Journal Articles
Review
Prostaglandin EP2 receptor: Novel therapeutic target for human cancers (Review)
Xiaoting Sun, Qi Li
Pages: 1203-1214 Published online on: 26 June 2018
Article
Histone modifications in fatty acid synthase modulated by carbohydrate responsive element binding protein are associated with non‑alcoholic fatty liver disease
Can Cai, Huihong Yu, Guangming Huang, Xuan Du, Xiaoqing Yu, Youping Zhou, Wei Shen
Pages: 1215-1228 Published online on: 22 May 2018
Article
miR‑215 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer
Xiaoxu Gao, Yan Cai, Ruifang An
Pages: 1229-1236 Published online on: 22 May 2018
Article
Construction and analysis of a ceRNA‑ceRNA network reveals two potential prognostic modules regulated by hsa‑miR‑335‑5p in osteosarcoma
Yuxi Chen, Qinghe Chen, Jilong Zou, Yan Zhang, Zhenggang Bi
Pages: 1237-1246 Published online on: 29 May 2018
Article
CDMP1 overexpression mediates inflammatory cytokine‑induced apoptosis via inhibiting the Wnt/β‑Catenin pathway in rat dorsal root ganglia neurons
Zhongwei Jia, Yingang Zhang, Yunxing Su, Xiaojian Wang, Jianping Yu, Qiling Yuan, Liang Liu
Pages: 1247-1256 Published online on: 05 June 2018
Article
Inhibition of osteoclastogenesis for periprosthetic osteolysis therapy through the suppression of p38 signaling by fraxetin
Jia‑Cheng Liao, Zhao‑Xia Wei, Chang Zhao, Zhong‑Ping Ma, Dao‑Zhang Cai
Pages: 1257-1264 Published online on: 21 May 2018
Article
Long noncoding RNA myocardial infarction‑associated transcript is associated with the microRNA‑150‑5p/P300 pathway in cardiac hypertrophy
Zhao Li, Yamin Liu, Xiaofan Guo, Guozhe Sun, Qun Ma, Ying Dai, Guangshuo Zhu, Yingxian Sun
Pages: 1265-1272 Published online on: 21 May 2018
Article
Preparation and evaluation of spirulina polysaccharide nanoemulsions
Bingyue Wang, Tiange Cai, Qian Liu, John Cameron Cole Whitney, Manling Du, Qianqian Ma, Ronghua Zhang, Li Yang, Susan P.C. Cole, Yu Cai
Pages: 1273-1282 Published online on: 05 June 2018
Article
Telomerase reverse transcriptase interference synergistically promotes tumor necrosis factor‑related apoptosis‑inducing ligand‑induced oral squamous cell carcinoma apoptosis and suppresses proliferation in vitro and in vivo
Xin Zhao, Cuicui Zhang, Zhiliang Le, Suyun Zeng, Chaobin Pan, Jianjie Shi, Jianguang Wang, Xiaopeng Zhao
Pages: 1283-1294 Published online on: 07 June 2018
Article
Artesunate induces apoptosis and autophagy in HCT116 colon cancer cells, and autophagy inhibition enhances the artesunate‑induced apoptosis
Feng Jiang, Jin‑Yong Zhou, Dan Zhang, Ming‑Hao Liu, Yu‑Gen Chen
Pages: 1295-1304 Published online on: 01 June 2018
Article
Exclusive enteral nutrition protects against inflammatory bowel disease by inhibiting NF‑κB activation through regulation of the p38/MSK1 pathway
Ting Yu, Qian Yu, Xiaotian Chen, Lixing Zhou, Yuming Wang, Chenggong Yu
Pages: 1305-1316 Published online on: 04 June 2018
Article
miR‑6835‑3p regulates the function of pancreatic islet cells by modulating the expression of AdipoR1
Huimin Wang, Lei Jiang, Zhenfu Li, Wei Wang, Chuanji Hao
Pages: 1317-1326 Published online on: 15 June 2018
Article
Nrf2 protects against diabetic dysfunction of endothelial progenitor cells via regulating cell senescence
Rui‑Yun Wang, Li‑Hua Liu, Hongxia Liu, Ke‑Fei Wu, Jing An, Qian Wang, Yun Liu, Li‑Juan Bai, Ben‑Ming Qi, Ben‑Ling Qi, Lei Zhang
Pages: 1327-1340 Published online on: 11 June 2018
Article
Fasudil preserves lung endothelial function and reduces pulmonary vascular remodeling in a rat model of end‑stage pulmonary hypertension with left heart disease
Rulin Zhuang, Jinfu Wu, Fang Lin, Lu Han, Xiaoting Liang, Qingshu Meng, Yuyu Jiang, Zhulin Wang, Aixue Yue, Yuying Gu, Huimin Fan, Xiaohui Zhou, Zhongmin Liu
Pages: 1341-1352 Published online on: 13 June 2018
Article
Characteristics of circular RNA expression in lung tissues from mice with hypoxia‑induced pulmonary hypertension
Jian Wang, Meng‑Chan Zhu, Bill Kalionis, Jun‑Zhen Wu, Lin‑Lin Wang, Hai‑Yan Ge, Cui‑Cui Chen, Xiao‑Dan Tang, Yuan‑Lin Song, Hong He, Shi‑Jin Xia
Pages: 1353-1366 Published online on: 21 June 2018
Article
MicroRNA‑26a protects vascular smooth muscle cells against H2O2‑induced injury through activation of the PTEN/AKT/mTOR pathway
Junlu Peng, Xinqi He, Lei Zhang, Peng Liu
Pages: 1367-1378 Published online on: 27 June 2018
Article
Protective effect of morin on myocardial ischemia‑reperfusion injury in rats
Shuang Liu, Nan Wu, Jiaxin Miao, Zijun Huang, Xuying Li, Pengyu Jia, Yuxuan Guo, Dalin Jia
Pages: 1379-1390 Published online on: 26 June 2018
Article
Reversal of the Warburg effect with DCA in PDGF‑treated human PASMC is potentiated by pyruvate dehydrogenase kinase‑1 inhibition mediated through blocking Akt/GSK‑3β signalling
Bingbing Li, Yuling Zhu, Qing Sun, Chunfang Yu, Lian Chen, Yali Tian, Jie Yan
Pages: 1391-1400 Published online on: 27 June 2018
Article
p38 mitogen-activated protein kinase gene silencing rescues rat hippocampal neurons from ketamine-induced apoptosis: An in vitro study
Xiao‑Qian Guo, Yu‑Ling Cao, Li Zhao, Xuan Zhang, Zhong‑Rui Yan, Wei‑Mei Chen
Pages: 1401-1410 Published online on: 29 June 2018
Article
Kushui Rose (R. Setate x R. Rugosa) decoction exerts antitumor effects in C. elegans by downregulating Ras/MAPK pathway and resisting oxidative stress
Yan Liu, Dejuan Zhi, Xin Wang, Dongqing Fei, Zhanxin Zhang, Zhengrong Wu, Yang Li, Peng Chen, Hongyu Li
Pages: 1411-1417 Published online on: 21 June 2018
Article
Sox2 promotes tumor aggressiveness and epithelial‑mesenchymal transition in tongue squamous cell carcinoma
Xingguang Liu, Bin Qiao, Tengda Zhao, Fengchun Hu, Alfred King‑Yin Lam, Qian Tao
Pages: 1418-1426 Published online on: 26 June 2018
Article
Resveratrol induced reactive oxygen species and endoplasmic reticulum stress‑mediated apoptosis, and cell cycle arrest in the A375SM malignant melanoma cell line
Jae‑Rim Heo, Soo‑Min Kim, Kyung‑A Hwang, Ji‑Houn Kang, Kyung‑Chul Choi
Pages: 1427-1435 Published online on: 15 June 2018
Article
Regulation of TLR4 expression mediates the attenuating effect of erythropoietin on inflammation and myocardial fibrosis in rat heart
Fei Liu, Yuan Wen, Jinyuan Kang, Chunying Wei, Menghong Wang, Zeqi Zheng, Jingtian Peng
Pages: 1436-1444 Published online on: 25 May 2018
Article
Liquiritin suppresses UVB‑induced skin injury through prevention of inflammation, oxidative stress and apoptosis through the TLR4/MyD88/NF‑κB and MAPK/caspase signaling pathways
Xiao‑Qing Li, Li‑Min Cai, Jing Liu, Yan‑Li Ma, Ying‑Hui Kong, He Li, Ming Jiang
Pages: 1445-1459 Published online on: 05 June 2018
Article
Linarin prevents LPS‑induced acute lung injury by suppressing oxidative stress and inflammation via inhibition of TXNIP/NLRP3 and NF‑κB pathways
Xiang Han, Yi‑Chen Wu, Min Meng, Qing‑Song Sun, Su‑Min Gao, Hong Sun
Pages: 1460-1472 Published online on: 30 May 2018
Article
Paeonol induces the apoptosis of the SGC‑7901 gastric cancer cell line by downregulating ERBB2 and inhibiting the NF‑κB signaling pathway
Jun Fu, Luhua Yu, Jie Luo, Rui Huo, Bing Zhu
Pages: 1473-1483 Published online on: 23 May 2018
Article
IL‑1β and TNF‑α suppress TGF‑β‑promoted NGF expression in periodontal ligament‑derived fibroblasts through inactivation of TGF‑β‑induced Smad2/3‑ and p38 MAPK‑mediated signals
Maiko Ohta, Naoyuki Chosa, Seiko Kyakumoto, Seiji Yokota, Naoto Okubo, Akira Nemoto, Masaharu Kamo, Shigeharu Joh, Kenichi Satoh, Akira Ishisaki
Pages: 1484-1494 Published online on: 04 June 2018
Article
A novel scoring system for acute myeloid leukemia risk assessment based on the expression levels of six genes
Xiaoyan Zhao, Yuan Li, Haibing Wu
Pages: 1495-1507 Published online on: 21 June 2018
Article
Hypoxia‑induced expression of CXCR4 favors trophoblast cell migration and invasion via the activation of HIF‑1α
Zhan Zhang, Pengyun Li, Yan Wang, Huan Yan
Pages: 1508-1516 Published online on: 22 May 2018
Article
Cardiac progenitor cell‑derived exosomes promote H9C2 cell growth via Akt/mTOR activation
Shentang Li, Jie Jiang, Zuocheng Yang, Zhuoying Li, Xing Ma, Xin Li
Pages: 1517-1525 Published online on: 21 May 2018
Article
Proliferation and differentiation of rat adipose‑derived stem cells are regulated by yes‑associated protein
Xingzhi Jing, Jiang Wang, Weifeng Yin, Guanghui Li, Zhong Fang, Wentao Zhu, Fengjing Guo, Yaping Ye
Pages: 1526-1536 Published online on: 18 June 2018
Article
miRNA‑145 inhibits myocardial infarction‑induced apoptosis through autophagy via Akt3/mTOR signaling pathway in vitro and in vivo
Liqiu Yan, Nan Guo, Yanchao Cao, Saitian Zeng, Jiawang Wang, Fengfeng Lv, Yunfei Wang, Xufen Cao
Pages: 1537-1547 Published online on: 28 June 2018
Article
Downregulation of aquaporin 9 decreases catabolic factor expression through nuclear factor‑κB signaling in chondrocytes
Kazuhiro Takeuchi, Shinya Hayashi, Tomoyuki Matumoto, Shingo Hashimoto, Koji Takayama, Nobuaki Chinzei, Shinsuke Kihara, Masahiko Haneda, Shinsuke Kirizuki, Yuichi Kuroda, Masanori Tsubosaka, Kotaro Nishida, Ryosuke Kuroda
Pages: 1548-1558 Published online on: 13 June 2018
Article
Overexpression of miR‑17‑5p protects against high glucose‑induced endothelial cell injury by targeting E2F1‑mediated suppression of autophagy and promotion of apoptosis
Yifeng Yuan, Xue Li, Maoquan Li
Pages: 1559-1568 Published online on: 21 May 2018
Article
Plumbagin, a natural naphthoquinone, inhibits the growth of esophageal squamous cell carcinoma cells through inactivation of STAT3
Yan Cao, Xiang Yin, Yiping Jia, Bingyan Liu, Shaoqiu Wu, Mingyi Shang
Pages: 1569-1576 Published online on: 07 June 2018
Article
MicroRNA‑155 contributes to the occurrence of epilepsy through the PI3K/Akt/mTOR signaling pathway
Wei Duan, Yan Chen, Xiao‑Rong Wang
Pages: 1577-1584 Published online on: 01 June 2018
Article
MicroRNA‑155 targets myosin light chain kinase to inhibit the migration of human bone marrow‑derived mesenchymal stem cells
Xingbing Wang, Xu Ye, Jingjuan Ji, Jian Wang, Bo Xu, Qian Zhang, Jing Ming, Xin Liu
Pages: 1585-1592 Published online on: 05 June 2018
Article
Loss of KLF15 accelerates chronic podocyte injury
Seung Seok Han, Mi‑Yeon Yu, Kyung Don Yoo, Jung Pyo Lee, Dong Ki Kim, Yon Su Kim, Seung Hee Yang
Pages: 1593-1602 Published online on: 11 June 2018
Article
Targeted resequencing of phosphorus metabolism‑related genes in 86 patients with hypophosphatemic rickets/osteomalacia
Jiemei Gu, Chun Wang, Hao Zhang, Hua Yue, Weiwei Hu, Jinwei He, Wenzhen Fu, Zhenlin Zhang
Pages: 1603-1614 Published online on: 13 June 2018
Article
Exposure to EGF and 17β‑estradiol irreversibly affects the proliferation and transformation of MCF7 cells but is not sufficient to promote tumor growth in a xenograft mouse model upon withdrawal of exposure
Sara I. Cunha, Min Jia, Serhiy Souchelnytskyi
Pages: 1615-1624 Published online on: 20 June 2018
Article
Quercetin‑3‑methyl ether suppresses human breast cancer stem cell formation by inhibiting the Notch1 and PI3K/Akt signaling pathways
Longbin Cao, Yunxiao Yang, Ziyu Ye, Bihua Lin, Jincheng Zeng, Caihong Li, Tong Liang, Keyuan Zhou, Jixia Li
Pages: 1625-1636 Published online on: 25 June 2018
Article
Dysregulation of microRNA‑23b‑3p contributes to the development of intracranial aneurysms by targeting phosphatase and tensin homolog
Dong Guo, Ye‑Wei Wang, Lei Yan, Ji Ma, Xin‑Wei Han, Shao‑Feng Shui
Pages: 1637-1643 Published online on: 25 May 2018
Article
Mitochondrial dysfunction induces the invasive phenotype, and cell migration and invasion, through the induction of AKT and AMPK pathways in lung cancer cells
Si‑Yoon Han, Yun‑Jeong Jeong, Yongsoo Choi, Soon‑Kyung Hwang, Young‑Seuk Bae, Young‑Chae Chang
Pages: 1644-1652 Published online on: 18 June 2018
Article
Increased expression of CHOP and LC3B in newborn rats with bronchopulmonary dysplasia
Mengyun Li, Bingting Pan, Yongyan Shi, Jianhua Fu, Xindong Xue
Pages: 1653-1665 Published online on: 08 June 2018
Article
Suppressive effects of Wang‑Bi Tablet on adjuvant‑induced arthritis in rats via NF‑κB and STAT3 signaling pathways
Yun‑Yun Guan, Yeqing Zhang, Li‑Xin Liu, Hai‑Dong Li, Dan Xue, Wei‑Lian Bao, Guan Ye, Xiaoyan Shen
Pages: 1666-1674 Published online on: 08 June 2018
Article
TERT promoter hypermethylation is associated with poor prognosis in adrenocortical carcinoma
Fredrika Svahn, Johan O. Paulsson, Adam Stenman, Omid Fotouhi, Ninni Mu, Timothy D. Murtha, Reju Korah, Tobias Carling, Martin Bäckdahl, Na Wang, C. Christofer Juhlin, Catharina Larsson
Pages: 1675-1683 Published online on: 20 June 2018
Article
FGF21 attenuates hypoxia‑induced dysfunction and apoptosis in HPAECs through alleviating endoplasmic reticulum stress
Ali Chen, Jingjing Liu, Jianfeng Zhu, Xuetao Wang, Zhaona Xu, Zhimin Cui, Dan Yao, Zhifeng Huang, Min Xu, Mayun Chen, Peiliang Wu, Manxiang Li, Liangxing Wang, Xiaoying Huang
Pages: 1684-1694 Published online on: 24 May 2018
Article
Sequence‑dependent effect of sorafenib in combination with natural phenolic compounds on hepatic cancer cells and the possible mechanism of action
Abdulmajeed A. Bahman, Mohamed Salah I. Abaza, Sarah I. Khoushiash, Rajaa J. Al‑Attiyah
Pages: 1695-1715 Published online on: 08 June 2018
Article
AQP4‑knockout alleviates the lipopolysaccharide‑induced inflammatory response in astrocytes via SPHK1/MAPK/AKT signaling
Wangshu Dai, Junjun Yan, Guangzong Chen, Gang Hu, Xiqiao Zhou, Xiaoning Zeng
Pages: 1716-1722 Published online on: 29 June 2018
Article
Farnesoid X receptor agonist decreases lipid accumulation by promoting hepatic fatty acid oxidation in db/db mice
Yujie Liu, An Song, Xi Yang, Yunfeng Zhen, Weiwei Chen, Linquan Yang, Chao Wang, Huijuan Ma
Pages: 1723-1731 Published online on: 05 June 2018
Article
Apelin‑13 attenuates ER stress‑associated apoptosis induced by MPP+ in SH‑SY5Y cells
Yunlu Jiang, Haiqing Liu, Bingyuan Ji, Zhengwen Wang, Chunmei Wang, Chunqing Yang, Yanyou Pan, Jing Chen, Baohua Cheng, Bo Bai
Pages: 1732-1740 Published online on: 05 June 2018
Article
Regulatory effects of the long non‑coding RNA RP11‑543N12.1 and microRNA‑324‑3p axis on the neuronal apoptosis induced by the inflammatory reactions of microglia
Miao Cai, Yan‑Wen Wang, Shan‑Hu Xu, Song Qiao, Qin‑Fen Shu, Jian‑Zong Du, Ya‑Guo Li, Xiao‑Li Liu
Pages: 1741-1755 Published online on: 20 June 2018
Article
GDF‑15 prevents LPS and D‑galactosamine‑induced inflammation and acute liver injury in mice
Min Li, Kui Song, Xiaowen Huang, Simao Fu, Qiyi Zeng
Pages: 1756-1764 Published online on: 27 June 2018
Correction
