β-glucans and cholesterol (Review)
- Authors:
- Petr Sima
- Luca Vannucci
- Vaclav Vetvicka
-
Affiliations: Laboratory of Immunotherapy, Institute of Microbiology of The Czech Academy of Sciences, 14220 Prague 4, Czech Republic, Department of Pathology, University of Louisville, Louisville, KY 40202, USA - Published online on: January 22, 2018 https://doi.org/10.3892/ijmm.2018.3411
- Pages: 1799-1808
-
Copyright: © Sima et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
This article is mentioned in:
Abstract
 |
 |
|
World Health Organization: Obesity and overweight fact sheet. 2017 | |
|
World Health Organization: Obesity and overweight fact sheet. 2016 | |
|
CDC, National Center for Chronic Disease Prevention and Health Promotion and Division for Heart Disease and Stroke Prevention: Heart Disease Facts and Statistics. CDC; | |
|
Murray CJ and Lopez AD: Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. Lancet. 349:1498–1504. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
Oreopoulos A, Padwal R, Kalantar-Zadeh K, Fonarow GC, Norris CM and McAlister FA: Body mass index and mortality in heart failure: A meta-analysis. Am Heart J. 156:13–22. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Clark JM and Brancati FL: The challenge of obesity-related chronic diseases. J Gen Intern Med. 15:828–829. 2000. View Article : Google Scholar : PubMed/NCBI | |
|
Oreopoulos A, Ezekowitz JA, McAlister FA, Kalantar-Zadeh K, Fonarow GC, Norris CM, Johnson JA and Padwal RS: Association between direct measures of body composition and prognostic factors in chronic heart failure. Mayo Clin Proc. 85:609–617. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Bose KS, Gupta SK and Vyas P: Adipocytokine levels in genetically high risk for type 2 diabetes in the Indian population: A cross-sectional study. Exp Diabetes Res. 2012:3865242012. View Article : Google Scholar : PubMed/NCBI | |
|
Olson NC, Callas PW, Hanley AJ, Festa A, Haffner SM, Wagenknecht LE and Tracy RP: Circulating levels of TNF-α are associated with impaired glucose tolerance, increased insulin resistance, and ethnicity: The insulin resistance atherosclerosis study. J Clin Endocrinol Metab. 97:1032–1040. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Libby P, Ridker PM and Maseri A: Inflammation and atherosclerosis. Circulation. 105:1135–1143. 2002. View Article : Google Scholar : PubMed/NCBI | |
|
Emanuela F, Grazia M, Marco de R, Maria Paola L, Giorgio F and Marco B: Inflammation as a link between obesity and metabolic syndrome. J Nutr Metab. 2012:4763802012. View Article : Google Scholar : PubMed/NCBI | |
|
Harland JI: Food combinations for cholesterol lowering. Nutr Res Rev. 25:249–266. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Johnston TP, Korolenko TA, Pirro M and Sahebkar A: Preventing cardiovascular heart disease: Promising nutraceutical and non-nutraceutical treatments for cholesterol management. Pharmacol Res. 120:219–225. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Chatzizisis YS, Koskinas KC, Misirli G, Vaklavas C, Hatzitolios A and Giannoglou GD: Risk factors and drug interactions predisposing to statin-induced myopathy: Implications for risk assessment, prevention and treatment. Drug Saf. 33:171–187. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Camerino GM, Musumeci O, Conte E, Musaraj K, Fonzino A, Barca E, Marino M, Rodolico C, Tricarico D, Camerino C, et al: Risk of myopathy in patients in therapy with statins: Identification of biological markers in a pilot study. Front Pharmacol. 8:5002017. View Article : Google Scholar : PubMed/NCBI | |
|
Caparros-Martin JA, Lareu RR, Ramsay JP, Peplies J, Reen FJ, Headlam HA, Ward NC, Croft KD, Newsholme P, Hughes JD, et al: Statin therapy causes gut dysbiosis in mice through a PXR-dependent mechanism. Microbiome. 5:952017. View Article : Google Scholar : PubMed/NCBI | |
|
Verhaegh BP, de Vries F, Masclee AA, Keshavarzian A, de Boer A, Souverein PC, Pierik MJ and Jonkers DM: High risk of drug-induced microscopic colitis with concomitant use of NSAIDs and proton pump inhibitors. Aliment Pharmacol Ther. 43:1004–1013. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
O'Keefe SJ: Diet, microorganisms and their metabolites, and colon cancer. Nat Rev Gastroenterol Hepatol. 13:691–706. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Peters U, Sinha R, Chatterjee N, Subar AF, Ziegler RG, Kulldorff M, Bresalier R, Weissfeld JL, Flood A, Schatzkin A, et al: Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme. Lancet. 361:1491–1495. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Mao QQ, Lin YW, Chen H, Qin J, Zheng XY, Xu X and Xie LP: Dietary fiber intake is inversely associated with risk of pancreatic cancer: A meta-analysis. Asia Pac J Clin Nutr. 26:89–96. 2017.PubMed/NCBI | |
|
Ohira H, Tsutsui W and Fujioka Y: Are short chain fatty acids in hut microbiota defensive players for inflammation and atherosclerosis. J Atheroscler Thromb. 24:660–672. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Hernandez-Rodas MC, Valenzuela R and Videla LA: Relevant aspects of nutritional and dietary interventions in non-alcoholic fatty liver disease. Int J Mol Sci. 16:25168–25198. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Burton-Freeman B, Liyanage D, Rahman S and Edirisinghe I: Ratios of soluble and insoluble dietary fibers on satiety and energy intake in overweight pre- and postmenopausal women. Nutr Healthy Aging. 4:157–168. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Adam CL, Thomson LM, Williams PA and Ross AW: Soluble fermentable dietary fibre (Pectin) decreases caloric intake, adiposity and lipidaemia in high-fat diet-induced obese rats. PLoS One. 10:e01403922015. View Article : Google Scholar : PubMed/NCBI | |
|
Torcello-Gómez A, Fernández Fraguas C, Ridout MJ, Woodward NC, Wilde PJ and Foster TJ: Effect of substituent pattern and molecular weight of cellulose ethers on interactions with different bile salts. Food Funct. 6:730–739. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Meneses ME, Martinez-Carrera D, Torres N, Sánchez-Tapia M, Aguilar-López M, Morales P, Sobal M, Bernabé T, Escudero H, Granados-Portillo O and Tovar AR: Hypocholesterolemic properties and prebiotic effects of Mexican Ganoderma lucidum in C57BL/6 mice. PLoS One. 11:e01596312016. View Article : Google Scholar : PubMed/NCBI | |
|
Hung TV and Suzuki T: Dietary fermentable fiber reduces intestinal barrier defects and inflammation in colitic mice. J Nutr. 146:1970–1979. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Zhong Y, Marungruang N, Fak F and Nyman M: Effects of two whole-grain barley varieties on caecal SCFA, gut microbiota and plasma inflammatory markers in rats consuming low- and high-fat diets. Br J Nutr. 113:1558–1570. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Luo Y, Zhang L, Li H, Smidt H, Wright AG, Zhang K, Ding X, Zeng Q, Bai S, Wang J, et al: Different types of dietary fibers trigger specific alterations in composition and predicted functions of colonic bacterial communities in BALB/c mice. Front Microbiol. 8:9662017. View Article : Google Scholar : PubMed/NCBI | |
|
Winglee K and Fodor AA: Intrinsic association between diet and the gut microbiome: Current evidence. Nutr Diet Suppl. 7:69–76. 2015.PubMed/NCBI | |
|
Jakobsdottir G, Xu J, Molin G, Ahrné S and Nyman M: High-fat diet reduces the formation of butyrate, but increases succinate, inflammation, liver fat and cholesterol in rats, while dietary fibre counteracts these effects. PLoS One. 8:e804762013. View Article : Google Scholar : PubMed/NCBI | |
|
Vannucci L, Krizan J, Sima P, Stakheev D, Caja F, Rajsiglova L, Horak V and Saieh M: Immunostimulatory properties and anti-tumor activities of glucans (Review). Int J Oncol. 43:357–364. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Chanput W, Reitsma M, Kleinjans L, Mes JJ, Savelkoul HF and Wichers HJ: β-Glucans are involved in immune-modulation of THP-1 macrophages. Mol Nutr Food Res. 56:822–833. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Ho HV, Sievenpiper JL, Zurbau A, Blanco Mejia S, Jovanovski E, Au-Yeung F, Jenkins AL and Vuksan V: The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: A systematic review and meta-analysis of randomized-controlled trials. Br J Nutr. 116:1369–1382. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Caz V, Gil-Ramirez A, Largo C, Tabernero M, Santamaría M, Martín-Hernández R, Marín FR, Reglero G and Soler-Rivas C: Modulation of cholesterol-related gene expression by dietary fiber fractions from edible mushrooms. J Agric Food Chem. 63:7371–7380. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Barsanti L, Passarelli V, Evangelista V, Frassanito AM and Gualtieri P: Chemistry, physico-chemistry and applications linked to biological activities of β-glucans. Nat Prod Rep. 28:457–466. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Anderson JW, Baird P, Davis RH Jr, Ferreri S, Knudtson M, Koraym A, Waters V and Williams CL: Health benefits of dietary fiber. Nutr Rev. 67:188–205. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Van Horn L, McCoin M, Kris-Etherton PM, Burke F, Carson JA, Champagne CM, Karmally W and Sikand G: The evidence for dietary prevention and treatment of cardiovascular disease. J Am Diet Assoc. 108:287–331. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Vetvicka V and Vetvickova J: Effects of yeast-derived beta-glucans on blood cholesterol and macrophage functionality. J Immunotoxicol. 6:30–35. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
de Groot A, Luyken R and Pikaar NA: Cholesterol-lowering effect of rolled oats. Lancet. 2:303–304. 1963. View Article : Google Scholar : PubMed/NCBI | |
|
Czop JK: The role of beta-glucan receptors on blood and tissue leukocytes in phagocytosis and metabolic activation. Pathol Immunopathol Res. 5:286–296. 1986. View Article : Google Scholar : PubMed/NCBI | |
|
Estrada A, Yun CH, Van Kessel A, Li B, Hauta S and Laarveld B: Immunomodulatory activities of oat beta-glucan in vitro and in vivo. Microbiol Immunol. 41:991–998. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
Torrence PF: Biological response modifiers: New approaches to disease intervention. Academic Press; Orlando: pp. 3971985 | |
|
Novak M and Vetvicka V: Beta-glucans, history, and the present: Immunomodulatory aspects and mechanisms of action. J Immunotoxicol. 5:47–57. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Vetvicka V and Vetvickova J: β1,3-Glucan: Silver bullet or hot air. Open Glycoscience. 3:1–6. 2010. | |
|
Vetvicka V and Vetvickova J: Comparison of immunological effects of commercially available β-glucans: Part III. Int J Clin Pathol. 2:2006. View Article : Google Scholar | |
|
Würsch P and Pi-Sunyer FX: The role of viscous soluble fiber in the metabolic control of diabetes. A review with special emphasis on cereals rich in beta-glucan. Diabetes Care. 20:1774–1780. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
Mosikanon K, Arthan D, Kettawan A, Tungtrongchitr R and Prangthip P: Yeast β-glucan modulates inflammation and waist circumference in overweight and obese subjects. J Diet Suppl. 14:173–185. 2017. View Article : Google Scholar | |
|
Browder W, Williams D, Lucore P, Pretus H, Jones E and McNamee R: Effect of enhanced macrophage function on early wound healing. Surgery. 104:224–230. 1988.PubMed/NCBI | |
|
Vetvicka V and Vetvickova J: Anti-stress action of an orally-given combination of resveratrol, β-glucan, and vitamin C. Molecules. 19:13724–13734. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Vetvicka V and Vetvickova J: β-glucan attenuates chronic fatigue syndrome in murine model. J Nat Sci. 1:e1122015. | |
|
Sima P, Vannucci L and Vetvicka V: Glucans and cancer: Historical perspective. Cancer Translational Med. 1:209–214. 2015. View Article : Google Scholar | |
|
Barbieri A, Quagliariello V, Del Vecchio V, Falco M, Luciano A, Amruthraj NJ, Nasti G, Ottaiano A, Berretta M, Iaffaioli RV and Arra C: Anticancer and anti-inflammatory properties of gano-derma lucidum extract effects on melanoma and triple-negative breast cancer treatment. Nutrients. 9:pii:E2102017. View Article : Google Scholar | |
|
Richter J, Kral V, Svozil V, Rajnohova DL, Pohorska JI and Vetvicka V: Effects of transfer point glucan #300 supplementation on children exposed to passive smoking-placebo-driven double-blind clinical trials. J Nutr Health. 1:1052014. | |
|
Vetvicka V, Richter J, Svozil V, Rajnohová Dobiášová L and Král V: Placebo-driven clinical trials of yeast-derived β-(1-3) glucan in children with chronic respiratory problems. Ann Transl Med. 1:262013. | |
|
Brown GD and Gordon S: Immune recognition. A new receptor for beta-glucans. Nature. 413:36–37. 2001. View Article : Google Scholar : PubMed/NCBI | |
|
Stambach NS and Taylor ME: Characterization of carbohydrate recognition by langerin, a C-type lectin of Langerhans cells. Glycobiology. 13:401–410. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Allendorf DJ, Ostroff GR, BAran JT, et al: Oral WGP beta glucan treatment accelerates myeloid recovery and survival after irradiation wxposure. BTR 2003: Unified Science & Technology for Reducing Biological Threats & Counterin Terrorism Albuquesrque: University of New Mexico; pp. 104–113. 2003 | |
|
Ross GD and Vĕtvicka V: CR3 (CD11b. CD18): A phagocyte and NK cell membrane receptor with multiple ligand specificities and functions. Cell Exp Immunol. 92:181–184. 1993. View Article : Google Scholar | |
|
Xia Y, Vetvicka V, Yan J, Hanikyrová M, Mayadas T and Ross GD: The beta-glucan-binding lectin site of mouse CR3 (CD11b/CD18) and its function in generating a primed state of the receptor that mediates cytotoxic activation in response to iC3b-opsonized target cells. J Immunol. 162:2281–2290. 1999.PubMed/NCBI | |
|
Legentil L, Paris F, Ballet C, Trouvelot S, Daire X, Vetvicka V and Ferrières V: Molecular interactions of β-(1→>3)-glucans with their receptors. Molecules. 20:9745–9766. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Williams DL, Ha T, Li C, Laffan J, Kalbfleisch J and Browder W: Inhibition of LPS-induced NFkappaB activation by a glucan ligand involves down-regulation of IKKbeta kinase activity and altered phosphorylation and degradation of IkappaBalpha. Shock. 13:446–452. 2000. View Article : Google Scholar : PubMed/NCBI | |
|
Rogers NC, Slack EC, Edwards AD, Nolte MA, Schulz O, Schweighoffer E, Williams DL, Gordon S, Tybulewicz VL, Brown GD and Reis e Sousa C: Syk-dependent cytokine induction by Dectin-1 reveals a novel pattern recognition pathway for C type lectins. Immunity. 22:507–517. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Elcombe SE, Naqvi S, Van Den Bosch MW, MacKenzie KF, Cianfanelli F, Brown GD and Arthur JS: Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers. PLoS One. 8:e600862013. View Article : Google Scholar : PubMed/NCBI | |
|
Větvička V: (Beta)-glucans as natural biological response modifiers. Nova Science Publishers Inc; New York: 2013 | |
|
Orth M and Bellosta S: Cholesterol: Its regulation and role in central nervous system disorders. Cholesterol. 2012:2925982012. View Article : Google Scholar : PubMed/NCBI | |
|
Li T and Chiang JY: Regulation of bile acid and cholesterol metabolism by PPARs. PPAR Res. 2009:5017392009. View Article : Google Scholar : PubMed/NCBI | |
|
Worthmann A, John C, Rühlemann MC, Baguhl M, Heinsen FA, Schaltenberg N, Heine M, Schlein C, Evangelakos I, Mineo C, et al: Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis. Nat Med. 23:839–849. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Li T and Chiang JY: Bile acids as metabolic regulators. Curr Opin Gastroenterol. 31:159–165. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Brown MS and Goldstein JL: How LDL receptors influence cholesterol and atherosclerosis. Sci Am. 251:58–66. 1984. View Article : Google Scholar : PubMed/NCBI | |
|
Russell DW: The enzymes, regulation, and genetics of bile acid synthesis. Annu Rev Biochem. 72:137–174. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Kuipers F, Bloks VW and Groen AK: Beyond intestinal soap-bile acids in metabolic control. Nat Rev Endocrinol. 10:488–498. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Gibbons GF, Wiggins D, Brown AM and Hebbachi AM: Synthesis and function of hepatic very-low-density-lipoprotein. Biochem Soc Trans. 32:59–64. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Davidson WS and Hilliard GM: The spatial organization of apolipoprotein A-I on the edge of discoidal high density lipo-protein particles. J Biol Chem. 278:27199–27207. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
de Oliveira Alvim R, Mourao-Junior CA, Magalhaes GL, de Oliveira CM, Krieger JE, Mill JG and Pereira AC: Non-HDL cholesterol is a good predictor of the risk of incfeased arterial stiffness in postmenopausal women in an urban Brazilian population. Clinics (Sao Paulo). 72:106–110. 2017. View Article : Google Scholar | |
|
Gordon DJ, Probstfield JL, Garrison RJ, Neaton JD, Castelli WP, Knoke JD, Jacobs DR Jr, Bangdiwala S and Tyroler HA: High-density lipoprotein cholesterol and cardiovascular disease. Four prospective American studies. Circulation. 79:8–15. 1989. View Article : Google Scholar : PubMed/NCBI | |
|
Srinivasan SR, Myers L and Berenson GS: Distribution and correlates of non-high-density lipoprotein cholesterol in children: The Bogalusa heart study. Pediatrics. 110:e292002. View Article : Google Scholar : PubMed/NCBI | |
|
Hoenig MR: Implications of the obesity epidemic for lipid-lowering therapy: Non-HDL cholesterol should replace LDL cholesterol as the primary therapeutic target. Vasc Health Risk Manag. 4:143–156. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
The National Cholesterol Education Program. https://www.nhlbi.nih.gov/files/docs/guidelines/atglance.pdf. | |
|
Masson D, Koseki M, Ishibashi M, Larson CJ, Miller SG, King BD and Tall AR: Increased HDL cholesterol and apoA-I in humans and mice treated with a novel SR-BI inhibitor. Arterioscler Thromb Vasc Biol. 29:2054–2060. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
White CR, Garber DW and Anantharamaiah GM: Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: A review. J Lipid Res. 55:2007–2021. 2014. View Article : Google Scholar : PubMed/NCBI | |
|
Parathasarathy S, Raghavamenon A, Garelnabi MO and Santanam N: Oxidized low-density lipoprotein. Methods Mol Biol. 610:403–417. 2010. View Article : Google Scholar | |
|
Besler C, Lüscher TF and Landmesser U: Molecular mechanisms of vascular effects of high-density lipoprotein: Alternations in cardiovascular disease. EMBO Mol Med. 4:251–268. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Stary HC: The sequence of cell and matrix changes in athero-sclerotic lesions of coronary arteries in the first forty years of life. Eur Heart J. 11(Suppl E): S3–S19. 1990. View Article : Google Scholar | |
|
Sullivan MP, Cerda JJ, Robbins FL, Burgin CW and Beatty RJ: The gerbil, hamster, and guinea pig as rodent models for hyper-lipidemia. Lab Anim Sci. 43:575–578. 1993.PubMed/NCBI | |
|
Sima A, Stancu C, Constantinescu E, Ologeanu L and Simionescu M: The hyperlipemic hamster-a model for testing the anti-atherogenic effect of amlodipine. J Cell Mol Med. 5:153–162. 2001. View Article : Google Scholar | |
|
Ohmura H, Fukushima Y, Mizuno A, Niwa K, Kobayashi Y, Ebina T, Kimura K, Ishibashi S and Daida H: Research Committee on Primary Hyperlipidemia of the Ministry of Health and Welfare of Japan: Estimated prevalence of heterozygous familial hypercholesterolemia in patients with acute coronary syndrome. Int Heart J. 58:88–94. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Rosenson RS, Brewer HB Jr, Ansell BJ, Barter P, Chapman MJ, Heinecke JW, Kontush A, Tall AR and Webb NR: Dysfunctional HDL and atherosclerotic cardiovascular disease. Nat Rev Cardiol. 13:48–60. 2016. View Article : Google Scholar | |
|
Gistera A and Hansson GK: The immunology of atherosclerosis. Nat Rev Nephrol. 13:368–380. 2017. View Article : Google Scholar : PubMed/NCBI | |
|
Jonsson AL and Bäckhed F: Role of gut microbiota in atherosclerosis. Nat Rev Cardiol. 14:79–87. 2017. View Article : Google Scholar | |
|
Babicek K, Cehová I, Simon RR, Harwood M and Cox DJ: Toxicological assesment of a particulate yeast (1,3/1,6)-beta-D-glucan in rats. Food Chem Toxicol. 45:1719–1730. 2007. View Article : Google Scholar | |
|
Brown L, Rosner B, Willett WW and Sacks FM: Cholesterol-lowering effects of dietary fiber: A meta-analysis. Am J Clin Nutr. 69:30–42. 1999.PubMed/NCBI | |
|
Phillips GO and Cui SW: An introduction: Evolution and finalisation of the regulatory definition of dietary fibre. Food Hydrocolloids. 25:139–143. 2011. View Article : Google Scholar | |
|
Slavin JL: Dietary fiber and body weight. Nutrition. 21:4114182005. View Article : Google Scholar : PubMed/NCBI | |
|
Cheung PCK: Mini-review on edible mushrooms as source of dietary fiber: Preparation and health benefits. Food Sci Human Wellness. 2:162–166. 2013. View Article : Google Scholar | |
|
Jenkins DJ, Kendall CW, Axelsen M, Augustin LS and Vuksan V: Viscous and nonviscous fibres, nonabsorbable and low glycaemic index carbohydrates, blood lipids and coronary heart disease. Curr Opin Lipidol. 11:49–56. 2000. View Article : Google Scholar : PubMed/NCBI | |
|
Gee JM, Blackburn NA and Johnson IT: The influence of guar gum on intestinal cholesterol transport in the rat. Br J Nutr. 50:215–224. 1983. View Article : Google Scholar : PubMed/NCBI | |
|
Chau CF and Huang YL: Effects of the insoluble fiber derived from Passiflora edulis seed on plasma and hepatic lipids and fecal output. Mol Nutr Food Res. 49:786–790. 2005. View Article : Google Scholar : PubMed/NCBI | |
|
Cho IJ, Lee C and Ha TY: Hypolipidemic effect of soluble fiber isolated from seeds of Cassia tora Linn. In rats fed a high-cholesterol diet. J Agric Food Chem. 55:1592–1596. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Zacherl C, Eisner P and Engel KH: In vitro model to correlate viscosity and bile acid-binding capacity of digested water-soluble and insoluble dietary fibres. Food Chem. 126:423–428. 2011. View Article : Google Scholar | |
|
Aoki S, Iwai A, Kawata K, Muramatsu D, Uchiyama H, Okabe M, Ikesue M, Maeda N and Uede T: Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice. Sci Rep. 5:104572015. View Article : Google Scholar | |
|
Steinberg GR and Kemp BE: AMPK in health and disease. Physiol Rev. 89:1025–1078. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Kaczmarczyk MM, Miller MJ and Freund GG: The health benefits of dietary fiber: Beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer. Metabolism. 61:1058–1066. 2012. View Article : Google Scholar : PubMed/NCBI | |
|
Drew BG, Fidge NH, Gallon-Beaumier G, Kemp BE and Kingwell BA: High-density lipoprotein and apolipoprotein AI increase endothelial NO synthase activity by protein association and multisite phosphorylation. Proc Natl Acad Sci USA. 101:6999–7004. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Roy CC, Kien CL, Bouthillier L and Levy E: Short-chain fatty acids: Ready for prime time. Nutr Clin Pract. 21:351–366. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
den Besten G, van Eunen K, Groen AK, Venema K, Reijngoud DJ and Bakker BM: The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. 54:2325–2340. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Chan GC, Chan WK and Sze DM: The effects of beta-glucan on human immune and cancer cells. J Hematol Oncol. 2:252009. View Article : Google Scholar : PubMed/NCBI | |
|
Al-Lahham SH, Peppelenbosch MP, Roelofsen H, Vonk RJ and Venema K: Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms. Biochim Biophys Acta. 1801:1175–1183. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Wismar R, Brix S, Frøkiaer H and Laerke HN: Dietary fibers as immunoregulatory compounds in health and disease. Ann NY Acad Sci. 1190:70–85. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Vangaveti V, Shashidhar V, Jarrod G, Baune BT and Kennedy RL: Free fatty acid receptors: Emerging targets for treatment of diabetes and its complications. Ther Adv Endocrinol Metab. 1:165–175. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Warnberg J, Gomez-Martinez S, Romeo J, Diaz LE and Marcos A: Nutrition, inflammation, and cognitive function. Ann N Y Acad Sci. 1153:164–175. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Cosola C, De Angelis M, Rocchetti MT, Montemurno E, Maranzano V, Dalfino G, Manno C, Zito A, Gesualdo M, Ciccone MM, et al: Beta-glucans supplementation associates with reduction in P-Cresyl sulfate levels and improved endo-thelial vascular reactivity in healthy individuals. PLoS One. 12:e01696352017. View Article : Google Scholar | |
|
Mansbach CM II and Gorelick F: Development and physiological regulation of intestinal lipid absorption. II. Dietary lipid absorption, complex lipid synthesis, and the intracellular packaging and secretion of chylomicrons. Am J Physiol Gastrointest Liver Physiol. 293:G645–G650. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Black DD: Development and physiological regulation of intestinal lipid absorption. I. Development of intestinal lipid absorption: Cellular events in chylomicron assembly and secretion. Am J Physiol Gastrointest Liver Physiol. 293:G519–G524. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Brown MS and Goldstein JL: The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor. Cell. 89:331–340. 1997. View Article : Google Scholar : PubMed/NCBI | |
|
Sato R: Sterol metabolism and SREBP activation. Arch Biochem Biophys. 501:177–181. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Drozdowski LA, Reimer RA, Temelli F, Bell RC, Vasanthan T and Thomson AB: Beta-glucan extracts inhibit the in vitro intestinal uptake of long-chain fatty acids and cholesterol and down-regulate genes involved in lipogenesis and lipid transport in rats. J Nutr Biochem. 21:695–701. 2010. View Article : Google Scholar | |
|
Chen J and Huang XF: The effects of diets enriched in beta-glucans on blood lipoprotein concentrations. J Clin Lipidol. 3:154–158. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
Rondanelli M, Opizzi A, Monteferrario F, Klersy C, Cazzola R and Cestaro B: Beta-glucan- or rice bran-enriched foods: A comparative crossover clinical trial on lipidic pattern in mildly hypercholesterolemic men. Eur J Clin Nutr. 65:864–871. 2011. View Article : Google Scholar : PubMed/NCBI | |
|
Wolever TM, Tosh SM, Gibbs AL, Brand-Miller J, Duncan AM, Hart V, Lamarche B, Thomson BA, Duss R and Wood PJ: Physicochemical properties of oat β-glucan influence its ability to reduce serum LDL cholesterol in humans: A randomized clinical trial. Am J Clin Nutr. 92:723–732. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Johnson IT and Gee JM: Effect of gel-forming gums on the intestinal unstirred layer and sugar transport in vitro. Gut. 22:398–403. 1981. View Article : Google Scholar : PubMed/NCBI | |
|
Kirby RW, Anderson JW, Sieling B, Rees ED, Chen WJ, Miller RE and Kay RM: Oat-bran intake selectively lowers serum low-density lipoprotein cholesterol concentrations of hypercholesterolemic men. Am J Clin Nutr. 34:824–829. 1981.PubMed/NCBI | |
|
Fadel JG, Newman RK, Newman CW and Barnes AE: Hypocholesterolemic effects of beta-glucans in different barley diets fed to broiler chicks. Nutr Rep Int. 35:1049–1058. 1987. | |
|
Li J, Kaneko T, Qin LQ, Wang J, Wang Y and Sato A: Long-term effects of high dietary fiber intake on glucose tolerance and lipid metabolism in GK rats: Comparison among barley, rice, and cornstarch. Metabolism. 52:1206–1210. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Sima A, Bulla A and Simionescu N: Experimental obstructive coronary atherosclerosis in the hyperlipidemic hamster. J Submicrosc Cytol Pathol. 22:1–16. 1990.PubMed/NCBI | |
|
Lim MK, Ku SK, Choi JS and Kim JW: Effect of polycan, a β-glucan originating from Aureobasidium, on a high-fat diet-induced hyperlipemic hamster model. Exp Ther Med. 9:1369–1378. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Delaney B, Nicolosi RJ, Wilson TA, Carlson T, Frazer S, Zheng GH, Hess R, Ostergren K, Haworth J and Knutson N: Beta-glucan fractions from barley and oats are similarly anti-atherogenic in hypercholesterolemic Syrian golden hamsters. J Nutr. 133:468–475. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Wilson TA, Nicolosi RJ, Delaney B, Chadwell K, Moolchandani V, Kotyla T, Ponduru S, Zheng GH, Hess R, Knutson N, et al: Reduced and high molecular weight barley beta-glucans decrease plasma total and non-HDL-cholesterol in hypercholesterolemic Syrian golden hamsters. J Nutr. 134:2617–2622. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Wu YS, Ho SY, Nan FH and Chen SN: Ganoderma lucidum beta 1,3/1,6 glucan as an immunomodulator in inflammation induced by a high-cholesterol diet. BMC Complement Altern Med. 16:5002016. View Article : Google Scholar : PubMed/NCBI | |
|
Kusmiati and Dhewantara FX: Cholesterol-lowering effect of beta glucan extracted from Saccharomyces cerevisiae in rats. Sci Pharm. 84:153–165. 2016. View Article : Google Scholar : PubMed/NCBI | |
|
Tong LT, Zhong K, Liu L, Zhou X, Qiu J and Zhou S: Effects of dietary hull-less barley β-glucan on the cholesterol metabolism of hypercholesterolemic hamsters. Food Chem. 169:344–349. 2015. View Article : Google Scholar | |
|
Vetvicka V and Vetvickova J: Physiological effects of different types of beta-glucan. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 151:225–231. 2007. View Article : Google Scholar | |
|
Malkki Y: Oat fiber. Food Science and Technology: Handbook of Dietary Fiber. Cho S and Dreher ML: M. Dekker; New York: pp. 497–512. 2001 | |
|
Veniant MM, Withycombe S and Young SG: Lipoprotein size and atherosclerosis susceptibility in Apoe−/− and Ldlr−/− mice. Arterioscler Thromb Vasc Biol. 21:1567–1570. 2001. View Article : Google Scholar | |
|
Pendse AA, Arbones-Mainar JM, Johnson LA, Altenburg MK and Maeda N: Apolipoprotein E knock-out and knock-in mice: Atherosclerosis, metabolic syndrome, and beyond. J Lipid Res. 50(Suppl): S178–S182. 2009. View Article : Google Scholar : | |
|
Anderson JW, Story L, Sieling B, Chen WJ, Petro MS and Story J: Hypocholesterolemic effects of oat-bran or bean intake for hypercholesterolemic men. Am J Clin Nutr. 40:1146–1155. 1984. View Article : Google Scholar : PubMed/NCBI | |
|
Anderson JW and Gustafson NJ: Hypocholesterolemic effects of oat and bean products. Am J Clin Nutr. 48(Suppl 3): S749–S753. 1988. View Article : Google Scholar | |
|
Braaten JT, Wood PJ, Scott FW, Wolynetz MS, Lowe MK, Bradley-White P and Collins MW: Oat beta-glucan reduces blood cholesterol concentration in hypercholesterolemic subjects. Eur J Clin Nutr. 48:465–474. 1994.PubMed/NCBI | |
|
Newman RK, Lewis SE, Newman CW, Boik RJ and Ramage RT: Hypocholesterolemic effect of barley foods on healthy men. Nutr Rep Int. 39:749–760. 1989. | |
|
McIntosh GH, Whyte J, McArthur R and Nestel PJ: Barley and wheat foods: Influence on plasma cholesterol concentrations in hypercholesterolemic men. Am J Clin Nutr. 53:1205–1209. 1991. View Article : Google Scholar : PubMed/NCBI | |
|
Lupton JR, Robinson MC and Morin JL: Cholesterol-lowering effect of barley bran flour and oil. J Am Diet Assoc. 94:65–70. 1994. View Article : Google Scholar : PubMed/NCBI | |
|
Lia A, Hallmans G, Sandberg AS, Sundberg B, Aman P and Anderson H: Oat beta-glucan increases bile excretion and a fiber rich barley fracton increases cholesterol excretion in ileostomy subjects. Am J Clin Nutr. 62:1245–1251. 1995. View Article : Google Scholar : PubMed/NCBI | |
|
Bell S, Goldman VM, Bistrian BR, Arnold AH, Ostroff G and Forse RA: Effect of beta-glucan from oats and yeast on serum lipids. Crit Rev Food Sci Nutr. 39:189–202. 1999. View Article : Google Scholar : PubMed/NCBI | |
|
Li J, Kaneko T, Qin LQ, Wang J and Wang Y: Effects of barley intake on glucose tolerance, lipid metabolism, and bowel function in women. Nutrition. 19:926–929. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Behall KM, Scholfield DJ and Hallfrisch J: Diets containing barley significantly reduce lipids in mildly hypercholesterolemic men and women. Am J Clin Nutr. 80:1185–1193. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Behall KM, Scholfield DJ and Hallfrisch J: Lipids significantly reduced by diets containing barley in moderately hypercholes-terolemic men. J Am Coll Nutr. 23:55–62. 2004. View Article : Google Scholar : PubMed/NCBI | |
|
Keenan JM, Goulson M, Shamliyan T, Knutson N, Kolberg L and Curry L: The effects of concentrated barley beta-glucan on blood lipids in a population of hypercholesterolaemic men and women. Br J Nutr. 97:1162–1168. 2007. View Article : Google Scholar : PubMed/NCBI | |
|
Shimizu C, Kihara M, Aoe S, Araki S, Ito K, Hayashi K, Watari J, Sakata Y and Ikegami S: Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men-a randomized, double-blinded, placebo-controlled trial. Plant Foods Hum Nutr. 63:21–25. 2008. View Article : Google Scholar | |
|
Sundberg B: Cholesterol lowering effects of a barley fibre flake product. Agro Food Industry Hi-Tech. 19:14–17. 2008. | |
|
Zhu X, Sun X, Wang M, Zhang C, Cao Y, Mo G, Liang J and Zhu S: Quantitative assessment of the effects of beta-glucan consumption on serum lipid profile and glucose level in hypercholesterolemic subjects. Nutr Metab Cardiovasc Dis. 25:714–723. 2015. View Article : Google Scholar : PubMed/NCBI | |
|
Keogh GF, Cooper GJ, Mulvey TB, McArdle BH, Coles GD, Monro JA and Poppitt SD: Randomized controlled crossover study of the effect of a highly beta-glucan-enriched barley on cardiovascular disease risk factors in mildly hypercholesterol-emic men. Am J Clin Nutr. 78:711–718. 2003. View Article : Google Scholar : PubMed/NCBI | |
|
Biörklund M, van Rees A, Mensink RP and Onning G: Changes in serum lipids and postprandial glucose and insulin concentrations after consumption of beverages with beta-glucans from oats or barley: A randomised dose-controlled trial. Eur J Clin Nutr 5. 9:1272–1281. 2005. View Article : Google Scholar | |
|
Ibrügger S, Kristensen M, Poulsen MW, Mikkelsen MS, Ejsing J, Jespersen BM, Dragsted LO, Engelsen SB and Bügel S: Extracted oat and barley β-glucans do not affect cholesterol metabolism in young healthy adults. J Nutr. 143:1579–1585. 2013. View Article : Google Scholar | |
|
Talati R, Baker WL, Pabilonia MS, White CM and Coleman CI: The effects of barley-derived soluble fiber on serum lipids. Ann Fam Med. 7:157–163. 2009. View Article : Google Scholar : PubMed/NCBI | |
|
AbuMweis SS, Jew S and Ames NP: β-glucan from barley and its lipid-lowering capacity: A meta-analysis of randomized, controlled trials. Eur J Clin Nutr. 64:1472–1480. 2010. View Article : Google Scholar : PubMed/NCBI | |
|
Anderson TJ, Grégoire J, Hegele RA, Couture P, Mancini GB, McPherson R, Francis GA, Poirier P, Lau DC, Grover S, et al: 2012 update of the Canadian Cardiovascular Society guidelines for the diagnosis and treatment of dyslipidemia for the prevention of cardiovascular disease in the adult. Can J Cardiol. 29:151–167. 2013. View Article : Google Scholar : PubMed/NCBI | |
|
Newman RK and Newman CW: Barley for food and health: Science, technology, and products. Genetics and Nutrient Composition. John Wiley & Sons; Hoboken, NJ: pp. 56–94. 2008 | |
|
Ho HV, Sievenpiper JL, Zurbau A, Blanco Mejia S, Jovanovski E, Au-Yeung F, Jenkins AL and Vuksan V: A systematic review and meta-analysis of randomized controlled trials of the effect of barley β-glucan on LDL-C, non-HDL-C and apoB for cardiovascular disease risk reductioni-iv. Eur J Clin Nutr. 70:13402016. View Article : Google Scholar | |
|
Mori K, Kobayashi C, Tomita T, Inatomi S and Ikeda M: Antiatherosclerotic effect of the edible mushrooms Pleurotus eryngii (Eringi), Grifola frondosa (Maitake), and Hypsizygus marmoreus (Bunashimeji) in apolipoprotein E-deficient mice. Nutr Res. 28:335–342. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Sun JE, Ao ZH, Lu ZM, Xu HY, Zhang XM, Dou WF and Xu ZH: Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol. 118:7–13. 2008. View Article : Google Scholar : PubMed/NCBI | |
|
Bays HE, Evans JL, Maki KC, Evans M, Maquet V, Cooper R and Anderson JW: Chitin-glucan fiber effects on oxidized low-density lipoprotein: A randomized controlled trial. Eur J Clin Nutr. 67:2–7. 2013. View Article : Google Scholar : | |
|
Serra-Majem L, Roman B and Estruch R: Scientific evidence of interventions using the Mediterranean diet: A systematic review. Nutr Rev. 64(Suppl): S27–S47. 2006. View Article : Google Scholar : PubMed/NCBI | |
|
Wang Y, Harding SV, Eck P, Thandapilly SJ, Gamel TH, Abdel-Aal el-SM, Crow GH, Tosh SM, Jones PJ and Ames NP: High-molecular-weight β-glucan decreases serum cholesterol differentially based on the CYP7A1 rs3808607 polymorphism in mildly hypercholesterolemic adults. J Nutr. 146:720–727. 2016. View Article : Google Scholar : PubMed/NCBI |
