Journal Articles
Review
β-glucans and cholesterol (Review)
Petr Sima, Luca Vannucci, Vaclav Vetvicka
Pages: 1799-1808 Published online on: 22 January 2018
Review
Role of exosomes and exosomal microRNAs in hepatocellular carcinoma: Potential in diagnosis and antitumour treatments (Review)
Jing‑Hua Pan, Hong Zhou, Xiao‑Xu Zhao, Hui Ding, Wei Li, Li Qin, Yun‑Long Pan
Pages: 1809-1816 Published online on: 11 January 2018
Review
Damage to dopaminergic neurons by oxidative stress in Parkinson's disease (Review)
Ji‑Dong Guo, Xin Zhao, Yang Li, Guang‑Ren Li, Xiao‑Liang Liu
Pages: 1817-1825 Published online on: 19 January 2018
Article
D‑Pinitol alleviates cyclosporine A‑induced renal tubulointerstitial fibrosis via activating Sirt1 and Nrf2 antioxidant pathways
Eun Sil Koh, Soojeong Kim, Minyoung Kim, Yu Ah Hong, Seok Joon Shin, Cheol Whee Park, Yoon Sik Chang, Sungjin Chung, Ho‑Shik Kim
Pages: 1826-1834 Published online on: 19 January 2018
Article
Preliminary study of microRNA-126 as a novel therapeutic target for primary hypertension
Jia Liu, Jiamei Liu, Linying Shi, Fan Zhang, Liping Yu, Xinchun Yang, Jun Cai
Pages: 1835-1844 Published online on: 23 January 2018
Article
Honokiol suppresses proliferation and induces apoptosis via regulation of the miR‑21/PTEN/PI3K/AKT signaling pathway in human osteosarcoma cells
Jiexiang Yang, Yonggen Zou, Dianmin Jiang
Pages: 1845-1854 Published online on: 29 January 2018
Article
miR‑21‑5p confers doxorubicin resistance in gastric cancer cells by targeting PTEN and TIMP3
Jun Chen, Chao Zhou, Junhe Li, Xiaojun Xiang, Ling Zhang, Jun Deng, Jianping Xiong
Pages: 1855-1866 Published online on: 18 January 2018
Article
Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway
Maojun Liu, Yan Li, Biao Liang, Zining Li, Zhengtao Jiang, Chun Chu, Jun Yang
Pages: 1867-1876 Published online on: 23 January 2018
Article
Increased expression of sterol regulatory element binding protein‑2 alleviates autophagic dysfunction in NAFLD
Chunwei Cheng, Xiaoling Deng, Keshu Xu
Pages: 1877-1886 Published online on: 16 January 2018
Article
Resistant starch prevents tumorigenesis of dimethylhydrazine-induced colon tumors via regulation of an ER stress-mediated mitochondrial apoptosis pathway
Qiuyu Wang, Peng Wang, Zhigang Xiao
Pages: 1887-1898 Published online on: 25 January 2018
Article
miR‑186, a serum microRNA, induces endothelial cell apoptosis by targeting SMAD6 in Kawasaki disease
Rongzhou Wu, Danping Shen, Hareshwaree Sohun, Donghui Ge, Xianda Chen, Xuliang Wang, Ruiyao Chen, Yuqing Wu, Jingjing Zeng, Xing Rong, Xiaoping Su, Maoping Chu
Pages: 1899-1908 Published online on: 18 January 2018
Article
MicroRNA-327 regulates cardiac hypertrophy and fibrosis induced by pressure overload
Yue Ji, Ming Qiu, Yejiao Shen, Li Gao, Yaqing Wang, Wei Sun, Xinli Li, Yan Lu, Xiangqing Kong
Pages: 1909-1916 Published online on: 25 January 2018
Article
Aberrantly expressed long noncoding RNAs in hypertrophic scar fibroblasts in vitro: A microarray study
Longxiang Tu, Qi Huang, Shangfeng Fu, Dewu Liu
Pages: 1917-1930 Published online on: 26 January 2018
Article
Extracorporeal shock wave therapy with low-energy flux density inhibits hypertrophic scar formation in an animal model
Jing-Chun Zhao, Bo-Ru Zhang, Lei Hong, Kai Shi, Wei-Wei Wu, Jia-Ao Yu
Pages: 1931-1938 Published online on: 29 January 2018
Article
Suppressive effects of berberine on atherosclerosis via downregulating visfatin expression and attenuating visfatin-induced endothelial dysfunction
Qiang Wan, Zhongyong Liu, Yuping Yang, Xiaobing Cui
Pages: 1939-1948 Published online on: 30 January 2018
Article
EZH2-mediated suppression of lncRNA-LET promotes cell apoptosis and inhibits the proliferation of post-burn skin fibroblasts
Weicai Zheng, Aixiang Yu
Pages: 1949-1957 Published online on: 25 January 2018
Article
Regulation of drug resistance and metastasis of gastric cancer cells via the microRNA647-ANK2 axis
Wenlong Cao, Weiyuan Wei, Zexu Zhan, Dongyi Xie, Yubo Xie, Qiang Xiao
Pages: 1958-1966 Published online on: 11 January 2018
Article
Breast cancer stem-like cells are sensitized to tamoxifen induction of self-renewal inhibition with enforced Let-7c dependent on Wnt blocking
Xin Sun, Chongwen Xu, Guodong Xiao, Jinying Meng, Jichang Wang, Shou‑Ching Tang, Sida Qin, Ning Du, Gang Li, Hong Ren, Dapeng Liu
Pages: 1967-1975 Published online on: 15 January 2018
Article
Interleukin-1β induces intercellular adhesion molecule-1 expression, thus enhancing the adhesion between mesenchymal stem cells and endothelial progenitor cells via the p38 MAPK signaling pathway
Jun Guo, Hongwei Zhang, Jie Xia, Jixue Hou, Yixiao Wang, Tao Yang, Sibo Wang, Xuyong Zhang, Xuelin Chen, Xiangwei Wu
Pages: 1976-1982 Published online on: 25 January 2018
Article
MicroRNA‑32 silences WWP2 expression to maintain the pluripotency of human amniotic epithelial stem cells and β islet‑like cell differentiation
Gang Zou, Te Liu, Lihe Guo, Yongyi Huang, Ya Feng, Tao Duan
Pages: 1983-1991 Published online on: 29 January 2018
Article
Baicalin inhibits PDGF-BB-induced hepatic stellate cell proliferation, apoptosis, invasion, migration and activation via the miR-3595/ACSL4 axis
Xiongjian Wu, Fachao Zhi, Weijian Lun, Qiliang Deng, Wendi Zhang
Pages: 1992-2002 Published online on: 25 January 2018
Article
Effect of midkine on gemcitabine resistance in biliary tract cancer
Yongliang Lu, Bing Yan, Huihui Guo, Li Qiu, Xinrong Sun, Xiang Wang, Qian Shi, Ying Bao
Pages: 2003-2011 Published online on: 18 January 2018
Article
Two novel variants of the PHEX gene in patients with X‑linked dominant hypophosphatemic rickets and prenatal diagnosis for fetuses in these families
Hong Liao, Hong‑Mei Zhu, Hong‑Qian Liu, Ling‑Ping Li, Shan‑Ling Liu, He Wang
Pages: 2012-2020 Published online on: 18 January 2018
Article
A 65‑gene signature for prognostic prediction in colon adenocarcinoma
Hui Jiang, Jun Du, Jiming Gu, Liugen Jin, Yong Pu, Bojian Fei
Pages: 2021-2027 Published online on: 18 January 2018
Article
Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells
Wanlin Liu, Zhenqun Zhao, Yuyan Na, Chenyang Meng, Jianzhong Wang, Rui Bai
Pages: 2028-2036 Published online on: 23 January 2018
Article
Effect of leukocyte inhibitory factor on neuron differentiation from human induced pluripotent stem cell-derived neural precursor cells
Liping Xu, Jingyi Long, Chun Shi, Nianping Zhang, Ying Lv, Junda Feng, Aiguo Xuan, Xiaosong He, Qingqing Li, Yinshan Bai, Shanshan Liu, Dahong Long
Pages: 2037-2049 Published online on: 23 January 2018
Article
miR-133b reverses cisplatin resistance by targeting GSTP1 in cisplatin-resistant lung cancer cells
Chen Lin, Liyi Xie, Yan Lu, Zhihuang Hu, Jianhua Chang
Pages: 2050-2058 Published online on: 11 January 2018
Article
Gastrodin protects MC3T3-E1 osteoblasts from dexamethasone-induced cellular dysfunction and promotes bone formation via induction of the NRF2 signaling pathway
Shengye Liu, Tao Fang, Liyu Yang, Zhiguang Chen, Shuai Mu, Qin Fu
Pages: 2059-2069 Published online on: 23 January 2018
Article
A 63 signature genes prediction system is effective for glioblastoma prognosis
Yang Zhang, Jiaming Xu, Xiangdong Zhu
Pages: 2070-2078 Published online on: 25 January 2018
Article
Baicalin increases hair follicle development by increasing canonical Wnt/β‑catenin signaling and activating dermal papillar cells in mice
Fei Xing, Wen‑Juan Yi, Fang Miao, Meng‑Yun Su, Tie‑Chi Lei
Pages: 2079-2085 Published online on: 16 January 2018
Article
Autophagy regulates the degeneration of the auditory cortex through the AMPK-mTOR-ULK1 signaling pathway
Jie Yuan, Xueyan Zhao, Yujuan Hu, Haiying Sun, Guoqing Gong, Xiang Huang, Xubo Chen, Mingyu Xia, Chen Sun, Qilin Huang, Yu Sun, Wen Kong, Weijia Kong
Pages: 2086-2098 Published online on: 17 January 2018
Article
Therapeutic potential of a dual mTORC1/2 inhibitor for the prevention of posterior capsule opacification: An in vitro study
Hao Feng, Zhibo Yang, Xue Bai, Meirong Yang, Yuan Fang, Xiaonan Zhang, Qiqiang Guo, Hong Ning
Pages: 2099-2107 Published online on: 18 January 2018
Article
Schizandrin B inhibits the cis‑DDP‑induced apoptosis of HK‑2 cells by activating ERK/NF‑κB signaling to regulate the expression of survivin
Qiang Liu, Jinxin Song, Hong Li, Lei Dong, Shejiao Dai
Pages: 2108-2116 Published online on: 19 January 2018
Article
Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways
Pengcheng Wang, Zekai Mao, Qiyong Pan, Rui Lu, Xiaojian Huang, Xiaobin Shang, Rui Zhang, Hongbo You
Pages: 2117-2127 Published online on: 22 January 2018
Article
Bu-Fei decoction and modified Bu-Fei decoction inhibit the growth of non-small cell lung cancer, possibly via inhibition of apurinic/apyrimidinic endonuclease 1
Shan‑Tong Jiang, Shu‑Yan Han, Li‑Na Pang, Yan‑Na Jiao, Xi‑Ran He, Ping‑Ping Li
Pages: 2128-2138 Published online on: 30 January 2018
Article
MicroRNA-139-5p/Flt1/Wnt/β-catenin regulatory crosstalk modulates the progression of glioma
Qiong Wang, Bin Xu, Jixiang Du, Xinnv Xu, Chao Shang, Xiuyu Wang, Jinhuan Wang
Pages: 2139-2149 Published online on: 30 January 2018
Article
Nano-hydroxyapatite/collagen film as a favorable substrate to maintain the phenotype and promote the growth of chondrocytes cultured in vitro Corrigendum in /10.3892/ijmm.2020.4743 Corrigendum in /10.3892/ijmm.2022.5146
Xianfang Jiang, Yanping Zhong, Li Zheng, Jinmin Zhao
Pages: 2150-2158 Published online on: 26 January 2018
Article
Expression level of 12-amino acid triggering receptor on myeloid cells-like transcript 1 derived peptide alleviates lipopolysaccharide-induced acute lung injury in mice
Ruili Shi, Jiancheng Zhang, Zhang Peng, Shiying Yuan, Sumin Gao, Lin Chen, Yin Yuan
Pages: 2159-2168 Published online on: 30 January 2018
Article
Engineered zinc-finger transcription factors inhibit the replication and transcription of HBV in vitro and in vivo
Wei Luo, Junxia Wang, Dengfeng Xu, Huili Bai, Yangli Zhang, Yuhong Zhang, Xiaosong Li
Pages: 2169-2176 Published online on: 17 January 2018
Article
Targeted disruption of adenosine kinase in myeloid monocyte cells increases osteoclastogenesis and bone resorption in mice
Qiuying Ye, Ge Li, Shuhua Liu, Yalun Guan, Yunfeng Li, Jinling Li, Huanhuan Jia, Xuejiao Li, Qingnan Li, Ren Huang, Hui Wang, Yu Zhang
Pages: 2177-2184 Published online on: 17 January 2018
Article
Annexin A9 promotes invasion and metastasis of colorectal cancer and predicts poor prognosis
Suyang Yu, Honglei Bian, Xin Gao, Lin Gui
Pages: 2185-2192 Published online on: 29 January 2018
Article
Lentivirus-mediated overexpression of suppressor of cytokine signaling-3 reduces neutrophilic airway inflammation by suppressing T-helper 17 responses in mice with chronic Pseudomonas aeruginosa lung infections
Feng‑Ming Ding, Xing‑Yi Zhang, Yu‑Qing Chen, Ruo‑Min Liao, Guo‑Gang Xie, Peng‑Yu Zhang, Ping Shao, Min Zhang
Pages: 2193-2200 Published online on: 23 January 2018
Article
Feasibility analysis of treating severe intrauterine adhesions by transplanting menstrual blood-derived stem cells
Sheng‑Xia Zheng, Jian Wang, Xue‑Li Wang, Asim Ali, Li‑Min Wu, Yu‑Sheng Liu
Pages: 2201-2212 Published online on: 23 January 2018
Article
Effects of silencing the DUSP1 gene using lentiviral vector-mediated siRNA on the release of proinflammatory cytokines through regulation of the MAPK signaling pathway in mice with acute pancreatitis
Bo Zhang, Shu‑Liang Li, Hua‑Lei Xie, Jia‑Wei Fan, Chuan‑Wei Gu, Chao Kang, Mu‑Jian Teng
Pages: 2213-2224 Published online on: 25 January 2018
Article
Downregulation of adult and neonatal Nav1.5 in the dorsal root ganglia and axon of peripheral sensory neurons of rats with spared nerve injury
Jun Wang, Shao-Wu Ou, Yun-Fei Bai, Yun-Jie Wang, Zhi-Qing David Xu, Guo-Ming Luan
Pages: 2225-2232 Published online on: 30 January 2018
Article
Adaptive unfolded protein response promotes cell survival in rifampicin-treated L02 cells
Weiping Zhang, Jianming Xu
Pages: 2233-2242 Published online on: 29 January 2018
Article
MicroRNA let-7g inhibits angiotensin II-induced endothelial senescence via the LOX-1-independent mechanism
Po‑Yuan Hsu, Wen‑Yi Lin, Ruey‑Tay Lin, Suh‑Hang H. Juo
Pages: 2243-2251 Published online on: 23 January 2018
Article
Magnolol protects against ischemic-reperfusion brain damage following oxygen-glucose deprivation and transient focal cerebral ischemia
Sheng‑Yang Huang, Shih‑Huang Tai, Che‑Chao Chang, Yi‑Fang Tu, Chih‑Han Chang, E‑Jian Lee
Pages: 2252-2262 Published online on: 15 January 2018
Article
Dengue virus-1 NS5 genetic variant associated with a severe clinical infection: Possible reduction of the innate immune response by inhibition of interferon type 1 and the Janus kinase-signal transducer and activator of transcription signaling pathway
Iván Delgado‑Enciso, Uriel A. López‑Lemus, Jose A. Valcarcel‑Gamiño, Iram P. Rodriguez‑Sanchez, Salvador Valle‑Reyes, Margarita L. Martinez‑Fierro, Valery Melnikov, José Guzmán‑Esquivel, Felipe Vaca‑Paniagua, Laura L. Valdez‑Velazquez, Luz M. Baltazar‑Rodriguez, Alejandro D. Soriano‑Hernandez, Brenda Paz‑Michel, Francisco Espinoza‑Gómez
Pages: 2263-2269 Published online on: 17 January 2018
Article
CTHRC1 mediates IL‑1β‑induced apoptosis in chondrocytes via JNK1/2 signaling
Qi Zhang, Zong‑Sheng Yin, Fu‑Wen Zhang, Kun Cao, He‑Yan Sun
Pages: 2270-2278 Published online on: 18 January 2018
Article
The NALP3 inflammasome is required for collagen synthesis via the NF‑κB pathway
Ju Kuang, Min Xie, Xiaolin Wei
Pages: 2279-2287 Published online on: 18 January 2018
Article
Underlying mechanism of the photodynamic activity of hematoporphyrin‑induced apoptosis in U87 glioma cells
Shi‑Xiang Yuan, Jun‑Liang Li, Xin‑Ke Xu, Wei Chen, Cheng Chen, Kun‑Qi Kuang, Fang‑Yu Wang, Kai Wang, Fang‑Cheng Li
Pages: 2288-2296 Published online on: 18 January 2018
Article
Carbon monoxide releasing molecule‑3 promotes the osteogenic differentiation of rat bone marrow mesenchymal stem cells by releasing carbon monoxide
Jingyuan Li, Ling Song, Meng Hou, Ping Wang, Lingling Wei, Hui Song
Pages: 2297-2305 Published online on: 29 January 2018
Article
NOX4/ROS mediate ethanol‑induced apoptosis via MAPK signal pathway in L‑02 cells
Cheng‑Fang Yang, Yu‑Juan Zhong, Zuheng Ma, Li Li, Lin Shi, Li Chen, Chen Li, Dan Wu, Qi Chen, Yong‑Wen Li
Pages: 2306-2316 Published online on: 16 January 2018
Article
TNF-α induces Drp1-mediated mitochondrial fragmentation during inflammatory cardiomyocyte injury
Yue‑Liang Shen, Ying‑Zhou Shi, Gai‑Ge Chen, Lin‑Lin Wang, Ming‑Zhi Zheng, Hong‑Feng Jin, Ying‑Ying Chen
Pages: 2317-2327 Published online on: 15 January 2018
Article
Reduced mitochondrial response sensitivity is involved in the anti‑apoptotic effect of dexmedetomidine pretreatment in cardiomyocytes
Xiaojian Weng, Xiaodan Zhang, Xiaofei Lu, Jin Wu, Shitong Li
Pages: 2328-2338 Published online on: 12 January 2018
Article
Decreased ZONAB expression promotes excessive transdifferentiation of alveolar epithelial cells in hyperoxia-induced bronchopulmonary dysplasia
Ana Hou, Jianhua Fu, Yongyan Shi, Lin Qiao, Jun Li, Yujiao Xing, Xindong Xue
Pages: 2339-2349 Published online on: 23 January 2018
Article
miR-195 suppresses abdominal aortic aneurysm through the TNF-α/NF-κB and VEGF/PI3K/Akt pathway
Xiaohui Ma, Hairong Yao, Yuhong Yang, Long Jin, Yu Wang, Lina Wu, Shengli Yang, Kang Cheng
Pages: 2350-2358 Published online on: 25 January 2018
Article
Low-dose cadmium activates the JNK signaling pathway in human renal podocytes
Xiaocui Chen, Yinghua Xu, Zuowang Cheng, Hong Su, Xiu Liu, Dongmei Xu, Carolyn Kapron, Ju Liu
Pages: 2359-2365 Published online on: 30 January 2018
Article
Transcriptional regulation of HIV-1 host factor COMMD1 by the Sp family
Eriko Kudo, Manabu Taura, Mary Ann Suico, Hiroki Goto, Hirofumi Kai, Seiji Okada
Pages: 2366-2374 Published online on: 15 January 2018
Article
Renal transplantation increases angiotensin II receptor-mediated vascular contractility associated with changes of epigenetic mechanisms
Yakun Zhao, Qingguo Zhu, Shiping Sun, Yu Qiu, Jingquan Li, Wei Liu, Gangjun Yuan, Hua Ma
Pages: 2375-2388 Published online on: 29 January 2018
Article
Tanshinone IIA inhibits gastric carcinoma AGS cells by decreasing the protein expression of VEGFR and blocking Ras/Raf/MEK/ERK pathway
Chin-Cheng Su
Pages: 2389-2396 Published online on: 19 January 2018
Article
Genetic correction of adipose tissue-derived mesenchymal stem cells mediated by TALEN targeting the GDF5 gene
Baofeng Li, Ying Zhang, Mei Li, Xiaoliang Zhao, Huibin Xie, Xiaoze Guo, Fei Wang, Hong Xia, Bei Chen
Pages: 2397-2405 Published online on: 30 January 2018
Article
Neuroprotective effects of p53/microRNA‑22 regulate inflammation and apoptosis in subarachnoid hemorrhage
Shui Yu, Yi‑Jun Zeng, Xiao‑Chuan Sun
Pages: 2406-2412 Published online on: 16 January 2018
Article
Redox induces diverse effects on recombinant human wild-type PrP and mutated PrP with inserted or deleted octarepeats
Qi Shi, Cao Chen, Bao‑Yun Zhang, Wei Zhou, Kang Xiao, Xiao‑Ping Dong
Pages: 2413-2419 Published online on: 30 January 2018
Article
Relaxant and vasoprotective effects of ginger extracts on porcine coronary arteries
Hsing‑Chen Wu, Chi‑Ting Horng, Shih‑Chang Tsai, You‑Li Lee, Shou‑Cheng Hsu, Yi‑Jen Tsai, Fuu‑Jen Tsai, Jo‑Hua Chiang, Daih‑Huang Kuo, Jai‑Sing Yang
Pages: 2420-2428 Published online on: 11 January 2018
Article