Journal Articles
Review
Evidence and perspective for the role of the NLRP3 inflammasome signaling pathway in ischemic stroke and its therapeutic potential (Review)
Chongyang Ma, Shuling Liu, Shuang Zhang, Tian Xu, Xue Yu, Yushan Gao, Changming Zhai, Changxiang Li, Chaofang Lei, Shuning Fan, Yuxi Chen, Huiling Tian, Qingguo Wang, Fafeng Cheng, Xueqian Wang
Pages: 2979-2990 Published online on: 02 October 2018
Review
TRAPPC9: Novel insights into its trafficking and signaling pathways in health and disease (Review)
Thomas Mbimba, Nazar J. Hussein, Ayesha Najeed, Fayez F. Safadi
Pages: 2991-2997 Published online on: 21 September 2018
Review
Maintenance of intracellular Ca2+ basal concentration in airway smooth muscle (Review)
Jorge Reyes‑García, Edgar Flores‑Soto, Abril Carbajal‑García, Bettina Sommer, Luis M. Montaño
Pages: 2998-3008 Published online on: 02 October 2018
Article
Suppressive effect of an analog of the antimicrobial peptide of LL‑37 on colon cancer cells via exosome‑encapsulated miRNAs
Miwa Hayashi, Kengo Kuroda, Kohei Ihara, Takahiro Iwaya, Emiko Isogai
Pages: 3009-3016 Published online on: 13 September 2018
Article
Silencing of NOD2 protects against diabetic cardiomyopathy in a murine diabetes model
Lin Shen, Li Li, Man Li, Weiling Wang, Wenbin Yin, Wei Liu, Yanyan Hu
Pages: 3017-3026 Published online on: 14 September 2018
Article
miR-214 regulates papillary thyroid carcinoma cell proliferation and metastasis by targeting PSMD10
Fangzhou Liu, Kexin Lou, Xiaotong Zhao, Jia Zhang, Wei Chen, Yichun Qian, Yanbin Zhao, Yan Zhu, Yuan Zhang
Pages: 3027-3036 Published online on: 27 September 2018
Article
Ghrelin protects the myocardium with hypoxia/reoxygenation treatment through upregulating the expression of growth hormone, growth hormone secretagogue receptor and insulin-like growth factor-1, and promoting the phosphorylation of protein kinase B
Yang Liu, Yanling Liu, Guolin Li, Zhengrong Chen, Guixiong Gu
Pages: 3037-3046 Published online on: 18 September 2018
Article
Anti-obesity and fatty liver-preventing activities of Lonicera caerulea in high-fat diet-fed mice
Joo Wan Kim, You‑Suk Lee, Du Jin Seol, Il Je Cho, Sae Kwang Ku, Jae‑Suk Choi, Hae‑Jeung Lee
Pages: 3047-3064 Published online on: 14 September 2018
Article
DPY30 is required for the enhanced proliferation, motility and epithelial-mesenchymal transition of epithelial ovarian cancer cells
Lili Zhang, Shuguang Zhang, Aihua Li, Anqi Zhang, Shiqian Zhang, Liang Chen
Pages: 3065-3072 Published online on: 11 September 2018
Article
Protective effect of luteolin on skin ischemia-reperfusion injury through an AKT-dependent mechanism
Gang Chen, Hugang Shen, Linlin Zang, Zhonglan Su, Jilong Huang, Yong Sun, Hongwei Wang
Pages: 3073-3082 Published online on: 02 October 2018
Article
BML-111 suppresses TGF-β1-induced lung fibroblast activation in vitro and decreases experimental pulmonary fibrosis in vivo
Yu‑Dong Ji, Zhen‑Long Luo, Chun‑Xiu Chen, Bo Li, Jie Gong, Ya‑Xin Wang, Lin Chen, Shang‑Long Yao, You Shang
Pages: 3083-3092 Published online on: 02 October 2018
Article
Astragalus polysaccharide combined with 10-hydroxycamptothecin inhibits metastasis in non-small cell lung carcinoma cell lines via the MAP4K3/mTOR signaling pathway
Yang Zhou, Tao Hong, Li Tong, Wei Liu, Xueting Yang, Jianghan Luo, Fuling Wang, Jian Li, Lijun Yan
Pages: 3093-3104 Published online on: 07 September 2018
Article
A 44-gene set constructed for predicting the prognosis of clear cell renal cell carcinoma Corrigendum in /10.3892/ijmm.2019.4138
Yonggang Wang, Yao Wang, Feng Liu
Pages: 3105-3114 Published online on: 26 September 2018
Article
miR-1307-3p suppresses the chondrogenic differentiation of human adipose-derived stem cells by targeting BMPR2
Zhen Yang, Rui Li, Jun Ao, Qing‑De Wa, Yi Zhang, Long Chen, Jing Wen, Biao Chen, Wei Pan, Bo Li, Xiao‑Bin Tian
Pages: 3115-3124 Published online on: 21 September 2018
Article
Silencing of Annexin A1 suppressed the apoptosis and inflammatory response of preeclampsia rat trophoblasts
Jing Feng, Xinling Wang, Hongyan Li, Li Wang, Zengjun Tang
Pages: 3125-3134 Published online on: 18 September 2018
Article
Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway
Xiaoqi Zhang, Hao Feng, Juan Du, Jing Sun, Dongfang Li, Tomoka Hasegawa, Norio Amizuka, Minqi Li
Pages: 3135-3148 Published online on: 17 September 2018
Article
(-)-Epigallocatechin gallate but not chlorogenic acid suppresses EGF-stimulated migration of osteoblasts via attenuation of p38 MAPK activity
Tetsu Kawabata, Takanobu Otsuka, Kazuhiko Fujita, Go Sakai, Rie Matsushima‑Nishiwaki, Osamu Kozawa, Haruhiko Tokuda
Pages: 3149-3156 Published online on: 18 September 2018
Article
Total C-21 steroidal glycosides, isolated from the root tuber of Cynanchum auriculatum Royle ex Wight, attenuate hydrogen peroxide-induced oxidative injury and inflammation in L02 cells
Zhenhui Wu, Yingyu Wang, Xian Meng, Xinjie Wang, Zhenlin Li, Shihui Qian, Yingjie Wei, Luan Shu, Yongfang Ding, Peijuan Wang, Yunru Peng
Pages: 3157-3170 Published online on: 25 September 2018
Article
MicroRNA-145 regulates the proliferation, migration and invasion of human primary colon adenocarcinoma cells by targeting MAPK1
Yong Yang, Xiao‑Jia Li, Peng Li, Xiu‑Tian Guo
Pages: 3171-3180 Published online on: 01 October 2018
Article
Hypoxia promotes maintenance of the chondrogenic phenotype in rat growth plate chondrocytes through the HIF-1α/YAP signaling pathway
Hao Li, Xiaojuan Li, Xingzhi Jing, Mi Li, Ye Ren, Jingyuan Chen, Caihong Yang, Hua Wu, Fengjing Guo
Pages: 3181-3192 Published online on: 09 October 2018
Article
THR1 mediates GCN4 and CDC4 to link morphogenesis with nutrient sensing and the stress response in Candida albicans
Yuan‑Ti Lee, Yi‑Ya Fang, Yu Wen Sun, Hsiao‑Chi Hsu, Shan‑Mei Weng, Tzu‑Ling Tseng, Ting‑Hui Lin, Jia‑Ching Shieh
Pages: 3193-3208 Published online on: 12 October 2018
Article
Tizanidine exerts anti-nociceptive effects in spared nerve injury model of neuropathic pain through inhibition of TLR4/NF-κB pathway
Wanmin Pei, Yi Zou, Wenting Wang, Lai Wei, Yuan Zhao, Li Li
Pages: 3209-3219 Published online on: 13 September 2018
Article
Fisetin inhibits pristine-induced systemic lupus erythematosus in a murine model through CXCLs regulation
Su‑Ping Xu, Yong‑Sheng Li
Pages: 3220-3230 Published online on: 01 October 2018
Article
Evaluation of the effect of various main elements on the PrPSc detection by real-time quaking-induced conversion assay
Kang Xiao, Qi Shi, Wei Zhou, Chen Gao, Cao Chen, Bao‑Yun Zhang, Jing Wang, Xiao‑Ping Dong
Pages: 3231-3237 Published online on: 07 September 2018
Article
Anti-microRNA-132 causes sevoflurane‑induced neuronal apoptosis via the PI3K/AKT/FOXO3a pathway
Ping Dong, Xiyan Zhang, Jian Zhao, Dongliang Li, Liang Li, Bo Yang
Pages: 3238-3246 Published online on: 25 September 2018
Article
Evodiamine alleviates severe pneumonia induced by methicillin-susceptible Staphylococcus aureus following cytomegalovirus reactivation through suppressing NF-κB and MAPKs
Xin Chen, Shujun Zhou, Hui Li
Pages: 3247-3255 Published online on: 11 October 2018
Article
Potential regulatory role of circular RNA in idiopathic pulmonary fibrosis
Rongrong Li, Youlei Wang, Xiaodong Song, Wenjing Sun, Jinjin Zhang, Yuxia Liu, Hongbo Li, Chao Meng, Jie Zhang, Qingyin Zheng, Changjun Lv
Pages: 3256-3268 Published online on: 24 September 2018
Article
Expression levels of hnRNP K and p21WAF1/CIP1 are associated with resistance to radiochemotherapy independent of p53 pathway activation in rectal adenocarcinoma
Wassiliki Daskalaki, Eva Wardelmann, Matthias Port, Katharina Stock, Julie Steinestel, Sebastian Huss, Jan Sperveslage, Konrad Steinestel, Stefan Eder
Pages: 3269-3277 Published online on: 25 September 2018
Article
O-GlcNAc-modified SNAP29 inhibits autophagy-mediated degradation via the disturbed SNAP29-STX17-VAMP8 complex and exacerbates myocardial injury in type I diabetic rats
Lin Huang, Ping Yuan, Peng Yu, Qiling Kong, Zixuan Xu, Xia Yan, Yang Shen, Juesheng Yang, Rong Wan, Kui Hong, Yanhua Tang, Jinzhu Hu
Pages: 3278-3290 Published online on: 07 September 2018
Article
Long non-coding RNA C5orf66-AS1 prevents oral squamous cell carcinoma through inhibiting cell growth and metastasis
Tianzhu Lu, Hongjing Liu, Ganhua You
Pages: 3291-3299 Published online on: 02 October 2018
Article
Trifluoperazine prevents FOXO1 nuclear excretion and reverses doxorubicin-resistance in the SHG44/DOX drug-resistant glioma cell line
Xiaozhong Chen, Xiaoquan Luo, Yuan Cheng
Pages: 3300-3308 Published online on: 18 September 2018
Article
MicroRNA-552 promotes hepatocellular carcinoma progression by downregulating WIF1
Chao Li, Zi Wang, Shuangjiang Chen, Jingyao Zhang, Kai Qu, Chang Liu
Pages: 3309-3317 Published online on: 17 September 2018
Article
Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions
Zuzana Danková, Dušan Braný, Dana Dvorská, Marcela Ňachajová, Roman Fiolka, Marián Grendár, Jozef Hatok, Peter Kubatka, Veronika Holubeková, Erika Halašová, Tibor Bielik, Pavol Žúbor
Pages: 3318-3328 Published online on: 12 September 2018
Article
Regulation of the MAPK signaling pathway by miR-421-5p in rats under light pollution
Qianwen Ma, Yong Tan, Xuan Chen, Shuping Chen, Yuying Sun, Beibei Zhou
Pages: 3329-3343 Published online on: 13 September 2018
Article
Sphingomyelin synthase 2 promotes H2O2-induced endothelial dysfunction by activating the Wnt/β-catenin signaling pathway
Panpan Zhang, Lingyue Hua, Huan Hou, Xingyue Du, Zhiqiang He, Menghan Liu, Xiaojuan Hu, Nianlong Yan
Pages: 3344-3354 Published online on: 19 September 2018
Article
Knockdown of miR-194-5p inhibits cell proliferation, migration and invasion in breast cancer by regulating the Wnt/β-catenin signaling pathway
Feibiao Yang, Zhangsheng Xiao, Songze Zhang
Pages: 3355-3363 Published online on: 25 September 2018
Article
In vitro analysis of microRNA-26a in chronic lymphocytic leukemia cells
Jing Li, Chang‑Kui Sun
Pages: 3364-3370 Published online on: 10 October 2018
Article
Age-associated decline in Nrf2 signaling and associated mtDNA damage may be involved in the degeneration of the auditory cortex: Implications for central presbycusis
Yongqin Li, Xueyan Zhao, Yujuan Hu, Haiying Sun, Zuhong He, Jie Yuan, Hua Cai, Yu Sun, Xiang Huang, Wen Kong, Weijia Kong
Pages: 3371-3385 Published online on: 01 October 2018
Article
Anti-metastatic effect of 131I-labeled Buthus martensii Karsch chlorotoxin in gliomas
Shan Wu, Ke Ma, Wen‑Li Qiao, Ling‑Zhou Zhao, Chang‑Cun Liu, Li‑Lei Guo, Yan Xing, Mei‑Lin Zhu, Jin‑Hua Zhao
Pages: 3386-3394 Published online on: 01 October 2018
Article
TGF-β1 secreted by M2 phenotype macrophages enhances the stemness and migration of glioma cells via the SMAD2/3 signalling pathway
Zhengzheng Liu, Weilu Kuang, Qin Zhou, Yingying Zhang
Pages: 3395-3403 Published online on: 09 October 2018
Article
Cytokine-induced alterations of BAMBI mediate the reciprocal regulation of human Th17/Treg cells in response to cigarette smoke extract
Hong‑Ju Liu, Gang Chen, Long Chen, Mei Zhou, Xian‑Zhi Xiong, Zhao‑Ji Meng, Sheng‑Wen Sun, Xiao‑Nan Tao
Pages: 3404-3414 Published online on: 09 October 2018
Article
Rosuvastatin reduces the pro-inflammatory effects of adriamycin on the expression of HMGB1 and RAGE in rats
Haiyan Zhang, Xiang Lu, Zhengxia Liu, Kang Du
Pages: 3415-3423 Published online on: 11 October 2018
Article
SOSTDC1 inhibits bone metastasis in non-small cell lung cancer and may serve as a clinical therapeutic target
Guanghui Chen, Haiyi Gong, Ting Wang, Jian Wang, Zhitao Han, Guangjian Bai, Shuai Han, Xinghai Yang, Wang Zhou, Tielong Liu, Jianru Xiao
Pages: 3424-3436 Published online on: 10 October 2018
Article
Calcium‑sensing receptors in human peripheral T lymphocytes and AMI: Cause and effect
Jingya Zeng, Ying Pan, Baohong Cui, Taiyu Zhai, Song Gao, Qianyu Zhao, Yihua Sun
Pages: 3437-3446 Published online on: 10 October 2018
Article
In vitro free radical scavenging capacity of dimethylglycine sodium salt and its protective ability against oleic acid hydroperoxide-induced oxidative damage in IPEC-J2 cells
Kaiwen Bai, Luyi Jiang, Ligen Zhang, Yongwei Zhao, Yi Lu, Jingya Zhu, Jie Cai, Lili Zhang, Tian Wang
Pages: 3447-3458 Published online on: 13 September 2018
Article
Hyperosmotic stress stimulates autophagy via the NFAT5/mTOR pathway in cardiomyocytes
Hong Zhu, Wei Cao, Peng Zhao, Jieyu Wang, Yuying Qian, Yun Li
Pages: 3459-3466 Published online on: 12 September 2018
Article
Effect of deubiquitinase USP8 on hypoxia/reoxygenation‑induced inflammation by deubiquitination of TAK1 in renal tubular epithelial cells
Yuwei Zhang, Yingquan Luo, Yina Wang, Hong Liu, Yu Yang, Qiong Wang
Pages: 3467-3476 Published online on: 17 September 2018
Article
LY3009120, a pan-Raf kinase inhibitor, inhibits adipogenesis of 3T3-L1 cells by controlling the expression and phosphorylation of C/EBP-α, PPAR-γ, STAT‑3, FAS, ACC, perilipin A, and AMPK
Su‑Min Yang, Yu‑Kyoung Park, Jee In Kim, Yun‑Han Lee, Tae‑Yun Lee, Byeong‑Churl Jang
Pages: 3477-3484 Published online on: 21 September 2018
Article
Lithocarpus polystachyus Rehd. leaves aqueous extract protects against hydrogen peroxide‑induced SH-SY5Y cells injury through activation of Sirt3 signaling pathway
Jianmei Gao, Yingshu Xu, Jianyong Zhang, Jingshan Shi, Qihai Gong
Pages: 3485-3494 Published online on: 05 October 2018
Article
Preparation and biological evaluation of a novel pH-sensitive poly (β-malic acid) conjugate for antitumor drug delivery Corrigendum in /10.3892/ijmm.2019.4308
Youbei Qiao, Bao Liu, Yifan Peng, Erlong Ji, Hong Wu
Pages: 3495-3502 Published online on: 25 September 2018
Article
SFMBT2 positively regulates SOX9 and chondrocyte proliferation
Safdar Hussain, Mengyao Sun, Yuanxu Guo, Nosheen Mushtaq, Yitong Zhao, Ying Yuan, Nazim Hussain, Ezra Osoro, Abubakar Suleiman, Muhammad Sadiq, Fujun Zhang, Yan Han, Jian Sun, Shemin Lu
Pages: 3503-3512 Published online on: 25 September 2018
Article
Melatonin attenuates the inflammatory response via inhibiting the C/EBP homologous protein-mediated pathway in taurocholate-induced acute pancreatitis
Qian Zhao, Hui Zhang, Junhua Huang, Huajun Yu, Jiajia Li, Qinfen Che, Yangjie Sun, Yin Jin, Jiansheng Wu
Pages: 3513-3521 Published online on: 09 October 2018
Article
Adjudin delays cellular senescence through Sirt3‑mediated attenuation of ROS production
Keyi Geng, Ningzhen Fu, Xiao Yang, Weiliang Xia
Pages: 3522-3529 Published online on: 08 October 2018
Article
LOXL2, a copper-dependent monoamine oxidase, activates lung fibroblasts through the TGF-β/Smad pathway
Xiaohong Wen, Yuan Liu, Yu Bai, Mingwei Li, Qiang Fu, Yi Zheng
Pages: 3530-3541 Published online on: 11 October 2018
Article
Expression and mutations of BRCA in breast cancer and ovarian cancer: Evidence from bioinformatics analyses
Zhu Wang, Jianwen Zhang, Ying Zhang, Qiong Deng, Hui Liang
Pages: 3542-3550 Published online on: 11 September 2018
Article
Identification of three aquaporin subgroups from Blomia tropicalis by transcriptomics
Ying Zhou, Ling Li, Jun Qian, Haoyuan Jia, Yubao Cui
Pages: 3551-3561 Published online on: 13 September 2018
Article
miR-183 inhibits autophagy and apoptosis in gastric cancer cells by targeting ultraviolet radiation resistance-associated gene
Yuan Yuan, Youwei Zhang, Liang Han, Sanyuan Sun, Yongqian Shu
Pages: 3562-3570 Published online on: 11 September 2018
Article
Schisandrin B protects human keratinocyte-derived HaCaT cells from tert-butyl hydroperoxide-induced oxidative damage through activating the Nrf2 signaling pathway
Ming Ding, Peng Shu, Shuang Gao, Fenglou Wang, Yitian Gao, Yu Chen, Wenjuan Deng, Gaiying He, Zhenlin Hu, Tianduo Li
Pages: 3571-3581 Published online on: 26 September 2018
Article
Inflammatory stimuli promote oxidative stress in pancreatic acinar cells via Toll-like receptor 4/nuclear factor-κB pathway
Longfei Pan, Lei Yu, Liming Wang, Juntao He, Jiangli Sun, Xiaobo Wang, Hai Wang, Zhenghai Bai, Hui Feng, Honghong Pei
Pages: 3582-3590 Published online on: 01 October 2018
Article
The role of focal adhesion kinase in transforming growth factor-β2 induced migration of human lens epithelial cells
Jie Liu, Dan Xu, Jingming Li, Ning Gao, Chongbing Liao, Ruihua Jing, Bogang Wu, Bo Ma, Yongping Shao, Cheng Pei
Pages: 3591-3601 Published online on: 02 October 2018
Article
eRF3b-37 inhibits the TGF-β1-induced activation of hepatic stellate cells by regulating cell proliferation, G0/G1 arrest, apoptosis and migration
Zhengrong Xu, Tao Li, Man Li, Lei Yang, Rudan Xiao, Li Liu, Xin Chi, Dianwu Liu
Pages: 3602-3612 Published online on: 26 September 2018
Article
Anemarrhena asphodeloides Bunge ameliorates osteoporosis by suppressing osteoclastogenesis
Jae Sung Lee, Mi Hye Kim, Haesu Lee, Woong Mο Yang
Pages: 3613-3621 Published online on: 01 October 2018
Article
Secretogranin III may be an indicator of paraquat-induced astrocyte activation and affects the recruitment of BDNF during this process
Xiaoni Zhan, Fengrui Li, Qiaohong Chu, Hao Pang
Pages: 3622-3630 Published online on: 01 October 2018
Article
Repetitive magnetic stimulation promotes the proliferation of neural progenitor cells via modulating the expression of miR-106b
Hua Liu, Gaohua Li, Chunlian Ma, Yanfang Chen, Jinju Wang, Yi Yang
Pages: 3631-3639 Published online on: 09 October 2018
Retraction