Journal Articles
Review
Inhibitors targeting the SUMOylation pathway: A patent review 2012‑2015 (Review)
Yanjun Zhou, Chunmei Ji, Mengda Cao, Miao Guo, Wen Huang, Weiwei Ni, Ling Meng, Haiwei Yang, Ji‑Fu Wei
Pages: 3-12 Published online on: 01 November 2017
Article
Connexin 43 in splenic lymphocytes is involved in the regulation of CD4+CD25+ T lymphocyte proliferation and cytokine production in hypertensive inflammation
Hai-Chao Zhang, Zhong-Shuang Zhang, Liang Zhang, Ai Wang, He Zhu, Li Li, Jun-Qiang Si, Xin-Zhi Li, Ke-Tao Ma
Pages: 13-24 Published online on: 20 October 2017
Article
Renoprotective effect of erythropoietin via modulation of the STAT6/MAPK/NF-κB pathway in ischemia/reperfusion injury after renal transplantation
Jinhua Zhang, Daqiang Zhao, Ning Na, Heng Li, Bin Miao, Liangqing Hong, Zhengyu Huang
Pages: 25-32 Published online on: 20 October 2017
Article
Atorvastatin protects the proliferative ability of human umbilical vein endothelial cells inhibited by angiotensin II by changing mitochondrial energy metabolism
Ye Chang, Yuan Li, Ning Ye, Xiaofan Guo, Zhao Li, Guozhe Sun, Yingxian Sun
Pages: 33-42 Published online on: 19 October 2017
Article
Proliferation of vascular smooth muscle cells under inflammation is regulated by NF-κB p65/microRNA-17/RB pathway activation
Dong Yang, Chen Sun, Jing Zhang, Shu Lin, Lin Zhao, Lun Wang, Ruoran Lin, Junyuan Lv, Shijie Xin
Pages: 43-50 Published online on: 25 October 2017
Article
Combination treatment of adipose-derived stem cells and adiponectin attenuates pulmonary arterial hypertension in rats by inhibiting pulmonary arterial smooth muscle cell proliferation and regulating the AMPK/BMP/Smad pathway Corrigendum in /10.3892/ijmm.2021.4953
Li Luo, Wuhong Zheng, Guili Lian, Huaning Chen, Ling Li, Changsheng Xu, Liangdi Xie
Pages: 51-60 Published online on: 31 October 2017
Article
Apolipoprotein C-III in the high-density lipoprotein proteome of cerebral lacunar infarction patients impairs its anti-inflammatory function
Pu Lv, Mingming Zhao, Yuanyuan Liu, Haiqiang Jin, Wei Cui, Chenghe Fan, Yuming Teng, Lemin Zheng, Yining Huang
Pages: 61-68 Published online on: 27 October 2017
Article
AMPK activation serves a critical role in mitochondria quality control via modulating mitophagy in the heart under chronic hypoxia
Huagang Zhang, Bo Liu, Tianbo Li, Yun Zhu, Guiping Luo, Yunhan Jiang, Fuqin Tang, Zhao Jian, Yingbin Xiao
Pages: 69-76 Published online on: 26 October 2017
Article
Anti-hypoglycemic and hepatocyte-protective effects of hyperoside from Zanthoxylum bungeanum leaves in mice with high-carbohydrate/high-fat diet and alloxan-induced diabetes
Yali Zhang, Mimi Wang, Huanhuan Dong, Xiaomin Yu, Jingfang Zhang
Pages: 77-86 Published online on: 25 October 2017
Article
Generation of human-induced pluripotent stem cells from burn patient-derived skin fibroblasts using a non-integrative method
Shangfeng Fu, Jianwu Ding, Dewu Liu, Heping Huang, Min Li, Yang Liu, Longxiang Tu, Deming Liu
Pages: 87-94 Published online on: 23 October 2017
Article
Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice
Tùng Nguyễn-Thanh, Dal Kim, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kang
Pages: 95-106 Published online on: 27 October 2017
Article
Detection of calprotectin in inflammatory bowel disease: Fecal and serum levels and immunohistochemical localization
Shuhei Fukunaga, Kotaro Kuwaki, Keiichi Mitsuyama, Hidetoshi Takedatsu, Shinichiro Yoshioka, Hiroshi Yamasaki, Ryosuke Yamauchi, Atsushi Mori, Tatsuyuki Kakuma, Osamu Tsuruta, Takuji Torimura
Pages: 107-118 Published online on: 07 November 2017
Article
Radical scavenging-linked anti-adipogenic activity of Alnus firma extracts
Sun-Il Choi, Jong Seok Lee, Sarah Lee, Jin-Ha Lee, Hee-Sun Yang, Joohong Yeo, Jong-Yea Kim, Boo-Yong Lee, Il-Jun Kang, Ok-Hwan Lee
Pages: 119-128 Published online on: 27 October 2017
Article
Transforming growth factor β1 promotes migration and invasion in HepG2 cells: Epithelial‑to‑mesenchymal transition via JAK/STAT3 signaling
Xiao‑Long Lin, Mihua Liu, Yuanbo Liu, Huijun Hu, Yongquan Pan, Weiwen Zou, Xiaojuan Fan, Xuemei Hu
Pages: 129-136 Published online on: 01 November 2017
Article
Cryptdin-2 predicts intestinal injury during heatstroke in mice
Jingjing Ji, Zhengtao Gu, Hui Li, Lei Su, Zhifeng Liu
Pages: 137-146 Published online on: 01 November 2017
Article
Activation of adrenergic receptor β2 promotes tumor progression and epithelial mesenchymal transition in tongue squamous cell carcinoma
Haichao Liu, Cheng Wang, Nan Xie, Zehang Zhuang, Xiqiang Liu, Jinsong Hou, Hongzhang Huang
Pages: 147-154 Published online on: 09 November 2017
Article
Histone deacetylase 3 is associated with gastric cancer cell growth via the miR-454-mediated targeting of CHD5
Guangru Xu, Hongxing Zhu, Minghui Zhang, Jinhua Xu
Pages: 155-163 Published online on: 31 October 2017
Article
YAP and TAZ mediate steroid-induced alterations in the trabecular meshwork cytoskeleton in human trabecular meshwork cells
Jie Peng, Hailian Wang, Xin Wang, Minghan Sun, Shaoping Deng, Yi Wang
Pages: 164-172 Published online on: 23 October 2017
Article
Synovial fluid‑derived synovial fragments represent an improved source of synovial mesenchymal stem cells in the temporomandibular joint
Yu Yao, Zheng‑Yu Li, Hong Zhang, You‑Hua Zheng, Li‑Xiang Mai, Wen‑Jing Liu, Zhi‑Guang Zhang, Yang‑Peng Sun
Pages: 173-183 Published online on: 25 October 2017
Article
Metabolic profiles of adipose-derived and bone marrow-derived stromal cells from elderly coronary heart disease patients by capillary liquid chromatography quadrupole time-of-flight mass spectrometry
Jian-Zhong Li, Hui Qu, Jian Wu, Fan Zhang, Zhi-Bo Jia, Jian-Yong Sun, Bo Lv, Yue Kang, Shu-Lin Jiang, Kai Kang
Pages: 184-194 Published online on: 19 October 2017
Article
A novel method of neural differentiation of PC12 cells by using Opti-MEM as a basic induction medium
Rendong Hu, Qiaoyu Cao, Zhongqing Sun, Jinying Chen, Qing Zheng, Fei Xiao
Pages: 195-201 Published online on: 19 October 2017
Article
Resveratrol prevents osteoporosis by upregulating FoxO1 transcriptional activity
Yan-Ling Feng, Xiao-Tong Jiang, Fang-Fang Ma, Jie Han, Xu-Lei Tang
Pages: 202-212 Published online on: 23 October 2017
Article
Long non‑coding RNA DANCR regulates the proliferation and osteogenic differentiation of human bone-derived marrow mesenchymal stem cells via the p38 MAPK pathway
Jinlong Zhang, Zhiwen Tao, Yuli Wang
Pages: 213-219 Published online on: 27 October 2017
Article
Genome-wide DNA methylome alterations in acute coronary syndrome
Dandan Li, Jing Yan, Yunlong Yuan, Cheng Wang, Jia Wu, Qingwen Chen, Jiaxi Song, Junjun Wang
Pages: 220-232 Published online on: 27 October 2017
Article
Luteolin inhibits multi-heavy metal mixture-induced HL7702 cell apoptosis through downregulation of ROS-activated mitochondrial pathway
Yafei Wang, Hong Su, Xin Song, Samuel Selorm Fiati Kenston, Jinshun Zhao, Yuanliang Gu
Pages: 233-241 Published online on: 27 October 2017
Article
Neuroprotective effects of hydrogen sulfide on sodium azide-induced oxidative stress in PC12 cells
Cheng Gao, Pan Chang, Lijun Yang, Yi Wang, Shaohua Zhu, Haiyan Shan, Mingyang Zhang, Luyang Tao
Pages: 242-250 Published online on: 01 November 2017
Article
Lychee seed extract protects against neuronal injury and improves cognitive function in rats with type II diabetes mellitus with cognitive impairment
Yong Tang, Chonglin Yu, Jianming Wu, Haixia Chen, Yuan Zeng, Xiuling Wang, Le Yang, Qibing Mei, Shousong Cao, Dalian Qin
Pages: 251-263 Published online on: 09 November 2017
Article
Schisandrin A suppresses lipopolysaccharide-induced inflammation and oxidative stress in RAW 264.7 macrophages by suppressing the NF-κB, MAPKs and PI3K/Akt pathways and activating Nrf2/HO-1 signaling
Da Hye Kwon, Hee-Jae Cha, Eun Ok Choi, Sun-Hee Leem, Gi-Young Kim, Sung-Kwon Moon, Young-Chae Chang, Seok-Joong Yun, Hye Jin Hwang, Byung Woo Kim, Wun-Jae Kim, Yung Hyun Choi
Pages: 264-274 Published online on: 25 October 2017
Article
Fibroblast activation protein-α promotes the growth and migration of lung cancer cells via the PI3K and sonic hedgehog pathways
Jun Jia, Tracey A. Martin, Lin Ye, Lin Meng, Nan Xia, Wen G. Jiang, Xiaodong Zhang
Pages: 275-283 Published online on: 27 October 2017
Article
Suppression of microRNA-130b inhibits glioma cell proliferation and invasion, and induces apoptosis by PTEN/AKT signaling
Jian-Jun Gu, Kai-Chun Fan, Jian-He Zhang, Hong-Jie Chen, Shou-Sen Wang
Pages: 284-292 Published online on: 02 November 2017
Article
Alterations of protein glycosylation in embryonic stem cells during adipogenesis
Wenguang Liu, Xingrong Yan, Wei Liu, Yangyang Wang, Yang Rao, Hanjie Yu, Jihong Cui, Xin Xie, Mei Sun, Lu Yin, Hongmin Li, Fulin Chen
Pages: 293-301 Published online on: 07 November 2017
Article
Expression profile analysis of long non-coding RNAs involved in the metformin-inhibited gluconeogenesis of primary mouse hepatocytes
Yao Wang, Hongju Tang, Xueying Ji, Yuqing Zhang, Wan Xu, Xue Yang, Ruyuan Deng, Yun Liu, Fengying Li, Xiao Wang, Libin Zhou
Pages: 302-310 Published online on: 07 November 2017
Article
Global gene expression analysis combined with a genomics approach for the identification of signal transduction networks involved in postnatal mouse myocardial proliferation and development
Ruoxin Wang, Chao Su, Xinting Wang, Qiang Fu, Xingjie Gao, Chunyan Zhang, Jie Yang, Xi Yang, Minxin Wei
Pages: 311-321 Published online on: 03 November 2017
Article
Reactive oxygen species induce injury of the intestinal epithelium during hyperoxia
Min Zhao, Shimiao Tang, Junchi Xin, Yingliang Wei, Dongyan Liu
Pages: 322-330 Published online on: 09 November 2017
Article
Hey1 functions as a positive regulator of odontogenic differentiation in odontoblast‑lineage cells
Xiao Yin, Zhaobin Zeng, Jinliang Xing, Ansheng Zhang, Wenkai Jiang, Wei Wang, Hantang Sun, Longxing Ni
Pages: 331-339 Published online on: 13 November 2017
Article
Broadleaf Mahonia attenuates granulomatous lobular mastitis‑associated inflammation by inhibiting CCL‑5 expression in macrophages
Zhiyu Wang, Neng Wang, Xiaoyan Liu, Qi Wang, Biao Xu, Pengxi Liu, Huayu Zhu, Jianping Chen, Honglin Situ, Yi Lin
Pages: 340-352 Published online on: 09 November 2017
Article
In vitro investigation of the mechanism underlying the effect of ginsenoside on the proliferation and differentiation of neural stem cells subjected to oxygen-glucose deprivation/reperfusion
Jian Gao, Huajing Bai, Qiang Li, Jian Li, Feng Wan, Mo Tian, Yuanyuan Li, Yilun Song, Jianping Zhang, Yinchu Si
Pages: 353-363 Published online on: 13 November 2017
Article
Vitamin D receptor activation influences the ERK pathway and protects against neurological deficits and neuronal death
Jie Yuan, Xin Guo, Zhengang Liu, Xiuqin Zhao, Yan Feng, Sixin Song, Changmeng Cui, Pei Jiang
Pages: 364-372 Published online on: 09 November 2017
Article
Herbal prescription, Danggui-Sayuk-Ga-Osuyu-Senggang-Tang, inhibits TNF-α-induced epithelial-mesenchymal transition in HCT116 colorectal cancer cells
Kangwook Lee, Sung-Gook Cho, Youn Kyung Choi, Yu-Jeong Choi, Gyu-Ri Lee, Chan-Yong Jeon, Seong-Gyu Ko
Pages: 373-380 Published online on: 07 November 2017
Article
CCDC134 serves a crucial role in embryonic development
Biaoyi Yu, Tianzhuo Zhang, Peng Xia, Xiaoting Gong, Xiaoyan Qiu, Jing Huang
Pages: 381-390 Published online on: 19 October 2017
Article
Anti-inflammatory effects of a methanolic extract of Castanea seguinii Dode in LPS-induced RAW264.7 macrophage cells
Yourim Lim, Ji-Won Park, Ok-Kyoung Kwon, Jae-Won Lee, Han-Sol Lee, Sangwoo Lee, Sangho Choi, Wanyi Li, Hang Jin, Sang-Bae Han, Kyung-Seop Ahn
Pages: 391-398 Published online on: 27 October 2017
Article
The inhibition of MyD88 and TRIF signaling serve equivalent roles in attenuating myocardial deterioration due to acute severe inflammation
Min-Zhi Ouyang, Dan Zhou, Yun Zhu, Ming Zhang, Ling Li
Pages: 399-408 Published online on: 07 November 2017
Article
Angiotensin-converting enzyme 2-angiotensin (1-7)-Mas axis prevents pancreatic acinar cell inflammatory response via inhibition of the p38 mitogen-activated protein kinase/nuclear factor-κB pathway
Xiaozheng Yu, Lijian Cui, Fei Hou, Xiaoya Liu, Yan Wang, Yan Wen, Cheng Chi, Chunyun Li, Ruixia Liu, Chenghong Yin
Pages: 409-420 Published online on: 13 November 2017
Article
Effect on the dopaminergic metabolism induced by oral exposure to simazine during the prepubertal period in rats
Xueting Li, Jia Yu, Yanping Wu, Baixiang Li
Pages: 421-429 Published online on: 20 October 2017
Article
Inhibition of Rho kinase protects against colitis in mice by attenuating intestinal epithelial barrier dysfunction via MLC and the NF-κB pathway
Yanting Zou, Lili Ma, Yuan Zhao, Shuncai Zhang, Chaohui Zhou, Yu Cai
Pages: 430-438 Published online on: 19 October 2017
Article
High glucose upregulates endothelin type B receptors in vascular smooth muscle cells via the downregulation of Sirt1
Yan Lin, Yan Zhao, Enqi Liu
Pages: 439-445 Published online on: 07 November 2017
Article
Mechanism of long non-coding RNA MALAT1 in lipopolysaccharide-induced acute kidney injury is mediated by the miR-146a/NF-κB signaling pathway
Ying Ding, Feng Guo, Tao Zhu, Jun Li, Danyan Gu, Weiliang Jiang, Yuying Lu, Daoyang Zhou
Pages: 446-454 Published online on: 02 November 2017
Article
Persistent STAT5-mediated ROS production and involvement of aberrant p53 apoptotic signaling in the resistance of chronic myeloid leukemia to imatinib
Yanhong Cheng, Yingchan Hao, Aimei Zhang, Chaojie Hu, Xiaoxiao Jiang, Quan Wu, Xiucai Xu
Pages: 455-463 Published online on: 20 October 2017
Article
Hesperidin induces apoptosis and G0/G1 arrest in human non-small cell lung cancer A549 cells
Rongmu Xia, Xin Sheng, Xianlin Xu, Chunbo Yu, Hongling Lu
Pages: 464-472 Published online on: 09 November 2017
Article
Induced pluripotent stem cell-conditioned medium suppresses pulmonary fibroblast-to-myofibroblast differentiation via the inhibition of TGF-β1/Smad pathway
Yan Zhou, Qiang Zhang, Yuan Gao, Mingqi Tan, Rui Zheng, Li Zhao, Xiaoye Zhang
Pages: 473-484 Published online on: 19 October 2017
Article
Antinociceptive effect of Valeriana fauriei regulates BDNF signaling in an animal model of fibromyalgia
Hwayoung Lee, Jiyun Im, Hansol Won, Jun Young Kim, Hyung‑Ki Kim, Jun‑Tack Kwon, Young Ock Kim, Sanghyun Lee, Ik‑Hyun Cho, Sang Won Lee, Hak‑Jae Kim
Pages: 485-492 Published online on: 20 October 2017
Article
Downregulation of microRNA‑124‑3p suppresses the mTOR signaling pathway by targeting DDIT4 in males with major depressive disorder
Qiuling Wang, Gaofeng Zhao, Zhenzhen Yang, Xia Liu, Ping Xie
Pages: 493-500 Published online on: 06 November 2017
Article
MicroRNA-142-3p relieves neuropathic pain by targeting high mobility group box 1
Yang Zhang, Junying Mou, Li Cao, Su Zhen, Hongjuan Huang, Hongguang Bao
Pages: 501-510 Published online on: 27 October 2017
Article
Protein extracted from Porphyra yezoensis prevents cisplatin-induced nephrotoxicity by downregulating the MAPK and NF-κB pathways
In-Hye Kim, Mi-Jin Kwon, Jae-Hun Jung, Taek-Jeong Nam
Pages: 511-520 Published online on: 26 October 2017
Article
Anti-neuroinflammatory effect of curcumin on Pam3CSK4-stimulated microglial cells
Meiling Jin, Sun Young Park, Qian Shen, Yihong Lai, Xingmei Ou, Zhuo Mao, Dongxu Lin, Yangyang Yu, Weizhen Zhang
Pages: 521-530 Published online on: 27 October 2017
Article
Vibrio vulnificus infection induces the maturation and activation of dendritic cells with inflammatory Th17-polarizing ability
Arim Lee, Hui Xuan Lim, Myun Soo Kim, Daeho Cho, Kyung Ku Jang, Sang Ho Choi, Tae Sung Kim
Pages: 531-540 Published online on: 01 November 2017
Article
Peanut arachidin-1 enhances Nrf2-mediated protective mechanisms against TNF-α-induced ICAM-1 expression and NF-κB activation in endothelial cells
Lih-Geeng Chen, Yu-Qi Zhang, Zhi-Zhen Wu, Chia-Wen Hsieh, Chi-Shih Chu, Being-Sun Wung
Pages: 541-547 Published online on: 07 November 2017
Article
Low-dose irradiation inhibits proliferation of the p53null type human prostate cancer cells through the ATM/p21 pathway
Si-Jie Li, Xin-Yue Liang, Hai-Jun Li, Guo-Zi Yang, Wei Li, Zhuo Li, Lei Zhou, Xue Wen, De-Hai Yu, Jiu-Wei Cui
Pages: 548-554 Published online on: 07 November 2017
Article
