|
1
|
Bouchier-Hayes L and Martin SJ: CARD games
in apoptosis and immunity. EMBO Rep. 3:616–621. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Hofmann K, Bucher P and Tschopp J: The
CARD domain: A new apoptotic signalling motif. Trends Biochem Sci.
22:155–156. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Kao WP, Yang CY, Su TW, Wang YT, Lo YC and
Lin SC: The versatile roles of CARDs in regulating apoptosis,
inflammation, and NF-κB signaling. Apoptosis. 20:174–195. 2015.
View Article : Google Scholar
|
|
4
|
Bae JY and Park HH: Crystal structure of
NALP3 protein pyrin domain (PYD) and its implications in
inflammasome assembly. J Biol Chem. 286:39528–39536. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Park HH, Lo YC, Lin SC, Wang L, Yang JK
and Wu H: The death domain superfamily in intracellular signaling
of apoptosis and inflammation. Ann Rev Immunol. 25:561–586. 2007.
View Article : Google Scholar
|
|
6
|
Park HH: Structural analyses of death
domains and their interactions. Apoptosis. 16:209–220. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Damiano JS and Reed JC: CARD proteins as
therapeutic targets in cancer. Curr Drug Targets. 5:367–374. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Kwon D, Yoon JH, Shin SY, Jang TH, Kim HG,
So I, Jeon JH and Park HH: A comprehensive manually curated
protein-protein interaction database for the Death Domain
superfamily. Nucleic Acids Res. 40:D331–D336. 2012. View Article : Google Scholar
|
|
9
|
Duan H and Dixit VM: RAIDD is a new
'death' adaptor molecule. Nature. 385:86–89. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Rodriguez J and Lazebnik Y: Caspase-9 and
APAF-1 form an active holoenzyme. Genes Dev. 13:3179–3184. 1999.
View Article : Google Scholar
|
|
11
|
Ahmad M, Srinivasula SM, Wang L, Talanian
RV, Litwack G, Fernandes-Alnemri T and Alnemri ES: CRADD, a novel
human apoptotic adaptor molecule for caspase-2, and FasL/tumor
necrosis factor receptor-interacting protein RIP. Cancer Res.
57:615–619. 1997.PubMed/NCBI
|
|
12
|
Denault JB and Salvesen GS: Caspases: Keys
in the ignition of cell death. Chem Rev. 102:4489–4500. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Donepudi M and Grutter MG: Structure and
zymogen activation of caspases. Biophys Chem. 101–102:145–153.
2002. View Article : Google Scholar
|
|
14
|
Ludwig-Galezowska AH, Flanagan L and Rehm
M: Apoptosis repressor with caspase recruitment domain, a
multifunctional modulator of cell death. J Cell Mol Med.
15:1044–1053. 2011. View Article : Google Scholar
|
|
15
|
Salvesen GS: Caspases and apoptosis.
Essays Biochem. 38:9–19. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Salvesen GS and Dixit VM: Caspases:
Intracellular signaling by proteolysis. Cell. 91:443–446. 1997.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Adams JM and Cory S: Apoptosomes: Engines
for caspase activation. Curr Opin Cell Biol. 14:715–720. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Pop C, Timmer J, Sperandio S and Salvesen
GS: The apoptosome activates caspase-9 by dimerization. Mol Cell.
22:269–275. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Acehan D, Jiang X, Morgan DG, Heuser JE,
Wang X and Akey CW: Three-dimensional structure of the apoptosome:
Implications for assembly, procaspase-9 binding, and activation.
Mol Cell. 9:423–432. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yu X, Acehan D, Menetret JF, Booth CR,
Ludtke SJ, Riedl SJ, Shi Y, Wang X and Akey CW: A structure of the
human apoptosome at 12.8 A resolution provides insights into this
cell death platform. Structure. 13:1725–1735. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Park HH: Structural features of
caspase-activating complexes. Int J Mol Sci. 13:4807–4818. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Manzl C, Krumschnabel G, Bock F, Sohm B,
Labi V, Baumgartner F, Logette E, Tschopp J and Villunger A:
Caspase-2 activation in the absence of PIDDosome formation. J Cell
Biol. 185:291–303. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Tinel A and Tschopp J: The PIDDosome, a
protein complex implicated in activation of caspase-2 in response
to genotoxic stress. Science. 304:843–846. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Chou JJ, Matsuo H, Duan H and Wagner G:
Solution structure of the RAIDD CARD and model for CARD/CARD
interaction in caspase-2 and caspase-9 recruitment. Cell.
94:171–180. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Gaide O, Martinon F, Micheau O, Bonnet D,
Thome M and Tschopp J: Carma1, a CARD-containing binding partner of
Bcl10, induces Bcl10 phosphorylation and NF-kappaB activation. FEBS
Lett. 496:121–127. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Bertin J, Wang L, Guo Y, Jacobson MD,
Poyet JL, Srinivasula SM, Merriam S, DiStefano PS and Alnemri ES:
CARD11 and CARD14 are novel caspase recruitment domain
(CARD)/membrane-associated guanylate kinase (MAGUK) family members
that interact with BCL10 and activate NF-kappa B. J Biol Chem.
276:11877–11882. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Qiao Q, Yang C, Zheng C, Fontan L, David
L, Yu X, Bracken C, Rosen M, Melnick A, Egelman EH and Wu H:
Structural architecture of the CARMA1/Bcl10/MALT1 signalosome:
Nucleation-induced filamentous assembly. Mol Cell. 51:766–779.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Hara H, Ishihara C, Takeuchi A, Imanishi
T, Xue L, Morris SW, Inui M, Takai T, Shibuya A, Saijo S, et al:
The adaptor protein CARD9 is essential for the activation of
myeloid cells through ITAM-associated and Toll-like receptors. Nat
Immunol. 8:619–629. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Hsu YM, Zhang Y, You Y, Wang D, Li H,
Duramad O, Qin XF, Dong C and Lin X: The adaptor protein CARD9 is
required for innate immune responses to intracellular pathogens.
Nat Immunol. 8:198–205. 2007. View
Article : Google Scholar
|
|
30
|
Hara H and Saito T: CARD9 versus CARMA1 in
innate and adaptive immunity. Trends Immunol. 30:234–242. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Uren AG, O'Rourke K, Aravind LA, Pisabarro
MT, Seshagiri S, Koonin EV and Dixit VM: Identification of
paracaspases and metacaspases: Two ancient families of caspase-like
proteins, one of which plays a key role in MALT lymphoma. Mol Cell.
6:961–967. 2000.PubMed/NCBI
|
|
32
|
Lucas PC, Yonezumi M, Inohara N,
McAllister-Lucas LM, Abazeed ME, Chen FF, Yamaoka S, Seto M and
Nunez G: Bcl10 and MALT1, independent targets of chromosomal
translocation in malt lymphoma, cooperate in a novel NF-kappa B
signaling pathway. J Biol Chem. 276:19012–19019. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Thome M: CARMA1, BCL-10 and MALT1 in
lymphocyte development and activation. Nat Rev Immunol. 4:348–359.
2004. View
Article : Google Scholar : PubMed/NCBI
|
|
34
|
Le HT and Harton JA: Pyrin- and CARD-only
proteins as regulators of NLR functions. Front Immunol. 4:2752013.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Martinon F, Burns K and Tschopp J: The
inflammasome: A molecular platform triggering activation of
inflammatory caspases and processing of proIL-beta. Mol Cell.
10:417–426. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Stehlik C and Dorfleutner A: COPs and
POPs: Modulators of inflammasome activity. J Immunol.
179:7993–7998. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Franchi L, Eigenbrod T, Munoz-Planillo R
and Nunez G: The inflammasome: A caspase-1-activation platform that
regulates immune responses and disease pathogenesis. Nat Immunol.
10:241–247. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Lee SH, Stehlik C and Reed JC: Cop, a
caspase recruitment domain-containing protein and inhibitor of
caspase-1 activation processing. J Biol Chem. 276:34495–34500.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Humke EW, Shriver SK, Starovasnik MA,
Fairbrother WJ and Dixit VM: ICEBERG: A novel inhibitor of
interleukin-1beta generation. Cell. 103:99–111. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Abmayr S, Crawford RW and Chamberlain JS:
Characterization of ARC, apoptosis repressor interacting with CARD,
in normal and dystrophin-deficient skeletal muscle. Hum Mol Genet.
13:213–221. 2004. View Article : Google Scholar
|
|
41
|
Koseki T, Inohara N, Chen S and Nunez G:
ARC, an inhibitor of apoptosis expressed in skeletal muscle and
heart that interacts selectively with caspases. Proc Natl Acad Sci
USA. 95:5156–5160. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Ha HJ and Park HH: Molecular basis for the
effect of the L31F mutation on CARD function in ARC. FEBS Lett.
591:2919–2928. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Nam YJ, Mani K, Ashton AW, Peng CF,
Krishnamurthy B, Hayakawa Y, Lee P, Korsmeyer SJ and Kitsis RN:
Inhibition of both the extrinsic and intrinsic death pathways
through nonho-motypic death-fold interactions. Mol Cell.
15:901–912. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Park HH: Molecular basis of dimerization
of initiator caspase was revealed by crystal structure of caspase-8
pro-domain. Cell Death Differ. 11–Sep;2018. View Article : Google Scholar
|
|
45
|
Foo RS, Nam YJ, Ostreicher MJ, Metzl MD,
Whelan RS, Peng CF, Ashton AW, Fu W, Mani K, Chin SF, et al:
Regulation of p53 tetramerization and nuclear export by ARC. Proc
Natl Acad Sci USA. 104:20826–20831. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
An J, Mehrhof F, Harms C, Lattig-Tunnemann
G, Lee SL, Endres M, Li M, Sellge G, Mandic AD, Trautwein C and
Donath S: ARC is a novel therapeutic approach against
acetaminophen-induced hepatocellular necrosis. J Hepatol.
58:297–305. 2013. View Article : Google Scholar
|
|
47
|
Mercier I, Vuolo M, Jasmin JF, Medina CM,
Williams M, Mariadason JM, Qian H, Xue X, Pestell RG, Lisanti MP
and Kitsis RN: ARC (apoptosis repressor with caspase recruitment
domain) is a novel marker of human colon cancer. Cell Cycle.
7:1640–1647. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Mercier I, Vuolo M, Madan R, Xue X,
Levalley AJ, Ashton AW, Jasmin JF, Czaja MT, Lin EY, Armstrong RC,
et al: ARC, an apoptosis suppressor limited to terminally
differentiated cells, is induced in human breast cancer and confers
chemo- and radiation-resistance. Cell Death Differ. 12:682–686.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Xu H, He X, Zheng H, Huang LJ, Hou F, Yu
Z, de la Cruz MJ, Borkowski B, Zhang X, Chen ZJ and Jiang QX:
Structural basis for the prion-like MAVS filaments in antiviral
innate immunity. Elife. 3:e014892014. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
de Alba E: Structure and interdomain
dynamics of apoptosis-associated speck-like protein containing a
CARD (ASC). J Biol Chem. 284:32932–32941. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Lopez J, John SW, Tenev T, Rautureau GJ,
Hinds MG, Francalanci F, Wilson R, Broemer M, Santoro MM, Day CL
and Meier P: CARD-mediated autoinhibition of cIAP1's E3 ligase
activity suppresses cell proliferation and migration. Mol Cell.
42:569–583. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Shiozaki EN, Chai J and Shi Y:
Oligomerization and activation of caspase-9, induced by apaf-1
CARD. Proc Natl Acad Sci USA. 99:4197–4202. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Zhou P, Chou J, Olea RS, Yuan J and Wagner
G: Solution structure of Apaf-1 CARD and its interaction with
caspase-9 CARD: A structural basis for specific adaptor/caspase
interaction. Proc Natl Acad Sci USA. 96:11265–11270. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Chen KE, Richards AA, Caradoc-Davies TT,
Vajjhala PR, Robin G, Lua LH, Hill JM, Schroder K, Sweet MJ, Kellie
S, et al: The structure of the caspase recruitment domain of
BinCARD reveals that all three cysteines can be oxidized. Acta
Crystallogr D Biol Crystallogr. 69:774–784. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Jin T, Huang M, Smith P, Jiang J and Xiao
TS: The structure of the CARD8 caspase-recruitment domain suggests
its association with the FIIND domain and procaspases through
adjacent surfaces. Acta Crystallogr Sect F Struct Biol Cryst
Commun. 69:482–487. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Potter JA, Randall RE and Taylor GL:
Crystal structure of human IPS-1/MAVS/VISA/Cardif caspase
activation recruitment domain. BMC Struct Biol. 8:112008.
View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Jin T, Curry J, Smith P, Jiang J and Xiao
TS: Structure of the NLRP1 caspase recruitment domain suggests
potential mechanisms for its association with procaspase-1.
Proteins. 81:1266–1270. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Manon F, Favier A, Nunez G, Simorre JP and
Cusack S: Solution structure of NOD1 CARD and mutational analysis
of its interaction with the CARD of downstream kinase RICK. J Mol
Biol. 365:160–174. 2007. View Article : Google Scholar
|
|
59
|
Ferrage F, Dutta K, Nistal-Villan E, Patel
JR, Sanchez-Aparicio MT, De Ioannes P, Buku A, Aseguinolaza GG,
Garcia-Sastre A and Aggarwal AK: Structure and dynamics of the
second CARD of human RIG-I provide mechanistic insights into
regulation of RIG-I activation. Structure. 20:2048–2061. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Jang TH, Park JH and Park HH: Novel
disulfide bond-mediated dimerization of the CARD domain was
revealed by the crystal structure of CARMA1 CARD. PLoS One.
8:e797782013. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Jang TH, Kim SH, Jeong JH, Kim S, Kim YG
and Park HH: Crystal structure of caspase recruiting domain (CARD)
of apoptosis repressor with CARD (ARC) and its implication in
inhibition of apoptosis. Sci Rep. 5:98472015. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Holm L and Sander C: Dali: A network tool
for protein structure comparison. Trends Biochem Sci. 20:478–480.
1995. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Qin H, Srinivasula SM, Wu G,
Fernandes-Alnemri T, Alnemri ES and Shi Y: Structural basis of
procaspase-9 recruitment by the apoptotic protease-activating
factor 1. Nature. 399:549–557. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
64
|
Park HH, Logette E, Rauser S, Cuenin S,
Walz T, Tschopp J and Wu H: Death domain assembly mechanism
revealed by crystal structure of the oligomeric PIDDosome core
complex. Cell. 128:533–546. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Coussens NP, Mowers JC, McDonald C, Nunez
G and Ramaswamy S: Crystal structure of the Nod1 caspase activation
and recruitment domain. Biochem Biophys Res Commun. 353:1–5. 2007.
View Article : Google Scholar
|
|
66
|
Cheng TC, Hong C, Akey IV, Yuan S and Akey
CW: A near aomic structure of the active human apoptosome. Elife.
4:e177552016. View Article : Google Scholar
|
|
67
|
Peisley A, Wu B, Xu H, Chen ZJ and Hur S:
Structural basis for ubiquitin-mediated antiviral signal activation
by RIG-I. Nature. 509:110–114. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Siegel RM, Martin DA, Zheng L, Ng SY,
Bertin J, Cohen J and Lenardo MJ: Death-effector filaments: Novel
cytoplasmic structures that recruit caspases and trigger apoptosis.
J Cell Biol. 141:1243–1253. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Li Y, Fu TM, Lu A, Witt K, Ruan J, Shen C
and Wu H: Cryo-EM structures of ASC and NLRC4 CARD filaments reveal
a unified mechanism of nucleation and activation of caspase-1. Proc
Natl Acad Sci USA. 115:10845–10852. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Lu A, Li Y, Schmidt FI, Yin Q, Chen S, Fu
TM, Tong AB, Ploegh HL, Mao Y and Wu H: Molecular basis of
caspase-1 polymerization and its inhibition by a new capping
mechanism. Nat Struct Mol Biol. 23:416–425. 2016. View Article : Google Scholar : PubMed/NCBI
|
