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International Journal of Molecular Medicine
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International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
May-2021 Volume 47 Issue 5

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Hsa_circ_0032463 acts as the tumor promoter in osteosarcoma by regulating the miR‑330‑3p/PNN axis

Guanghua Qin, Xuejian Wu
Article Number: 92
Published online on: 30 March 2021

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Uncarboxylated osteocalcin reverses the high glucose‑induced inhibition of the osteogenic differentiation of MC3T3E1 cells via the GPRC6A/cAMP/PKA/AMPK signaling pathway

Luyao Ma, Fangzi Gong, Jiaojiao Xu, Jianhong Yang
Article Number: 91
Published online on: 29 March 2021

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Article Open Access

Dexmedetomidine suppresses the development of abdominal aortic aneurysm by downregulating the mircoRNA‑21/PDCD 4 axis

Qi Yu, Qianqian Li, Xinglong Yang, Qiang Liu, Jun Deng, Yanping Zhao, Ruilin Hu, Min Dai
Article Number: 90
Published online on: 29 March 2021

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The potential role of necroptosis in clinical diseases (Review)

Wenli Dai, Jin Cheng, Xi Leng, Xiaoqing Hu, Yingfang Ao
Article Number: 89
Published online on: 26 March 2021

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Review Open Access

Role of circRNAs in viral infection and their significance for diagnosis and treatment (Review)

Yuyao Mo, Yuze Liu, Anni Lu, Hanyi Zhang, Lijun Tang
Article Number: 88
Published online on: 24 March 2021

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Article Open Access

FXII regulates the formation of deep vein thrombosis via the PI3K/AKT signaling pathway in mice

Yan Meng, Qian Yin, Qiang Ma, Hao Qin, Junbo Zhang, Bo Zhang, Honggang Pang, Hongyan Tian
Article Number: 87
Published online on: 23 March 2021

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Article Open Access

Lipoxin A4 protects against paraquat‑induced acute lung injury by inhibiting the TLR4/MyD88‑mediated activation of the NF‑κB and PI3K/AKT pathways

Yuhua Li, Na Wang, Zhongliang Ma, Yunwen Wang, Yuan Yuan, Zhitao Zhong, Yi Hong, Min Zhao
Article Number: 86
Published online on: 19 March 2021

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Article Open Access

Ceramide induces the apoptosis of non‑small cell lung cancer cells through the Txnip/Trx1 complex

Yining Shi, Yongmei Jin, Fangfang Liu, Jianjun Jiang, Jiyu Cao, Youjin Lu, Jin Yang
Article Number: 85
Published online on: 19 March 2021

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Article Open Access

Long non‑coding RNA MIR4713HG aggravates malignant behaviors in oral tongue squamous cell carcinoma via binding with microRNA let‑7c‑5p

Bo Jia, Xianghuai Zheng, Xiaoling Qiu, Xiao Jiang, Jingpeng Liu, Zhijie Huang, Shijian Xiang, Guodong Chen, Jianjiang Zhao
Article Number: 84
Published online on: 18 March 2021

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Review Open Access

Critical role of mass spectrometry proteomics in tear biomarker discovery for multifactorial ocular diseases (Review)

Jessica Yuen Wuen Ma, Ying Hon Sze, Jing Fang Bian, Thomas Chuen Lam
Article Number: 83
Published online on: 18 March 2021

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Review Open Access

Insight into the roles of melatonin in bone tissue and bone‑related diseases (Review)

Xiaofeng Lu, Shaoling Yu, Guangjin Chen, Wenhao Zheng, Jinfeng Peng, Xiaofei Huang, Lili Chen
Article Number: 82
Published online on: 17 March 2021

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Article Open Access

Endoplasmic reticulum stress/XBP1 promotes airway mucin secretion under the influence of neutrophil elastase

Xiaoyan Xu, Qi Li, Liang Li, Man Zeng, Xiangdong Zhou, Zhaozhong Cheng
Article Number: 81
Published online on: 11 March 2021

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Article Open Access

Knockdown of long non‑coding RNA DLEU2 suppresses idiopathic pulmonary fibrosis by regulating the microRNA‑369‑3p/TRIM2 axis

Hengzhong Yi, Danlin Luo, Yangbao Xiao, Di Jiang
Article Number: 80
Published online on: 11 March 2021

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Article Open Access

Ectodermal‑neural cortex 1 affects the biological function of lung cancer through the MAPK pathway

Chengwei Wu, Xianghai Wang, Xingwei Wu, Xingwu Chen
Article Number: 79
Published online on: 10 March 2021

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Article Open Access

Upregulated long non‑coding RNA LincIN promotes tumor progression via the regulation of nuclear factor 90/microRNA‑7/HOXB13 in esophageal squamous cell carcinoma

Zhibo Tan, Peitao Zhou, Zhenru Zhu, Ying Wang, Zeqin Guo, Mengying Shen, Yazhi Xiao, Weixi Shen, Dehua Wu
Article Number: 78
Published online on: 10 March 2021

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Article Open Access

TGIF1 plays a carcinogenic role in esophageal squamous cell carcinoma through the Wnt/β‑catenin and Akt/mTOR signaling pathways

Lingling Kong, Yang Yu, Hui Guan, Liyang Jiang, Fenghao Sun, Xiaolin Li, Wei Huang, Baosheng Li
Article Number: 77
Published online on: 08 March 2021

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Article Open Access

Radiation induces primary osteocyte senescence phenotype and affects osteoclastogenesis in vitro

Yuyang Wang, Linshan Xu, Jianping Wang, Jiangtao Bai, Jianglong Zhai, Guoying Zhu
Article Number: 76
Published online on: 05 March 2021

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Therapeutic potential of curcumin in diabetic retinopathy (Review)

Jian Yang, Xiao Miao, Feng-Juan Yang, Jin-Feng Cao, Xin Liu, Jin-Ling Fu, Guan-Fang Su
Article Number: 75
Published online on: 04 March 2021

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Article

Knockdown of long non‑coding RNA HCP5 suppresses the malignant behavior of retinoblastoma by sponging miR‑3619‑5p to target HDAC9

Yuguang Zhu, Fengqin Hao
Article Number: 74
Published online on: 03 March 2021

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Estrogen disorders: Interpreting the abnormal regulation of aromatase in granulosa cells (Review)

Ting Liu, Yifei Huang, Hui Lin
Article Number: 73
Published online on: 02 March 2021

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Article

LINCS gene expression signature analysis revealed bosutinib as a radiosensitizer of breast cancer cells by targeting eIF4G1

Sai Hu, Dafei Xie, Pingkun Zhou, Xiaodan Liu, Xiaoyao Yin, Bo Huang, Hua Guan
Article Number: 72
Published online on: 02 March 2021

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Adipose tissue and age‑dependent insulin resistance: New insights into WAT browning (Review)

Chuanlong Wu, Pei Yu, Ruixin Sun
Article Number: 71
Published online on: 02 March 2021

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Article Open Access

circNRIP1 facilitates keloid progression via FXR1‑mediated upregulation of miR‑503‑3p and miR‑503‑5p

Baolin Wang, Hang Yin, Hongmei Zhang, Tiantian Wang
Article Number: 70
Published online on: 01 March 2021

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Article

miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG Retraction in /10.3892/ijmm.2026.5743

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 69
Published online on: 01 March 2021

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Article Open Access

Alantolactone suppresses the metastatic phenotype and induces the apoptosis of glioblastoma cells by targeting LIMK kinase activity and activating the cofilin/G‑actin signaling cascade

Xun Wang, Shuang Zou, Tong Ren, Li-Jun Zhao, Li-Fei Yu, Xiang-Yu Li, Xin Yan, Li-Jun Zhang
Article Number: 68
Published online on: 01 March 2021

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Article Open Access

Rosmarinic acid inhibits cell proliferation, migration, and invasion and induces apoptosis in human glioma cells

Yunsheng Liu, Xiangping Xu, Han Tang, Yuchen Pan, Bing Hu, Guodong Huang
Article Number: 67
Published online on: 26 February 2021

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Article Open Access

FUBP1 mediates the growth and metastasis through TGFβ/Smad signaling in pancreatic adenocarcinoma

Yue Zhang, Jinlian Chen, Nvshi Zhou, Yun Lu, Jingwen Lu, Xin Xing, Hua Chen, Xingxing Zhang
Article Number: 66
Published online on: 26 February 2021

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Article Open Access

MTSS1 inhibits colorectal cancer metastasis by regulating the CXCR4/CXCL12 signaling axis Retraction in /10.3892/ijmm.2023.5218

Lei Chen, Qiang Chen, Yongyou Wu, Minggao Zhu, Jia Hu, Zhixiang Zhuang
Article Number: 65
Published online on: 26 February 2021

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Journal Cover
March-2026 Volume 57 Issue 3

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

Article Open Access

Ginkgolide C alleviates atherosclerosis via activating Nrf2 to inhibit ROS‑dependent NLRP3 inflammasome activation

Rui Zhang
Article Number: 75
Published online on: 27 January 2026

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Review Open Access

MicroRNA‑microbiome cross‑kingdom networks drive inflammatory bowel disease through dynamic regulatory ecosystems (Review)

Liping Liang, Xiaoyan Liu, Bang Li, Huyi Lei, Zibo Tang, Shijie Mai, Chenghai Yang, Yongjian Zhou, Shaoheng Zhang, Le Liu
Article Number: 74
Published online on: 27 January 2026

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Mechanistic insights into pancreatic cancer progression from circadian rhythm disruption and gut microbiota dysbiosis (Review)

Yang Liu, Yongfeng Li, Heng Ma, Shichang Deng, Chao Cheng
Article Number: 73
Published online on: 26 January 2026

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Retraction Open Access

[Retracted] miR‑124‑3p inhibits the viability and motility of glioblastoma multiforme by targeting RhoG  

Shan Cai, Chao-Jia Shi, Jian-Xiang Lu, Yan-Pei Wang, Tian Yuan, Xiang-Peng Wang
Article Number: 72
Published online on: 26 January 2026

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Review Open Access

Natural products as multi‑target therapies for sepsis‑induced myocardial dysfunction (Review)

Fei Tang, Dong Liu, Shi-Chao Zhu, Hui-Min Zhou, Xue-Wen Qiu
Article Number: 71
Published online on: 22 January 2026

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Review Open Access

MTHFR‑folate axis as a modulator of the epigenetic landscape in autoimmune diseases (Review)

Pablo Michael Navarro‑Rodríguez, Ramón Francisco Bajeca‑Serrano, Francisco Javier Turrubiates‑Hernández, Hazael Ramiro Ceja‑Gálvez, Jorge Hernández‑Bello, Cristian Oswaldo Hernández‑Ramírez, Saúl Ramírez‑de Los Santos, José Francisco Muñoz‑Valle
Article Number: 70
Published online on: 22 January 2026

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Article Open Access

Natural compound 5,7,8‑trimethoxyflavone mitigates radiation‑induced lung injury by suppressing EMT and PI3K/Akt pathway

Cui-Cui Gong, Hua-Kang Li, Yuan-Zhen Mi, Jun-Yang Chen, Zeng-Yi Fang, Shun-Lian Fu, Li Quan, Bing Lin, Jin-Yi Lang, Qiu Chen, Ke Xu, Mei-Hua Chen
Article Number: 69
Published online on: 21 January 2026

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Review Open Access

Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)

Yuxing Li, Yujiao Gong, Jiaxing Zhao, Rensen Ran
Article Number: 68
Published online on: 21 January 2026

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Review Open Access

Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)

Ruo-Mei Cui, Mai Zheng, Jian-Bin Hong, Zheng-Xiang Wang, Yu-Fang Cun, Shu-Ji Gao, Yan-Lin Zhu, Zi-Bin Yang, Ming-Wei Liu
Article Number: 67
Published online on: 21 January 2026

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Expression of Concern Open Access

[Expression of Concern] Long non‑coding RNA SNHG20 promotes bladder cancer via activating the Wnt/β‑catenin signalling pathway

Qingsong Zhao, Saiyue Gao, Qingyan Du, Ye Liu
Article Number: 66
Published online on: 21 January 2026

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Review Open Access

Mangiferin in human disease: Multifaceted mechanisms and applications (Review)

Yaling Dai, Qiuling Huang, Mengquan Tan, Zhifu Wang, Cai Jiang, Zheng Liu, Shenghang Zhang, Siyuan Song
Article Number: 65
Published online on: 21 January 2026

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Article

Deciphering the CAF‑LCN2 axis: Key to overcoming anti‑PD‑L1 immunotherapy resistance in lung cancer

Dan Xiao, Jing Yang, Jianying Zhou, Zhenzhen Hu, Ting Zhang
Article Number: 64
Published online on: 19 January 2026

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Retraction Open Access

[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats

Zhen-Dong Zhu, Ji-Ming Ye, Xue-Mei Fu, Xue-Chang Wang, Ji-Yun Ye, Xin-Ran Wu, Peng Hua, Yu-Qiong Liao, Wei Xuan, Jin-Lan Duan, Wei-Yuan Li, Hui Fu, Zhong-Hua Xia, Xuan Zhang
Article Number: 63
Published online on: 19 January 2026

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Review Open Access

Beyond hepatic stellate cell heterogeneity: Resolving fibrosis, restoring regeneration (Review)

Chang Gao, Guiqing Chen, Hongyan Jia, Hong Zhu, Yun Cai, Dakai Yang, Kai Zhao
Article Number: 62
Published online on: 14 January 2026

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Correction Open Access

[Corrigendum] CDKN2A (p16INK4A) affects the anti‑tumor effect of CDK inhibitor in somatotroph adenomas

Yiyuan Chen, Zhenye Li, Qiuyue Fang, Hongyun Wang, Chuzhong Li, Hua Gao, Yazhuo Zhang
Article Number: 61
Published online on: 14 January 2026

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Review Open Access

Harnessing MSC‑derived exosomes to modulate the pathophysiology of ASD: Recent advances and therapeutic implications (Review)

Zhaojian Sun, Nouman Amjad, Majid Muhammad, Zhiyuan Li
Article Number: 60
Published online on: 13 January 2026

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Retraction Open Access

[Retracted] Mechanism of cell death induced by silica nanoparticles in hepatocyte cells is by apoptosis

Ye Yang, Xinjing Du, Qiang Wang, Jianwei Liu, Enguo Zhang, Linlin Sai, Cheng Peng, Martin F. Lavin, Abrey Jie Yeo, Xu Yang, Hua Shao, Zhongjun Du
Article Number: 59
Published online on: 12 January 2026

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Review Open Access

ZG16B: A key regulator of tumor progression and immune microenvironment modulation in cancer (Review)

Xing-Ming Chen, Yu-Bo Liang, Jin-Xiang Zuo, Zi-Sheng Yang, Le-Yu Zhang, Xin-Yu Zhang, Ping Wan, Yang Ke
Article Number: 58
Published online on: 09 January 2026

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Retraction Open Access

[Retracted] Silica nanoparticles induce cardiomyocyte apoptosis via the mitochondrial pathway in rats following intratracheal instillation

Zhongjun Du, Shangya Chen, Guanqun Cui, Ye Yang, Enguo Zhang, Qiang Wang, Martin F. Lavin, Abrey J. Yeo, Cunxiang Bo, Yu Zhang, Chao Li, Xiaoshan Liu, Xu Yang, Cheng Peng, Hua Shao
Article Number: 57
Published online on: 05 January 2026

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Review Open Access

Role of cuproptosis in digestive system tumors (Review)

Li Zhang, Yongpeng Cheng, Lulu Tang, Jiaxing Zhu, Biguang Tuo
Article Number: 56
Published online on: 02 January 2026

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Review Open Access

Environmental exposure to air pollution and climate: Intersecting the impact on ear and nose health and chemosensory function (Review)

Yu-Chen Zhang, Lei Zhang, Ping-Ting Zhou, Zi-Hui Xie, Wen-Jie Zhang, Min Fan, Yan-Xun Han, Ye-Hai Liu, Yu-Chen Liu
Article Number: 55
Published online on: 31 December 2025

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Review Open Access

Role and mechanisms of ferroptosis in cognitive impairment: From molecular pathways to therapeutic targets (Review)

Shenghui Ge, Deyue Kong, Shuyue Fan, Yi Luo, Xiao Yin, Zehua Jin, Wenqing Xia, Jianhua Ma
Article Number: 54
Published online on: 30 December 2025

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Review Open Access

The GPR124‑Wnt‑PPARγ regulatory axis: Molecular mechanisms and therapeutic implications in chronic inflammatory diseases (Review)

Ming-Wang Cui, Si-Yu Tao, Tao Wen, Zhu-Ling Guo
Article Number: 53
Published online on: 30 December 2025

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Review Open Access

Advances in RPGR gene therapy for X‑linked retinitis pigmentosa: From preclinical insights to clinical application (Review)

Yushan Long, Jia Qi, Wenliang Zhang, Huan Qin, Kai Yao
Article Number: 52
Published online on: 30 December 2025

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Journal Cover
April-2026 Volume 57 Issue 4

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Journal Metrics

Impact Factor: 5.8

CiteScore: 13.2

CiteScore Rank: Q1: #23/348 Biochemistry, Genetics and Molecular Biology

Source Normalized Impact per Paper (SNIP): 1.28

SCImago Journal Rank (SJR): 1.381

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