|
1
|
Lashner BA, Silverstein MD and Hanauer SB:
Hazard rates for dysplasia and cancer in ulcerative colitis.
Results from a surveillance program. Dig Dis Sci. 34:1536–1541.
1989. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ekbom A, Helmick C, Zack M and Adami HO:
Ulcerative colitis and colorectal cancer. A population-based study.
N Engl J Med. 323:1228–1233. 1990. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Eaden JA, Abrams KR and Mayberry JF: The
risk of colorectal cancer in ulcerative colitis: a meta-analysis.
Gut. 48:526–535. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Itzkowitz SH and Present DH: Consensus
conference: colorectal cancer screening and surveillance in
inflammatory bowel disease. Inflamm Bowel Dis. 11:314–321. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Pohl C, Hombach A and Kruis W: Chronic
inflammatory bowel disease and cancer. Hepatogastroenterology.
47:57–70. 2000.PubMed/NCBI
|
|
6
|
Geboes K: Ulcerative colitis and
malignancy. Acta Gastroenterol Belg. 63:279–283. 2000.PubMed/NCBI
|
|
7
|
Provenzale D and Onken J: Surveillance
issues in inflammatory bowel disease: ulcerative colitis. J Clin
Gastroenterol. 32:99–105. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Itzkowitz SH and Yio X: Inflammation and
cancer IV. Colorectal cancer in inflammatory bowel disease: the
role of inflammation. Am J Physiol Gastrointest Liver Physiol.
287:G7–G17. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Garrity-Park MM, Loftus EV Jr, Sandborn
WJ, Bryant SC and Smyrk TC: Methylation status of genes in
non-neoplastic mucosa from patients with ulcerative
colitis-associated colorectal cancer. Am J Gastroenterol.
105:1610–1619. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Issa JP: CpG-island methylation in aging
and cancer. Curr Top Microbiol Immunol. 249:101–118.
2000.PubMed/NCBI
|
|
11
|
Maekita T, Nakazawa K, Mihara M, Nakajima
T, Yanaoka K, Iguchi M, Arii K, Kaneda A, Tsukamoto T, Tatematsu M,
Tamura G, Saito D, Sugimura T, Ichinose M and Ushijima T: High
levels of aberrant DNA methylation in Helicobacter pylori-infected
gastric mucosae and its possible association with gastric cancer
risk. Clin Cancer Res. 12:989–995. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Nakajima T, Maekita T, Oda I, Gotoda T,
Yamamoto S, Umemura S, Ichinose M, Sugimura T, Ushijima T and Saito
D: Higher methylation levels in gastric mucosae significantly
correlate with higher risk of gastric cancers. Cancer Epidemiol
Biomarkers Prev. 15:2317–2321. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kondo Y, Kanai Y, Sakamoto M, Mizokami M,
Ueda R and Hirohashi S: Genetic instability and aberrant DNA
methylation in chronic hepatitis and cirrhosis: a comprehensive
study of loss of heterozygosity and microsatellite instability at
39 loci and DNA hypermethylation on 8 CpG islands in microdissected
specimens from patients with hepatocellular carcinoma. Hepatology.
32:970–979. 2000.
|
|
14
|
Ushijima T: Epigenetic field for
cancerization. J Biochem Mol Biol. 40:142–150. 2007. View Article : Google Scholar
|
|
15
|
Hsieh CJ, Klump B, Holzmann K, Borchard F,
Gregor M and Porschen R: Hypermethylation of the
p16INK4a promoter in colectomy specimens of patients
with long-standing and extensive ulcerative colitis. Cancer Res.
58:3942–3945. 1998.PubMed/NCBI
|
|
16
|
Sato F, Harpaz N, Shibata D, Xu Y, Yin J,
Mori Y, Zou TT, Wang S, Desai K, Leytin A, Selaru FM, Abraham JM
and Meltzer SJ: Hypermethylation of the p14(ARF) gene in ulcerative
colitis-associated colorectal carcinogenesis. Cancer Res.
62:1148–1151. 2002.PubMed/NCBI
|
|
17
|
Issa JP, Ahuja N, Toyota M, Bronner MP and
Brentnall TA: Accelerated age-related CpG island methylation in
ulcerative colitis. Cancer Res. 61:3573–3577. 2001.PubMed/NCBI
|
|
18
|
Fujii S, Tominaga K, Kitajima K, Takeda J,
Kusaka T, Fujita M, Ichikawa K, Tomita S, Ohkura Y, Ono Y, Imura J,
Chiba T and Fujimori T: Methylation of the oestrogen receptor gene
in non-neoplastic epithelium as a marker of colorectal neoplasia
risk in long-standing and extensive ulcerative colitis. Gut.
54:1287–1292. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Gloria L, Cravo M, Pinto A, De Sousa LS,
Chaves P, Leitao CN, Quina M, Mira FC and Soares J: DNA
hypomethylation and proliferative activity are increased in the
rectal mucosa of patients with long-standing ulcerative colitis.
Cancer. 78:2300–2306. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yamamoto F, Yamamoto M, Soto JL, Kojima E,
Wang EN, Perucho M, Sekiya T and Yamanaka H: Notl-Msell
methylation-sensitive amplied fragment length polymorhism for DNA
methylation analysis of human cancers. Electrophoresis.
22:1946–1956. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Samuelsson JK, Alonso S, Yamamoto F and
Perucho M: DNA fingerprinting techniques for the analysis of
genetic and epigenetic alterations in colorectal cancer. Mutat Res.
693:61–76. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Yamashita K, Dai T, Dai Y, Yamamoto F and
Perucho M: Genetics supersedes epigenetics in colon cancer
phenotype. Cancer Cell. 4:121–131. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Suzuki K, Suzuki I, Leodolter A, Alonso S,
Horiuchi S, Yamashita K and Perucho M: Global DNA demethylation in
gastrointestinal cancer is age dependent and precedes genomic
damage. Cancer Cell. 9:199–207. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Kageyama S, Shinmura K, Yamamoto H, Goto
M, Suzuki K, Tanioka F, Tsuneyoshi T and Sugimura H:
Fluorescence-labeled methylation-sensitive amplified fragment
length polymorphism (FL-MS-AFLP) analysis for quantitative
determination of DNA methylation and demethylation status. Jpn J
Clin Oncol. 38:317–322. 2008. View Article : Google Scholar
|
|
25
|
Irizarry RA, Ladd-Acosta C, Wen B, Wu Z,
Montano C, Onyango P, Cui H, Gabo K, Rongione M, Webster M, Ji H,
Potash JB, Sabunciyan S and Feinberg AP: The human colon cancer
methylome shows similar hypo- and hypermethylation at conserved
tissue-specific CpG island shores. Nat Genet. 41:178–186. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Ehrlich M: DNA methylation in cancer: too
much, but also too little. Oncogene. 21:5400–5413. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Yamamoto F and Yamamoto M: A DNA
microarray-based methylation-sensitive (MS)-AFLP hybridization
method for genetic and epigenetic analyses. Mol Genet Genomics.
271:678–686. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Rouillard JM, Zuker M and Gulari E:
OligoArray 2.0: design of oligonucleotide probes for DNA
microarrays using a thermodynamic approach. Nucleic Acids Res.
31:3057–3062. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Team RDC: R: A language and environment
for statistical computing. R Foundation for Statistical Computing;
Vienna: 2009
|
|
30
|
Frommer M, McDonald LE, Millar DS, Collis
CM, Watt F, Grigg GW, Molloy PL and Paul CL: A genomic sequencing
protocol that yields a positive display of 5-methylcytosine
residues in individual DNA strands. Proc Natl Acad Sci USA.
89:1827–1831. 1992. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Holm S: A simple sequentially rejective
multiple test procedure. Scand J Statist. 6:65–70. 1979.
|
|
32
|
Saeed AI, Sharov V, White J, Li J, Liang
W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M,
Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E,
Borisovsky I, Liu Z, Vinsavich A, Trush V and Quackenbush J: TM4: a
free, open-source system for microarray data management and
analysis. Biotechniques. 34:374–378. 2003.PubMed/NCBI
|
|
33
|
Huang da W, Sherman BT and Lempicki RA:
Systematic and integrative analysis of large gene lists using DAVID
bioinformatics resources. Nat Protoc. 4:44–57. 2009.PubMed/NCBI
|
|
34
|
Huang da W, Sherman BT, Tan Q, Kir J, Liu
D, Bryant D, Guo Y, Stephens R, Baseler MW, Lane HC and Lempicki
RA: DAVID Bioinformatics Resources: expanded annotation database
and novel algorithms to better extract biology from large gene
lists. Nucleic Acids Res. 35:W169–W175. 2007.PubMed/NCBI
|
|
35
|
Hosack DA, Dennis G Jr, Sherman BT, Lane
HC and Lempicki RA: Identifying biological themes within lists of
genes with EASE. Genome Biol. 4:R702003. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Ionov Y, Peinado MA, Malkhosyan S, Shibata
D and Perucho M: Ubiquitous somatic mutations in simple repeated
sequences reveal a new mechanism for colonic carcinogenesis.
Nature. 363:558–561. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Kanehisa M and Goto S: KEGG: kyoto
encyclopedia of genes and genomes. Nucleic Acids Res. 28:27–30.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kawakami K, Matsunoki A, Kaneko M, Saito
K, Watanabe G and Minamoto T: Long interspersed nuclear element-1
hypomethylation is a potential biomarker for the prediction of
response to oral fluoropyrimidines in microsatellite stable and CpG
island methylator phenotype-negative colorectal cancer. Cancer Sci.
102:166–174. 2011. View Article : Google Scholar
|
|
39
|
Toyota M, Ahuja N, Ohe-Toyota M, Herman
JG, Baylin SB and Issa JP: CpG island methylator phenotype in
colorectal cancer. Proc Natl Acad Sci USA. 96:8681–8686. 1999.
View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Smiraglia DJ, Rush LJ, Fruhwald MC, Dai Z,
Held WA, Costello JF, Lang JC, Eng C, Li B, Wright FA, Caligiuri MA
and Plass C: Excessive CpG island hypermethylation in cancer cell
lines versus primary human malignancies. Hum Mol Genet.
10:1413–1419. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Perucho M, Tokino T and Nakamura Y: Cancer
genomics and molecular diagnosis - The Nineteenth International
Symposium of Sapporo Cancer Seminar. Jpn J Cancer Res.
90:1273–1276. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Raman V, Martensen SA, Reisman D, Evron E,
Odenwald WF, Jaffee E, Marks J and Sukumar S: Compromised HOXA5
function can limit p53 expression in human breast tumours. Nature.
405:974–978. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Shiraishi M, Sekiguchi A, Oates AJ, Terry
MJ and Miyamoto Y: HOX gene clusters are hotspots of de novo
methylation in CpG islands of human lung adenocarcinomas. Oncogene.
21:3659–3662. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Shah N and Sukumar S: The Hox genes and
their roles in oncogenesis. Nat Rev Cancer. 10:361–371. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Vire E, Brenner C, Deplus R, Blanchon L,
Fraga M, Didelot C, Morey L, van Eynde A, Bernard D, Vanderwinden
JM, Bollen M, Esteller M, Di Croce L, De Launoit Y and Fuks F: The
Polycomb group protein EZH2 directly controls DNA methylation.
Nature. 439:871–874. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Schlesinger Y, Straussman R, Keshet I,
Farkash S, Hecht M, Zimmerman J, Eden E, Yakhini Z, Ben-Shushan E,
Reubinoff BE, Bergman Y, Simon I and Cedar H: Polycomb-mediated
methylation on Lys27 of histone H3 pre-marks genes for de novo
methylation in cancer. Nat Genet. 39:232–236. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Widschwendter M, Fiegl H, Egle D,
Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M,
Young J, Jacobs I and Laird PW: Epigenetic stem cell signature in
cancer. Nat Genet. 39:157–158. 2007. View
Article : Google Scholar
|
|
48
|
Rodriguez J, Vives L, Jorda M, Morales C,
Munoz M, Vendrell E and Peinado MA: Genome-wide tracking of
unmethylated DNA Alu repeats in normal and cancer cells. Nucleic
Acids Res. 36:770–784. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Mazumdar T, De Vecchio J, Shi T, Jones J,
Agyeman A and Houghton JA: Hedgehog signaling drives cellular
survival in human colon carcinoma cells. Cancer Res. 71:1092–1102.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Hanigan CL, Van Engeland M, De Bruine AP,
Wouters KA, Weijenberg MP, Eshleman JR and Herman JG: An
inactivating mutation in HDAC2 leads to dysregulation of apoptosis
mediated by APAF1. Gastroenterology. 135:1652–1664. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Slattery ML, Lundgreen A, Herrick JS, Caan
BJ, Potter JD and Wolff RK: Associations between genetic variation
in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal
cancer: additional support for a TGF-beta-signaling pathway.
Carcinogenesis. 32:318–326. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Koinuma K, Yamashita Y, Liu W, Hatanaka H,
Kurashina K, Wada T, Takada S, Kaneda R, Choi YL, Fujiwara SI,
Miyakura Y, Nagai H and Mano H: Epigenetic silencing of AXIN2 in
colorectal carcinoma with microsatellite instability. Oncogene.
25:139–146. 2006.PubMed/NCBI
|
|
53
|
Liu W, Dong X, Mai M, Seelan RS, Taniguchi
K, Krishnadath KK, Halling KC, Cunningham JM, Boardman LA, Qian C,
Christensen E, Schmidt SS, Roche PC, Smith DI and Thibodeau SN:
Mutations in AXIN2 cause colorectal cancer with defective mismatch
repair by activating beta-catenin/TCF signalling. Nat Genet.
26:146–147. 2000. View
Article : Google Scholar : PubMed/NCBI
|
|
54
|
Meira LB, Bugni JM, Green SL, Lee CW, Pang
B, Borenshtein D, Rickman BH, Rogers AB, Moroski-Erkul CA, McFaline
JL, Schauer DB, Dedon PC, Fox JG and Samson LD: DNA damage induced
by chronic inflammation contributes to colon carcinogenesis in
mice. J Clin Invest. 118:2516–2525. 2008.PubMed/NCBI
|
|
55
|
Killian A, Sarafan-Vasseur N, Sesboue R,
Le Pessot F, Blanchard F, Lamy A, Laurent M, Flaman JM and Frebourg
T: Contribution of the BOP1 gene, located on 8q24, to colorectal
tumorigenesis. Genes Chromosomes Cancer. 45:874–881. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
56
|
Matts SG: The value of rectal biopsy in
the diagnosis of ulcerative colitis. Q J Med. 30:393–407.
1961.PubMed/NCBI
|
