|
1
|
Ning G: Decade in review-type 2 diabetes
mellitus: At the centre of things. Nat Rev Endocrinol. 11:636–638.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Kitamura Y and Accili D: New insights into
the integrated physiology of insulin action. Rev Endocr Metab
Disord. 5:143–149. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Accili D: Lilly lecture 2003: The struggle
for mastery in insulin action: From triumvirate to republic.
Diabetes. 53:1633–1642. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Mercer TR, Dinger ME and Mattick JS: Long
non-coding RNAs: Insights into functions. Nat Rev Genet.
10:155–159. 2009. View
Article : Google Scholar : PubMed/NCBI
|
|
5
|
Guttman M and Rinn JL: Modular regulatory
principles of large non-coding RNAs. Nature. 482:339–346. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wang KC and Chang HY: Molecular mechanisms
of long noncoding RNAs. Mol Cell. 43:904–914. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Morán I, Akerman I, van de Bunt M, Xie R,
Benazra M, Nammo T, Arnes L, Nakić N, García-Hurtado J,
Rodríguez-Seguí S, et al: Human β cell transcriptome analysis
uncovers lncRNAs that are tissue-specific, dynamically regulated,
and abnormally expressed in type 2 diabetes. Cell Metab.
16:435–448. 2012. View Article : Google Scholar
|
|
8
|
Sun L, Goff LA, Trapnell C, Alexander R,
Lo KA, Hacisuleyman E, Sauvageau M, Tazon-Vega B, Kelley DR,
Hendrickson DG, et al: Long noncoding RNAs regulate adipogenesis.
Proc Natl Acad Sci USA. 110:3387–3392. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Gao Y, Wu F, Zhou J, Yan L, Jurczak MJ,
Lee HY, Yang L, Mueller M, Zhou XB, Dandolo L, et al: The H19/let-7
double-negative feedback loop contributes to glucose metabolism in
muscle cells. Nucleic Acids Res. 42:13799–13811. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Pilkis SJ, el-Maghrabi MR and Claus TH:
Hormonal regulation of hepatic gluconeogenesis and glycolysis. Annu
Rev Biochem. 57:755–783. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chan JC, Deerochanawong C, Shera AS, Yoon
KH, Adam JM, Ta VB, Chan SP, Fernando RE, Horn LC, Nguyen TK, et
al: Role of metformin in the initiation of pharmacotherapy for type
2 diabetes: An Asian-Pacific perspective. Diabetes Res Clin Pract.
75:255–266. 2007. View Article : Google Scholar
|
|
12
|
Inzucchi SE, Maggs DG, Spollett GR, Page
SL, Rife FS, Walton V and Shulman GI: Efficacy and metabolic
effects of metformin and troglitazone in type II diabetes mellitus.
N Engl J Med. 338:867–872. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shaw RJ, Lamia KA, Vasquez D, Koo SH,
Bardeesy N, Depinho RA, Montminy M and Cantley LC: The kinase LKB1
mediates glucose homeostasis in liver and therapeutic effects of
metformin. Science. 310:1642–1646. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Foretz M, Hébrard S, Leclerc J,
Zarrinpashneh E, Soty M, Mithieux G, Sakamoto K, Andreelli F and
Viollet B: Metformin inhibits hepatic gluconeogenesis in mice
independently of the LKB1/AMPK pathway via a decrease in hepatic
energy state. J Clin Invest. 120:2355–2369. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Madiraju AK, Erion DM, Rahimi Y, Zhang XM,
Braddock DT, Albright RA, Prigaro BJ, Wood JL, Bhanot S, MacDonald
MJ, et al: Metformin suppresses gluconeogenesis by inhibiting
mitochondrial glycerophosphate dehydrogenase. Nature. 510:542–546.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2-ΔΔCT method. Methods. 25:402–408. 2001. View Article : Google Scholar
|
|
17
|
Yoon JC, Puigserver P, Chen G, Donovan J,
Wu Z, Rhee J, Adelmant G, Stafford J, Kahn CR, Granner DK, et al:
Control of hepatic gluconeogenesis through the transcriptional
coactivator PGC-1. Nature. 413:131–138. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Ponjavic J, Oliver PL, Lunter G and
Ponting CP: Genomic and transcriptional co-localization of
protein-coding and long non-coding RNA pairs in the developing
brain. PLoS Genet. 5:e10006172009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Nordlie RC, Foster JD and Lange AJ:
Regulation of glucose production by the liver. Annu Rev Nutr.
19:379–406. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Pilkis SJ and Granner DK: Molecular
physiology of the regulation of hepatic gluconeogenesis and
glycolysis. Annu Rev Physiol. 54:885–909. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Gonzalez GA and Montminy MR: Cyclic AMP
stimulates somatostatin gene transcription by phosphorylation of
CREB at serine 133. Cell. 59:675–680. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lee JT and Bartolomei MS: X-inactivation,
imprinting, and long noncoding RNAs in health and disease. Cell.
152:1308–1323. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Faghihi MA, Modarresi F, Khalil AM, Wood
DE, Sahagan BG, Morgan TE, Finch CE, St Laurent G III, Kenny PJ and
Wahlestedt C: Expression of a noncoding RNA is elevated in
Alzheimer's disease and drives rapid feed-forward regulation of
beta-secretase. Nat Med. 14:723–730. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Archer K, Broskova Z, Bayoumi AS, Teoh JP,
Davila A, Tang Y, Su H and Kim IM: Long non-coding RNAs as master
regulators in cardiovascular diseases. Int J Mol Sci.
16:23651–23667. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ding GL, Wang FF, Shu J, Tian S, Jiang Y,
Zhang D, Wang N, Luo Q, Zhang Y, Jin F, et al: Transgenerational
glucose intolerance with Igf2/H19 epigenetic alterations in mouse
islet induced by intrauterine hyperglycemia. Diabetes.
61:1133–1142. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Yang G, Lu X and Yuan L: LncRNA: A link
between RNA and cancer. Biochim Biophys Acta. 1839:1097–1109. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhao XY and Lin JD: Long noncoding RNAs: A
new regulatory code in metabolic control. Trends Biochem Sci.
40:586–596. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Fadista J, Vikman P, Laakso EO, Mollet IG,
Esguerra JL, Taneera J, Storm P, Osmark P, Ladenvall C, Prasad RB,
et al: Global genomic and transcriptomic analysis of human
pancreatic islets reveals novel genes influencing glucose
metabolism. Proc Natl Acad Sci USA. 111:13924–13929. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Cao J, Meng S, Chang E, Beckwith-Fickas K,
Xiong L, Cole RN, Radovick S, Wondisford FE and He L: Low
concentrations of metformin suppress glucose production in
hepatocytes through AMP-activated protein kinase (AMPK). J Biol
Chem. 289:20435–20446. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Herzig S, Long F, Jhala US, Hedrick S,
Quinn R, Bauer A, Rudolph D, Schutz G, Yoon C, Puigserver P, et al:
CREB regulates hepatic gluconeogenesis through the coactivator
PGC-1. Nature. 413:179–183. 2001. View
Article : Google Scholar : PubMed/NCBI
|
|
31
|
Puigserver P, Rhee J, Donovan J, Walkey
CJ, Yoon JC, Oriente F, Kitamura Y, Altomonte J, Dong H, Accili D,
et al: Insulin-regulated hepatic gluconeogenesis through
FOXO1-PGC-1alpha interaction. Nature. 423:550–555. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Koo SH, Flechner L, Qi L, Zhang X,
Screaton RA, Jeffries S, Hedrick S, Xu W, Boussouar F, Brindle P,
et al: The CREB coactivator TORC2 is a key regulator of fasting
glucose metabolism. Nature. 437:1109–1111. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Kobayashi M, Ohno T, Ihara K, Murai A,
Kumazawa M, Hoshino H, Iwanaga K, Iwai H, Hamana Y, Ito M, et al:
Searching for genomic region of high-fat diet-induced type 2
diabetes in mouse chromosome 2 by analysis of congenic strains.
PLoS One. 9:e962712014. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Feng J, Bi C, Clark BS, Mady R, Shah P and
Kohtz JD: The Evf-2 noncoding RNA is transcribed from the Dlx-5/6
ultraconserved region and functions as a Dlx-2 transcriptional
coactivator. Genes Dev. 20:1470–1484. 2006. View Article : Google Scholar : PubMed/NCBI
|
