|
1
|
Fann DY, Lee SY, Manzanero S, Chunduri P,
Sobey CG and Arumugam TV: Pathogenesis of acute stroke and the role
of inflammasomes. Ageing Res Rev. 12:941–966. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Bai J and Lyden PD: Revisiting cerebral
postischemic reperfusion injury: New insights in understanding
reperfusion failure, hemorrhage, and edema. Int J Stroke.
10:143–152. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Graham SH and Chen J: Programmed cell
death in cerebral ischemia. J Cereb Blood Flow Metab. 21:99–109.
2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Chen J, Jin K, Chen M, Pei W, Kawaguchi K,
Greenberg DA and Simon RP: Early detection of DNA strand breaks in
the brain after transient focal ischemia: Implications for the role
of DNA damage in apoptosis and neuronal cell death. J Neurochem.
69:232–245. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Barber PA, Demchuk AM, Hirt L and Buchan
AM: Biochemistry of ischemic stroke. Adv Neurol. 92:151–164.
2003.PubMed/NCBI
|
|
6
|
Sun FY, Lin X, Mao LZ, Ge WH, Zhang LM,
Huang YL and Gu J: Neuroprotection by melatonin against ischemic
neuronal injury associated with modulation of DNA damage and repair
in the rat following a transient cerebral ischemia. J Pineal Res.
33:48–56. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Nagata S: Apoptotic DNA fragmentation. Exp
Cell Res. 256:12–18. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Liu J, Li J, Yang Y, Wang X, Zhang Z and
Zhang L: Neuronal apoptosis in cerebral ischemia/reperfusion area
following electrical stimulation of fastigial nucleus. Neural Regen
Res. 9:727–734. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Yin KJ and Sun FY: Effect of
dextromethorphan, a NMDA antagonist, on DNA repair in rat
photochemical thrombotic cerebral ischemia. Brain Res. 815:29–35.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Zhang Y, Zhang Y, Jin XF, Zhou XH, Dong
XH, Yu WT and Gao WJ: The role of astragaloside IV against cerebral
ischemia/reperfusion injury: Suppression of apoptosis via promotion
of P62-LC3-Autophagy. Molecules. 24:18382019. View Article : Google Scholar :
|
|
11
|
Yue Z, Jin S, Yang C, Levine AJ and Heintz
N: Beclin 1, an autophagy gene essential for early embryonic
development, is a haploinsufficient tumor suppressor. Proc Natl
Acad Sci USA. 100:15077–15082. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kang R, Zeh HJ, Lotze MT and Tang D: The
Beclin 1 network regulates autophagy and apoptosis. Cell Death
Differ. 18:571–580. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Zhao Y, Huang G, Chen S, Gou Y, Dong Z and
Zhang X: Homocysteine aggravates cortical neural cell injury
through neuronal autophagy overactivation following rat cerebral
ischemia-reperfusion. Int J Mol Sci. 17:11962016. View Article : Google Scholar :
|
|
14
|
Su J, Zhang T, Wang K, Zhu T and Li X:
Autophagy activation contributes to the neuroprotection of remote
ischemic perconditioning against focal cerebral ischemia in rats.
Neurochem Res. 39:2068–2077. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Xu F, Fang Y, Yan L, Xu L, Zhang S, Cao Y,
Xu L, Zhang X, Xie J, Jiang G, et al: Nuclear localization of
Beclin 1 promotes radiation-induced DNA damage repair independent
of autophagy. Sci Rep. 7:453852017. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Lee JH and Paull TT: Direct activation of
the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science.
304:93–96. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Guide for the Care and Use of Laboratory
Animals. 8th edition. Washington, DC: 2011
|
|
18
|
Longa EZ, Weinstein PR, Carlson S and
Cummins R: Reversible middle cerebral artery occlusion without
craniectomy in rats. Stroke. 20:84–91. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(-Delta Delta C(T)) method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
20
|
Damia G: Targeting DNA-PK in cancer. Mutat
Res. 821:1116922020. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Schmidley JW: Free radicals in central
nervous system ischemia. Stroke. 21:1086–1090. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Thiyagarajan M and Sharma SS:
Neuroprotective effect of curcumin in middle cerebral artery
occlusion induced focal cerebral ischemia in rats. Life Sci.
74:969–985. 2004. View Article : Google Scholar
|
|
23
|
Zhao G, Zhang W, Li L, Wu S and Du G:
Pinocembrin protects the brain against ischemia-reperfusion injury
and reverses the autophagy dysfunction in the penumbra area.
Molecules. 19:15786–15798. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang X, Yan H, Yuan Y, Gao J, Shen Z,
Cheng Y, Shen Y, Wang RR, Wang X, Hu WW, et al: Cerebral
ischemia-reperfusion-induced autophagy protects against neuronal
injury by mitochondrial clearance. Autophagy. 9:1321–1333. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Xing S, Zhang Y, Li J, Zhang J, Li Y, Dang
C, Li C, Fan Y, Yu J, Pei Z and Zeng J: Beclin 1 knockdown inhibits
autophagic activation and prevents the secondary neurodegenerative
damage in the ipsilateral thalamus following focal cerebral
infarction. Autophagy. 8:63–76. 2012. View Article : Google Scholar
|
|
26
|
Shi CX, Jin J, Wang XQ, Song T, Li GH, Li
KZ and Ma JH: Sevoflurane attenuates brain damage through
inhibiting autophagy and apoptosis in cerebral ischemia-reperfusion
rats. Mol Med Rep. 21:123–130. 2020.
|
|
27
|
Sun X, Wang D, Zhang T, Lu X, Duan F, Ju
L, Zhuang X and Jiang X: Eugenol attenuates cerebral
ischemia-reperfusion injury by enhancing autophagy via
AMPK-mTOR-P70S6K pathway. Front Pharmacol. 11:842020. View Article : Google Scholar :
|
|
28
|
Rohatgi RA, Janusis J, Leonard D, Bellvé
KD, Fogarty KE, Baehrecke EH, Corvera S and Shaw LM: Beclin 1
regulates growth factor receptor signaling in breast cancer.
Oncogene. 34:5352–5362. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Tian M, Chen Y, Tian D, Qiao X, Ma Z and
Li J: Beclin1 antagonizes LAPTM4B-mediated EGFR overactivation in
gastric cancer cells. Gene. 626:48–53. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Fremont S, Gerard A, Galloux M, Janvier K,
Karess RE and Berlioz-Torrent C: Beclin-1 is required for
chromosome congression and proper outer kinetochore assembly. EMBO
Rep. 14:364–372. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Sun K, Fan J and Han J: Ameliorating
effects of traditional Chinese medicine preparation, Chinese
materia medica and active compounds on ischemia/reperfusion-induced
cerebral microcirculatory disturbances and neuron damage. Acta
Pharm Sin B. 5:8–24. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Ji B, Cheng B, Pan Y, Wang C, Chen J and
Bai B: Neuroprotection of bradykinin/bradykinin B2 receptor system
in cerebral ischemia. Biomed Pharmacother. 94:1057–1063. 2017.
View Article : Google Scholar : PubMed/NCBI
|
