|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
El-Serag HB: Epidemiology of viral
hepatitis and hepatocellular carcinoma. Gastroenterology.
142:1264–1273. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Forner A, Llovet JM and Bruix J:
Hepatocellular carcinoma. Lancet. 379:1245–1255. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Bruix J and Sherman M; American
Association for the Study of Liver Diseases: Management of
hepatocellular carcinoma: An update. Hepatology. 53:1020–1022.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: The next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Ponting CP, Oliver PL and Reik W:
Evolution and functions of long noncoding RNAs. Cell. 136:629–641.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Ulitsky I and Bartel DP: lincRNAs:
Genomics, evolution, and mechanisms. Cell. 154:26–46. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Quinn JJ and Chang HY: Unique features of
long non-coding RNA biogenesis and function. Nat Rev Genet.
17:47–62. 2016. View Article : Google Scholar
|
|
9
|
Gutschner T, Hämmerle M, Eissmann M, Hsu
J, Kim Y, Hung G, Revenko A, Arun G, Stentrup M, Gross M, et al:
The noncoding RNA MALAT1 is a critical regulator of the metastasis
phenotype of lung cancer cells. Cancer Res. 73:1180–1189. 2013.
View Article : Google Scholar
|
|
10
|
Panzitt K, Tschernatsch MM, Guelly C,
Moustafa T, Stradner M, Strohmaier HM, Buck CR, Denk H, Schroeder
R, Trauner M and Zatloukal K: Characterization of HULC, a novel
gene with striking up-regulation in hepatocellular carcinoma, as
noncoding RNA. Gastroenterology. 132:330–342. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Nissan A, Stojadinovic A,
Mitrani-Rosenbaum S, Halle D, Grinbaum R, Roistacher M, Bochem A,
Dayanc BE, Ritter G, Gomceli I, et al: Colon cancer associated
transcript-1: A novel RNA expressed in malignant and pre-malignant
human tissues. Int J Cancer. 130:1598–1606. 2012. View Article : Google Scholar
|
|
12
|
Huarte M: The emerging role of lncRNAs in
cancer. Nat Med. 21:1253–1261. 2015. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang Y, Chen F, Zhao M, Yang Z, Li J,
Zhang S, Zhang W, Ye L and Zhang X: The long noncoding RNA HULC
promotes liver cancer by increasing the expression of the HMGA2
oncogene via sequestration of the microRNA-186. J Biol Chem.
292:15395–15407. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
He JH, Han ZP, Liu JM, Zhou JB, Zou MX, Lv
YB, Li YG and Cao MR: Overexpression of long non-coding RNA MEG3
inhibits proliferation of hepatocellular carcinoma Huh7 cells via
negative modulation of miRNA-664. J Cell Biochem. 118:3713–3721.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
He Y, Meng XM, Huang C, Wu BM, Zhang L, Lv
XW and Li J: Long noncoding RNAs: Novel insights into hepatocelluar
carcinoma. Cancer Letters. 344:20–27. 2014. View Article : Google Scholar
|
|
16
|
Gong X, Wei W, Chen L, Xia Z and Yu C:
Comprehensive analysis of long non-coding RNA expression profiles
in hepatitis B virus-related hepatocellular carcinoma. Oncotarget.
7:42422–42430. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Yang Y, Chen L, Gu J, Zhang H, Yuan J,
Lian Q, Lv G, Wang S, Wu Y, Yang YT, et al: Recurrently deregulated
lncRNAs in hepatocellular carcinoma. Nat Commun. 8:144212017.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Li D, Liu X, Zhou J, Hu J, Zhang D, Liu J,
Qiao Y and Zhan Q: Long noncoding RNA HULC modulates the
phosphorylation of YB-1 through serving as a scaffold of
extracellular signal-regulated kinase and YB-1 to enhance
hepatocarcinogenesis. Hepatology. 65:1612–1627. 2017. View Article : Google Scholar
|
|
19
|
He T, Zhang L, Kong Y, Huang Y, Zhang Y,
Zhou D, Zhou X, Yan Y, Zhang L, Lu S, et al: Long non-coding RNA
CASC15 is upregulated in hepatocellular carcinoma and facilitates
hepatocarcinogenesis. Int J Oncol. 51:1722–1730. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Du Y, Kong G, You X, Zhang S, Zhang T, Gao
Y, Ye L and Zhang X: Elevation of highly up-regulated in liver
cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell
proliferation via down-regulating p18. J Biol Chem.
287:26302–26311. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Quagliata L, Matter MS, Piscuoglio S,
Arabi L, Ruiz C, Procino A, Kovac M, Moretti F, Makowska Z,
Boldanova T, et al: Long noncoding RNA HOTTIP/HOXA13 expression is
associated with disease progression and predicts outcome in
hepatocellular carcinoma patients. Hepatology. 59:911–923. 2014.
View Article : Google Scholar :
|
|
22
|
Li SP, Xu HX, Yu Y, He JD, Wang Z, Xu YJ,
Wang CY, Zhang HM, Zhang RX, Zhang JJ, et al: lncRNA HULC enhances
epithelial-mesenchymal transition to promote tumorigenesis and
metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1
signaling pathway. Oncotarget. 7:42431–42446. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Cui M, Xiao Z, Wang Y, Zheng M, Song T,
Cai X, Sun B, Ye L and Zhang X: Long noncoding RNA HULC modulates
abnormal lipid metabolism in hepatoma cells through an
miR-9-mediated RXRA signaling pathway. Cancer Res. 75:846–857.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lu Z, Xiao Z, Liu F, Cui M, Li W, Yang Z,
Li J, Ye L and Zhang X: Long non-coding RNA HULC promotes tumor
angiogenesis in liver cancer by up-regulating sphingosine kinase 1
(SPHK1). Oncotarget. 7:241–254. 2016. View Article : Google Scholar :
|
|
25
|
Yu X, Zheng H, Chan MT and Wu WK: HULC: An
oncogenic long non-coding RNA in human cancer. J Cell Mol Med.
21:410–417. 2017. View Article : Google Scholar
|
|
26
|
Braconi C, Kogure T, Valeri N, Huang N,
Nuovo G, Costinean S, Negrini M, Miotto E, Croce CM and Patel T:
microRNA-29 can regulate expression of the long non-coding RNA gene
MEG3 in hepatocellular cancer. Oncogene. 30:4750–4756. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Zhu J, Liu S, Ye F, Shen Y, Tie Y, Zhu J,
Wei L, Jin Y, Fu H, Wu Y and Zheng X: Long noncoding RNA MEG3
interacts with p53 protein and regulates partial p53 target genes
in hepatoma cells. PLoS One. 10:e01397902015. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Moreno-Bueno G, Portillo F and Cano A:
Transcriptional regulation of cell polarity in EMT and cancer.
Oncogene. 27:6958–6969. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Yilmaz M and Christofori G: EMT, the
cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev.
28:15–33. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Peinado H, Olmeda D and Cano A: Snail, Zeb
and bHLH factors in tumour progression: An alliance against the
epithelial phenotype? Nat Rev Cancer. 7:415–428. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
De Craene B and Berx G: Regulatory
networks defining EMT during cancer initiation and progression. Nat
Rev Cancer. 13:97–110. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Lee JT: Epigenetic regulation by long
noncoding RNAs. Science. 338:1435–1439. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Nieto MA, Huang RY, Jackson RA and Thiery
JP: Emt: 2016. Cell. 166:21–45. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Yuan JH, Yang F, Wang F, Ma JZ, Guo YJ,
Tao QF, Liu F, Pan W, Wang TT, Zhou CC, et al: A long noncoding RNA
activated by TGF-beta promotes the invasion-metastasis cascade in
hepatocellular carcinoma. Cancer Cell. 25:666–681. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Zhou N, Si Z, Li T, Chen G, Zhang Z and Qi
H: Long non-coding RNA CCAT2 functions as an oncogene in
hepatocellular carcinoma, regulating cellular proliferation,
migration and apoptosis. Oncol Lett. 12:132–138. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Xu Y, Wang B, Zhang F, Wang A, Du X, Hu P,
Zhu Y and Fang Z: Long non-coding RNA CCAT2 is associated with poor
prognosis in hepatocellular carcinoma and promotes tumor metastasis
by regulating Snail2-mediated epithelial-mesenchymal transition.
Onco Targets Ther. 10:1191–1198. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Chen F, Bai G, Li Y, Feng Y and Wang L: A
positive feedback loop of long noncoding RNA CCAT2 and FOXM1
promotes hepatocellular carcinoma growth. Am J Cancer Res.
7:1423–1434. 2017.PubMed/NCBI
|
|
39
|
Liu J, Lu C, Xiao M, Jiang F, Qu L and Ni
R: Long non-coding RNA SNHG20 predicts a poor prognosis for HCC and
promotes cell invasion by regulating the epithelial-to-mesenchymal
transition. Biomed Pharmacother. 89:857–863. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Zhou M, Zhang XY and Yu X: Overexpression
of the long non-coding RNA SPRY4-IT1 promotes tumor cell
proliferation and invasion by activating EZH2 in hepatocellular
carcinoma. Biomed Pharmacother. 85:348–354. 2017. View Article : Google Scholar
|
|
41
|
Xiao JN, Yan TH, Yu RM, Gao Y, Zeng WL, Lu
SW, Que HX, Liu ZP and Jiang JH: Long non-coding RNA UCA1 regulates
the expression of Snail2 by miR-203 to promote hepatocellular
carcinoma progression. J Cancer Res Clin Oncol. 143:981–990. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Zhang Y, Li Z, Zhang Y, Zhong Q, Chen Q
and Zhang L: Molecular mechanism of HEIH and HULC in the
proliferation and invasion of hepatoma cells. Int J Clin Exp Med.
8:12956–12962. 2015.PubMed/NCBI
|
|
43
|
Cao SW, Huang JL, Chen J, Hu YW, Hu XM,
Ren TY, Zheng SH, Lin JD, Tang J, Zheng L and Wang Q: Long
non-coding RNA UBE2CP3 promotes tumor metastasis by inducing
epithelial-mesenchymal transition in hepatocellular carcinoma.
Oncotarget. 8:65370–65385. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Yan X, Zhang D, Wu W, Wu S, Qian J, Hao Y,
Yan F, Zhu P, Wu J, Huang G, et al: Mesenchymal stem cells promote
hepatocarcinogenesis via lncRNA-MUF interaction with ANXA2 and
miR-34a. Cancer Res. 77:6704–6716. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Lv J, Fan HX, Zhao XP, Lv P, Fan JY, Zhang
Y, Liu M and Tang H: Long non-coding RNA Unigene 56159 promotes
epithelial-mesenchymal transition by acting as a ceRNA of
miR-140-5p in hepatocellular carcinoma cells. Cancer Lett.
382:166–175. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Gou X, Zhao X and Wang Z: Long noncoding
RNA PVT1 promotes hepatocellular carcinoma progression through
regulating miR-214. Cancer Biomark. 20:511–519. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Ding G, Peng Z, Shang J, Kang Y, Ning H
and Mao C: LincRNA-p21 inhibits invasion and metastasis of
hepatocellular carcinoma through miR-9/E-cadherin cascade signaling
pathway molecular mechanism. Onco Targets Ther. 10:3241–3247. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Lan T, Chang L, Wu L and Yuan Y:
Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in
hepatocellular carcinoma. Mol Med Rep. 14:4606–4612. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Huang JF, Guo YJ, Zhao CX, Yuan SX, Wang
Y, Tang GN, Zhou WP and Sun SH: Hepatitis B virus X protein
(HBx)-related long noncoding RNA (lncRNA) down-regulated expression
by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by
targeting the intermediate filament protein vimentin. Hepatology.
57:1882–1892. 2013. View Article : Google Scholar
|
|
50
|
Wang TH, Lin YS, Chen Y, Yeh CT, Huang YL,
Hsieh TH, Shieh TM, Hsueh C and Chen TC: Long non-coding RNA AOC4P
suppresses hepatocellular carcinoma metastasis by enhancing
vimentin degradation and inhibiting epithelial-mesenchymal
transition. Oncotarget. 6:23342–23357. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Chang L, Li C, Lan T, Wu L, Yuan Y, Liu Q
and Liu Z: Decreased expression of long non-coding RNA GAS5
indicates a poor prognosis and promotes cell proliferation and
invasion in hepatocellular carcinoma by regulating vimentin. Mol
Med Rep. 13:1541–1550. 2016. View Article : Google Scholar :
|
|
52
|
Wang Y, Liu Z, Yao B, Li Q, Wang L, Wang
C, Dou C, Xu M, Liu Q and Tu K: Long non-coding RNA CASC2
suppresses epithelial-mesenchymal transition of hepatocellular
carcinoma cells through CASC2/miR-367/FBXW7 axis. Mol Cancer.
16:1232017. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Lamouille S, Xu J and Derynck R: Molecular
mechanisms of epithelial-mesenchymal transition. Nat Rev Mol Cell
Biol. 15:178–196. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
54
|
Li Q, Zhang C, Chen R, Xiong H, Qiu F, Liu
S, Zhang M, Wang F, Wang Y, Zhou X, et al: Disrupting
MALAT1/miR-200c sponge decreases invasion and migration in
endometrioid endometrial carcinoma. Cancer Lett. 383:28–40. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Lu W, Zhang H, Niu Y, Wu Y, Sun W, Li H,
Kong J, Ding K, Shen HM, Wu H, et al: Long non-coding RNA linc00673
regulated non-small cell lung cancer proliferation, migration,
invasion and epithelial mesenchymal transition by sponging
miR-150-5p. Mol Cancer. 16:1182017. View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Rodriguez-Mateo C, Torres B, Gutierrez G
and Pintor-Toro JA: Downregulation of Lnc-Spry1 mediates
TGF-beta-induced epithelial-mesenchymal transition by
transcriptional and post-transcriptional regulatory mechanisms.
Cell Death Differ. 24:785–797. 2017. View Article : Google Scholar
|
|
57
|
Li Z, Dong M, Fan D, Hou P, Li H, Liu L,
Lin C, Liu J, Su L, Wu L, et al: lncRNA ANCR down-regulation
promotes TGF-beta-induced EMT and metastasis in breast cancer.
Oncotarget. 8:67329–67343. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Wang Q, Yang L, Hu X, Jiang Y, Hu Y, Liu
Z, Liu J, Wen T, Ma Y, An G and Feng G: Upregulated NNT-AS1, a long
noncoding RNA, contributes to proliferation and migration of
colorectal cancer cells in vitro and in vivo. Oncotarget.
8:3441–3453. 2017. View Article : Google Scholar :
|
|
59
|
Pan H, Jiang T, Cheng N, Wang Q, Ren S, Li
X, Zhao C, Zhang L, Cai W and Zhou C: Long non-coding RNA BC087858
induces non-T790M mutation acquired resistance to EGFR-TKIs by
activating PI3K/AKT and MEK/ERK pathways and EMT in non-small-cell
lung cancer. Oncotarget. 7:49948–49960. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
60
|
Jia M, Jiang L, Wang YD, Huang JZ, Yu M
and Xue HZ: lincRNA-p21 inhibits invasion and metastasis of
hepatocellular carcinoma through Notch signaling-induced
epithelial-mesenchymal transition. Hepatol Res. 46:1137–1144. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Gao K, Ji Z, She K, Yang Q and Shao L:
Long non-coding RNA ZFAS1 is an unfavourable prognostic factor and
promotes glioma cell progression by activation of the Notch
signaling pathway. Biomed Pharmacother. 87:555–560. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Wu J, Zhang J, Shen B, Yin K, Xu J, Gao W
and Zhang L: Long noncoding RNA lncTCF7, induced by IL-6/STAT3
transactivation, promotes hepatocellular carcinoma aggressiveness
through epithelial-mesenchymal transition. J Exp Clin Cancer Res.
34:1162015. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Wang TH, Yu CC, Lin YS, Chen TC, Yeh CT,
Liang KH, Shieh TM, Chen CY and Hsueh C: Long noncoding RNA
CPS1-IT1 suppresses the metastasis of hepatocellular carcinoma by
regulating HIF-1alpha activity and inhibiting
epithelial-mesenchymal transition. Oncotarget. 7:43588–43603. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Hong Q, Li O, Zheng W, Xiao WZ, Zhang L,
Wu D, Cai GY, He JC and Chen XM: lncRNA HOTAIR regulates
HIF-1alpha/AXL signaling through inhibition of miR-217 in renal
cell carcinoma. Cell Death Dis. 8:e27722017. View Article : Google Scholar
|
|
65
|
Gupta RA, Shah N, Wang KC, Kim J, Horlings
HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, et al: Long
non-coding RNA HOTAIR reprograms chromatin state to promote cancer
metastasis. Nature. 464:1071–1076. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Geng YJ, Xie SL, Li Q, Ma J and Wang GY:
Large intervening non-coding RNA HOTAIR is associated with
hepatocellular carcinoma progression. J Int Med Res. 39:2119–2128.
2011. View Article : Google Scholar
|
|
67
|
Wang H, Huo XS, Yang XR, He J, Cheng L,
Wang N, Deng X, Jin H, Wang N, Wang C, et al: STAT3-mediated
upregulation of lncRNA HOXD-AS1 as a ceRNA facilitates liver cancer
metastasis by regulating SOX4. Molecular Cancer. 16:1362017.
View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Lu S, Zhou J, Sun Y, Li N, Miao M, Jiao B
and Chen H: The noncoding RNA HOXD-AS1 is a critical regulator of
the metastasis and apoptosis phenotype in human hepatocellular
carcinoma. Molecular Cancer. 16:1252017. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Malakar P, Shilo A, Mogilevsky A, Stein I,
Pikarsky E, Nevo Y, Benyamini H, Elgavish S, Zong X, Prasanth KV
and Karni R: Long noncoding RNA MALAT1 promotes hepatocellular
carcinoma development by SRSF1 upregulation and mTOR activation.
Cancer Research. 77:1155–1167. 2017. View Article : Google Scholar
|
|
70
|
Hou Z, Xu X, Fu X, Tao S, Zhou J, Liu S
and Tan D: HBx-related long non-coding RNA MALAT1 promotes cell
metastasis via up-regulating LTBP3 in hepatocellular carcinoma. Am
J Cancer Res. 7:845–856. 2017.PubMed/NCBI
|
|
71
|
Liu DL, Zhu Y, Pang JK, Weng X, Feng XR
and Guo YB: Knockdown of long non-coding RNA MALAT1 inhibits growth
and motility of human hepatoma cells via modulation of miR-195. J
Cell Biochem. 119:1368–1380. 2018. View Article : Google Scholar
|
|
72
|
Chen LS, Yao HB, Wang K and Liu XF: Long
non-coding RNA MALAT1 regulates ZEB1 expression by sponging
miR-143-3p and promotes hepatocellular carcinoma progression. J
Cell Biochem. 118:4836–4843. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
73
|
Li C, Miao R, Liu S, Wan Y, Zhang S, Deng
Y, Bi J, Qu K, Zhang J and Liu C: Down-regulation of miR-146b-5p by
long noncoding RNA MALAT1 in hepatocellular carcinoma promotes
cancer growth and metastasis. Oncotarget. 8:28683–28695. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Fan Y, Shen B, Tan M, Mu X, Qin Y, Zhang F
and Liu Y: TGF-β-induced upregulation of malat1 promotes bladder
cancer metastasis by associating with suz12. Clin Cancer Res.
20:1531–1541. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Sun HB, Lin DC, Cao Q, Pang B, Gae DD, Lee
VKM, Lim HJ, Doan N, Said JW, Gery S, et al: Identification of a
novel SYK/c-MYC/MALAT1 signaling pathway and its potential
therapeutic value in Ewing sarcoma. Clin Cancer Res. 23:4376–4387.
2017. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Yuan P, Cao WB, Zang QL, Li GX, Guo XF and
Fan JH: The HIF-2 alpha-MALAT1-miR-216b axis regulates multi-drug
resistance of hepatocellular carcinoma cells via modulating
autophagy. Biochem Bioph Res Commun. 478:1067–1073. 2016.
View Article : Google Scholar
|
|
77
|
Yang F, Zhang L, Huo XS, Yuan JH, Xu D,
Yuan SX, Zhu N, Zhou WP, Yang GS, Wang YZ, et al: Long noncoding
RNA high expression in hepatocellular carcinoma facilitates tumor
growth through enhancer of Zeste Homolog 2 in humans. Hepatology.
54:1679–1689. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Yuan SX, Yang F, Yang Y, Tao QF, Zhang J,
Huang G, Yang Y, Wang RY, Yang S, Huo XS, et al: Long noncoding RNA
associated with microvascular invasion in hepatocellular carcinoma
promotes angiogenesis and serves as a predictor for hepatocellular
carcinoma patients' poor recurrence-free survival after
hepatectomy. Hepatology. 56:2231–2241. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Li T, Xie J, Shen C, Cheng D, Shi Y, Wu Z,
Deng X, Chen H, Shen B, Peng C, et al: Upregulation of long
noncoding RNA ZEB1-AS1 promotes tumor metastasis and predicts poor
prognosis in hepatocellular carcinoma. Oncogene. 35:1575–1584.
2016. View Article : Google Scholar
|
|
80
|
Ren YL, Shang JH, Li JL, Liu W, Zhang Z,
Yuan J and Yang M: The long noncoding RNA PCAT-1 links the microRNA
miR-215 to oncogene CRKL-mediated signaling in hepatocellular
carcinoma. J Biol Chem. 292:17939–17949. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Yang F, Huo XS, Yuan SX, Zhang L, Zhou WP,
Wang F and Sun SH: Repression of the long noncoding RNA-LET by
histone deacetylase 3 contributes to hypoxia-mediated metastasis.
Mol Cell. 49:1083–1096. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Wang M, Guo C, Wang L, Luo G, Huang C, Li
Y, Liu D, Zeng F, Jiang G and Xiao X: Long noncoding RNA GAS5
promotes bladder cancer cells apoptosis through inhibiting EZH2
transcription. Cell Death Dis. 9:2382018. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Zhang Z, Zhu Z, Watabe K, Zhang X, Bai C,
Xu M, Wu F and Mo YY: Negative regulation of lncRNA GAS5 by miR-21.
Cell Death Differ. 20:1558–1568. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Zhao XH, Wang P, Liu J, Zheng J, Liu Y,
Chen J and Xue Y: Gas5 exerts tumor-suppressive functions in human
glioma cells by targeting miR-222. Mol Ther. 23:1899–1911. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Liu F, Yuan JH, Huang JF, Yang F, Wang TT,
Ma JZ, Zhang L, Zhou CC, Wang F, Yu J, et al: Long noncoding RNA
FTX inhibits hepatocellular carcinoma proliferation and metastasis
by binding MCM2 and miR-374a. Oncogene. 35:5422–5434. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Furlan G, Gutierrez Hernandez N, Huret C,
Galupa R, van Bemmel JG, Romito A, Heard E, Morey C and Rougeulle
C: The Ftx noncoding locus controls X chromosome inactivation
independently of its RNA products. Mol Cell. 70:462–472.e8. 2018.
View Article : Google Scholar : PubMed/NCBI
|
|
87
|
Zhuang LK, Yang YT, Ma X, Han B, Wang ZS,
Zhao QY, Wu LQ and Qu ZQ: MicroRNA-92b promotes hepatocellular
carcinoma progression by targeting Smad7 and is mediated by long
non-coding RNA XIST. Cell Death Dis. 7:e22032016. View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Chang SZ, Chen BH, Wang XY, Wu KQ and Sun
YQ: Long non-coding RNA XIST regulates PTEN expression by sponging
miR-181a and promotes hepatocellular carcinoma progression. BMC
Cancer. 17:2482017. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Kong Q, Zhang S, Liang C, Zhang Y, Kong Q,
Chen S, Qin J and Jin Y: lncRNA XIST functions as a molecular
sponge of miR-194-5p to regulate MAPK1 expression in hepatocellular
carcinoma cell. J Cell Biochem. 119:4458–4468. 2018. View Article : Google Scholar
|
|
90
|
Ma L, Zhou YJ, Luo XJ, Gao H, Deng XB and
Jiang YJ: Long non-coding RNA XIST promotes cell growth and
invasion through regulating miR-497/MACC1 axis in gastric cancer.
Oncotarget. 8:4125–4135. 2017. View Article : Google Scholar :
|
|
91
|
Chen DL, Chen LZ, Lu YX, Zhang DS, Zeng
ZL, Pan ZZ, Huang P, Wang FH, Li YH, Ju HQ and Xu RH: Long
noncoding RNA XIST expedites metastasis and modulates
epithelial-mesenchymal transition in colorectal cancer. Cell Death
Dis. 8:e30112017. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Wu XL, Dinglin XX, Wang X, Luo W, Shen Q,
Li Y, Gu L, Zhou Q, Zhu H, Li Y, et al: Long noncoding RNA XIST
promotes malignancies of esophageal squamous cell carcinoma via
regulation of miR-101/EZH2. Oncotarget. 8:76015–76028. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
93
|
Gramantieri L, Fornari F, Callegari E,
Sabbioni S, Lanza G, Croce CM, Bolondi L and Negrini M: MicroRNA
involvement in hepatocellular carcinoma. J Cell Mol Med.
12:2189–2204. 2008. View Article : Google Scholar
|
|
94
|
Schmitt M, Horbach A, Kubitz R, Frilling A
and Häussinger D: Disruption of hepatocellular tight junctions by
vascular endothelial growth factor (VEGF): A novel mechanism for
tumor invasion. J Hepatol. 41:274–283. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Choi SB, Han HJ, Kim WB, Song TJ and Choi
SY: VEGF overexpression predicts poor survival in hepatocellular
carcinoma. Open Med (Wars). 12:430–439. 2017. View Article : Google Scholar
|
|
96
|
Cao G, Li X, Qin C and Li J: Prognostic
value of VEGF in hepatocellular carcinoma patients treated with
Sorafenib: A meta-analysis. Med Sci Monit. 21:3144–3151. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
97
|
Fu WM, Lu YF, Hu BG, Liang WC, Zhu X, Yang
HD, Li G and Zhang JF: Long noncoding RNA Hotair mediated
angiogenesis in nasopharyngeal carcinoma by direct and indirect
signaling pathways. Oncotarget. 7:4712–4723. 2016. View Article : Google Scholar :
|
|
98
|
Ma X, Li Z, Li T, Zhu L, Li Z and Tian N:
Long non-coding RNA HOTAIR enhances angiogenesis by induction of
VEGFA expression in glioma cells and transmission to endothelial
cells via glioma cell derived-extracellular vesicles. Am J Transl
Res. 9:5012–5021. 2017.PubMed/NCBI
|
|
99
|
Su W, Xie W, Shang Q and Su B: The long
noncoding RNA MEG3 is downregulated and inversely associated with
vegf levels in osteoarthritis. Biomed Res Int. 2015:3568932015.
View Article : Google Scholar : PubMed/NCBI
|
|
100
|
Zhan R, Xu K, Pan J, Xu Q, Xu S and Shen
J: Long noncoding RNA MEG3 mediated angiogenesis after cerebral
infarction through regulating p53/NOX4 axis. Biochem Biophys Res
Commun. 490:700–706. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
101
|
Liu L, Chen X, Zhang Y, Hu Y, Shen X and
Zhu W: Long non-coding RNA TUG1 promotes endometrial cancer
development via inhibiting miR-299 and miR-34a-5p. Oncotarget.
8:31386–31394. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Jiang Q, Shan K, Qun-Wang X, Zhou RM, Yang
H, Liu C, Li YJ, Yao J, Li XM, Shen Y, et al: Long non-coding
RNA-MIAT promotes neurovascular remodeling in the eye and brain.
Oncotarget. 7:49688–49698. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
103
|
Li X, Song Y, Liu F, Liu D, Miao H, Ren J,
Xu J, Ding L, Hu Y, Wang Z, et al: Long non-coding RNA MALAT1
promotes proliferation, angiogenesis, and immunosuppressive
properties of mesenchymal stem cells by inducing VEGF and IDO. J
Cell Biochem. 118:2780–2791. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Zhu Y, Zhang X, Qi L, Cai Y, Yang P, Xuan
G and Jiang Y: HULC long noncoding RNA silencing suppresses
angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling
pathway in human gliomas. Oncotarget. 7:14429–14440. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
105
|
Xiao H, Tong R, Cheng S, Lv Z, Ding C, Du
C, Xie H, Zhou L, Wu J and Zheng S: BAG3 and HIF-1 alpha
coexpression detected by immunohistochemistry correlated with
prognosis in hepatocellular carcinoma after liver transplantation.
Biomed Res Int. 2014:5165182014. View Article : Google Scholar
|
|
106
|
Takahashi K, Yan IK, Haga H and Patel T:
Modulation of hypoxia-signaling pathways by extracellular linc-RoR.
J Cell Sci. 127:1585–1594. 2014.PubMed/NCBI
|
|
107
|
Zhuang J, Shen L, Yang L, Huang X, Lu Q,
Cui Y, Zheng X, Zhao X, Zhang D, Huang R, et al: TGFβ1 promotes
gemcitabine resistance through regulating the
lncRNA-LET/NF90/miR-145 signaling axis in bladder cancer.
Theranostcs. 7:3053–3067. 2017. View Article : Google Scholar
|
|
108
|
Zhu Z, Gao X, He Y, Zhao H, Yu Q, Jiang D,
Zhang P, Ma X, Huang H, Dong D, et al: An insertion/deletion
polymorphism within RERT-lncRNA modulates hepatocellular carcinoma
risk. Cancer Res. 72:6163–6172. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
109
|
Mineo M, Ricklefs F, Rooj AK, Lyons SM,
Ivanov P, Ansari KI, Nakano I, Chiocca EA, Godlewski J and Bronisz
A: The long non-coding RNA HIF1A-AS2 facilitates the maintenance of
mesenchymal glioblastoma stem-like cells in hypoxic Niches. Cell
Rep. 15:2500–2509. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
110
|
Wang J, Chen L, Li H, Yang J, Gong Z, Wang
B and Zhao X: Clopidogrel reduces apoptosis and promotes
proliferation of human vascular endothelial cells induced by
palmitic acid via suppression of the long non-coding RNA HIF1A-AS1
in vitro. Mol Cell Biochem. 404:203–210. 2015. View Article : Google Scholar : PubMed/NCBI
|
