|
1
|
Ley B, Collard HR and King TE Jr: Clinical
course and prediction of survival in idiopathic pulmonary fibrosis.
Am J Respir Crit Care Med. 183:431–440. 2011. View Article : Google Scholar
|
|
2
|
Richeldi L, Costabel U, Selman M, Kim DS,
Hansell DM, Nicholson AG, Brown KK, Flaherty KR, Noble PW, Raghu G,
et al: Efficacy of a tyrosine kinase inhibitor in idiopathic
pulmonary fibrosis. N Engl J Med. 365:1079–1087. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelialmesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Arias AM: Epithelial mesenchymal
interactions in cancer and development. Cell. 105:425–431. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Meng XM, Nikolic-Paterson DJ and Lan HY:
TGF-β: The master regulator of fibrosis. Nat Rev Nephrol.
12:325–338. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Pirozzi G, Tirino V, Camerlingo R, Franco
R, La Rocca A, Liguori E, Martucci N, Paino F, Normanno N and Rocco
G: Epithelial to mesenchymal transition by TGFβ-1 induction
increases stemness characteristics in primary non small cell lung
cancer cell line. PLoS On. 6:e215482011. View Article : Google Scholar
|
|
7
|
Yang G, Liang Y, Zheng T, Song R, Wang J,
Shi H, Sun B, Xie C, Li Y, Han J, et al: FCN2 inhibits
epithelial-mesenchymal transition-induced metastasis of
hepatocellular carcinoma via TGF-β/Smad signaling. Cancer Lett.
378:80–86. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Flanders KC: Smad3 as a mediator of the
fibrotic response. Int J Exp Pathol. 85:47–64. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Xu F, Liu C, Zhou D and Zhang L:
TGF-β/SMAD pathway and its regulation in hepatic fibrosis. J
Histochem Cytochem. 64:157–167. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen Y, Wang C, Huang Q, Wu D, Cao J, Xu
X, Yang C and Li X: Caveolin-1 plays an important role in the
differentiation of bone marrow-derived mesenchymal stem cells into
cardiomyocytes. Cardiology. 136:40–48. 2017. View Article : Google Scholar
|
|
11
|
Nagaya N, Kangawa K, Itoh T, Iwase T,
Murakami S, Miyahara Y, Fujii T, Uematsu M, Ohgushi H, Yamagishi M,
et al: Transplantation of mesenchymal stem cells improves cardiac
function in a rat model of dilated cardiomyopathy. Circulation.
112:1128–1135. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Mezey E: The therapeutic potential of bone
marrow-derived stromal cells. J Cell Biochem. 112:2683–2687. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Oh JY, Kim MK, Shin MS, Lee HJ, Ko JH, Wee
WR and Lee JH: The anti-inflammatory and anti-angiogenic role of
mesenchymal stem cells in corneal wound healing following chemical
injury. Stem Cells. 26:1047–1055. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Shi M, Liu ZW and Wang FS:
Immunomodulatory properties and therapeutic application of
mesenchymal stem cells. Clin Exp Immunol. 164:1–8. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Chiesa S, Morbelli S, Morando S, Massollo
M, Marini C, Bertoni A, Frassoni F, Bartolomé ST, Sambuceti G,
Traggiai E, et al: Mesenchymal stem cells impair in vivo T-cell
priming by dendritic cells. Proc Natl Acad Sci USA.
108:17384–17389. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Suganuma S, Tada K, Hayashi K, Takeuchi A,
Sugimoto N, Ikeda K and Tsuchiya H: Uncultured adipose-derived
regenerative cells promote peripheral nerve regeneration. J Orthop
Sci. 18:145–151. 2013. View Article : Google Scholar
|
|
17
|
Chen L, Tredget EE, Wu PY and Wu Y:
Paracrine factors of mesenchymal stem cells recruit macrophages and
endothelial lineage cells and enhance wound healing. PLoS On.
3:e18862008. View Article : Google Scholar
|
|
18
|
Li X, Luo Q, Sun J and Song G: Conditioned
medium from mesenchymal stem cells enhances the migration of
hepatoma cells through CXCR4 upregulation and F-actin remodeling.
Biotechnol Lett. 37:511–521. 2015. View Article : Google Scholar
|
|
19
|
Zhao MM, Cui JZ, Cui Y, Li R, Tian YX,
Song SX, Zhang J and Gao JL: Therapeutic effect of exogenous bone
marrow derived mesenchymal stem cell transplantation on silicosis
via paracrine mechanisms in rats. Mol Med Rep. 8:741–746. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Watanabe-Takano H, Takano K, Hatano M,
Tokuhisa T and Endo T: DA-Raf-mediated suppression of the Ras-ERK
pathway is essential for TGF-β1-induced epithelial-mesenchymal
transition in alveolar epithelial type 2 cells. PloS On.
10:e01278882015. View Article : Google Scholar
|
|
21
|
Yeh YC, Wei WC, Wang YK, Lin SC, Sung JM
and Tang MJ: Transforming growth factor-{beta}1 induces
Smad3-dependent {beta}1 integrin gene expression in
epithelial-to-mesenchymal transition during chronic
tubulointerstitial fibrosis. Am J Pathol. 177:1743–1754. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Willis BC and Borok Z: TGF-beta-induced
EMT: mechanisms and implications for fibrotic lung disease. Am J
Physiol Lung Cell Mol Physiol. 293:L525–L534. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Thiery JP: Epithelial-mesenchymal
transitions in cancer onset and progression. Bull Acad Natl Med.
193:1969–1979. 2009.In French.
|
|
24
|
Carew RM, Wang B and Kantharidis P: The
role of EMT in renal fibrosis. Cell Tissue Res. 347:103–116. 2012.
View Article : Google Scholar
|
|
25
|
Hosper NA, van den Berg PP, de Rond S,
Popa ER, Wilmer MJ, Masereeuw R and Bank RA:
Epithelial-to-mesenchymal transition in fibrosis: Collagen type I
expression is highly upregulated after EMT, but does not contribute
to collagen deposition. Exp Cell Res. 319:3000–3009. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wettstein G, Bellaye PS, Kolb M, Hammann
A, Crestani B, Soler P, Marchal-Somme J, Hazoume A, Gauldie J,
Gunther A, et al: Inhibition of HSP27 blocks fibrosis development
and EMT features by promoting Snail degradation. FASEB J.
27:1549–1560. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Perez RE, Navarro A, Rezaiekhaligh MH,
Mabry SM and Ekekezie II: TRIP-1 regulates TGF-β1-induced
epithelialmesenchymal transition of human lung epithelial cell line
A549. Am J Physiol Lung Cell Mol Physiol. 300:L799–L807. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
He X, Young SH, Schwegler-Berry D,
Chisholm WP, Fernback JE and Ma Q: Multiwalled carbon nanotubes
induce a fibrogenic response by stimulating reactive oxygen species
production, activating NF-κB signaling, and promoting
fibroblast-to-myofibroblast transformation. Chem Res Toxicol.
24:2237–2248. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Aschner Y and Downey GP: Transforming
growth factor-β: Master regulator of the respiratory system in
health and disease. Am J Respir Cell Mol Biol. 54:647–655. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Tamminen JA, Myllärniemi M, Hyytiäinen M,
Keski-Oja J and Koli K: Asbestos exposure induces alveolar
epithelial cell plasticity through MAPK/Erk signaling. J Cell
Biochem. 113:2234–2247. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zhang YE: Non-Smad pathways in TGF-β
signaling. Cell Res. 19:128–139. 2009. View Article : Google Scholar :
|
|
32
|
Reyes-Reyes EM, Ramos IN, Tavera-Garcia MA
and Ramos KS: The aryl hydrocarbon receptor agonist benzo(a)pyrene
reactivates LINE-1 in HepG2 cells through canonical TGF-β1
signaling: Implications in hepatocellular carcinogenesis. Am J
Cancer Res. 6:1066–1077. 2016.
|
|
33
|
Derynck R and Zhang YE: Smad-dependent and
Smad-independent pathways in TGF-β family signalling. Nature.
425:577–584. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang C, Song X, Li Y, Han F, Gao S, Wang
X, Xie S and Lv C: Low-dose paclitaxel ameliorates pulmonary
fibrosis by suppressing TGF-β1/Smad3 pathway via miR-140
upregulation. PLoS One. 8:e707252013. View Article : Google Scholar
|
|
35
|
Xie L, Zhou D, Xiong J, You J, Zeng Y and
Peng L: Paraquat induce pulmonary epithelial-mesenchymal transition
through transforming growth factor-β1-dependent mechanism. Exp
Toxicol Pathol. 68:69–76. 2016. View Article : Google Scholar
|
|
36
|
Liu L, Wang Y, Yan R, Li S, Shi M, Xiao Y
and Guo B: Oxymatrine inhibits renal tubular EMT induced by high
glucose via upregulation of SnoN and inhibition of TGF-β1/Smad
signaling pathway. PLoS On. 11:e01519862016. View Article : Google Scholar
|
|
37
|
Dong Z, Tai W, Lei W, Wang Y, Li Z and
Zhang T: IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal
transition in alveolar epithelial cells. BMC Cell Biol. 17:72016.
View Article : Google Scholar
|
|
38
|
Zhang L, Cheng X, Gao Y, Zhang C, Bao J,
Guan H, Yu H, Lu R, Xu Q and Sun Y: Curcumin inhibits metastasis in
human papillary thyroid carcinoma BCPAP cells via downregulation of
the TGF-β/Smad2/3 signaling pathway. Exp Cell Res. 341:157–165.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Kong D, Zhang F, Shao J, Wu L, Zhang X,
Chen L, Lu Y and Zheng S: Curcumin inhibits cobalt chloride-induced
epithelial- to-mesenchymal transition associated with interference
with TGF-β/Smad signaling in hepatocytes. Lab Invest. 95:1234–1245.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Masszi A and Kapus A: Smaddening
complexity: The role of Smad3 in epithelial-myofibroblast
transition. Cells Tissues Organs. 193:41–52. 2011. View Article : Google Scholar
|
|
41
|
Chen Z, Mei Y, Lei H, Tian R, Ni N, Han F,
Gan S and Sun S: LYTAK1, a TAK1 inhibitor, suppresses proliferation
and epithelial mesenchymal transition in retinal pigment epithelium
cells. Mol Med Rep. 14:145–150. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Smith KA, Zhou B, Avdulov S, Benyumov A,
Peterson M, Liu Y, Okon A, Hergert P, Braziunas J, Wagner CR, et
al: Transforming growth factor-1 induced epithelial mesenchymal
transition is blocked by a chemical antagonist of translation
factor eIF4E. Sci Rep. 5:182332015. View Article : Google Scholar
|
|
43
|
Xu J, Lamouille S and Derynck R:
TGF-beta-induced epithelial to mesenchymal transition. Cell Res.
19:156–172. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Zavadil J, Cermak L, Soto-Nieves N and
Böttinger EP: Integration of TGF-beta/Smad and Jagged1/Notch
signalling in epithelial-to-mesenchymal transition. EMBO J.
23:1155–1165. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Wang ZC, Yang S, Huang JJ, Chen SL, Li QQ
and Li Y: Effect of bone marrow mesenchymal stem cells on the Smad
expression of hepatic fibrosis rats. Asian Pac J Trop Med.
7:321–324. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Lang H and Dai C: Effects of bone marrow
mesenchymal stem cells on plasminogen activator inhibitor-1 and
renal fibrosis in rats with diabetic nephropathy. Arch Med Res.
47:71–77. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Cai B, Tan X, Zhang Y, Li X, Wang X, Zhu
J, Wang Y, Yang F, Wang B, Liu Y, et al: Mesenchymal stem cells and
cardiomyocytes interplay to prevent myocardial hypertrophy. Stem
Cells Transl Med. 4:1425–1435. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Jang YO, Kim MY, Cho MY, Baik SK, Cho YZ
and Kwon SO: Effect of bone marrow-derived mesenchymal stem cells
on hepatic fibrosis in a thioacetamide-induced cirrhotic rat model.
BMC Gastroenterol. 14:1982014. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Zhao MM, Cui JZ, Li R, Du LJ, Tian YX, Kan
Q, Zhang J and Gao JL: Effects of bone mesenchymal stem cell
transplantation on silicosis fibrosis in rats. Chin J Pathophysiol.
28:2205–2210. 2012.
|
