Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
Journal Cover
December-2019 Volume 44 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
December-2019 Volume 44 Issue 6

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis

  • Authors:
    • Furong Zhang
    • Can Tan
    • Yu Xu
    • Guoling Yang
  • View Affiliations / Copyright

    Affiliations: Department of Dermatology, The First Affiliated Hospital of Dalian Medical University, Chengdu, Sichuan 11736, P.R. China, Department of Dermatology, Hospital of Anjing Town, Chengdu, Sichuan 11736, P.R. China
    Copyright: © Zhang et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 2047-2056
    |
    Published online on: September 27, 2019
       https://doi.org/10.3892/ijmm.2019.4355
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

Microsporum canis (M. canis) is a common pathogen that causes tinea capitis and is present worldwide. The incidence of M. canis infection, particularly tinea capitis, has been increasing in China. In our previous studies, family of serine hydrolases 1 (FSH1) was identified as a potential virulence factor in tinea capitis infection caused by M. canis. To determine the function of this gene in M. canis, FSH1 was knocked down using double‑stranded RNA interference mediated by Agrobacterium tumefaciens. Reverse transcription‑quantitative PCR analysis was used to confirm gene knockdown. Loss of FSH1 expression by RNAi resulted in a minor phenotype alteration, but M. canis pathogenicity in guinea pig cutaneous infection was decreased compared with the wild‑type strain. To the best of our knowledge, the present study is the first to demonstrate that FSH1 is associated with macroconidia septa formation and is an important contributor to M. canis virulence. These findings may advance the understanding of the function of the FSH1 gene and provide a foundation for future studies on macroconidia septa formation and pathogenicity of M. canis.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

Figure 7

View References

1 

Mao L, Zhang L, Li H, Chen W, Wang H, Wu S, Guo C, Lu A, Yang G, An L, et al: Pathogenic fungus Microsporum canis activates the NLRP3 inflammasome. Infect Immun. 82:882–892. 2014. View Article : Google Scholar : PubMed/NCBI

2 

Yu J, Wan Z, Chen W, Wang W and Li R: Molecular typing study of the Microsporum canis strains isolated from an outbreak of tinea capitis in a school. Mycopathologia. 157:37–41. 2004. View Article : Google Scholar : PubMed/NCBI

3 

Vermout S, Baldo A, Tabart J, Losson B and Mignon B: Secreted dipeptidyl peptidases as potential virulence factors for Microsporum canis. FEMS Immunol Med Microbiol. 54:299–308. 2008. View Article : Google Scholar : PubMed/NCBI

4 

Brosh-Nissimov T, Ben-Ami R, Astman N, Malin A, Baruch Y and Galor I: An outbreak of Microsporum canis infection at a military base associated with stray cat exposure and person-to-person transmission. Mycoses. 61:472–476. 2018. View Article : Google Scholar : PubMed/NCBI

5 

Hermoso de Mendoza M, Hermoso de Mendoza J, Alonso JM, Rey JM, Sanchez S, Martin R, Bermejo F, Cortes M, Benitez JM, Garcia WL and Garcia-Sanchez A: A zoonotic ringworm outbreak caused by a dysgonic strain of Microsporum canis from stray cats. Rev Iberoam Micol. 27:62–65. 2010. View Article : Google Scholar : PubMed/NCBI

6 

Binder B, Lackner HK, Poessl BD, Propst E, Weger W, Smolle J and Ginter Hanselmayer G: Prevalence of tinea capitis in southeastern Austria between 1985 and 2008: Up-to-date picture of the current situation. Mycoses. 54:243–247. 2011. View Article : Google Scholar

7 

Del Boz J, Crespo V, Rivas-Ruiz F and de Troya M: A 30-year survey of paediatric tinea capitis in southern Spain. J Eur Acad Dermatol Venereol. 25:170–174. 2011. View Article : Google Scholar

8 

Costa M, Passos XS, Hasimoto e Souza LK, Miranda AT, Lemos Jde A, Oliveira JG Jr and Silva Mdo R: Epidemiology and etiology of dermatophytosis in Goiânia, GO, Brazil. Rev Soc Bras Med Trop. 35:19–22. 2002.In Portuguese. View Article : Google Scholar : PubMed/NCBI

9 

Doss RW, El-Rifaie AA, Radi N and El-Sherif AY: Antimicrobial susceptibility of tinea capitis in children from Egypt. Indian J Dermatol. 63:155–159. 2018.PubMed/NCBI

10 

Zhu M, Li L, Wang J, Zhang C, Kang K and Zhang Q: Tinea capitis in southeastern China: A 16-year survey. Mycopathologia. 169:235–239. 2010. View Article : Google Scholar

11 

Li C and Liu W: Epidemiology of tinea capitis among children in China in recent years: A retrospective analysis. Chin J Mycol. 6:77–82. 2011.

12 

Yin B, Xiao Y, Ran Y, Kang D, Dai Y and Lama J: Microsporum canis infection in three familial cases with tinea capitis and tinea corporis. Mycopathologia. 176:259–265. 2013. View Article : Google Scholar : PubMed/NCBI

13 

Berg JC, Hamacher KL and Roberts GD: Pseudomycetoma caused by Microsporum canis in an immunosuppressed patient: A case report and review of the literature. J Cutan Pathol. 34:431–434. 2007. View Article : Google Scholar : PubMed/NCBI

14 

Anemüller W, Baumgartner S and Brasch J: Atypical Microsporum canis variant in an immunosuppressed child. J Dtsch Dermatol Ges. 6:473–475. 2008.In English and German. View Article : Google Scholar

15 

Brillowska-Dabrowska A, Michalek E, Saunte DM, Nielsen SS and Arendrup MC: PCR test for Microsporum canis identification. Med Mycol. 51:576–579. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Sharma R, de Hoog S, Presber W and Gräser Y: A virulent genotype of Microsporum canis is responsible for the majority of human infections. J Med Microbiol. 56:1377–1385. 2007. View Article : Google Scholar : PubMed/NCBI

17 

Ayanbimpe GM, Taghir H, Diya A and Wapwera S: Tinea capitis among primary school children in some parts of central nigeria. Mycoses. 51:336–340. 2008. View Article : Google Scholar : PubMed/NCBI

18 

Patel GA and Schwartz RA: Tinea capitis: Still an unsolved problem? Mycoses. 54:183–188. 2011. View Article : Google Scholar

19 

Baldo A, Mathy A, Tabart J, Camponova P, Vermout S, Massart L, Maréchal F, Galleni M and Mignon B: Secreted subtilisin Sub3 from Microsporum canis is required for adherence to but not for invasion of the epidermis. Br J Dermatol. 162:990–997. 2010. View Article : Google Scholar

20 

Băguţ ET, Baldo A, Mathy A, Cambier L, Antoine N, Cozma V and Mignon B: Subtilisin Sub3 is involved in adherence of Microsporum canis to human and animal epidermis. Vet Microbiol. 160:413–419. 2012. View Article : Google Scholar

21 

Baldo A, Chevigné A, Dumez ME, Mathy A, Power P, Tabart J, Cambier L, Galleni M and Mignon B: Inhibition of the kerati-nolytic subtilisin protease Sub3 from Microsporum canis by its propeptide (proSub3) and evaluation of the capacity of proSub3 to inhibit fungal adherence to feline epidermis. Vet Microbiol. 159:479–484. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Shi Y, Niu Q, Yu X, Jia X, Wang J, Lin D and Jin Y: Assessment of the function of SUB6 in the pathogenic dermatophyte. Trichophyton mentagrophytes Med Mycol. 54:59–71. 2016.

23 

Grumbt M, Monod M, Yamada T, Hertweck C, Kunert J and Staib P: Keratin degradation by dermatophytes relies on cysteine dioxygenase and a sulfite efflux pump. J Invest Dermatol. 133:1550–1555. 2013. View Article : Google Scholar : PubMed/NCBI

24 

Mathy A, Baldo A, Schoofs L, Cambier L, Defaweux V, Tabart J, Maréchal F, Symoens F and Mignon B: Fungalysin and dipeptidyl-peptidase gene transcription in Microsporum canis strains isolated from symptomatic and asymptomatic cats. Vet Microbiol. 146:179–182. 2010. View Article : Google Scholar : PubMed/NCBI

25 

Nakayashiki H: RNA silencing in fungi: Mechanisms and applications. FEBS Lett. 579:5950–5957. 2005. View Article : Google Scholar : PubMed/NCBI

26 

Zhang FR, Zhang Y, Zhang ZY, Yang GL, Jing LJ and Bai YG: Analysis of the differentially expressed genes in Microsporum canis in inducing smooth skin and scalp tissue conditions. Clin Exp Dermatol. 36:896–902. 2011. View Article : Google Scholar : PubMed/NCBI

27 

Gräser Y, EI Fari M, Vilgalys R, Kuijpers AF, De Hoog GS, Presber W and Tietz H: Phylogeny and taxonomy of the family arthrodermataceae (dermatophytes) using sequence analysis of the ribosomal ITS region. Med Mycol. 37:105–114. 1999. View Article : Google Scholar : PubMed/NCBI

28 

Jackson CJ, Barton RC and Evans EG: Species identification and strain differentiation of dermatophyte fungi by analysis of ribosomal-DNA intergenic spacer regions. J Clin Microbiol. 37:931–936. 1999.PubMed/NCBI

29 

Zhang Z, Hou B, Wu YZ, Wang Y, Liu X and Han S: Two component histidine kinase DRK1 is required for pathogenesis in sporothrix schenckii. Mol Med Rep. 17:721–728. 2018.

30 

Zhang P, Xu B, Wang Y, Li Y, Qian Z, Tang S, Huan S and Ren S: Agrobacterium tumefaciens-mediated transformation as a tool for insertional mutagenesis in the fungus penicillium marneffei. Mycol Res. 112:943–949. 2008. View Article : Google Scholar : PubMed/NCBI

31 

Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001. View Article : Google Scholar

32 

Basma AA, Zuraini Z and Sasidharan SA: Transmission electron microscopy study of the diversity of Candida albicans cells induced by Euphorbia hirta L. Leaf extract in vitro Asian Pac J Trop Biomed. 1:20–22. 2011. View Article : Google Scholar

33 

Wang F, Tao J, Qian Z, You S, Dong H, Shen H, Chen X, Tang S and Ren S: A histidine kinase PmHHK1 regulates polar growth, sporulation and cell wall composition in the dimorphic fungus Penicillium marneffei. Mycol Res. 113:915–923. 2009. View Article : Google Scholar : PubMed/NCBI

34 

Jin XJ, Wang AP, Qiao JJ, Liu W, Wan J, Wang XH, Wu LS and Li RY: Establishment of an animal model of dermatophytosis and evaluation of the antifungal efficacy on dermatophytosis with this model. Chin J Dermatol. 42:125–128. 2009.In Chinese.

35 

Silverman J and Muir WW III: A review of laboratory animal anesthesia with chloral hydrate and chloralose. Lab Anim Sci. 43:210–216. 1993.PubMed/NCBI

36 

Olszewski J: Guinea pig as often object to otoneurological experimental examinations. Otolaryngol Pol. 61:838–841. 2007.In Polish. View Article : Google Scholar

37 

Mao N, Gao Q, Hu H, Zhu T and Hao L: BPA disrupts the cardio-protection by 17β-oestradiol against ischemia/reperfusion injury in isolated guinea pig hearts. Steroids. 146:50–56. 2019. View Article : Google Scholar : PubMed/NCBI

38 

Zhou Y, Song J, Wang YP, Zhang AM, Tan CY, Liu YH, Zhang ZP, Wang Y, Ma KT, Li L and Si JQ: Age-associated variation in the expression and function of TMEM16A calcium-activated chloride channels in the cochlear stria vascularis of guinea pigs. Mol Med Rep. 20:1593–1604. 2019.PubMed/NCBI

39 

Vermout S, Tabart J, Baldo A, Monod M, Losson B and Mignon B: RNA silencing in the dermatophyte Microsporum canis. FEMS Microbiol Lett. 275:38–45. 2007. View Article : Google Scholar : PubMed/NCBI

40 

Quevillon-Cheruel S, Leulliot N, Graille M, Hervouet N, Coste F, Bénédetti H, Zelwer C, Janin J and Van Tilbeurgh H: Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family. Protein Sci. 14:1350–1356. 2005. View Article : Google Scholar : PubMed/NCBI

41 

Baxter SM, Rosenblum JS, Knutson S, Nelson MR, Montimurro JS, Di Gennaro JA, Speir JA, Burbaum JJ and Fetrow JS: Synergistic computational and experimental proteomics approaches for more accurate detection of active serine hydrolases in yeast. Mol Cell Proteomics. 3:209–225. 2004. View Article : Google Scholar

42 

Gang L, Wei C, Yuqing T, Huarong T, Chater KF and Buttner MJ: A novel gene: sawD related to the differentiation of streptomyces ansochromogenes. Chin J Biotechnol. 15:195–202. 1999.

43 

Greenberg JH, King RD, Krebs S and Field R: A quantitative dermatophyte infection model in the guinea pig-a parallel to the quantitated human infection model. J Invest Dermatol. 67:704–708. 1976. View Article : Google Scholar : PubMed/NCBI

44 

Zhang X, Wang Y, Chi W, Shi Y, Chen S, Lin D and Jin Y: Metalloprotease genes of Trichophyton mentagrophytes are important for pathogenicity. Med Mycol. 52:36–45. 2014.

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Zhang F, Tan C, Xu Y and Yang G: FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis. Int J Mol Med 44: 2047-2056, 2019.
APA
Zhang, F., Tan, C., Xu, Y., & Yang, G. (2019). FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis. International Journal of Molecular Medicine, 44, 2047-2056. https://doi.org/10.3892/ijmm.2019.4355
MLA
Zhang, F., Tan, C., Xu, Y., Yang, G."FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis". International Journal of Molecular Medicine 44.6 (2019): 2047-2056.
Chicago
Zhang, F., Tan, C., Xu, Y., Yang, G."FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis". International Journal of Molecular Medicine 44, no. 6 (2019): 2047-2056. https://doi.org/10.3892/ijmm.2019.4355
Copy and paste a formatted citation
x
Spandidos Publications style
Zhang F, Tan C, Xu Y and Yang G: FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis. Int J Mol Med 44: 2047-2056, 2019.
APA
Zhang, F., Tan, C., Xu, Y., & Yang, G. (2019). FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis. International Journal of Molecular Medicine, 44, 2047-2056. https://doi.org/10.3892/ijmm.2019.4355
MLA
Zhang, F., Tan, C., Xu, Y., Yang, G."FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis". International Journal of Molecular Medicine 44.6 (2019): 2047-2056.
Chicago
Zhang, F., Tan, C., Xu, Y., Yang, G."FSH1 regulates the phenotype and pathogenicity of the pathogenic dermatophyte Microsporum canis". International Journal of Molecular Medicine 44, no. 6 (2019): 2047-2056. https://doi.org/10.3892/ijmm.2019.4355
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team