|
1
|
Ajani JA: Evolving chemotherapy for
advanced gastric cancer. Oncologist. 3(Suppl 10): 49–58. 2005.
View Article : Google Scholar
|
|
2
|
Gou WF, Shen DF, Yang XF, Zhao S, Liu YP,
Sun HZ, Su RJ, Luo JS and Zheng HC: ING5 suppresses proliferation,
apoptosis, migration and invasion, and induces autophagy and
differentiation of gastric cancer cells: A good marker for
carcinogenesis and subsequent progression. Oncotarget.
6:19552–19579. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Fioroni I, Dell'aquila E, Pantano F,
Intagliata S, Caricato M, Vincenzi B, Coppola R, Santini D and
Tonini G: Role of c-mesenchymal-epithelial transition pathway in
gastric cancer. Expert Opin Pharmacother. 16:1195–1207. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Nieto MA, Huang RY, Jackson RA and Thiery
JP: EMT: 2016. Cell. 166:21–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Peng Z, Wang CX, Fang EH, Wang GB and Tong
Q: Role of epithelial-mesenchymal transition in gastric cancer
initiation and progression. World J Gastroenterol. 20:5403–5410.
2014. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK,
Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW and Koh YW: Hypoxia
induces epithelial-mesenchymal transition in follicular thyroid
cancer: Involvement of regulation of twist by hypoxia inducible
factor-1α. Yonsei Med J. 56:1503–1514. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Guo J, Wang B, Fu Z, Wei J and Lu W:
Hypoxic microenvironment induces EMT and upgrades stem-like
properties of gastric cancer cells. Technol Cancer Res Treat.
15:60–68. 2016. View Article : Google Scholar
|
|
8
|
Tian M, Neil JR and Schiemann WP:
Transforming growth factor-β and the hallmarks of cancer. Cell
Signal. 23:951–962. 2011. View Article : Google Scholar
|
|
9
|
Kasashima H, Yashiro M, Kinoshita H,
Fukuoka T, Morisaki T, Masuda G, Sakurai K, Kubo N, Ohira M and
Hirakawa K: Lysyl oxidase is associated with the
epithelial-mesenchymal transition of gastric cancer cells in
hypoxia. Gastric Cancer. 19:431–442. 2016. View Article : Google Scholar
|
|
10
|
Leng A, Liu T, He Y, Li Q and Zhang G:
Smad4/Smad7 balance: A role of tumorigenesis in gastric cancer. Exp
Mol Pathol. 87:48–53. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Noda S, Yashiro M, Nshii T and Hirakawa K:
Hypoxia upregulates adhesion ability to peritoneum through a
transforming growth factor-beta-dependent mechanism in diffuse-type
gastric cancer cells. Eur J Cancer. 46:995–1005. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Taylor MA, Amin JD, Kirschmann DA and
Schiemann WP: Lysyl oxidase contributes to
mechanotransduction-mediated regulation of transforming growth
factor-β signaling in breast cancer cells. Neoplasia. 13:406–418.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Oskarsson T: Extracellular matrix
components in breast cancer progression and metastasis. Breast.
2(Suppl 22): S66–S72. 2013. View Article : Google Scholar
|
|
14
|
Barry-Hamilton V, Spangler R, Marshall D,
McCauley S, Rodriguez HM, Oyasu M, Mikels A, Vaysberg M, Ghermazien
H, Wai C, et al: Allosteric inhibition of lysyl oxidase-like-2
impedes the development of a pathologic microenvironment. Nat Med.
16:1009–1017. 2010. View
Article : Google Scholar : PubMed/NCBI
|
|
15
|
Cuevas EP, Moreno-Bueno G, Canesin G,
Santos V, Portillo F and Cano A: LOXL2 catalytically inactive
mutants mediate epithelial-to-mesenchymal transition. Biol Open.
3:129–137. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Erler JT, Bennewith KL, Nicolau M,
Dornhöfer N, Kong C, Le QT, Chi JT, Jeffrey SS and Giaccia AJ:
Lysyl oxidase is essential for hypoxia-induced metastasis. Nature.
440:1222–1226. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Matsuoka J, Yashiro M, Doi Y, Fuyuhiro Y,
Kato Y, Shinto O, Noda S, Kashiwagi S, Aomatsu N, Hirakawa T, et
al: Hypoxia stimulates the EMT of gastric cancer cells through
autocrine TGFβ signaling. PLoS One. 8:e623102013. View Article : Google Scholar
|
|
18
|
Zhu J, Huang S, Wu G, Huang C, Li X, Chen
Z, Zhao L and Zhao Y: Lysyl oxidase is predictive of unfavorable
outcomes and essential for regulation of vascular endothelial
growth factor in hepatocellular carcinoma. Dig Dis Sci.
60:3019–3031. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lai H, Jin Q, Lin Y, Mo X, Li B, He K and
Chen J: Combined use of lysyl oxidase, carcino-embryonic antigen,
and carbohydrate antigens improves the sensitivity of biomarkers in
predicting lymph node metastasis and peritoneal metastasis in
gastric cancer. Tumour Biol. 35:10547–10554. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Xu Y, Jin X, Huang Y, Dong J, Wang H, Wang
X and Cao X: Inhibition of peritoneal metastasis of human gastric
cancer cells by dextran sulphate through the reduction in HIF-1α
and ITGβ1 expression. Oncol Rep. 35:2624–2634. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Waddell T, Verheij M, Allum W, Cunningham
D, Cervantes A and Arnold D: Gastric cancer: ESMO-esso-estro
clinical practice guidelines for diagnosis, treatment and
follow-up. Radiother Oncol. 110:189–194. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yang X, Li S, Li W, Chen J, Xiao X, Wang
Y, Yan G and Chen L: Inactivation of lysyl oxidase by
β-aminopropionitrile inhibits hypoxia-induced invasion and
migration of cervical cancer cells. Oncol Rep. 29:541–548. 2013.
View Article : Google Scholar
|
|
23
|
Ding W, Zhang W, Hui FM, Zhang YH, Zhang
FF, Li XM and Shi FX: Cell-specific expression and
immunolocalization of nitric oxide synthase isoforms and soluble
guanylyl cyclase α1 and β1 subunits in the ovary of fetal, neonatal
and immature pigs. Anim Reprod Sci. 131:172–180. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Riquelme I, Saavedra K, Espinoza J A,
Weber H, García P, Nervi B, Garrido M, Corvalán AH, Roa JC and
Bizama C: Molecular classification of gastric cancer: Towards a
pathway-driven targeted therapy. Oncotarget. 6:24750–24779. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Gordan JD and Simon MC: Hypoxia-inducible
factors: Central regulators of the tumor phenotype. Curr opin Genet
Dev. 17:71–77. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Hagiwara A, Sakakura C, Shirasu M, Togawa
T, Sonoyama Y, Fujiyama J, Ebihara Y, Itoh T and Yamagishi H:
Intraperitoneal injection of dextran sulfate as an anti-adherent
drug for the prevention of peritoneal metastasis of cancer shows
low toxicity in animals. Anticancer Drugs. 11:393–399. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kawamura N, Sun-Wada GH, Aoyama M, Harada
A, Takasuga S, Sasaki T and Wada Y: Delivery of endosomes to
lysosomes via microautophagy in the visceral endoderm of mouse
embryos. Nat Commun. 3:10712012. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Erez N: Cancer: Opening lox to metastasis.
Nature. 522:41–42. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Vaupel P and Harrison L: Tumor hypoxia:
Causative factors, compensatory mechanisms, and cellular response.
Oncologist. 5(Suppl 9): S4–S9. 2004. View Article : Google Scholar
|
|
30
|
Wang Y, Ma J, Shen H, Wang C, Sun Y,
Howell SB and Lin X: Reactive oxygen species promote ovarian cancer
progression via the HIF-1α/LOX/E-cadherin pathway. Oncol Rep.
32:2150–2158. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Lim S, Bae E, Kim HS, Kim TA, Byun K, Kim
B, Hong S, Im JP, Yun C, Lee B, et al: TRAF6 mediates
IL-1β/LPS-induced suppression of TGF-β signaling through its
interaction with the type III TGF-β receptor. PLoS One.
7:e327052012. View Article : Google Scholar
|
|
32
|
Massague J: TGFβ signalling in context.
Nat Rev Mol Cell Biol. 13:616–630. 2012. View Article : Google Scholar
|
|
33
|
Vincent T, Neve EP, Johnson JR, Kukalev A,
Rojo F, Albanell J, Pietras K, Virtanen I, Philipson L, Leopold PL,
et al: A SNAIL1SMAD3/4 transcriptional repressor complex promotes
TGF-beta mediated epithelial-mesenchymal transition. Nat Cell Biol.
11:943–950. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Hu WQ, Wang LW, Yuan JP, Yan SG, Li JD,
Zhao HL, Peng CW, Yang GF and Li Y: High expression of transform
growth factor beta 1 in gastric cancer confers worse outcome:
Results of a cohort study on 184 patients. Hepatogastroenterology.
61:245–250. 2014.PubMed/NCBI
|
|
35
|
Moon HJ, Finney J, Xu L, Moore D, Welch DR
and Mure M: MCF-7 cells expressing nuclear associated lysyl
oxidase-like 2 (LOXL2) exhibit an epithelial-to-mesenchymal
transition (EMT) phenotype and are highly invasive in vitro. J Biol
Chem. 288:30000–30008. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Osawa T, Ohga N, Akiyama K, Hida Y,
Kitayama K, Kawamoto T, Yamamoto K, Maishi N, Kondoh M, Onodera Y,
et al: Lysyl oxidase secreted by tumour endothelial cells promotes
angio-genesis and metastasis. Br J Cancer. 109:2237–2247. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Cox TR, Rumney RMH, Schoof EM, Perryman L,
Høye AM, Agrawal A, Bird D, Latif NA, Forrest H, Evans HR, et al:
The hypoxic cancer secretome induces pre-metastatic bone lesions
through lysyl oxidase. Nature. 522:106–110. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Hua YJ, Wang HY, Tang LQ, Chen QY, Shao JY
and Mai HQ: LOX expression in primary nasopharyngeal carcinoma:
Correlation with prognostic parameters and outcome. Oncotarget.
7:8200–8207. 2016. View Article : Google Scholar : PubMed/NCBI
|
