|
1
|
Makris EA, Gomoll AH, Malizos KN, Hu JC
and Athanasiou KA: Repair and tissue engineering techniques for
articular cartilage. Nat Rev Rheumatol. 11:21–34. 2015. View Article : Google Scholar :
|
|
2
|
Caron MM, Emans PJ, Coolsen MME, Voss L,
Surtel DAM, Cremers A, van Rhijn LW and Welting TJ:
Redifferentiation of dedifferentiated human articular chondrocytes:
Comparison of 2D and 3D cultures. Osteoarthr Cartilage.
20:1170–1178. 2012. View Article : Google Scholar
|
|
3
|
Duan L, Ma B, Liang Y, Chen J, Zhu W, Li M
and Wang D: Cytokine networking of chondrocyte dedifferentiation in
vitro and its implications for cell-based cartilage therapy. Am J
Transl Res. 7:194–208. 2015.PubMed/NCBI
|
|
4
|
Darling EM and Athanasiou KA: Rapid
phenotypic changes in passaged articular chondrocyte
subpopulations. J Orthop Res. 23:425–432. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Duval E, Leclercq S, Elissalde JM, Demoor
M, Galéra P and Boumédiene K: Hypoxia-inducible factor 1alpha
inhibits the fibroblast-like markers type I and type III collagen
during hypoxia-induced chondrocyte redifferentiation: Hypoxia not
only induces type II collagen and aggrecan, but it also inhibits
type I and type III collagen in the hypoxia-inducible factor
1alpha-dependent redifferentiation of chondrocytes. Arthritis
Rheum. 60:3038–3048. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Schipani E, Ryan HE, Didrickson S,
Kobayashi T, Knight M and Johnson RS: Hypoxia in cartilage:
HIF-1alpha is essential for chondrocyte growth arrest and survival.
Gene Dev. 15:2865–2876. 2001.PubMed/NCBI
|
|
7
|
Brucker PU, Izzo NJ and Chu CR: Tonic
activation of hypoxia-inducible factor 1alpha in avascular
articular cartilage and implications for metabolic homeostasis.
Arthritis Rheum. 52:3181–3191. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Schrobback K, Klein TJ, Crawford R, Upton
Z, Malda J and Leavesley DI: Effects of oxygen and culture system
on in vitro propagation and redifferentiation of osteoarthritic
human articular chondrocytes. Cell Tissue Res. 347:649–663. 2012.
View Article : Google Scholar
|
|
9
|
Mhanna R, Öztürk E, Schlink P and
Zenobi-Wong M: Probing the microenvironmental conditions for
induction of superficial zone protein expression. Osteoarthr
Cartilage. 21:1924–1932. 2013. View Article : Google Scholar
|
|
10
|
Mennan C, Garcia J, McCarthy H, Owen S,
Perry J, Wright K, Banerjee R, Richardson JB and Roberts S: Human
articular chondrocytes retain their phenotype in sustained hypoxia
while normoxia promotes their immunomodulatory potential.
Cartilage. Apr 1–2018.Epub ahead of print. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Robins JC, Akeno N, Mukherjee A, Dalal RR,
Aronow BJ, Koopman P and Clemens TL: Hypoxia induces
chondrocyte-specific gene expression in mesenchymal cells in
association with transcriptional activation of Sox9. Bone.
37:313–322. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Koay EJ and Athanasiou KA: Hypoxic
chondrogenic differentiation of human embryonic stem cells enhances
cartilage protein synthesis and biomechanical functionality.
Osteoarthr Cartilage. 16:1450–1456. 2008. View Article : Google Scholar
|
|
13
|
Kawato Y, Hirao M, Ebina K, Tamai N, Shi
K, Hashimoto J, Yoshikawa H and Myoui A: Nkx3.2-induced suppression
of Runx2 is a crucial mediator of hypoxia-dependent maintenance of
chondrocyte phenotypes. Biochem Biophys Res Commun. 416:205–210.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Maes C, Carmeliet G and Schipani E:
Hypoxia-driven pathways in bone development, regeneration and
disease. Nat Rev Rheumatol. 8:358–366. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Thoms BL, Dudek KA, Lafont JE and Murphy
CL: Hypoxia promotes the production and inhibits the destruction of
human articular cartilage. Arthritis Rheum. 65:1302–1312. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Markway BD, Cho H and Johnstone B: Hypoxia
promotes redifferentiation and suppresses markers of hypertrophy
and degeneration in both healthy and osteoarthritic chondrocytes.
Arthritis Res Ther. 15:R92. 2013. View
Article : Google Scholar : PubMed/NCBI
|
|
17
|
Coyle CH, Izzo NJ and Chu CR: Sustained
hypoxia enhances chondrocyte matrix synthesis. J Orthop Res.
27:793–799. 2009. View Article : Google Scholar
|
|
18
|
Pfander D, Cramer T, Schipani E and
Johnson RS: HIF-1alpha controls extracellular matrix synthesis by
epiphyseal chondrocytes. J Cell Sci. 116:1819–1826. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Villemure I and Stokes IA: Growth plate
mechanics and mechanobiology. A survey of present understanding. J
Biomech. 42:1793–1803. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Heallen T, Morikawa Y, Leach J, Tao G,
Willerson JT, Johnson RL and Martin JF: Hippo signaling impedes
adult heart regeneration. Development. 140:4683–4690. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Halder G and Johnson RL: Hippo signaling:
Growth control and beyond. Development. 138:9–22. 2011. View Article : Google Scholar :
|
|
22
|
Yang B, Sun H, Song F, Yu M, Wu Y and Wang
J: YAP1 negatively regulates chondrocyte differentiation partly by
activating the β-catenin signaling pathway. Int J Biochem Cell
Biol. 87:104–113. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Loboda A, Jozkowicz A and Dulak J: HIF-1
versus HIF-2-is one more important than the other. Vasc Pharmacol.
56:245–251. 2012. View Article : Google Scholar
|
|
24
|
Gilkes DM, Xiang L, Lee SJ, Chaturvedi P,
Hubbi ME, Wirtz D and Semenza GL: Hypoxia-inducible factors mediate
coordinated RhoA-ROCK1 expression and signaling in breast cancer
cells. Proc Natl Acad Sci USA. 111:E384–E393. 2014. View Article : Google Scholar
|
|
25
|
Qi C, Zhang J, Chen X, Wan J, Wang J,
Zhang P and Liu Y: Hypoxia stimulates neural stem cell
proliferation by increasing HIF-1α expression and activating
Wnt/β-catenin signaling. Cell Mol Biol (Noisy-le-grand). 63:12–19.
2017. View Article : Google Scholar :
|
|
26
|
Zhang C, Li Y, Cornelia R, Swisher S and
Kim H: Regulation of VEGF expression by HIF-1α in the femoral head
cartilage following ischemia osteonecrosis. Sci Rep. 2:6502012.
View Article : Google Scholar
|
|
27
|
Lefebvre V and Smits P: Transcriptional
control of chondrocyte fate and differentiation. Birth Defects Res
C Embryo Today. 75:200–212. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Saito T, Fukai A, Mabuchi A, Ikeda T, Yano
F, Ohba S, Nishida N, Akune T, Yoshimura N, Nakagawa T, et al:
Transcriptional regulation of endochondral ossification by
HIF-2alpha during skeletal growth and osteoarthritis development.
Nat Med. 16:678–686. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Amarilio R, Viukov SV, Sharir A,
Eshkar-Oren I, Johnson RS and Zelzer E: HIF1alpha regulation of
Sox9 is necessary to maintain differentiation of hypoxic
prechondrogenic cells during early skeletogenesis. Development.
134:3917–3928. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kosyna FK, Nagel M, Kluxen L, Kraushaar K
and Depping R: The importin α/β-specific inhibitor Ivermectin
affects HIF-dependent hypoxia response pathways. Biol Chem.
396:1357–1367. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Provot S, Zinyk D, Gunes Y, Kathri R, Le
Q, Kronenberg HM, Johnson RS, Longaker MT, Giaccia AJ and Schipani
E: Hif-1alpha regulates differentiation of limb bud mesenchyme and
joint development. J Cell Biol. 177:451–464. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Duval E, Baugé C, Andriamanalijaona R,
Bénateau H, Leclercq S, Dutoit S, Poulain L, Galéra P and
Boumédiene K: Molecular mechanism of hypoxia-induced chondrogenesis
and its application in in vivo cartilage tissue engineering.
Biomaterials. 33:6042–6051. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Morais-Faria K, Menegussi G, Marta G,
Fernandes PM, Dias RB, Ribeiro AC, Lopes MA, Cernea CR, Brandão TB
and Santos-Silva AR: Dosimetric distribution to the teeth of
patients with head and neck cancer who underwent radiotherapy. Oral
Surg Oral Med Oral Pathol Oral Radiol. 120:416–419. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Zhao B, Tumaneng K and Guan KL: The Hippo
pathway in organ size control, tissue regeneration and stem cell
self-renewal. Nat Cell Biol. 13:877–883. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yu FX, Zhao B and Guan KL: Hippo pathway
in organ size control, tissue homeostasis, and cancer. Cell.
163:811–828. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Studer L, Csete M, Lee SH, Kabbani N,
Walikonis J, Wold B and McKay R: Enhanced proliferation, survival,
and dopaminergic differentiation of CNS precursors in lowered
oxygen. J Neurosci. 20:7377–7383. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Ramos A and Camargo FD: The Hippo
signaling pathway and stem cell biology. Trends Cell Biol.
22:339–346. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhao B, Wei X, Li W, Udan RS, Yang Q, Kim
J, Xie J, Ikenoue T, Yu J, Li L, et al: Inactivation of YAP
oncoprotein by the Hippo pathway is involved in cell contact
inhibition and tissue growth control. Gene Dev. 21:2747–2761. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Liu H, Jiang D, Chi F and Zhao B: The
Hippo pathway regulates stem cell proliferation, self-renewal, and
differentiation. Protein Cell. 3:291–304. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Dupont S, Morsut L, Aragona M, Enzo E,
Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M,
Bicciato S, et al: Role of YAP/TAZ in mechanotransduction. Nature.
474:179–183. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Azzolin L, Zanconato F, Bresolin S,
Forcato M, Basso G, Bicciato S, Cordenonsi M and Piccolo S: Role of
TAZ as mediator of Wnt signaling. Cell. 151:1443–1456. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Byun MR, Jeong H, Bae SJ, Kim AR, Hwang ES
and Hong JH: TAZ is required for the osteogenic and anti-adipogenic
activities of kaempferol. Bone. 50:364–372. 2012. View Article : Google Scholar
|
|
43
|
Deng Y, Wu A, Li P, Li G, Qin L, Song H
and Mak KK: Yap1 Regulates multiple steps of chondrocyte
differentiation during skeletal development and bone repair. Cell
Rep. 14:2224–2237. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Ying J, Wang P, Zhang S, Xu T, Zhang L,
Dong R, Xu S, Tong P, Wu C and Jin H: Transforming growth
factor-beta1 promotes articular cartilage repair through canonical
Smad and Hippo pathways in bone mesenchymal stem cells. Life Sci.
192:84–90. 2018. View Article : Google Scholar
|
|
45
|
Chen Ma, Chen YB, Cheng L, Mu H, Li C, Gao
J, Zhou R, Cao C, Liu LJ, et al: Hypoxia regulates Hippo signalling
through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 17:95–103.
2015.
|
|
46
|
Chen H, Chen Q and Luo Q: Expression of
netrin-1 by hypoxia contributes to the invasion and migration of
prostate carcinoma cells by regulating YAP activity. Exp Cell Res.
349:302–309. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Yan L, Cai Q and Xu Y: Hypoxic conditions
differentially regulate TAZ and YAP in cancer cells. Arch Biochem
Biophys. 562:31–36. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Zhang C, Bian M, Chen X, Jin H, Zhao S,
Yang X, Shao J, Chen A, Guo Q, Zhang F and Zheng S: Oroxylin A
prevents angiogenesis of LSECs in liver fibrosis via inhibition of
YAP/HIF-1α signaling. J Cell Biochem. 119:2258–2268. 2018.
View Article : Google Scholar
|
