Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Molecular Medicine
Join Editorial Board Propose a Special Issue
Print ISSN: 1107-3756 Online ISSN: 1791-244X
Journal Cover
November-2020 Volume 46 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
November-2020 Volume 46 Issue 5

Full Size Image

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article Open Access

Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population

  • Authors:
    • Martha‑Spyridoula Katsarou
    • Polytimi Sidiropoulou
    • Dimitra Ieronymaki
    • Styliani Mastraftsi
    • Maria Sifaki
    • Kyriakos Xenos
    • Alexander Nosyrev
    • Leda Kovatsi
    • Demetrios A. Spandidos
    • Maria Lagiou
    • Christos Dagklis
    • Stamatis Gregoriou
    • Anna Tagka
    • Dimitris Rigopoulos
    • Nikolaos Drakoulis
    • Electra Nicolaidou
  • View Affiliations / Copyright

    Affiliations: Research Group of Clinical Pharmacology and Pharmacogenomics, Faculty of Pharmacy, School of Health Sciences, National and Kapodistrian University of Athens, 15784 Athens, Greece, 1st Department of Dermatology‑Venereology, Faculty of Medicine, National and Kapodistrian University of Athens, ‘A. Sygros’ Hospital for Skin and Venereal Diseases, 16121 Athens, Greece, Department of Dermatology‑Venereology, ‘A. Sygros’ Hospital for Skin and Venereal Diseases, 16121 Athens, Greece, Institute for Translational Medicine and Biotechnology, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119146 Moscow, Russia, Laboratory of Forensic Medicine and Toxicology, School of Medicine, Aristotle University of Thessaloniki, 54640 Thessaloniki, Greece, Laboratory of Clinical Virology, Medical School, University of Crete, 71003 Heraklion, Greece, Department of Statistics and Insurance Science, University of Piraeus, 18534 Piraeus, Greece
    Copyright: © Katsarou et al. This is an open access article distributed under the terms of Creative Commons Attribution License.
  • Pages: 1899-1907
    |
    Published online on: September 18, 2020
       https://doi.org/10.3892/ijmm.2020.4732
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

An association of vitamin D receptor (VDR) polymorphisms and vitiligo has been suggested. However, previous studies have reported contradictory results while including limited data among Caucasians. The aim of this single‑center study was to evaluate the effect of three common VDR gene polymorphisms (FokI, TaqI and BsmI) on susceptibility and clinical aspects of vitiligo in a Southeastern European Caucasian population. A total of 110 unrelated vitiligo cases and 509 general population controls were enrolled from October 2018 to November 2019. Genomic DNA was extracted from whole blood after de‑identification and anonymization of the samples and genotyped for the selected VDR polymorphisms by the qPCR (melting curve analysis). Subgroup analysis by clinical features among subsets of patients indicated that, compared to subjects with the FokI TT genotype or T allele, carriers of the FokI CC genotype or C allele exhibited significantly decreased risk of developing vitiligo before the age of 30 [TT vs. CC: odds ratio (OR)=0.286, 95% confidence interval (CI): 0.083‑0.984, P=0.041; T vs. C: OR=0.545, 95% CI: 0.313‑0.948, P=0.031]. Intra‑patient analysis also revealed that, compared to T allele, the presence of TaqI C allele was adversely associated with the incidence of concurrent leukotrichia (T vs. C: OR=1.874, 95% CI: 1.018‑3.451, P=0.042). Comparisons between the case and control groups showed no evidence to support an association between susceptibility to vitiligo and the VDR BsmI, TaqI, and FokI polymorphisms in this cohort. Thus, the studied VDR polymorphisms might indirectly impact the clinical course and treatment decision‑making despite their lack of association with vitiligo per se. Further research with larger sample sizes, especially across Caucasian individuals, should be performed to confirm these findings.
View Figures

Figure 1

Figure 2

View References

1 

Ezzedine K, Eleftheriadou V, Whitton M and van Geel N: Vitiligo. Lancet. 386:74–84. 2015. View Article : Google Scholar : PubMed/NCBI

2 

Roberts GHL, Santorico SA and Spritz RA: The genetic architecture of vitiligo. Pigment Cell Melanoma Res. 33:8–15. 2020. View Article : Google Scholar

3 

Wu J, Zhou M, Wan Y and Xu A: CD8+ T cells from vitiligo perilesional margins induce autologous melanocyte apoptosis. Mol Med Rep. 7:237–241. 2013. View Article : Google Scholar

4 

Spritz RA and Andersen GH: Genetics of Vitiligo. Dermatol Clin. 35:245–255. 2017. View Article : Google Scholar : PubMed/NCBI

5 

Krasanakis T, Nikolouzakis TK, Sgantzos M, Mariolis-Sapsakos T, Souglakos J, Spandidos DA, Tsitsimpikou C, Tsatsakis A and Tsiaoussis J: Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review). Oncol Rep. 42:2228–2244. 2019.PubMed/NCBI

6 

Barbu CG, Arsene AL, Florea S, Albu A, Sirbu A, Martin S, Nicolae AC, Burcea-Dragomiroiu GTA, Popa DE, Velescu BS, et al: Cardiovascular risk assessment in osteo-porotic patients using osteoprotegerin as a reliable predictive biochemical marker. Mol Med Rep. 16:6059–6067. 2017. View Article : Google Scholar : PubMed/NCBI

7 

Murdaca G, Tonacci A, Negrini S, Greco M, Borro M, Puppo F and Gangemi S: Emerging role of vitamin D in autoimmune diseases: An update on evidence and therapeutic implications. Autoimmun Rev. 18:1023502019. View Article : Google Scholar : PubMed/NCBI

8 

Kechichian E and Ezzedine K: Vitamin D and the skin: an update for dermatologists. Am J Clin Dermatol. 19:223–235. 2018. View Article : Google Scholar

9 

Upala S and Sanguankeo A: Low 25-hydroxyvitamin D levels are associated with vitiligo: A systematic review and meta-analysis. Photodermatol Photoimmunol Photomed. 32:181–190. 2016. View Article : Google Scholar : PubMed/NCBI

10 

Birlea SA, Costin GE and Norris DA: New insights on therapy with vitamin D analogs targeting the intracellular pathways that control repigmentation in human vitiligo. Med Res Rev. 29:514–546. 2009. View Article : Google Scholar : PubMed/NCBI

11 

Parsad D and Kanwar AJ: Topical vitamin D analogues in the treatment of vitiligo. Pigment Cell Melanoma Res. 22:487–488. 2009. View Article : Google Scholar : PubMed/NCBI

12 

Siokas V, Aslanidou P, Aloizou AM, Peristeri E, Stamati P, Liampas I, Arseniou S, Drakoulis N, Aschner M, Tsatsakis A, et al: Does the CD33 rs3865444 polymorphism confer susceptibility to Alzheimer's disease? J Mol Neurosci. 70:851–860. 2020. View Article : Google Scholar : PubMed/NCBI

13 

Dardiotis E, Aloizou AM, Siokas V, Tsouris Z, Rikos D, Marogianni C, Aschner M, Kovatsi L, Bogdanos DP and Tsatsakis A: Paraoxonase-1 genetic polymorphisms in organo-phosphate metabolism. Toxicology. 411:24–31. 2019. View Article : Google Scholar

14 

Anbar TS, Hegazy RA, Picardo M and Taieb A: Beyond vitiligo guidelines: Combined stratified/personalized approaches for the vitiligo patient. Exp Dermatol. 23:219–223. 2014. View Article : Google Scholar : PubMed/NCBI

15 

Nejentsev S, Godfrey L, Snook H, Rance HS, Walker NM, Lam AC, Guja C, Ionescu-Tirgoviste C, Undlien DE, et al: Comparative high-resolution analysis of linkage disequilibrium and tag single nucleotide polymorphisms between populations in the vitamin D receptor gene. Hum Mol Genet. 13:1633–1639. 2004. View Article : Google Scholar : PubMed/NCBI

16 

Li L, Wu Y, Li L, Cai YF, Geng L, Gao XH and Chen HD: Association of ApaI and BsmI polymorphisms with vitiligo risk: A meta-analysis. Clin Exp Dermatol. 40:794–803. 2015. View Article : Google Scholar : PubMed/NCBI

17 

Uitterlinden AG, Fang Y, Van Meurs JB, Pols HA and Van Leeuwen JP: Genetics and biology of vitamin D receptor polymorphisms. Gene. 338:143–156. 2004. View Article : Google Scholar : PubMed/NCBI

18 

Zhang JZ, Wang M, Ding Y, Gao F, Feng YY, Yakeya B, Wang P, Wu XJ, Hu FX, Xian J, et al: Vitamin D receptor gene polymorphism, serum 25-hydroxyvitamin D levels, and risk of vitiligo: A meta-analysis. Medicine (Baltimore). 97:e115062018. View Article : Google Scholar

19 

Lee YH: Vitamin D receptor ApaI, TaqI, BsmI, and FokI polymorphisms and psoriasis susceptibility: An updated meta-analysis. Clin Exp Dermatol. 44:498–505. 2019. View Article : Google Scholar

20 

Heine G, Hoefer N, Franke A, Nöthling U, Schumann RR, Hamann L and Worm M: Association of vitamin D receptor gene polymorphisms with severe atopic dermatitis in adults. Br J Dermatol. 168:855–858. 2013. View Article : Google Scholar

21 

Ezzedine K, Lim HW, Suzuki T, Katayama I, Hamzavi I, Lan CCE, Goh BK, Anbar T, Silva de Castro C, Lee AY, et al: Vitiligo Global Issue Consensus Conference Panelists: Revised classification/nomenclature of vitiligo and related issues: The Vitiligo Global Issues Consensus Conference. Pigment Cell Melanoma Res. 25:E1–E13. 2012. View Article : Google Scholar : PubMed/NCBI

22 

Aydıngöz IE, Bingül I, Doğru-Abbasoğlu S, Vural P and Uysal M: Analysis of vitamin D receptor gene polymorphisms in vitiligo. Dermatology. 224:361–368. 2012. View Article : Google Scholar

23 

Birlea S, Birlea M, Cimponeriu D, Apostol P, Cosgarea R, Gavrila L, Tigan S, Costin G and Das P: Autoimmune diseases and vitamin D receptor Apa-I polymorphism are associated with vitiligo in a small inbred Romanian community. Acta Derm Venereol. 86:209–214. 2006. View Article : Google Scholar : PubMed/NCBI

24 

Hassan I, Bhat YJ, Majid S, Sajad P, Rasool F, Malik RA and Ul Haq I: Association of vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D levels in vitiligo - a case-control study. Indian Dermatol Online J. 10:131–138. 2019.PubMed/NCBI

25 

Li K, Shi Q, Yang L, Li X, Liu L, Wang L, Li Q, Wang G, Li CY and Gao TW: The association of vitamin D receptor gene polymorphisms and serum 25-hydroxyvitamin D levels with generalized vitiligo. Br J Dermatol. 167:815–821. 2012. View Article : Google Scholar : PubMed/NCBI

26 

Ochoa-Ramírez LA, Díaz-Camacho SP, Becerra-Loaiza DS, Verdugo-Nieto L, Muñoz-Estrada VF, Servín-Vázquez LA, Osuna-Ramírez I, Rodríguez-Millán J and Velarde-Félix JS: Catalase but not vitamin D receptor gene polymorphisms are associated with nonsegmental vitiligo in Northwestern Mexicans. Int J Dermatol. 58:1264–1269. 2019. View Article : Google Scholar : PubMed/NCBI

27 

Sobeih S, Mashaly HM, Gawdat H, Amr K, Hamid MF and Shaalan E: Evaluation of the correlation between serum levels of vitamin D and vitamin D receptor gene polymorphisms in an Egyptian population. Int J Dermatol. 55:1329–1335. 2016. View Article : Google Scholar : PubMed/NCBI

28 

Lee DY, Kim CR, Park JH and Lee JH: The incidence of leukotrichia in segmental vitiligo: Implication of poor response to medical treatment. Int J Dermatol. 50:925–927. 2011. View Article : Google Scholar : PubMed/NCBI

29 

van Geel N, Grine L, De Wispelaere P, Mertens D, Prinsen CAC and Speeckaert R: Clinical visible signs of disease activity in vitiligo: A systematic review and meta-analysis. J Eur Acad Dermatol Venereol. 33:1667–1675. 2019. View Article : Google Scholar : PubMed/NCBI

30 

Saccone D, Asani F and Bornman L: Regulation of the vitamin D receptor gene by environment, genetics and epigenetics. Gene. 561:171–180. 2015. View Article : Google Scholar : PubMed/NCBI

31 

Wang D, Xu X, Ma H, Yue X, Li C and Zhu W: Optimization of the method for the culture of melanocyte precursors from hair follicles and their activation by 1,25-dihydroxyvitamin D3. Exp Ther Med. 6:967–972. 2013. View Article : Google Scholar : PubMed/NCBI

32 

Katsarou MS, Karathanasopoulou A, Andrianopoulou A, Desiniotis V, Tzinis E, Dimitrakis E, Lagiou M, Charmandari E, Aschner M, Tsatsakis AM, et al: Beta 1, Beta 2 and Beta 3 adrenergic receptor gene polymorphisms in a Southeastern European population. Front Genet. 9:5602018. View Article : Google Scholar : PubMed/NCBI

33 

Katsarou MS, Papasavva M, Latsi R, Toliza I, Gkaros AP, Papakonstantinou S, Gatzonis S, Mitsikostas DD, Kovatsi L, Izotov BN, et al: Population-based analysis of cluster headache-associated genetic polymorphisms. J Mol Neurosci. 65:367–376. 2018. View Article : Google Scholar : PubMed/NCBI

34 

Katsarou MS, Latsi R, Papasavva M, Demertzis N, Kalogridis T, Tsatsakis AM, Spandidos DA and Drakoulis N: Population-based analysis of the frequency of HFE gene polymorphisms: Correlation with the susceptibility to develop hereditary hemochromatosis. Mol Med Rep. 14:630–636. 2016. View Article : Google Scholar : PubMed/NCBI

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Katsarou MS, Sidiropoulou P, Ieronymaki D, Mastraftsi S, Sifaki M, Xenos K, Nosyrev A, Kovatsi L, Spandidos DA, Lagiou M, Lagiou M, et al: Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population. Int J Mol Med 46: 1899-1907, 2020.
APA
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K. ... Nicolaidou, E. (2020). Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population. International Journal of Molecular Medicine, 46, 1899-1907. https://doi.org/10.3892/ijmm.2020.4732
MLA
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K., Nosyrev, A., Kovatsi, L., Spandidos, D. A., Lagiou, M., Dagklis, C., Gregoriou, S., Tagka, A., Rigopoulos, D., Drakoulis, N., Nicolaidou, E."Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population". International Journal of Molecular Medicine 46.5 (2020): 1899-1907.
Chicago
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K., Nosyrev, A., Kovatsi, L., Spandidos, D. A., Lagiou, M., Dagklis, C., Gregoriou, S., Tagka, A., Rigopoulos, D., Drakoulis, N., Nicolaidou, E."Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population". International Journal of Molecular Medicine 46, no. 5 (2020): 1899-1907. https://doi.org/10.3892/ijmm.2020.4732
Copy and paste a formatted citation
x
Spandidos Publications style
Katsarou MS, Sidiropoulou P, Ieronymaki D, Mastraftsi S, Sifaki M, Xenos K, Nosyrev A, Kovatsi L, Spandidos DA, Lagiou M, Lagiou M, et al: Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population. Int J Mol Med 46: 1899-1907, 2020.
APA
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K. ... Nicolaidou, E. (2020). Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population. International Journal of Molecular Medicine, 46, 1899-1907. https://doi.org/10.3892/ijmm.2020.4732
MLA
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K., Nosyrev, A., Kovatsi, L., Spandidos, D. A., Lagiou, M., Dagklis, C., Gregoriou, S., Tagka, A., Rigopoulos, D., Drakoulis, N., Nicolaidou, E."Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population". International Journal of Molecular Medicine 46.5 (2020): 1899-1907.
Chicago
Katsarou, M., Sidiropoulou, P., Ieronymaki, D., Mastraftsi, S., Sifaki, M., Xenos, K., Nosyrev, A., Kovatsi, L., Spandidos, D. A., Lagiou, M., Dagklis, C., Gregoriou, S., Tagka, A., Rigopoulos, D., Drakoulis, N., Nicolaidou, E."Impact of vitamin D receptor gene polymorphisms on vitiligo susceptibility and clinical features in a Southeastern European Caucasian population". International Journal of Molecular Medicine 46, no. 5 (2020): 1899-1907. https://doi.org/10.3892/ijmm.2020.4732
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team