Ottolenghi A, Mann M,
Guterman-Ram G, Kam Z and Geiger B: Osteoclast fusion is initiated
by a small subset of RANKL-stimulated monocyte progenitors, which
can fuse to RANKL-unstimulated progenitors. Bone. 79:21–28. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Suda N, Morita I, Kuroda T and Murota S:
Participation of oxidative stress in the process of osteoclast
differentiation. Biochim Biophys Acta. 1157:318–323. 1993.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Garrett IR, Boyce BF, Oreffo RO, Bonewald
L, Poser J and Mundy GR: Oxygen-derived free radicals stimulate
osteoclastic bone resorption in rodent bone in vitro and in vivo. J
Clin Invest. 85:632–639. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Darden AG, Ries WL, Wolf WC, Rodriguiz RM
and Key LL Jr: Osteoclastic superoxide production and bone
resorption: Stimulation and inhibition by modulators of NADPH
oxidase. J Bone Miner Res. 11:671–675. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Steinbeck MJ, Appel WH Jr, Verhoeven AJ
and Karnovsky MJ: NADPH-oxidase expression and in situ production
of superoxide by osteoclasts actively resorbing bone. J Cell Biol.
126:765–772. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ha H, Kwak HB, Lee SW, Jin HM, Kim HM, Kim
HH and Lee ZH: Reactive oxygen species mediate RANK signaling in
osteoclasts. Exp Cell Res. 301:119–127. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Kim HJ, Chang EJ, Kim HM, Lee SB, Kim HD,
Kim GS and Kim HH: Antioxidant-α-lipoic acid inhibits osteoclast
differentiation by reducing nuclear factor-κB DNA binding and
prevents in vivo bone resorption induced by receptor activator of
nuclear factor-κB ligand and tumor necrosis factor-α. Free Radic
Biol Med. 40:1483–1493. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Van Der Heide LP, Hoekman MF and Smidt MP:
The ins and outs of FoxO shuttling: Mechanisms of FoxO
translocation and transcriptional regulation. Biochem J.
380:297–309. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Uddin S, Hussain AR, Siraj AK, Manogaran
PS, Al-Jomah NA, Moorji A, Atizado V, Al-Dayel F, Belgaumi A,
El-Solh H, et al: Role of phosphatidylinositol 3′-kinase/AKT
pathway in diffuse large B-cell lymphoma survival. Blood.
108:4178–4186. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Ambrogini E, Almeida M, Martin-Millan M,
Paik JH, Depinho RA, Han L, Goellner J, Weinstein RS, Jilka RL,
O'Brien CA, et al: FoxO-mediated defense against oxidative stress
in osteoblasts is indispensable for skeletal homeostasis in mice.
Cell Metab. 11:136–146. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Iyer S, Ambrogini E, Bartell SM, Han L,
Roberson PK, de Cabo R, Jilka RL, Weinstein RS, O'Brien CA,
Manolagas SC, et al: FOXOs attenuate bone formation by suppressing
Wnt signaling. J Clin Invest. 123:3409–3419. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Leibbrandt A and Penninger JM: RANK/RANKL:
Regulators of immune responses and bone physiology. Ann NY Acad
Sci. 1143:123–150. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Asagiri M and Takayanagi H: The molecular
understanding of osteoclast differentiation. Bone. 40:251–264.
2007. View Article : Google Scholar
|
|
55
|
Mandal CC, Ghosh Choudhury G and
Ghosh-Choudhury N: Phosphatidylinositol 3 kinase/Akt signal relay
cooperates with smad in bone morphogenetic protein-2-induced colony
stimulating factor-1 (CSF-1) expression and osteoclast
differentiation. Endocrinology. 150:4989–4998. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Moon JB, Kim JH, Kim K, Youn BU, Ko A, Lee
SY and Kim N: Akt induces osteoclast differentiation through
regulating the GSK3β/NFATc1 signaling cascade. J Immunol.
188:163–169. 2012. View Article : Google Scholar
|
