|
1
|
Mclnnes IB and Schett G: The pathogenesis
of rheumatoid arthritis. N Engl J Med. 365:2205–2219. 2011.
View Article : Google Scholar
|
|
2
|
Glant TT, Mikecz K and Rauch TA:
Epigenetics in the pathogenesis of rheumatoid arthritis. BMC Med.
12:352014. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Dougados M, Soubrier M, Antunez A, Balint
P, Balsa A, Buch MH, Casado G, Detert J, El-Zorkany B, Emery P, et
al: Prevalence of comorbidities in rheumatoid arthritis and
evaluation of their monitoring: Results of an international,
cross-sectional study (COMORA). Ann Rheum Dis. 73:62–68. 2014.
View Article : Google Scholar :
|
|
4
|
Gabriel SE, Crowson CS, Kremers HM, Doran
MF, Turesson C, O'Fallon WM and Matteson EL: Survival in rheumatoid
arthritis: A population-based analysis of trends over 40 years.
Arthritis Rheum. 48:54–58. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Kobelt G and Jönsson B: The burden of
rheumatoid arthritis and access to treatment: outcome and
cost-utility of treatments. Eur J Health Econ. 8(Suppl 2):
S95–S106. 2008. View Article : Google Scholar
|
|
6
|
Guo Q, Wang Y, Xu D, Nossent J, Pavlos NJ
and Xu J: Rheumatoid arthritis: Pathological mechanisms and modern
pharmacologic therapies. Bone Res. 6:152018. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Boechat Nde O, Ogusku MM, Boechat AL and
Sadahiro A: Interaction between smoking and HLA-DRB1*04 gene is
associated with a high cardiovascular risk in Brazilian Amazon
patients with rheumatoid arthritis. PLoS One. 7:e415882012.
View Article : Google Scholar
|
|
8
|
Bartok B and Firestein GS: Fibroblast-like
synoviocytes: Key effector cells in rheumatoid arthritis. Immunol
Rev. 233:233–255. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Konisti S, Kiriakidis S and Paleolog EM:
Hypoxia - a key regulator of angiogenesis and inflammation in
rheumatoid arthritis. Nat Rev Rheumatol. 8:153–162. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tang Q, Cui J, Tian Z, Sun J, Wang Z,
Chang S and Zhu S: Oxygen and indocyanine green loaded
phase-transition nanoparticle-mediated photo-sonodynamic cytotoxic
effects on rheumatoid arthritis fibroblast-like synoviocytes. Int J
Nanomedicine. 12:381–393. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Duxbury MS, Ito H, Zinner MJ, Ashley SW
and Whang EE: RNA interference targeting the M2 subunit of
ribonucleotide reductase enhances pancreatic adenocarcinoma
chemosensitivity to gemcitabine. Oncogene. 23:1539–1548. 2004.
View Article : Google Scholar
|
|
12
|
Zhang K, Hu S, Wu J, Chen L, Lu J, Wang X,
Liu X, Zhou B and Yen Y: Overexpression of RRM2 decreases
thrombspondin-1 and increases VEGF production in human cancer cells
in vitro and in vivo: Implication of RRM2 in angiogenesis. Mol
Cancer. 8:112009. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Shao J, Zhou B, Chu B and Yen Y:
Ribonucleotide reductase inhibitors and future drug design. Curr
Cancer Drug Targets. 6:409–431. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Gao J, Chen H, Yu Y, Song J, Song H, Su X,
Li W, Tong X, Qian W, Wang H, et al: Inhibition of hepatocellular
carcinoma growth using immunoliposomes for co-delivery of
adriamycin and ribonucleotide reductase M2 siRNA. Biomaterials.
34:10084–10098. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Roman-Blas JA and Jimenez SA: NF-kappaB as
a potential therapeutic target in osteoarthritis and rheumatoid
arthritis. Osteoarthritis Cartilage. 14:839–848. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Tomita T, Takeuchi E, Tomita N, Morishita
R, Kaneko M, Yamamoto K, Nakase T, Seki H, Kato K, Kaneda Y, et al:
Suppressed severity of collagen-induced arthritis by in vivo
transfection of nuclear factor kappaB decoy oligodeoxynucleotides
as a gene therapy. Arthritis Rheum. 42:2532–2542. 1999. View Article : Google Scholar
|
|
17
|
Gao J, Liu W, Xia Y, Li W, Sun J, Chen H,
Li B, Zhang D, Qian W, Meng Y, et al: The promotion of siRNA
delivery to breast cancer overexpressing epidermal growth factor
receptor through anti-EGFR antibody conjugation by immunoliposomes.
Biomaterials. 32:3459–3470. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Gao J, Yu Y, Zhang Y, Song J, Chen H, Li
W, Qian W, Deng L, Kou G, Chen J, et al: EGFR-specific PEGylated
immunoliposomes for active siRNA delivery in hepatocellular
carcinoma. Biomaterials. 33:270–282. 2012. View Article : Google Scholar
|
|
19
|
Gao J, Sun J, Li H, Liu W, Zhang Y, Li B,
Qian W, Wang H, Chen J and Guo Y: Lyophilized HER2-specific
PEGylated immunoliposomes for active siRNA gene silencing.
Biomaterials. 31:2655–2664. 2010. View Article : Google Scholar
|
|
20
|
Xu C, Lee SA and Chen X: RNA interference
as therapeutics for hepatocellular carcinoma. Recent Pat Anticancer
Drug Discov. 6:106–115. 2011. View Article : Google Scholar
|
|
21
|
Gao H, Zhang Q, Yu Z and He Q:
Cell-penetrating peptide-based intelligent liposomal systems for
enhanced drug delivery. Curr Pharm Biotechnol. 15:210–219. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Koren E and Torchilin VP: Cell-penetrating
peptides: Breaking through to the other side. Trends Mol Med.
18:385–393. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Jha D, Mishra R, Gottschalk S, Wiesmüller
KH, Ugurbil K, Maier ME and Engelmann J: CyLoP-1: A novel
cysteine-rich cell-penetrating peptide for cytosolic delivery of
cargoes. Bioconjug Chem. 22:319–328. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2−ΔΔC T method. Methods. 25:402–408.
2001. View Article : Google Scholar
|
|
25
|
Srirangan S and Choy EH: The role of
interleukin-6 in the pathophysiology of rheumatoid arthritis. Ther
Adv Musculoskelet Dis. 2:247–256. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Alonso-Ruiz A, Pijoan JI, Ansuategui E,
Urkaregi A, Calabozo M and Quintana A: Tumor necrosis factor alpha
drugs in rheumatoid arthritis: Systematic review and metaanalysis
of efficacy and safety. BMC Musculoskelet Disord. 9:522008.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Lee H, Lytton-Jean AK, Chen Y, Love KT,
Park AI, Karagiannis ED, Sehgal A, Querbes W, Zurenko CS, Jayaraman
M, et al: Molecularly self-assembled nucleic acid nanoparticles for
targeted in vivo siRNA delivery. Nat Nanotechnol. 7:389–393. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Tseng YC, Mozumdar S and Huang L:
Lipid-based systemic delivery of siRNA. Adv Drug Deliv Rev.
61:721–731. 2009. View Article : Google Scholar : PubMed/NCBI
|
