Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review)

  • Authors:
    • Gianmarco Stati
    • Silvia Sancilio
    • Mariangela Basile
    • Antonio Angelini
    • Roberta Di Pietro
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  • Published online on: September 25, 2020     https://doi.org/10.3892/ijmm.2020.4738
  • Pages: 1951-1957
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Abstract

Curcumin has been used since ancient times as a treatment for a wide range of pathologies. For centuries, it has been considered to be an effective aid for common human diseases. Curcuma longa has been reported to possess various beneficial properties and actions, including anti‑inflammatory, proapoptotic, antiangiogenic and cortisone‑like actions. Pterygium is a degenerative disorder of the conjunctiva indicative of a strong inflammatory condition that requires surgical treatment, which often results in disfiguring sclerocorneal scars. The delay in the healing of superficial corneal wounds caused by topical administration of light‑cortisone results in improved restoration of corneal functions and anatomy compared with physiological healing processes. The present review is focused on the medicinal properties of curcumin, the main component of Curcuma longa extract, in particular its strong cortisone‑like effect, and its potential use for the prevention and treatment of sclerocorneal scars resulting from pterygium surgical excision.
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December-2020
Volume 46 Issue 6

Print ISSN: 1107-3756
Online ISSN:1791-244X

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Spandidos Publications style
Stati G, Sancilio S, Basile M, Angelini A and Di Pietro R: Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review). Int J Mol Med 46: 1951-1957, 2020
APA
Stati, G., Sancilio, S., Basile, M., Angelini, A., & Di Pietro, R. (2020). Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review). International Journal of Molecular Medicine, 46, 1951-1957. https://doi.org/10.3892/ijmm.2020.4738
MLA
Stati, G., Sancilio, S., Basile, M., Angelini, A., Di Pietro, R."Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review)". International Journal of Molecular Medicine 46.6 (2020): 1951-1957.
Chicago
Stati, G., Sancilio, S., Basile, M., Angelini, A., Di Pietro, R."Curcuma longa aqueous extract: A potential solution for the prevention of corneal scarring as a result of pterygium surgical excision (Review)". International Journal of Molecular Medicine 46, no. 6 (2020): 1951-1957. https://doi.org/10.3892/ijmm.2020.4738