|
1
|
Ma J, Rubin BK and Voynow JA: Mucins,
mucus, and goblet cells. Chest. 154:169–176. 2018. View Article : Google Scholar
|
|
2
|
Bonser LR and Erle DJ: Airway mucus and
asthma: The role of MUC5AC and MUC5B. J Clin Med. 6:1122017.
View Article : Google Scholar :
|
|
3
|
Thornton DJ, Rousseau K and McGuckin MA:
Structure and function of the polymeric mucins in airways mucus.
Annu Rev Physiol. 70:459–486. 2008. View Article : Google Scholar
|
|
4
|
Bae CH, Na HG, Choi YS, Song SY and Kim
YD: Clusterin induces MUC5AC expression via activation of NF-κB in
human airway epithelial cells. Clin Exp Otorhinolaryngol.
11:124–132. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Song KS, Yoon JH, Kim KS and Ahn DW:
c-Ets1 inhibits the interaction of NF-κB and CREB, and
downregulates IL-1β-induced MUC5A coverproduction during airway
inflammation. Mucosal Immunol. 5:207–215. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Martino MB, Jones L, Brighton B, Ehre C,
Abdulah L, Davis CW, Ron D, O'Neal WK and Ribeiro CM: The ER stress
transducer IRE1β is required for airway epithelial mucin
production. Mucosal Immunol. 6:639–654. 2013. View Article : Google Scholar
|
|
7
|
Wang X, Yang X, Li Y, Wang X, Zhang Y, Dai
X, Niu B, Wu J, Yuan X, Xiong A, et al: Lyn kinase represses mucus
hypersecretion by regulating IL-13-induced endoplasmic reticulum
stress in asthma. EBioMedicine. 15:137–149. 2017. View Article : Google Scholar :
|
|
8
|
Safra M, Ben-Hamo S, Kenyon C and
Henis-Korenblit S: The IRE-1 ER stress-response pathway is required
for normal secretory-protein metabolism in C. elegans J Cell Sci.
126:4136–4146. 2013. View Article : Google Scholar
|
|
9
|
Kim S, Joe Y, Kim HJ, Kim YS, Jeong SO,
Pae HO, Ryter SW, Surh YJ and Chung HT: Endoplasmic reticulum
stress-induced IRE1α activation mediates cross-talk of GSK-3β and
XBP1 to regulate inflammatory cytokine production. J Immunol.
194:4498–4506. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Deo SH, Jenkins NT, Padilla J, Parrish AR
and Fadel PJ: Norepinephrine increases NADPH oxidase-derived
superoxide in human peripheral bloodmonuclear cells via
α-adrenergic receptors. Am J Physiol Regul Integr Comp Physiol.
305:R1124–R1132. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Basseri S, Lhoták S, Sharma AM and Austin
RC: The chemical chaperone 4-phenylbutyrate inhibits adipogenesis
by modulating the unfolded protein response. J Lipid Res.
50:2486–2501. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Halasi M, Wang M, Chavan TS, Gaponenko V,
Hay N and Gartel AL: ROS inhibitor N-acetyl-L-cysteine antagonizes
the activity of proteasome inhibitors. Biochem J. 454:201–208.
2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
14
|
Kohri K, Ueki IF and Nadel JA: Neutrophil
elastase induces mucin production by ligand-dependent epidermal
growth factor receptor activation. Am J Physiol Lung Cell Mol
Physiol. 283:L531–L540. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Shao MX and Nadel JA: Neutrophil elastase
induces MUC5AC mucin production in human airway epithelial cells
via a cascade involving protein kinase C, reactive oxygen species,
and TNF-alpha-converting enzyme. J Immunol. 175:4009–4016. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Voynow JA, Fischer BM, Malarkey DE, Burch
LH, Wong T, Longphre M, Ho SB and Foster WM: Neutrophil elastase
induces mucus cell metaplasia in mouse lung. Am J Physiol Lung Cell
Mol Physiol. 287:L1293–L1302. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Park JA, Sharif AS, Shiomi T, Kobzik L,
Kasahara DI, Tschumperlin DJ, Voynow J and Drazen JM: Human
neutrophil elastase-mediated goblet cell metaplasia is attenuated
in TACE-deficient mice. Am J Physiol Lung Cell Mol Physiol.
304:L701–L707. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Mennerich D, Kellokumpu S and Kietzmann T:
Hypoxia and reactive oxygen species as modulators of endoplasmic
reticulum and golgi homeostasis. Antioxid Redox Signal. 30:113–137.
2019. View Article : Google Scholar
|
|
19
|
Zeeshan HM, Lee GH, Kim HR and Chae HJ:
Endoplasmic reticulum stress and associated ROS. Int J Mol Sci.
17:3272016. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Zeng M, Sang W, Chen S, Chen R, Zhang H,
Xue F, Li Z, Liu Y, Gong Y, Zhang H and Kong X: 4-PBA inhibits
LPS-induced inflammation through regulating ER stress and autophagy
in acute lung injury models. Toxicol Lett. 5(271): 26–37. 2017.
View Article : Google Scholar
|
|
21
|
Martinon F, Chen X, Lee AH and Glimcher
LH: Toll-like receptor activation of XBP1 regulates innate immune
responses in macrophages. Nat Immunol. 11:411–418. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Keestra-Gounder AM, Byndloss MX, Seyffert
N, Young BM, Chávez-Arroyo A, Tsai AY, Cevallos SA, Winter MG, Pham
OH, Tiffany CR, et al: NOD1 and NOD2 signalling links ER stress
with inflammation. Nature. 532:394–397. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Wang Y, Wu ZZ and Wang W: Inhibition of
endoplasmic reticulum stress alleviates cigarette smoke-induced
airway inflammation and emphysema. Oncotarget. 8:77685–77695. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kunchithapautham K, Atkinson C and Rohrer
B: Smoke exposure causes endoplasmic reticulum stress and lipid
accumulation in retinal pigment epithelium through oxidative stress
and complement activation. J Biol Chem. 289:14534–14546. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Li XZ, Xu C and Yang PX: c-Jun
NH2-terminal kinase 1/2 and endoplasmic reticulum stress as
interdependent and reciprocal causation in diabetic embryopathy.
Diabetes. 62:599–608. 2013. View Article : Google Scholar :
|
|
26
|
Oakes SA and Papa FR: The role of
endoplasmic reticulum stress in human pathology. Annu Rev Pathol.
10:173–194. 2015. View Article : Google Scholar
|
|
27
|
Cao SS, Luo KL and Shi L: Endoplasmic
reticulum stress interacts with inflammation in human diseases. J
Cell Physiol. 231:288–294. 2016. View Article : Google Scholar
|
|
28
|
Mijošek V, Lasitschka F, Warth A, Zabeck
H, Dalpke AH and Weitnauer M: Endoplasmic reticulum stress is a
danger signal promoting innate inflammatory responses in bronchial
epithelial cells. J Innate Immun. 8:464–478. 2016. View Article : Google Scholar
|
|
29
|
Liu ZW, Zhu HT, Chen KL, Dong X, Wei J,
Qiu C and Xue JH: Protein kinase RNA-like endoplasmic reticulum
kinase (PERK) signaling pathway plays a major role in reactive
oxygen species (ROS)-mediated endoplasmic reticulum stress-induced
apoptosis in diabetic cardiomyopathy. Cardiovasc Diabetol.
12:1582013. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Ochoa CD, Wu RF and Terada LS: ROS
signaling and ER stress in cardiovascular disease. Mol Aspects Med.
63:18–29. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Saco TV, Breitzig MT, Lockey RF and
Kolliputi N: Epigenetics of mucus hypersecretion in chronic
respiratory diseases. Am J Respir Cell Mol Biol. 58:299–309. 2018.
View Article : Google Scholar :
|
|
32
|
Peñaranda Fajardo NM, Meijer C and Kruyt
FA: The endoplasmic reticulum stress/unfolded protein response in
gliomagenesis, tumor progression and as a therapeutic target in
glioblastoma. Biochem Pharmacol. 118:1–8. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Bright MD, Itzhak DN, Wardell CP, Morgan
GJ and Davies FE: Cleavage of BLOC1S1 mRNA by IRE1 is sequence
specific, temporally separate from XBP1 splicing, and dispensable
for cell viability under acute endoplasmic reticulum stress. Mol
Cell Biol. 35:2186–2202. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Ron D and Walter P: Signal integration in
the endoplasmic reticulum unfolded protein response. Nat Rev Mol
Cell Biol. 8:519–529. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Jiang D, Niwa M and Koong AC: Targeting
the IRE1α-XBP1 branch of the unfolded protein response in human
diseases. Semin Cancer Biol. 33:48–56. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Cao SS and Kaufman RJ: Unfolded protein
response. Curr Biol. 22:R622–R626. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Hetz C: The unfolded protein response:
Controlling cell fate decisions under ER stress and beyond. Nat Rev
Mol Cell Biol. 13:89–102. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Wu R, Zhang QH, Lu YJ, Ren K and Yi GH:
Involvement of the IRE1α-XBP1 pathway and XBP1s-dependent
transcriptional reprogramming in metabolic diseases. DNA Cell Biol.
34:6–18. 2015. View Article : Google Scholar :
|
|
39
|
Chen C and Zhang X: IRE1α-XBP1 pathway
promotes melanoma progression by regulating IL-6/STAT3 signaling. J
Transl Med. 15:422017. View Article : Google Scholar
|
|
40
|
Urano F, Bertolotti A and Ron D: IRE1 and
efferent signaling from the endoplasmic reticulum. J Cell Sci.
21:3697–3702. 2000.
|
|
41
|
Park SH, Gong JH, Choi YJ, Kang MK, Kim YH
and Kang YH: Kaempferol inhibits endoplasmic reticulum
stress-associated mucus hypersecretion in airway epithelial cells
and ovalbumin-sensitized mice. PLoS One. 10:e01435262015.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Iwakoshi NN, Lee AH, Vallabhajosyula P,
Otipoby KL, Rajewsky K and Glimcher LH: Plasma cell differentiation
and the unfolded protein response intersect at the transcription
factor XBP1. Nat Immunol. 4:321–329. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Glimcher LH: XBP1: The last two decades.
Ann Rheum Dis. 69(Suppl 1): S67–S71. 2010. View Article : Google Scholar
|
|
44
|
Wang G, Xu Z, Wang R, Al-Hijji M, Salit J,
Strulovici-Barel Y, Tilley AE, Mezey JG and Crystal RG: Genes
associated with MUC5AC expression in small airway epithelium of
human smokers and non-smokers. BMC Med Genomics. 5:212012.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Yoshida H, Okada T, Haze K, Yanagi H, Yura
T, Negishi M and Mori K: ATF6 activated by proteolysis binds in the
presence of NF-Y (CBF) directly to the cis-acting element
responsible for the mammalian unfolded protein response. Mol Cell
Biol. 20:6755–6767. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Spaan CN, Smit WL, van Lidth de Jeude JF,
Meijer BJ, Muncan V, van den Brink GR and Heijmans J: Expression of
UPR effector proteins ATF6 and XBP1 reduce colorectal cancer cell
proliferation and stemness by activating PERK signaling. Cell Death
Dis. 10:4902019. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Gonen N, Sabath N, Burge CB and Shalgi R:
Widespread PERK-dependent repression of ER targets in response to
ER stress. Sci Rep. 9:43302019. View Article : Google Scholar : PubMed/NCBI
|
