|
1
|
Doorbar J, Quint W, Banks L, Bravo IG,
Stoler M, Broker TR and Stanley MA: The biology and life-cycle of
human papillomaviruses. Vaccine. 30(Suppl 5): F55–F70. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Woodworth CD: HPV innate immunity. Front
Biosci. 7:d2058–d2071. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Chen L, Hu H, Pan Y, Lu Y, Zhao M, Zhao Y,
Wang L, Liu K and Yu Z: The role of HPV11 E7 in modulating
STING-dependent interferon β response in recurrent respiratory
papillomatosis. J Virol. 98:e01925232024. View Article : Google Scholar
|
|
4
|
Doorbar J, Egawa N, Griffin H, Kranjec C
and Murakami I: Human papillomavirus molecular biology and disease
association. Rev Med Virol. 25(Suppl 1): S2–S23. 2015. View Article : Google Scholar
|
|
5
|
Crosbie EJ, Einstein MH, Franceschi S and
Kitchener HC: Human papillomavirus and cervical cancer. Lancet.
382:889–899. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
McBride AA: Oncogenic human
papillomaviruses. Philos Trans R Soc Lond B Biol Sci.
372:201602732017. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Duensing S and Münger K: The human
papillomavirus type 16 E6 and E7 oncoproteins independently induce
numerical and structural chromosome instability. Cancer Res.
62:7075–7082. 2002.PubMed/NCBI
|
|
8
|
Klingelhutz AJ and Roman A: Cellular
transformation by human papillomaviruses: lessons learned by
comparing high- and low-risk viruses. Virology. 424:77–98. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Zhang B, Chen W and Roman A: The E7
proteins of low- and high-risk human papillomaviruses share the
ability to target the pRB family member p130 for degradation. Proc
Natl Acad Sci USA. 103:437–442. 2006. View Article : Google Scholar :
|
|
10
|
Münger K, Werness BA, Dyson N, Phelps WC,
Harlow E and Howley PM: Complex formation of human papillomavirus
E7 proteins with the retinoblastoma tumor suppressor gene product.
EMBO J. 8:4099–4105. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Dyson N, Howley PM, Münger K and Harlow E:
The human papilloma virus-16 E7 oncoprotein is able to bind to the
retinoblastoma gene product. Science. 243:934–937. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Boulet G, Horvath C, Vanden Broeck D,
Sahebali S and Bogers J: Human papillomavirus: E6 and E7 oncogenes.
Int J Biochem Cell Biol. 39:2006–2011. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Ryser MD, Rositch A and Gravitt PE:
Modeling of US human papillomavirus (HPV) seroprevalence by age and
sexual behavior indicates an increasing trend of HPV infection
following the sexual revolution. J Infect Dis. 216:604–611. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Forman D, de Martel C, Lacey CJ,
Soerjomataram I, Lortet-Tieulent J, Bruni L, Vignat J, Ferlay J,
Bray F, Plummer M and Franceschi S: Global Burden of Human
Papillomavirus and Related Diseases. Vaccine. 30(Suppl 5): F12–F23.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yang X, Li Y, Tang Y, Li Z, Wang S, Luo X,
He T, Yin A and Luo M: Cervical HPV infection in Guangzhou, China:
An epidemiological study of 198,111 women from 2015 to 2021. Emerg
Microbes Infect. 12:e21760092023. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Han S, Lin M, Liu M, Wu S, Guo P, Guo J,
Xie L, Qiu S, Xu A, Cai Y and Chen Y: Prevalence, trends, and
geographic distribution of human papillomavirus infection in
Chinese women: A summative analysis of 2,728,321 cases. BMC Med.
23:1582025. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Crow JM: HPV: The global burden. Nature.
488:S2–S3. 2012. View
Article : Google Scholar : PubMed/NCBI
|
|
18
|
Wang J, Elfström KM and Dillner J: Human
papilloma-virus-based cervical screening and long-term cervical
cancer risk: A randomised health-care policy trial in Sweden.
Lancet Public Health. 9:e886–e895. 2024. View Article : Google Scholar
|
|
19
|
Graham SV: The human papillomavirus
replication cycle, and its links to cancer progression: A
comprehensive review. Clin Sci (Lond). 131:2201–2221. 2017.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
zur Hausen H: Papillomaviruses in the
causation of human cancers-a brief historical account. Virology.
384:260–265. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
del Pino M, Bleeker MC, Quint WG, Snijders
PJ, Meijer CJ and Steenbergen RD: Comprehensive analysis of human
papillomavirus prevalence and the potential role of low-risk types
in verrucous carcinoma. Mod Pathol. 25:1354–1363. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Jamshidi M, Shekari M, Nejatizadeh A,
Malekzadeh K, Baghershiroodi M, Davudian P, Dehghan F and Jamshidi
F: The impact of human papillomavirus (HPV) types 6, 11 in women
with genital warts. Arch Gynecol Obstet. 286:1261–1267. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Friedman JR and Nunnari J: Mitochondrial
form and function. Nature. 505:335–343. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Gkikas I, Palikaras K and Tavernarakis N:
The role of mitophagy in innate immunity. Front Immunol.
9:12832018. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Mehta MM, Weinberg SE and Chandel NS:
Mitochondrial control of immunity: Beyond ATP. Nat Rev Immunol.
17:608–620. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Mills EL, Kelly B and O'Neill LAJ:
Mitochondria are the power-houses of immunity. Nat Immunol.
18:488–498. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Onishi M, Yamano K, Sato M, Matsuda N and
Okamoto K: Molecular mechanisms and physiological functions of
mitophagy. EMBO J. 40:e1047052021. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zhang L, Qin Y and Chen M: Viral
strategies for triggering and manipulating mitophagy. Autophagy.
14:1665–1673. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Moehlman AT and Youle RJ: Mitochondrial
quality control and restraining innate immunity. Annu Rev Cell Dev
Biol. 36:265–289. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Kim MJ, Bae SH, Ryu JC, Kwon Y, Oh JH,
Kwon J, Moon JS, Kim K, Miyawaki A, Lee MG, et al: SESN2/sestrin2
suppresses sepsis by inducing mitophagy and inhibiting NLRP3
activation in macrophages. Autophagy. 12:1272–1291. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Qi N, Shi Y, Zhang R, Zhu W, Yuan B, Li X,
Wang C, Zhang X and Hou F: Multiple truncated isoforms of MAVS
prevent its spontaneous aggregation in antiviral innate immune
signalling. Nat Commun. 8:156762017. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Jena KK, Mehto S, Nath P, Chauhan NR, Sahu
R, Dhar K, Das SK, Kolapalli SP, Murmu KC, Jain A, et al:
Autoimmunity gene IRGM suppresses cGAS-STING and RIG-I-MAVS
signaling to control interferon response. EMBO Rep. 21:e500512020.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Bu L, Wang H, Hou P, Guo S, He M, Xiao J,
Li P, Zhong Y, Jia P, Cao Y, et al: The Ubiquitin E3 ligase parkin
inhibits innate antiviral immunity through K48-linked
polyubiquitination of RIG-I and MDA5. Front Immunol. 11:19262020.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sliter DA, Martinez J, Hao L, Chen X, Sun
N, Fischer TD, Burman JL, Li Y, Zhang Z, Narendra DP, et al: Parkin
and PINK1 mitigate STING-induced inflammation. Nature. 561:258–262.
2018. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Kim SJ, Khan M, Quan J, Till A, Subramani
S and Siddiqui A: Hepatitis B virus disrupts mitochondrial
dynamics: Induces fission and mitophagy to attenuate apoptosis.
PLoS Pathog. 9:e10037222013. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Adriaenssens E, Nguyen TN, Sawa-Makarska
J, Khuu G, Schuschnig M, Shoebridge S, Skulsuppaisarn M, Watts EM,
Csalyi KD, Padman BS, et al: Control of mitophagy initiation and
progression by the TBK1 adaptors NAP1 and SINTBAD. Nat Struct Mol
Biol. 31:1717–1731. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Zhao X, Wang Z, Wang L, Jiang T, Dong D
and Sun M: The PINK1/Parkin signaling pathway-mediated mitophagy: A
forgotten protagonist in myocardial ischemia/reperfusion injury.
Pharmacol Res. 209:1074662024. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
O'Sullivan TE, Johnson LR, Kang HH and Sun
JC: BNIP3- and BNIP3L-mediated mitophagy promotes the generation of
natural killer cell memory. Immunity. 43:331–342. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Zhang B, Xu S, Liu M, Wei Y, Wang Q, Shen
W, Lei CQ and Zhu Q: The nucleoprotein of influenza A virus
inhibits the innate immune response by inducing mitophagy.
Autophagy. 19:1916–1933. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Sun Z, Ma Z, Cao W, Jiang C, Guo L, Liu K,
Gao Y, Bai J, Pi J, Jiang P and Liu X: Calcium-mediated
mitochondrial fission and mitophagy drive glycolysis to facilitate
arterivirus proliferation. PLoS Pathog. 21:e10128722025. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Khan M, Syed GH, Kim SJ and Siddiqui A:
Hepatitis B virus-induced parkin-dependent recruitment of linear
ubiquitin assembly complex (LUBAC) to mitochondria and attenuation
of innate immunity. PLoS Pathog. 12:e10056932016. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Vo MT, Smith BJ, Nicholas J and Choi YB:
Activation of NIX-mediated mitophagy by an interferon regulatory
factor homologue of human herpesvirus. Nat Commun. 10:32032019.
View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Kim SJ, Syed GH and Siddiqui A: Hepatitis
C virus induces the mitochondrial translocation of Parkin and
subsequent mitophagy. PLoS Pathog. 9:e10032852013. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Ojeda DS, Grasso D, Urquiza J, Till A,
Vaccaro MI and Quarleri J: Cell death is counteracted by mitophagy
in HIV-productively infected astrocytes but is promoted by
inflammasome activation among non-productively infected cells.
Front Immunol. 9:26332018. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Perkins DN, Pappin DJ, Creasy DM and
Cottrell JS: Probability-based protein identification by searching
sequence databases using mass spectrometry data. Electrophoresis.
20:3551–3567. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Thomas RJ, Oleinik N, Panneer Selvam S,
Vaena SG, Dany M, Nganga RN, Depalma R, Baron KD, Kim J, Szulc ZM
and Ogretmen B: HPV/E7 induces chemotherapy-mediated tumor
suppression by ceramide-dependent mitophagy. EMBO Mol Med.
9:1030–1051. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Russell WMS and Burch RL: The Principles
of Humane Experimental Technique. Methuen & Co., Ltd.; London:
1959
|
|
48
|
American Veterinary Medical Association
(AVMA): AVMA Guidelines for the euthanasia of animals: 2013
Edition. AVMA; Schaumburg, IL: 2013
|
|
49
|
Chen S, Zhou Y, Chen Y and Gu J: fastp: An
ultra-fast all-in-one FASTQ preprocessor. Bioinformatics.
34:i884–i890. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Kim D, Langmead B and Salzberg SL: HISAT:
A fast spliced aligner with low memory requirements. Nat Methods.
12:357–360. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Pertea M, Pertea GM, Antonescu CM, Chang
TC, Mendell JT and Salzberg SL: StringTie enables improved
reconstruction of a transcriptome from RNA-seq reads. Nat
Biotechnol. 33:290–295. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Love MI, Huber W and Anders S: Moderated
estimation of fold change and dispersion for RNA-seq data with
DESeq2. Genome Biol. 15:5502014. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Wang L, Feng Z, Wang X, Wang X and Zhang
X: DEGseq: An R package for identifying differentially expressed
genes from RNA-seq data. Bioinformatics. 26:136–138. 2010.
View Article : Google Scholar
|
|
54
|
Klopfenstein DV, Liangsheng Z, Pedersen
BS, Ramírez F, Warwick Vesztrocy A, Naldi A, Mungall CJ, Yunes JM,
Botvinnik O, Weigel M, et al: GOATOOLS: A python library for Gene
ontology analyses. Sci Rep. 8:108722018. View Article : Google Scholar : PubMed/NCBI
|
|
55
|
Kanehisa M, Furumichi M, Sato Y, Matsuura
Y and Ishiguro-Watanabe M: KEGG: Biological systems database as a
model of the real world. Nucleic Acids Res. 53(D1): D672–D677.
2025. View Article : Google Scholar :
|
|
56
|
Langfelder P and Horvath S: WGCNA: An R
package for weighted correlation network analysis. BMC
Bioinformatics. 9:5592008. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
Shen S, Park JW, Lu ZX, Lin L, Henry MD,
Wu YN, Zhou Q and Xing Y: rMATS: Robust and flexible detection of
differential alternative splicing from replicate RNA-Seq data. Proc
Natl Acad Sci USA. 111:E5593–E5601. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Jiang X, Arrey T, Damoc E, Scigelova M,
Horn D, Viner R and Huhmer AFR: TMT Workflow on the Q Exactive
Series-Instrument Parameter Optimization and Data Analysis in
Proteome Discoverer 2.1 Software. Thermo Fisher Scientific Inc.;
2016
|
|
59
|
Apweiler R, Bairoch A, Wu CH, Barker WC,
Boeckmann B, Ferro S, Gasteiger E, Huang H, Lopez R, Magrane M, et
al: UniProt: The universal protein knowledgebase. Nucleic Acids
Res. 32(Database issue): D115–D119. 2004. View Article : Google Scholar :
|
|
60
|
De Luca A, De Falco M, Severino A,
Campioni M, Santini D, Baldi F, Paggi MG and Baldi A: Distribution
of the serine protease HtrA1 in normal human tissues. J Histochem
Cytochem. 51:1279–1284. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Shi H, Yuan M, Cai J, Lan L, Wang Y, Wang
W, Zhou J, Wang B, Yu W, Dong Z, et al: HTRA1-driven detachment of
type I collagen from endoplasmic reticulum contributes to
myocardial fibrosis in dilated cardiomyopathy. J Transl Med.
22:2972024. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Ding Y, Jiang S, Chen X, Chen L, Zhang X
and Cheng H: Expression and polyclonal antibody preparation of
HPV-11E7 protein. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 30:618–622.
2014.In Chinese. PubMed/NCBI
|
|
63
|
Cao L, Cheng H, Wang H, Zhou Q, Tang Z,
Jiang S, Ding Y and Chen X: Research on the Detection of Condyloma
Acuminatum Lesions Using Self-prepared Polyclonal Antibodies
against HPV6b and 11 E7 Proteins. Chin J Dermatol. 11:774–777.
2015.In Chinese.
|
|
64
|
Hua C, Zheng Q, Zhu J, Chen S, Song Y, van
der Veen S and Cheng H: Human papillomavirus type 16 early protein
E7 activates autophagy through inhibition of dual-specificity
phosphatase 5. Oxid Med Cell Longev. 2022:18630982022. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Song Y, Wu X, Xu Y, Zhu J, Li J, Zou Z,
Chen L, Zhang B, Hua C, Rui H, et al: HPV E7 inhibits cell
pyroptosis by promoting TRIM21-mediated degradation and
ubiquitination of the IFI16 inflammasome. Int J Biol Sci.
16:2924–2937. 2020. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Livak KJ and Schmittgen TD: Analysis of
relative gene expression data using real-time quantitative PCR and
the 2(−Delta Delta C(T)) Method. Methods. 25:402–408. 2001.
View Article : Google Scholar
|
|
67
|
Qin X, Chen H, Zhu X, Xu X and Gao J:
Identification of Rab7 as an autophagy marker: Potential
therapeutic approaches and the effect of Qi Teng Xiao Zhuo granule
in chronic glomerulonephritis. Pharm Biol. 61:1120–1134. 2023.
View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S,
Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu
YP, Acevedo-Arozena A, et al: Guidelines for the use and
interpretation of assays for monitoring autophagy (4th edition).
Autophagy. 17:1–382. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Barbaro V, Testa A, Di Iorio E, Mavilio F,
Pellegrini G and De Luca M: C/EBPδ regulates cell cycle and
self-renewal of human limbal stem cells. J Cell Biol.
177:1037–1049. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
70
|
Rahman MS, Kang I, Lee Y, Habib MA, Choi
BJ, Kang JS, Park DS and Kim YS: Bifidobacterium longum subsp.
infantis YB0411 inhibits adipogenesis in 3T3-L1 pre-adipocytes and
reduces high-fat-diet-induced obesity in mice. J Agric Food Chem.
69:6032–6042. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Malpartida AB, Williamson M, Narendra DP,
Wade-Martins R and Ryan BJ: Mitochondrial dysfunction and mitophagy
in Parkinson's disease: From mechanism to therapy. Trends Biochem
Sci. 46:329–343. 2021. View Article : Google Scholar
|
|
72
|
Song SN, Li HJ, Liang JL, Ren QQ, Li CX
and Xu SY: Lentivirus-mediated missense mutation in HtrA1 leads to
activation of the TGF-β/Smads pathway and increased apoptosis of
mouse brain microvascular endothelial cells via the oxidative
stress pathway. J Integr Neurosci. 23:2012024. View Article : Google Scholar
|
|
73
|
Lee J, Huh S, Park K, Kang N, Yu HS, Park
HG, Kim YS, Kang UG, Won S and Kim SH: Behavioral and
transcriptional effects of repeated electroconvulsive seizures in
the neonatal MK-801-treated rat model of schizophrenia.
Psychopharmacology (Berl). 241:817–832. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Barnard SJ, Haunschild J, Heiser L,
Dieterlen MT, Klaeske K, Borger MA and Etz CD: Apoptotic cell death
in bicuspid-aortic-valve-associated aortopathy. Int J Mol Sci.
24:74292023. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Gutiérrez-Muñoz C, Blázquez-Serra R, San
Sebastian-Jaraba I, Sanz-Andrea S, Fernández-Gómez MJ, Nuñez-Moreno
G, Mínguez P, Escolá-Gil JC, Nogales P, Ollivier V, et al: Annexin
A8 deficiency delays atherosclerosis progression. Clin Transl Med.
15:e701762025. View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Zhou GZ, Sun YH, Shi YY, Zhang Q, Zhang L,
Cui LQ and Sun GC: ANXA8 regulates proliferation of human non-small
lung cancer cells A549 via EGFR-AKT-mTOR signaling pathway. Mol
Biol (Mosk). 55:870–880. 2021. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Wei Y, Li Q, He K, Liao G, Cheng L, Li M
and He Z: Mechanism of cigarette smoke in promoting small airway
remodeling in mice via STAT 3 / PINK 1-Parkin / EMT. Free Radic
Biol Med. 224:447–456. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
78
|
Yan J, Chen X, Choksi S and Liu ZG: TGFB
signaling induces mitophagy via PLSCR3-mediated cardiolipin
externalization in conjunction with a BNIP3L/NIX-, BNIP3-, and
FUNDC1-dependent mechanism. Autophagy. 21:1791–1801. 2025.
View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Adriaenssens E, Schaar S, Cook ASI, Stuke
JFM, Sawa-Makarska J, Nguyen TN, Ren X, Schuschnig M, Romanov J,
Khuu G, et al: Reconstitution of BNIP3/NIX-mitophagy initiation
reveals hierarchical flexibility of the autophagy machinery. Nat
Cell Biol. 27:1272–1287. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
80
|
Yan T, Li H, Yan J, Ma S and Tan J:
Age-related mitophagy regulates orthodontic tooth movement by
affecting PDLSCs mitochondrial function and RANKL/OPG. FASEB J.
38:e238652024. View Article : Google Scholar : PubMed/NCBI
|
|
81
|
Stuqui B, Conceição AL, Termini L, Sichero
L, Villa LL, Rahal P and Calmon MF: The differential role of HTRA1
in HPV-positive and HPV-negative cervical cell line proliferation.
BMC Cancer. 16:8402016. View Article : Google Scholar : PubMed/NCBI
|
|
82
|
Chien J, Ota T, Aletti G, Shridhar R,
Boccellino M, Quagliuolo L, Baldi A and Shridhar V: Serine protease
HtrA1 associates with microtubules and inhibits cell migration. Mol
Cell Biol. 29:4177–4187. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
83
|
Antonsson A, Payne E, Hengst K and
McMillan N: The human papillomavirus type 16 E7 protein binds human
interferon regulatory factor-9 via a novel PEST domain required for
transformation. J Interferon Cytokine Res. 26:455–461. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
84
|
Martínez-Campos C, Burguete-García AI and
Madrid-Marina V: Role of TLR9 in oncogenic virus-produced cancer.
Viral Immunol. 30:98–105. 2017. View Article : Google Scholar : PubMed/NCBI
|
|
85
|
Pacini L, Savini C, Ghittoni R, Saidj D,
Lamartine J, Hasan UA, Accardi R and Tommasino M: Downregulation of
toll-like receptor 9 expression by beta human papillomavirus 38 and
implications for cell cycle control. J Virol. 89:11396–11405. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
86
|
Lo Cigno I, Calati F, Borgogna C, Zevini
A, Albertini S, Martuscelli L, De Andrea M, Hiscott J, Landolfo S
and Gariglio M: Human papillomavirus E7 oncoprotein subverts host
innate immunity via SUV39H1-mediated epigenetic silencing of immune
sensor genes. J Virol. 94:e01812–19. 2020. View Article : Google Scholar :
|
|
87
|
Park JS, Kim EK, Kwon HJ, Hwang ES,
Namkoong SE and Um SJ: Inactivation of interferon regulatory
factor-1 tumor suppressor protein by HPV E7 oncoprotein.
Implication for the E7-mediated immune evasion mechanism in
cervical carcinogenesis. J Biol Chem. 275:6764–6769. 2000.
View Article : Google Scholar : PubMed/NCBI
|
|
88
|
Um SJ, Rhyu JW, Kim EJ, Jeon KC, Hwang ES
and Park JS: Abrogation of IRF-1 response by high-risk HPV E7
protein in vivo. Cancer Lett. 179:205–212. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
89
|
Ray J, Baidya J, Paul DP, Majumdar G,
Debbarma S, Sarkar A, Chakma M, Barman MP, Pattnaik M, Debnath A
and Nath S: Molecular epidemiology and genotype distribution of
genital high-risk human papillomavirus among women in North-East
India. Egypt J Med Hum Genet. 26:1142025. View Article : Google Scholar
|
|
90
|
Hongo T, Yamamoto H, Tanabe M, Yasumatsu
R, Kuga R, Miyazaki Y, Jiromaru R, Hashimoto K, Tateishi Y, Sonoda
KH, et al: High-risk HPV-related squamous cell carcinoma in the
conjunctiva and lacrimal sac: Clinicopathologic characteristics and
diagnostic utility of p16 and Rb immunohistochemistry. Am J Surg
Pathol. 46:977–987. 2022. View Article : Google Scholar : PubMed/NCBI
|
|
91
|
Wolf J, Kist LF, Pereira SB, Quessada MA,
Petek H, Pille A, Maccari JG, Mutlaq MP and Nasi LA: Human
papillomavirus infection: Epidemiology, biology, host interactions,
cancer development, prevention, and therapeutics. Rev Med Virol.
34:e25372024. View Article : Google Scholar : PubMed/NCBI
|
|
92
|
Shah KD, Chamseddine I, Yuan X, Tian S,
Qiu R, Zhou J, Dhabaan A, Al-Hallaq H, Yu DS, Paganetti H and Yang
X: Clinically interpretable survival risk stratification in head
and neck cancer using bayesian networks and markov blankets. Int J
Radiat Oncol Biol Phys:. S0360-3016 (25) 06336-9. Oct
11–2025.Epubahead of print. View Article : Google Scholar
|
|
93
|
Niu Y, Nie Q, Dong L, Zhang J, Liu SF,
Song W, Wang X, Wu G and Song D: Hydrogen attenuates allergic
inflammation by reversing energy metabolic pathway switch. Sci Rep.
10:19622020. View Article : Google Scholar : PubMed/NCBI
|
|
94
|
Savagner F, Farge T, Karim Z and Aloulou
M: Iron and energy metabolic interactions in Treg-mediated immune
regulation. Front Immunol. 16:15540282025. View Article : Google Scholar : PubMed/NCBI
|
|
95
|
Gupta S, Cassel SL, Sutterwala FS and
Dagvadorj J: Regulation of the NLRP3 inflammasome by autophagy and
mitophagy. Immunol Rev. 329:e134102025. View Article : Google Scholar :
|
|
96
|
Tao G, Wang X, Wang J, Ye Y, Zhang M, Lang
Y and Ding S: Dihydro-resveratrol ameliorates NLRP3
inflammasome-mediated neuroinflammation via Bnip3-dependent
mitophagy in Alzheimer's disease. Br J Pharmacol. 182:1005–1024.
2025. View Article : Google Scholar
|
|
97
|
Zhao Y, Ding C, Zhu Z, Wang W, Wen W,
Favoreel HW and Li X: Pseudorabies virus infection triggers
mitophagy to dampen the interferon response and promote viral
replication. J Virol. 98:e01048242024. View Article : Google Scholar : PubMed/NCBI
|
|
98
|
Cheng J, Wang Y, Yin L, Liang W, Zhang J,
Ma C, Zhang Y, Liu B, Wang J, Zhao W, et al: The nonstructural
protein 1 of respiratory syncytial virus hijacks host mitophagy as
a novel mitophagy receptor to evade the type I IFN response in
HEp-2 cells. mBio. 14:e01480232023. View Article : Google Scholar : PubMed/NCBI
|
|
99
|
Weng W, He Z, Ma Z, Huang J, Han Y, Feng
Q, Qi W, Peng Y, Wang J, Gu J, et al: Tufm lactylation regulates
neuronal apoptosis by modulating mitophagy in traumatic brain
injury. Cell Death Differ. 32:530–545. 2025. View Article : Google Scholar
|
|
100
|
Gu B, Yu W, Huang Z, Bai J, Liu S, Ren B,
Wang P, Sun L, Wen J, Zheng Y, et al: MRG15 promotes cell apoptosis
through inhibition of mitophagy in hyperlipidemic acute
pancreatitis. Apoptosis. 30:149–166. 2025. View Article : Google Scholar
|
|
101
|
Lee J and Ou JJ: HCV-induced autophagy and
innate immunity. Front Immunol. 15:13051572024. View Article : Google Scholar : PubMed/NCBI
|
|
102
|
Song X, Wang Y, Zou W, Wang Z, Cao W,
Liang M, Li F, Zeng Q, Ren Z, Wang Y and Zheng K: Inhibition of
mitophagy via the EIF2S1-ATF4-PRKN pathway contributes to viral
encephalitis. J Adv Res. 73:199–217. 2025. View Article : Google Scholar :
|
|
103
|
Figarola-Centurión I, Escoto-Delgadillo M,
González-Enríquez GV, Gutiérrez-Sevilla JE, Vázquez-Valls E,
Cárdenas-Bedoya J and Torres-Mendoza BM: HIV-1 Tat induces
dysregulation of PGC1-Alpha and Sirtuin 3 expression in neurons:
The role of mitochondrial biogenesis in HIV-Associated
neurocognitive disorder (HAND). Int J Mol Sci. 24:175662023.
View Article : Google Scholar : PubMed/NCBI
|
|
104
|
Toyohara Y, Taguchi A, Ishii Y, Yoshimoto
D, Yamazaki M, Matsunaga H, Nakatani K, Hoshi D, Tsuchimochi S,
Kusakabe M, et al: Identification of target cells of human
papillomavirus 18 using squamocolumnar junction organoids. Cancer
Sci. 115:125–138. 2024. View Article : Google Scholar :
|
|
105
|
Chien J, Aletti G, Baldi A, Catalano V,
Muretto P, Keeney GL, Kalli KR, Staub J, Ehrmann M, Cliby WA, et
al: Serine protease HtrA1 modulates chemotherapy-induced
cytotoxicity. J Clin Invest. 116:1994–2004. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
106
|
Clausen T, Southan C and Ehrmann M: The
HtrA family of proteases: Implications for protein composition and
cell fate. Mol Cell. 10:443–455. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
107
|
Klose R, Adam MG, Weis EM, Moll I,
Wüstehube-Lausch J, Tetzlaff F, Oka C, Ehrmann M and Fischer A:
Inactivation of the serine protease HTRA1 inhibits tumor growth by
deregulating angiogenesis. Oncogene. 37:4260–4272. 2018. View Article : Google Scholar : PubMed/NCBI
|
|
108
|
Beaufort N, Scharrer E, Kremmer E, Lux V,
Ehrmann M, Huber R, Houlden H, Werring D, Haffner C and Dichgans M:
Cerebral small vessel disease-related protease HtrA1 processes
latent TGF-β binding protein 1 and facilitates TGF-β signaling.
Proc Natl Acad Sci USA. 111:16496–501. 2014. View Article : Google Scholar
|
|
109
|
Grau S, Richards PJ, Kerr B, Hughes C,
Caterson B, Williams AS, Junker U, Jones SA, Clausen T and Ehrmann
M: The role of human HtrA1 in arthritic disease. J Biol Chem.
281:6124–6129. 2006. View Article : Google Scholar
|
|
110
|
Bhutada S, Hoyle A, Piuzzi NS and Apte SS:
Degradomics defines proteolysis information flow from human knee
osteoarthritis cartilage to matched synovial fluid and the
contributions of secreted proteases ADAMTS5, MMP13 and CMA1 to
articular cartilage breakdown. Osteoarthritis Cartilage.
33:116–127. 2025. View Article : Google Scholar :
|
|
111
|
Tossetta G, Fantone S, Licini C, Marzioni
D and Mattioli-Belmonte M: The multifaced role of HtrA1 in the
development of joint and skeletal disorders. Bone. 157:1163502022.
View Article : Google Scholar : PubMed/NCBI
|
|
112
|
Tiaden AN, Klawitter M, Lux V, Mirsaidi A,
Bahrenberg G, Glanz S, Quero L, Liebscher T, Wuertz K, Ehrmann M
and Richards PJ: Detrimental role for human high temperature
requirement serine protease A1 (HTRA1) in the pathogenesis of
intervertebral disc (IVD) degeneration. J Biol Chem.
287:21335–21345. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
113
|
Malik R, Beaufort N, Li J, Tanaka K,
Georgakis MK, He Y, Koido M, Terao C, Japan B, Anderson CD, et al:
Genetically proxied HTRA1 protease activity and circulating levels
independently predict risk of ischemic stroke and coronary artery
disease. Nat Cardiovasc Res. 3:701–713. 2024. View Article : Google Scholar : PubMed/NCBI
|
|
114
|
Li Y, Ying Y, Yao T, Jia X, Liang H, Tang
W, Jia X, Song H, Shao X, Wang DJJ, et al: Decreased water exchange
rate across blood-brain barrier in hereditary cerebral small vessel
disease. Brain. 146:3079–3087. 2023. View Article : Google Scholar : PubMed/NCBI
|
|
115
|
Beguier F, Housset M, Roubeix C, Augustin
S, Zagar Y, Nous C, Mathis T, Eandi C, Benchaboune M, Drame-Maigné
A, et al: The 10q26 risk haplotype of age-related macular
degeneration aggravates subretinal inflammation by impairing
monocyte elimination. Immunity. 53:2020. View Article : Google Scholar : PubMed/NCBI
|
|
116
|
Jiang Z, Li X, Liu F, Li J, Yang K, Xu S
and Jiang Z: Downregulation of HTRA1 Promotes EMT and anoikis
resistance in colorectal cancer via activation of Hippo/YAP1
pathway by facilitating LATS2 degradation. Mol Carcinog.
64:1330–1346. 2025. View Article : Google Scholar : PubMed/NCBI
|
|
117
|
Eigenbrot C, Ultsch M, Lipari MT, Moran P,
Lin SJ, Ganesan R, Quan C, Tom J, Sandoval W, van Lookeren Campagne
M and Kirchhofer D: Structural and functional analysis of HtrA1 and
its subdomains. Structure. 20:1040–1050. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
118
|
Clawson GA, Bui V, Xin P, Wang N and Pan
W: Intracellular localization of the tumor suppressor HtrA1/Prss11
and its association with HPV16 E6 and E7 proteins. J Cell Biochem.
105:81–88. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
119
|
Xu W, Liu X, Han W, Wu K, Zhao M, Mei T,
Shang B, Wu J, Luo J, Lai Y, et al: Inhibiting HIF-1 signaling
alleviates HTRA1-induced RPE senescence in retinal degeneration.
Cell Commun Signal. 21:1342023. View Article : Google Scholar : PubMed/NCBI
|
|
120
|
Guo F, Tao X, Wu Y, Dong D, Zhu Y, Shang D
and Xiang H: Carfilzomib relieves pancreatitis-initiated pancreatic
ductal adenocarcinoma by inhibiting high-temperature requirement
protein A1. Cell Death Discov. 10:582024. View Article : Google Scholar : PubMed/NCBI
|
|
121
|
Liu W, Liu C, Xiao J, Qian C, Chen Z, Lin
W, Zhang Y, Wu J, Zhou R and Zhao L: HTRA1 interacts with SLC7A11
to modulate colorectal cancer chemosensitivity by inhibiting
ferroptosis. Cell Death Discov. 10:2282024. View Article : Google Scholar : PubMed/NCBI
|
