Journal Articles
Review
Galectin-3 as a novel biomarker for disease diagnosis and a target for therapy (Review)
Rui Dong, Min Zhang, Qunying Hu, Shan Zheng, Andrew Soh, Yijie Zheng, Hui Yuan
Pages: 599-614 Published online on: 05 December 2017
Review
Mitochondria-mediated damage to dopaminergic neurons in Parkinson's disease (Review)
Xiao‑Liang Liu, Ying‑Di Wang, Xiu‑Ming Yu, Da‑Wei Li, Guang‑Ren Li
Pages: 615-623 Published online on: 16 November 2017
Review
Necroptosis: A novel manner of cell death, associated with stroke (Review)
Chenglin Liu, Kai Zhang, Haitao Shen, Xiyang Yao, Qing Sun, Gang Chen
Pages: 624-630 Published online on: 22 November 2017
Review
The role and mechanism of β‑arrestins in cancer invasion and metastasis (Review)
Qing Song, Qing Ji, Qi Li
Pages: 631-639 Published online on: 27 November 2017
Article
A common African variant of human connexin 37 is associated with Caucasian primary ovarian insufficiency and has a deleterious effect in vitro
Anne Bachelot, Jerome Gilleron, Geri Meduri, Mihelai Guberto, Jerome Dulon, Sylviane Boucherie, Philippe Touraine, Micheline Misrahi
Pages: 640-648 Published online on: 16 November 2017
Article
Naringenin induces laxative effects by upregulating the expression levels of c-Kit and SCF, as well as those of aquaporin 3 in mice with loperamide-induced constipation
Jianqiao Yin, Yichao Liang, Dalu Wang, Zhaopeng Yan, Hongzhuan Yin, Di Wu, Qi Su
Pages: 649-658 Published online on: 01 December 2017
Article
Therapeutic effects of conditioned medium from bone marrow-derived mesenchymal stem cells on epithelial-mesenchymal transition in A549 cells
Xin Wang, Jun-Ling Gao, Man-Man Zhao, Hui-Xing Zhu, Yan-Xia Tian, Ran Li, Xiao-Hua Jiang, Lei Yu, Jing-Rui Tian, Jian-Zhong Cui
Pages: 659-668 Published online on: 24 November 2017
Article
In vitro cell behaviors of bone mesenchymal stem cells derived from normal and postmenopausal osteoporotic rats
Qian Liu, Xiaoxia Zhang, Yang Jiao, Xin Liu, Yirong Wang, Song-Lun Li, Wei Zhang, Fa-Ming Chen, Yin Ding, Chuan Jiang, Zuolin Jin
Pages: 669-678 Published online on: 22 November 2017
Article
Use of methylation profiling to identify significant differentially methylated genes in bone marrow mesenchymal stromal cells from acute myeloid leukemia
Jing Huang, Zhi Liu, Yufan Sun, Qi Zhong, Li Xu, Ruimin Ou, Cheng Li, Rui Chen, Mengdong Yao, Qing Zhang, Shuang Liu
Pages: 679-686 Published online on: 17 November 2017
Article
Stromal-epithelial lactate shuttle induced by tumor‑derived interleukin‑1β promotes cell proliferation in oral squamous cell carcinoma
Jie Wu, Yun Hong, Tong Wu, Juan Wang, Xiaobing Chen, Zhi Wang, Bin Cheng, Juan Xia
Pages: 687-696 Published online on: 17 November 2017
Article
Interaction of iPSC-derived neural stem cells on poly(L-lactic acid) nanofibrous scaffolds for possible use in neural tissue engineering
Chengkai Lin, Chang Liu, Liangming Zhang, Zhi Huang, Peipei Zhao, Ruiqiang Chen, Mao Pang, Zhenxiang Chen, Liumin He, Chunxiao Luo, Limin Rong, Bin Liu
Pages: 697-708 Published online on: 30 November 2017
Article
Neurochemical changes in the hippocampus and prefrontal cortex associated with electroacupuncture for learning and memory impairment
Jian He, Congkuai Zhao, Weilin Liu, Jia Huang, Shengxiang Liang, Lidian Chen, Jing Tao
Pages: 709-716 Published online on: 24 November 2017
Article
A type 2 diabetes-associated SNP in KCNQ1 (rs163184) modulates the binding activity of the locus for Sp3 and Lsd1/Kdm1a, potentially affecting CDKN1C expression
Masaki Hiramoto, Haruhide Udagawa, Naoko Ishibashi, Eri Takahashi, Yasushi Kaburagi, Keisuke Miyazawa, Nobuaki Funahashi, Takao Nammo, Kazuki Yasuda
Pages: 717-728 Published online on: 20 November 2017
Article
Platelet-rich plasma inhibits RANKL-induced osteoclast differentiation through activation of Wnt pathway during bone remodeling
Dongyue Wang, Yajuan Weng, Shuyu Guo, Yuxin Zhang, Tingting Zhou, Mengnan Zhang, Lin Wang, Junqing Ma
Pages: 729-738 Published online on: 16 November 2017
Article
Geraniin protects bone marrow‑derived mesenchymal stem cells against hydrogen peroxide‑induced cellular oxidative stress in vitro
Dan Huang, Li Yin, Xinxin Liu, Bo Lv, Zulong Xie, Xuedong Wang, Bo Yu, Yao Zhang
Pages: 739-748 Published online on: 21 November 2017
Article
Effects of kartogenin on the attenuated nucleus pulposus cell degeneration of intervertebral discs induced by interleukin-1β and tumor necrosis factor-α
Yao Huang, Tao Jiang, Jian Chen, Guo-Yong Yin, Jin Fan
Pages: 749-756 Published online on: 24 November 2017
Article
Der f1 induces pyroptosis in human bronchial epithelia via the NLRP3 inflammasome
Ying‑Ming Tsai, Kuo‑Hwa Chiang, Jen‑Yu Hung, Wei‑An Chang, Hui‑Ping Lin, Jiunn‑Min Shieh, Inn‑Wen Chong, Ya‑Ling Hsu
Pages: 757-764 Published online on: 05 December 2017
Article
Chlorogenic acid attenuates hydrogen peroxide‑induced oxidative stress in lens epithelial cells
Jike Song, Dadong Guo, Hongsheng Bi
Pages: 765-772 Published online on: 01 December 2017
Article
Clinical and next-generation sequencing findings in a Chinese family exhibiting severe familial exudative vitreoretinopathy
Ying Lin, Hongbin Gao, Chuan Chen, Yi Zhu, Tao Li, Bingqian Liu, Chenghong Ma, Hongye Jiang, Yonghao Li, Ying Huang, Qingxiu Wu, Haichun Li, Xiaoling Liang, Chenjin Jin, Jianhua Ye, Xinhua Huang, Lin Lu
Pages: 773-782 Published online on: 05 December 2017
Article
Comparative analysis of human embryonic stem cell‑derived neural stem cells as an in vitro human model
Jung‑Hwa Oh, Cho‑Rok Jung, Mi‑Ok Lee, Janghwan Kim, Mi‑Young Son
Pages: 783-790 Published online on: 30 November 2017
Article
Human amniotic epithelial cells regulate osteoblast differentiation through the secretion of TGFβ1 and microRNA-34a-5p
Guiling Wang, Feng Zhao, Di Yang, Jing Wang, Lihong Qiu, Xining Pang
Pages: 791-799 Published online on: 17 November 2017
Article
Autophagy relieves the function inhibition and apoptosis‑promoting effects on osteoblast induced by glucocorticoid
Yudi Han, Lihai Zhang, Yaling Xing, Licheng Zhang, Xiaojuan Chen, Peifu Tang, Zhongbin Chen
Pages: 800-808 Published online on: 17 November 2017
Article
TAT‑fused IP3R‑derived peptide enhances cisplatin sensitivity of ovarian cancer cells by increasing ER Ca2+ release
Qi Xie, Ye Xu, Weinan Gao, Yong Zhang, Jing Su, Yanan Liu, Yuting Guo, Minghan Dou, Kebang Hu, Liankun Sun
Pages: 809-817 Published online on: 16 November 2017
Article
Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma
Nan Yang, Han Zhang, Xuxu Cai, Yunxiao Shang
Pages: 818-828 Published online on: 28 November 2017
Article
Erythropoietin induces the osteogenesis of periodontal mesenchymal stem cells from healthy and periodontitis sources via activation of the p38 MAPK pathway
Liying Wang, Fan Wu, Yang Song, Yinzhong Duan, Zoulin Jin
Pages: 829-835 Published online on: 28 November 2017
Article
Clinical significance of interleukin‑6 and inducible nitric oxide synthase in ketamine‑induced cystitis
Chi‑Jung Huang, Fa‑Kung Lee, Shao‑Kuan Chen, Chih‑Cheng Chien, Sheng‑Tang Wu, Yen‑Chieh Wang
Pages: 836-844 Published online on: 17 November 2017
Article
Transcription factor TBX18 promotes adult rat bone mesenchymal stem cell differentiation to biological pacemaker cells
Yanjun Li, Mei Yang, Gege Zhang, Le Li, Bingjie Ye, Congxin Huang, Yanhong Tang
Pages: 845-851 Published online on: 16 November 2017
Article
Chronic prenatal hypoxia impairs cochlear development, a mechanism involving connexin26 expression and promoter methylation
Jingcang Lin, Huang Huang, Guorong Lv, Xiangyang Xu, Wendong Lin, Xianyan Xu, Jing Cheng, Ming Zheng
Pages: 852-858 Published online on: 01 December 2017
Article
The potential inhibitory effects of miR‑19b on vulnerable plaque formation via the suppression of STAT3 transcriptional activity
Sufang Li, Qiang Geng, Hong Chen, Jing Zhang, Chengfu Cao, Feng Zhang, Junxian Song, Chuanfen Liu, Wenqing Liang
Pages: 859-867 Published online on: 17 November 2017
Article
Aryl hydrocarbon receptor inhibits inflammation in DSS‑induced colitis via the MK2/p‑MK2/TTP pathway
Qimeng Wang, Kunqiu Yang, Bin Han, Baifa Sheng, Jiuheng Yin, Aimin Pu, Liangzi Li, Lihua Sun, Min Yu, Yuan Qiu, Weidong Xiao, Hua Yang
Pages: 868-876 Published online on: 17 November 2017
Article
Coordinated microRNA/mRNA expression profiles reveal a putative mechanism of corneal epithelial cell transdifferentiation from skin epidermal stem cells
Yanjie Guo, Xiya Ma, Weini Wu, Mingyan Shi, Junlong Ma, Yaping Zhang, Erkang Zhao, Xueyi Yang
Pages: 877-887 Published online on: 01 December 2017
Article
Anti‑inflammatory effect of quercetin and galangin in LPS‑stimulated RAW264.7 macrophages and DNCB‑induced atopic dermatitis animal models
Hae Nim Lee, Seong Ah Shin, Gang Sik Choo, Hyeong Jin Kim, Young Seok Park, Byeong Soo Kim, Sang Ki Kim, Sung Dae Cho, Jeong Seok Nam, Chang Sun Choi, Jeong Hwan Che, Byung Kwon Park, Ji Youn Jung
Pages: 888-898 Published online on: 29 November 2017
Article
Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor‑κB pathway and inhibition of inflammasome activation in alcoholic hepatitis
Jiajun Li, Cheng Yang, Shu Zhang, Shu Liu, Luole Zhao, Huan Luo, Yatang Chen, Wenxiang Huang
Pages: 899-907 Published online on: 29 November 2017
Article
Pentosan polysulfate ameliorates apoptosis and inflammation by suppressing activation of the p38 MAPK pathway in high glucose‑treated HK‑2 cells
Ping Chen, Yang Yuan, Tianying Zhang, Bo Xu, Qing Gao, Tianjun Guan
Pages: 908-914 Published online on: 27 November 2017
Article
Molecular expression of multiple Nav1.5 splice variants in the frontal lobe of the human brain
Jun Wang, Shao‑Wu Ou, Zhi‑Yong Zhang, Bo Qiu, Yun‑Jie Wang
Pages: 915-923 Published online on: 24 November 2017
Article
Anti-obesity effects of pectinase and cellulase enzyme‑treated Ecklonia cava extract in high‑fat diet‑fed C57BL/6N mice
In‑Hye Kim, Jung‑Wook Choi, Min‑Kyeong Lee, Chang‑Ju Kwon, Taek‑Jeong Nam
Pages: 924-934 Published online on: 28 November 2017
Article
Hepatic recruitment of CD11b+Ly6C+ inflammatory monocytes promotes hepatic ischemia/reperfusion injury
Peng Song, Junbin Zhang, Yunwei Zhang, Zhiping Shu, Peng Xu, Long He, Chao Yang, Jinxiang Zhang, Hui Wang, Yiqing Li, Qin Li
Pages: 935-945 Published online on: 08 December 2017
Article
CD90 promotes cell migration, viability and sphere‑forming ability of hepatocellular carcinoma cells
Ketao Zhang, Siyao Che, Zheng Su, Shangyou Zheng, Huayao Zhang, Shanglin Yang, Wenda Li, Jianping Liu
Pages: 946-954 Published online on: 08 December 2017
Article
Melatonin exerts an inhibitory effect on insulin gene transcription via MTNR1B and the downstream Raf‑1/ERK signaling pathway
Yanliang Li, Huihui Wu, Naijia Liu, Xinyi Cao, Zhen Yang, Bin Lu, Renming Hu, Xuanchun Wang, Jie Wen
Pages: 955-961 Published online on: 01 December 2017
Article
Effective component of Salvia miltiorrhiza in promoting cardiomyogenic differentiation of human placenta‑derived mesenchymal stem cells
Kun Li, Jieqiong Song, Qian Zhao, Bo Wang, Yunli Zhang, Xuezhe Wang, Tiantian Tang, Shizheng Li
Pages: 962-968 Published online on: 28 November 2017
Article
Stromal cell‑derived factor‑1 induces matrix metalloproteinase expression in human endplate chondrocytes, cartilage endplate degradation in explant culture, and the amelioration of nucleus pulposus degeneration in vivo
Hua Zhang, Ting Zhu, Li Zhang, Qionghua Wu
Pages: 969-976 Published online on: 22 November 2017
Article
Different roles of Akt and mechanistic target of rapamycin in serum‑dependent chondroprotection of human osteoarthritic chondrocytes
Tongen Zhang, Jijie Liu, Xinpeng Zheng, Bing Zhang, Chun Xia
Pages: 977-984 Published online on: 24 November 2017
Article
Mechanism of endogenous digitalis-like factor‑induced vascular endothelial cell damage in patients with severe preeclampsia
Mei Peng, Mengyuan Yang, Yiling Ding, Ling Yu, Yali Deng, Weisi Lai, Yun Hu
Pages: 985-994 Published online on: 11 December 2017
Article
Sevoflurane inhibits the malignant potential of head and neck squamous cell carcinoma via activating the hypoxia‑inducible factor-1α signaling pathway in vitro
Yaqiong Yang, Rong Hu, Jia Yan, Zhifeng Chen, Yi Lu, Jue Jiang, Hong Jiang
Pages: 995-1002 Published online on: 04 December 2017
Article
Periostin has a protective role in melatonin‑induced cell apoptosis by inhibiting the eIF2α‑ATF4 pathway in human osteoblasts
Xiaotong Meng, Yue Zhu, Lin Tao, Sichao Zhao, Shui Qiu
Pages: 1003-1012 Published online on: 30 November 2017
Article
Co-expression network analysis of lncRNAs and mRNAs in OPTN-silenced cells
Lin Jin, Yuanyuan Li, Xinrong Zhou, Huiping Yuan
Pages: 1013-1020 Published online on: 06 December 2017
Article
MicroRNA‑30a‑5p suppresses tumor cell proliferation of human renal cancer via the MTDH/PTEN/AKT pathway
Jianmin Li, Changying Li, Hongjie Li, Ting Zhang, Xiaodong Hao, Jiwu Chang, Yong Xu
Pages: 1021-1029 Published online on: 17 November 2017
Article
MicroRNA-21 promotes the progression of peritoneal fibrosis through the activation of the TGF-?/Smad signaling pathway: An in vitro and in vivo study Retraction in /10.3892/ijmm.2020.4510
Ya-Li Ma, Fang Chen, Su-Xia Yang, Bao-Ping Chen, Jun Shi
Pages: 1030-1038 Published online on: 17 November 2017
Article
Icariin possesses chondroprotective efficacy in a rat model of dexamethasone-induced cartilage injury through the activation of miR-206 targeting of cathepsin K
Ning Liu, Tao Zhang, Bo-Ran Cao, Fei-Yu Luan, Rui-Xuan Liu, Hao-Rong Yin, Wen-Bo Wang
Pages: 1039-1047 Published online on: 27 November 2017
Article
Investigation of the pro-apoptotic effects of arbutin and its acetylated derivative on murine melanoma cells
Liyan Jiang, Di Wang, Yongfeng Zhang, Junyang Li, Zhiping Wu, Zhi Wang
Pages: 1048-1054 Published online on: 16 November 2017
Article
Role of inhibitor of growth 4 in the suppression of human melanoma cells through the Fas/FasL-mediated apoptosis pathway
Limin Cai, Haiyan Li, Cui Chen, Xue Cheng, Yu Wang, Jing Liu, Yongchen Wang, Lijun Hao
Pages: 1055-1061 Published online on: 20 November 2017
Article
Macrophage migration inhibitory factor promotes Warburg effect via activation of the NF‑κB/HIF‑1α pathway in lung cancer
Jun Li, Junhua Zhang, Fengjiao Xie, Jiangzhou Peng, Xu Wu
Pages: 1062-1068 Published online on: 22 November 2017
Article
High-resolution metabolomics determines the mode of onset of type 2 diabetes in a 3-year prospective cohort study
Yeseung Lee, Aryo Dimas Pamungkas, Carl Angelo D. Medriano, Jinsung Park, Seri Hong, Sun Ha Jee, Youngja H. Park
Pages: 1069-1077 Published online on: 21 November 2017
Article
Astragaloside IV prevents kidney injury caused by iatrogenic hyperinsulinemia in a streptozotocin‑induced diabetic rat model
Ke‑Qiang He, Wei‑Zu Li, Xiao‑Qing Chai, Yan‑Yan Yin, Yan Jiang, Wei‑Ping Li
Pages: 1078-1088 Published online on: 17 November 2017
Article
Diosgenin prevents high-fat diet-induced rat non-alcoholic fatty liver disease through the AMPK and LXR signaling pathways
Silu Cheng, Shufang Liang, Qun Liu, Zhengting Deng, Yuanhui Zhang, Juan Du, Ya'ni Zhang, Shu Li, Binbin Cheng, Changquan Ling
Pages: 1089-1095 Published online on: 28 November 2017
Article
Role of the cofilin 2 gene in regulating the myosin heavy chain genes in mouse myoblast C2C12 cells
Hongyan Zhu, Huixin Yang, Song Zhao, Junfeng Zhang, Dan Liu, Yumin Tian, Zhiyi Shen, Yuhong Su
Pages: 1096-1102 Published online on: 17 November 2017
Article
Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-κB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264.7 macrophages
Hyung-Wook Choi, Pyung-Gyun Shin, Ji-Hyun Lee, Woo-Suk Choi, Min-Jae Kang, Won-Sik Kong, Min-Ji Oh, Yong-Bae Seo, Gun-Do Kim
Pages: 1103-1109 Published online on: 05 December 2017
Article
Periodontal ligament‑associated protein‑1 delays rat periodontal bone defect repair by regulating osteogenic differentiation of bone marrow stromal cells and osteoclast activation
Xijiao Yu, Shuang Liu, Wei Wang, Shu Li
Pages: 1110-1118 Published online on: 06 December 2017
Article
Role of the c-Jun N-terminal kinase signaling pathway in the activation of trypsinogen in rat pancreatic acinar cells
Zhengpeng Yang, Weiguang Yang, Ming Lu, Zhituo Li, Xin Qiao, Bei Sun, Weihui Zhang, Dongbo Xue
Pages: 1119-1126 Published online on: 17 November 2017
Article
Macrophage migration inhibitory factor rescues mesenchymal stem cells from doxorubicin-induced senescence though the PI3K-Akt signaling pathway
Wenzheng Xia, Meng Hou
Pages: 1127-1137 Published online on: 23 November 2017
Article
Quercetin inhibits okadaic acid-induced tau protein hyperphosphorylation through the Ca2+‑calpain‑p25‑CDK5 pathway in HT22 cells
Xiu‑Yin Shen, Tao Luo, Sheng Li, Ou‑Yang Ting, Feng He, Jie Xu, Hua‑Qiao Wang
Pages: 1138-1146 Published online on: 22 November 2017
Article