|
1
|
Yu B, Kim HW, Gong M, Wang J, Millard RW,
Wang Y, Ashraf M and Xu M: Exosomes secreted from GATA-4
overexpressing mesenchymal stem cells serve as a reservoir of
anti-apoptotic microRNAs for cardioprotection. Int J Cardiol.
182:349–360. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Barile L, Lionetti V, Cervio E, Matteucci
M, Gherghiceanu M, Popescu LM, Torre T, Siclari F, Moccetti T and
Vassalli G: Extracellular vesicles from human cardiac progenitor
cells inhibit cardiomyocyte apoptosis and improve cardiac function
after myocardial infarction. Cardiovasc Res. 103:530–541. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Sluijter JP, Verhage V, Deddens JC, van
den Akker F and Doevendans PA: Microvesicles and exosomes for
intracardiac communication. Cardiovasc Res. 102:302–311. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Waqas MY, Zhang Q, Ahmed N, Yang P, Xing
G, Akhtar M, Basit A, Liu T, Hong C, Arshad M, et al: Cellular
evidence of exosomes in the reproductive tract of Chinese
soft-shelled turtle pelodiscus sinensis. J Exp Zool A Ecol Genet
Physiol. 327:18–27. 2017.
|
|
5
|
Ailawadi S, Wang X, Gu H and Fan GC:
Pathologic function and therapeutic potential of exosomes in
cardiovascular disease. Biochim Biophys Acta. 1852:1–11. 2015.
View Article : Google Scholar
|
|
6
|
Kharaziha P, Ceder S, Li Q and Panaretakis
T: Tumor cell-derived exosomes: A message in a bottle. Biochim
Biophys Acta. 1826:103–111. 2012.PubMed/NCBI
|
|
7
|
Kalani A, Tyagi A and Tyagi N: Exosomes:
Mediators of neurode-generation, neuroprotection and therapeutics.
Mol Neurobiol. 49:590–600. 2014. View Article : Google Scholar
|
|
8
|
Jiang XC and Gao JQ: Exosomes as novel
bio-carriers for gene and drug delivery. Int J Pharm. 521:167–175.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Wu L, Zhang X, Zhang B, Shi H, Yuan X, Sun
Y, Pan Z, Qian H and Xu W: Exosomes derived from gastric cancer
cells activate NF-κB pathway in macrophages to promote cancer
progression. Tumour Biol. 37:12169–12180. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhao B, Zhang Y, Han S, Zhang W, Zhou Q,
Guan H, Liu J, Shi J, Su L and Hu D: Exosomes derived from human
amniotic epithelial cells accelerate wound healing and inhibit scar
formation. J Mol Histol. 48:121–132. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Chen L, Wang Y, Pan Y, Zhang L, Shen C,
Qin G, Ashraf M, Weintraub N, Ma G and Tang Y: Cardiac
progenitor-derived exosomes protect ischemic myocardium from acute
ischemia/reperfusion injury. Biochem Biophys Res Commun.
431:566–571. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Virtakoivu R, Pellinen T, Rantala JK,
Perälä M and Ivaska J: Distinct roles of AKT isoforms in regulating
β1-integrin activity, migration, and invasion in prostate cancer.
Mol Biol Cell. 23:3357–3369. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Qu JL, Qu XJ, Zhao MF, Teng YE, Zhang Y,
Hou KZ, Jiang YH, Yang XH and Liu YP: Gastric cancer exosomes
promote tumour cell proliferation through PI3K/Akt and MAPK/ERK
activation. Dig Liver Dis. 41:875–880. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Malik ZA, Kott KS, Poe AJ, Kuo T, Chen L,
Ferrara KW and Knowlton AA: Cardiac myocyte exosomes: Stability,
HSP60, and proteomics. Am J Physiol Heart Circ Physiol.
304:H954–H965. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Hinescu ME, Gherghiceanu M, Suciu L and
Popescu LM: Telocytes in pleura: Two- and three-dimensional imaging
by transmission electron microscopy. Cell Tissue Res. 343:389–397.
2011. View Article : Google Scholar :
|
|
16
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
17
|
Zhang Y, Zheng Y, Faheem A, Sun T, Li C,
Li Z, Zhao D, Wu C and Liu J: A novel AKT inhibitor, AZD5363,
inhibits phosphorylation of AKT downstream molecules, and activates
phosphorylation of mTOR and SMG-1 dependent on the liver cancer
cell type. Oncol Lett. 11:1685–1692. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Hasson SP, Rubinek T, Ryvo L and Wolf I:
Endocrine resistance in breast cancer: Focus on the
phosphatidylinositol 3-kinase/akt/mammalian target of rapamycin
signaling pathway. Breast Care (Basel). 8:248–255. 2013. View Article : Google Scholar
|
|
19
|
Chimenti I, Smith RR, Li TS, Gerstenblith
G, Messina E, Giacomello A and Marbán E: Relative roles of direct
regeneration versus paracrine effects of human cardiosphere-derived
cells transplanted into infarcted mice. Circ Res. 106:971–980.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Le T and Chong J: Cardiac progenitor cells
for heart repair. Cell Death Discov. 2:160522016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Hergenreider E, Heydt S, Tréguer K,
Boettger T, Horrevoets AJ, Zeiher AM, Scheffer MP, Frangakis AS,
Yin X, Mayr M, et al: Atheroprotective communication between
endothelial cells and smooth muscle cells through miRNAs. Nat Cell
Biol. 14:249–256. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
22
|
Bang C, Batkai S, Dangwal S, Gupta SK,
Foinquinos A, Holzmann A, Just A, Remke J, Zimmer K, Zeug A, et al:
Cardiac fibroblast-derived microRNA passenger strand-enriched
exosomes mediate cardiomyocyte hypertrophy. J Clin Invest.
124:2136–2146. 2014. View
Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kapustin AN, Chatrou ML, Drozdov I, Zheng
Y, Davidson SM, Soong D, Furmanik M, Sanchis P, De Rosales RT,
Alvarez-Hernandez D, et al: Vascular smooth muscle cell
calcification is mediated by regulated exosome secretion. Circ Res.
116:1312–1323. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Beltrami C, Besnier M, Shantikumar S,
Shearn AI, Rajakaruna C, Laftah A, Sessa F, Spinetti G, Petretto E,
Angelini GD and Emanueli C: Human pericardial fluid contains
exosomes enriched with cardiovascular-expressed MicroRNAs and
promotes therapeutic angiogenesis. Mol Ther. 25:679–693. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Pironti G, Strachan RT, Abraham D, Mon-Wei
Yu S, Chen M, Chen W, Hanada K, Mao L, Watson LJ and Rockman HA:
Circulating exosomes induced by cardiac pressure overload contain
functional angiotensin II type 1 receptors. Circulation.
131:2120–2130. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhang J, Ma J, Long K, Qiu W, Wang Y, Hu
Z, Liu C, Luo Y, Jiang A, Jin L, et al: Overexpression of exosomal
cardioprotective miRNAs mitigates hypoxia-induced H9c2 cells
apoptosis. Int J Mol Sci. 18:E7112017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Cui X, He Z, Liang Z, Chen Z, Wang H and
Zhang J: Exosomes from adipose-derived mesenchymal stem cells
protect ischemic myocardium from ischemia/reperfusion injury via
Wnt/β-catenin signaling pathway. J Cardiovasc Pharmacol.
70:225–231. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Shao L, Zhang Y, Lan B, Wang J, Zhang Z,
Zhang L, Xiao P, Meng Q, Geng YJ, Yu XY and Li Y: MiRNA-sequence
indicates that mesenchymal stem cells and exosomes have similar
mechanism to enhance cardiac repair. Biomed Res Int.
2017:41507052017. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Xiao J, Pan Y, Li XH, Yang XY, Feng YL,
Tan HH, Jiang L, Feng J and Yu XY: Cardiac progenitor cell-derived
exosomes prevent cardiomyocytes apoptosis through exosomal miR-21
by targeting PDCD4. Cell Death Dis. 7:e22772016. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Peltier J, O'Neill A and Schaffer DV:
PI3K/Akt and CREB regulate adult neural hippocampal progenitor
proliferation and differentiation. Dev Neurobiol. 67:1348–1361.
2007. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Latronico MV, Costinean S, Lavitrano ML,
Peschle C and Condorelli G: Regulation of cell size and contractile
function by AKT in cardiomyocytes. Ann N Y Acad Sci. 1015:250–260.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Li Q, Shen L, Wang Z, Jiang HP and Liu LX:
Tanshinone IIA protects against myocardial ischemia reperfusion
injury by activating the PI3K/Akt/mTOR signaling pathway. Biomed
Pharmacother. 84:106–114. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Campenot RB: Local control of neurite
development by nerve growth factor. Proc Natl Acad Sci USA.
74:4516–4519. 1977. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zhang J, Wang C, Yu S, Luo Z, Chen Y, Liu
Q, Hua F, Xu G and Yu P: Sevoflurane postconditioning protects rat
hearts against ischemia-reperfusion injury via the activation of
PI3K/AKT/mTOR signaling. Sci Rep. 4:73172014. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Wang ZG, Wang Y, Huang Y, Lu Q, Zheng L,
Hu D, Feng WK, Liu YL, Ji KT, Zhang HY, et al: bFGF regulates
autophagy and ubiquitinated protein accumulation induced by
myocardial ischemia/reperfusion via the activation of the
PI3K/Akt/mTOR pathway. Sci Rep. 5:92872015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Han D, Wan C, Liu F, Xu X, Jiang L and Xu
J: Jujuboside a protects H9C2 cells from isoproterenol-induced
injury via activating PI3K/Akt/mTOR signaling pathway. Evid Based
Complement Alternat Med. 2016:95937162016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Leithe E and Rivedal E: Ubiquitination and
down-regulation of gap junction protein connexin-43 in response to
12-O-tetradecanoylphorbol 13-acetate treatment. J Biol Chem.
279:50089–50096. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Ke Z, Wang G, Yang L, Qiu H, Wu H, Du M,
Chen J, Song J, Jia X and Feng L: Crude terpene glycoside component
from Radix paeoniae rubra protects against isoproterenol-induced
myocardial ischemic injury via activation of the PI3K/AKT/mTOR
signaling pathway. J Ethnopharmacol. 206:160–169. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Yu W, Sun H, Zha W, Cui W, Xu L, Min Q and
Wu J: Apigenin attenuates adriamycin-induced cardiomyocyte
apoptosis via the PI3K/AKT/mTOR pathway. Evid Based Complement
Alternat Med. 2017:25906762017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Cui J, Zhang F, Wang Y, Liu J, Ming X, Hou
J, Lv B, Fang S and Yu B: Macrophage migration inhibitory factor
promotes cardiac stem cell proliferation and endothelial
differentiation through the activation of the PI3K/Akt/mTOR and
AMPK pathways. Int J Mol Med. 37:1299–1309. 2016. View Article : Google Scholar : PubMed/NCBI
|
