|
1
|
Pang H, Han B, Yu T and Zong Z: Effect of
apelin on the cardiac hemodynamics in hypertensive rats with heart
failure. Int J Mol Med. 34:756–764. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Mozaffarian D, Benjamin EJ, Go AS, Arnett
DK, Blaha MJ, Cushman M, de Ferranti S, Després JP, Fullerton HJ,
Howard VJ, et al: Heart disease and stroke statistics-2015 update:
A report from the American heart association. Circulation.
131:e29–e322. 2015.
|
|
3
|
Sinphitukkul K, Manotham K and Eiam-Ong S
and Eiam-Ong S: Aldosterone nongenomically induces angiotensin II
receptor dimerization in rat kidney: Role of mineralocorticoid
receptor and NADPH oxidase. Arch Med Sci. 15:1589–1598. 2019.
View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Gao G, Chen W, Yan M, Liu J, Luo H, Wang C
and Yang P: Rapamycin regulates the balance between cardiomyocyte
apoptosis and autophagy in chronic heart failure by inhibiting mTOR
signaling. Int J Mol Med. 45:195–209. 2020.
|
|
5
|
Kang PM and Izumo S: Apoptosis and heart
failure: A critical review of the literature. Circ Res.
86:1107–1113. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wan GX, Ji LH, Xia WB, Cheng L and Zhang
YG: Bioinformatics identification of potential candidate blood
indicators for doxorubicin-induced heart failure. Exp Ther Med.
16:2534–2544. 2018.PubMed/NCBI
|
|
7
|
Tsutsumi Y, Matsubara H, Ohkubo N, Mori Y,
Nozawa Y, Murasawa S, Kijima K, Maruyama K, Masaki H, Moriguchi Y,
et al: Angiotensin II type 2 receptor is upregulated in human heart
with interstitial fibrosis, and cardiac fibroblasts are the major
cell type for its expression. Circ Res. 83:1035–1046. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Jurado Acosta A, Rysä J, Szabo Z, Moilanen
AM, Serpi R and Ruskoaho H: Phosphorylation of GATA4 at serine 105
is required for left ventricular remodelling process in angiotensin
II-induced hypertension in rats. Basic Clin Pharmacol. 127:178–195.
2020. View Article : Google Scholar
|
|
9
|
Fukami K, Ueda S, Yamagishi S, Kato S,
Inagaki Y, Takeuchi M, Motomiya Y, Bucala R, Iida S, Tamaki K, et
al: AGEs activate mesangial TGF-beta-Smad signaling via an
angiotensin II type I receptor interaction. Kidney Int.
66:2137–2147. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Wang X, Meng H, Wang Q, Shao M, Lu W, Chen
X, Jiang Y, Li C, Wang Y and Tu P: Baoyuan decoction ameliorates
apoptosis via AT1-CARP signaling pathway in H9C2 cells and heart
failure post-acute myocardial infarction rats. J Ethnopharmacol.
252:1125362020. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Zhan Y, Abe I, Nakagawa M, Ishii Y, Kira
S, Miyoshi M, Oniki T, Kondo H, Teshima Y, Yufu K, et al: A
traditional herbal medicine rikkunshito prevents angiotensin
II-Induced atrial fibrosis and fibrillation. J Cardiol. 76:626–635.
2020. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Wang W, You RL, Qin WJ, Hai LN, Fang MJ,
Huang GH, Kang RX, Li MH, Qiao YF, Li JW and Li AP: Anti-tumor
activities of active ingredients in compound Kushen injection. Acta
Pharmacol Sin. 36:676–679. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Wang HY, Hu HY, Rong H and Zhao XW:
Effects of compound Kushen injection on pathology and angiogenesis
of tumor tissues. Oncol Lett. 17:2278–2282. 2019.PubMed/NCBI
|
|
14
|
Xu W, Lin H, Zhang Y, Chen X, Hua B, Hou
W, Qi X, Pei Y, Zhu X, Zhao Z and Yang L: Compound Kushen injection
suppresses human breast cancer stem-like cells by down-regulating
the canonical Wnt/β-catenin pathway. J Exp Clin Canc Res.
30:1032011. View Article : Google Scholar
|
|
15
|
Lai BY, Chu AJ, Yu BW, Jia LY, Fan YY, Liu
JP and Pei XH: Clinical effectiveness and safety of Chinese herbal
medicine compound Kushen injection as an add-on treatment for
breast cancer: A systematic review and meta-analysis. Evid Based
Complement Alternat Med. 2022:81184082022. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Zhao Z, Liao H and Ju Y: Effect of
compound Kushen injection on T-cell subgroups and natural killer
cells in patients with locally advanced non-small-cell lung cancer
treated with concomitant radiochemotherapy. J Tradit Chin Med.
36:14–18. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Zhang J, Qu Z, Yao H, Sun L, Harata-Lee Y,
Cui J, Aung TN, Liu X, You R, Wang W, et al: An effective drug
sensitizing agent increases gefitinib treatment by down regulating
PI3K/Akt/mTOR pathway and up regulating autophagy in non-small cell
lung cancer. Biomed Pharmacother. 118:1091692019. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wang R, Zhang Q, Peng X, Zhou C, Zhong YX,
Chen X, Qiu Y, Jin M, Gong M and Kong D: Stellettin B induces G1
arrest, apoptosis and autophagy in human non-small cell lung cancer
A549 cells via blocking PI3K/Akt/mTOR pathway. Sci Rep.
6:270712016. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Liu MH, Zhang Y, He J, Tan TP, Wu SJ, Guo
DM, He H, Peng J, Tang ZH and Jiang ZS: Hydrogen sulfide protects
H9c2 cardiac cells against doxorubicin-induced cytotoxicity through
the PI3K/Akt/FoxO3a pathway. Int J Mol Med. 37:1661–1668. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ravingerová T, Matejíková J, Neckář J,
Andelová E and Kolář F: Differential role of PI3K/Akt pathway in
the infarct size limitation and antiarrhythmic protection in the
rat heart. Mol Cell Biochem. 297:111–120. 2007. View Article : Google Scholar
|
|
21
|
Huang J and Xu H: Matrine: Bioactivities
and structural modifications. Curr Top Med Chem. 16:3365–3378.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Xiao TT, Wang YY, Zhang Y, Bai CH and Shen
XC: Similar to spironolactone, oxymatrine is protective in
aldosterone-induced cardiomyocyte injury via inhibition of calpain
and apoptosis-inducing factor signaling. PLoS One. 9:e888562014.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Zhou YH, Shan H, Qiao G, Sui X, Lu Y and
Yang B: Inotropic effects and mechanisms of matrine, a main
alkaloid from Sophora flavescens AIT. Biol Pharm Bull.
31:2057–2062. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhang S, Guo S, Gao XB, Liu A, Jiang W,
Chen X, Yang P, Liu LN, Shi L and Zhang Y: Matrine attenuates
high-fat diet-induced in vivo and ox-LDL-induced in vitro vascular
injury by regulating the PKCα/eNOS and PI3K/Akt/eNOS pathways. J
Cell Mol Med. 23:2731–2743. 2019. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Li Y, Wang B, Zhou C and Bi Y: Matrine
induces apoptosis in angiotensin II-stimulated hyperplasia of
cardiac fibroblasts: Effects on Bcl-2/Bax expression and caspase-3
activation. Basic Clin Pharmacol Toxicol. 101:1–8. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Zhang Z, Qin X, Wang Z, Li Y, Chen F, Chen
R, Li C, Zhang W and Zhang M: Oxymatrine pretreatment protects H9c2
cardiomyocytes from hypoxia/reoxygenation injury by modulating the
PI3K/Akt pathway. Exp Ther Med. 21:5562021. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
National Research Council of The National
Academies: Guide for the care and use of laboratory animals. Eighth
edition. The National Academies Press; Washington, DC: 2011
|
|
28
|
Liu D, Zhan Y, Ono K, Yin Y, Wang L, Wei
M, Ji L, Liu M, Liu G, Zhou X and Zheng M: Pharmacological
activation of estrogenic receptor G protein-coupled receptor 30
attenuates angiotensin II-induced atrial fibrosis in ovariectomized
mice by modulating TGF-β1/smad pathway. Mol Biol Rep. 49:6341–6355.
2022. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Zhao Z, Fan H, Higgins T, Qi J, Haines D,
Trivett A, Oppenheim JJ, Wei H, Li J, Lin H and Howard OM: Fufang
Kushen injection inhibits sarcoma growth and tumor-induced
hyperalgesia via TRPV1 signaling pathways. Cancer Lett.
355:232–241. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Qu Z, Cui J, Harata-Lee Y, Aung TN, Feng
Q, Raison JM, Kortschak RD and Adelson DL: Identification of
candidate anti-cancer molecular mechanisms of compound Kushen
injection using functional genomics. Oncotarget. 7:660032016.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Chen S, Liu J, Liu X, Fu Y, Zhang M, Lin
Q, Zhu J, Mai L, Shan Z, Yu X, et al: Panax notoginseng saponins
inhibit ischemia-induced apoptosis by activating PI3K/Akt pathway
in cardiomyocytes. J Ethnopharmacol. 137:263–270. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Omland T, de Lemos JA, Sabatine MS,
Christophi CA, Rice MM, Jablonski KA, Tjora S, Domanski MJ, Gersh
BJ, Rouleau JL, et al: A sensitive cardiac troponin T assay in
stable coronary artery disease. N Engl J Med. 361:2538–2547. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Vergaro G, Gentile F, Meems LMG, Aimo A,
Januzzi JL Jr, Richards AM, Lam CSP, Latini R, Staszewsky L, Anand
IS, et al: NT-proBNP for risk prediction in heart failure:
Identification of optimal cutoffs across body mass index
categories. JACC Heart Fail. 9:653–663. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Tham YK, Bernardo BC, Ooi JYY, Weeks KL
and McMullen JR: Pathophysiology of cardiac hypertrophy and heart
failure: Signaling pathways and novel therapeutic targets. Arch
Toxicol. 89:1401–1438. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Goldenthal MJ: Mitochondrial involvement
in myocyte death and heart failure. Heart Fail Rev. 21:137–155.
2016. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Yao L, Chen H, Wu Q and Xie K:
Hydrogen-rich saline alleviates inflammation and apoptosis in
myocardial I/R injury via PINK-mediated autophagy. Int J Mol Med.
44:1048–1062. 2019.PubMed/NCBI
|
|
37
|
Sarbassov DD, Guertin DA, Ali SM and
Sabatini DM: Phosphorylation and regulation of Akt/PKB by the
rictor-mTOR complex. Science. 307:1098–1101. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Zhou Z, Zhang Y, Lin L and Zhou J:
Apigenin suppresses the apoptosis of H9C2 rat cardiomyocytes
subjected to myocardial ischemia-reperfusion injury via
upregulation of the PI3K/Akt pathway. Mol Med Rep. 18:1560–1570.
2018.PubMed/NCBI
|
|
39
|
Siddiqui WA, Ahad A and Ahsan H: The
mystery of BCL2 family: Bcl-2 proteins and apoptosis: An update.
Arch Toxicol. 89:289–317. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Er E, Oliver L, Cartron PF, Juin P, Manon
S and Vallette FM: Mitochondria as the target of the pro-apoptotic
protein Bax. Biochim Biophys Acta. 1757:1301–1311. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Riedl SJ and Salvesen GS: The apoptosome:
Signalling platform of cell death. Nat Rev Mol Cell Bio. 8:405–413.
2007. View Article : Google Scholar
|
|
42
|
Jeong SY, Han MH, Jin CY, Kim GY, Choi BT,
Nam TJ, Kim SK and Choi YH: Apoptosis induction of human leukemia
cells by Streptomyces sp. SY-103 metabolites through activation of
caspase-3 and inactivation of Akt. Int J Mol Med. 25:31–40.
2010.
|
|
43
|
Qin J, Tao D, Duan R, Leng Y, Shen M, Zhou
H, Feng Y, Gao C, Yu Y, Li QQ, et al: Cytokinetic analysis of cell
cycle and sub-phases in MOLT-4 cells by cyclin E + A/DNA
multiparameter flow cytometry. Oncol Rep. 9:1041–1045.
2002.PubMed/NCBI
|
|
44
|
Meikrantz W and Schlegel R: Apoptosis and
the cell cycle. J Cell Biochem. 58:160–174. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Zhao Y, Chen Y, Wang J and Liu L: Effects
of ATP-binding cassette transporter G2 in extracellular vesicles on
drug resistance of laryngeal cancer cells in in vivo and in vitro.
Oncol Lett. 21:3642021. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Lukas J, Bartkova J, Rohde M, Strauss M
and Bartek J: Cyclin D1 is dispensable for G1 control in
retinoblastoma gene-deficient cells independently of cdk4 activity.
Mol Cell Biol. 15:2600–2611. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Liu Y, Lian Q, Li X, Zhou X, Gao H and Cui
T: Matrine alleviates heart failure in rats by resisting
inflammatory response and oxidative stress and reducing cardiac
myocyte apoptosis. Lat Am J Pharm. 38:2170–2176. 2019.
|
|
48
|
Zhang Y, Cui L, Guan G, Wang J, Qiu C,
Yang T, Guo Y and Liu Z: Matrine suppresses cardiac fibrosis by
inhibiting the TGF-β/Smad pathway in experimental diabetic
cardiomyopathy. Mol Med Rep. 17:1775–1781. 2018.
|
|
49
|
Hu ST, Tang Y, Shen YF, Ao HH, Bai J, Wang
YL and Yang YJ: Protective effect of oxymatrine on chronic rat
heart failure. J Physiol Sci. 61:363–372. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Li C, Gao Y, Tian J, Shen J, Xing Y and
Liu Z: Sophocarpine administration preserves myocardial function
from ischemia-reperfusion in rats via NF-κB inactivation. J
Ethnopharmacol. 135:620–625. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Li J, Li L, Chu H, Sun X and Ge Z: Oral
sophocarpine protects rat heart against pressure overload-induced
cardiac fibrosis. Pharm Biol. 52:1045–1051. 2014. View Article : Google Scholar : PubMed/NCBI
|
