|
1
|
Ying SY: Inhibins and activins: chemical
properties and biological activity. Proc Soc Exp Biol Med.
186:253–264. 1987. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Ying SY: Inhibins, activins, follistatins:
gonadal proteins modulating the secretion of follicle-stimulating
hormone. Endocr Rev. 9:267–293. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Robertson DM, Giacometti M, Foulds LM,
Lahnstein J, Goss NH, Hearn MTW and de Kretser DM: Isolation of
inhibin α-subunit precursor proteins from bovine follicular fluid.
Endocrinology. 125:2141–2149. 1989.
|
|
4
|
Hotten G, Neidhardt H, Schneider C and
Pohl J: Cloning of a new member of the TGF-β family: a putative new
activin βC chain. Biochem Biophys Res Commun.
206:608–613. 1995.
|
|
5
|
Oda S, Nishimatsu S, Murakami K and Ueno
N: Molecular cloning and functional analysis of a new activin β
subunit: a dorsal mesoderm-inducing activity in Xenopus.
Biochem Biophys Res Commun. 210:581–588. 1995.
|
|
6
|
Fang J, Yin W, Smiley E, Wang SQ and
Bonadio J: Molecular cloning of the mouse activin βE
subunit gene. Biochem Biophys Res Commun. 228:669–674. 1996.
|
|
7
|
de Kretser DM, Hedger MP, Loveland KL and
Phillips DJ: Inhibins, activins and follistatin in reproduction.
Hum Reprod Update. 8:529–541. 2002.PubMed/NCBI
|
|
8
|
Findlay JK, Drummond AE, Dyson ML, Baillie
AJ, Robertson DM and Ethier JF: Recruitment and development of the
follicle; the roles of the transforming growth factor-β
superfamily. Mol Cell Endocrinol. 191:35–43. 2002.
|
|
9
|
Juengel JL and McNatty KP: The role of
proteins of the transforming growth factor-β superfamily in the
intraovarian regulation of follicular development. Hum Reprod
Update. 11:144–161. 2005.
|
|
10
|
Knight PG and Glister C: TGF-β superfamily
members and ovarian follicle development. Reproduction.
132:191–206. 2006.
|
|
11
|
Chand AL, Ooi GT, Harrison CA, Shelling AN
and Robertson DM: Functional analysis of the human inhibin α
subunit variant A257T and its potential role in premature ovarian
failure. Hum Reprod. 22:3241–3248. 2007.
|
|
12
|
Welt CK, Taylor AE, Fox J, Messerlian GM,
Adams JM and Schneyer AL: Follicular arrest in polycystic ovary
syndrome is associated with deficient inhibin A and B biosynthesis.
J Clin Endocrinol Metab. 90:5582–5587. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Hamar BD, Buhimschi IA, Sfakianaki AK,
Pettker CM, Magloire LK, Funai EF, Copel JA and Buhimschi CS: Serum
and urine inhibin A but not free activin A are endocrine biomarkers
of severe pre-eclampsia. Am J Obstet Gynecol. 195:1636–1645. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Tsigkou A, Marrelli D, Reis FM, et al:
Total inhibin is a potential serum marker for epithelial ovarian
cancer. J Clin Endocrinol Metab. 92:2526–2531. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Tsigkou A, Luisi S, Reis FM and Petraglia
F: Inhibins as diagnostic markers in human reproduction. Adv Clin
Chem. 45:1–29. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Cho BN, McMullen ML, Pei L, Yates CJ and
Mayo KE: Reproductive deficiencies in transgenic mice expressing
the rat inhibin α-subunit gene. Endocrinology. 142:4994–5004.
2001.PubMed/NCBI
|
|
17
|
Ahn JM, Jung HK, Cho C, Choi D, Mayo KE
and Cho BN: Changes in the reproductive functions of mice due to
injection of a plasmid expressing an inhibin α-subunit into muscle:
a transient transgenic model. Mol Cell. 18:79–86. 2004.PubMed/NCBI
|
|
18
|
Luisi S, Florio P, Reis FM and Petraglia
F: Inhibins in female and male reproductive physiology: role in
gametogenesis, conception, implantation and early pregnancy. Hum
Reprod Update. 11:123–135. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Risbridger GP, Schmitt JF and Robertson
DM: Activins and inhibins in endocrine and other tumors. Endocr
Rev. 22:836–858. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Matzuk MM, Finegold MJ, Su JG, Hsueh AJ
and Bradley A: α-inhibin is a tumour-suppressor gene with gonadal
specificity in mice. Nature. 360:313–319. 1992.
|
|
21
|
Matzuk MM and Bradley A: Identification
and analysis of tumor suppressor genes using transgenic mouse
models. Semin Cancer Biol. 5:37–45. 1994.PubMed/NCBI
|
|
22
|
Matzuk MM, Finegold MJ, Mather JP, Krummen
L, Lu H and Bradley A: Development of cancer cachexia-like syndrome
and adrenal tumors in inhibin-deficient mice. Proc Natl Acad Sci
USA. 91:8817–8821. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Schmitt JF, Millar DS, Pedersen JS, et al:
Hypermethylation of the inhibin α-subunit gene in prostate
carcinoma. Mol Endocrinol. 16:213–220. 2002.
|
|
24
|
Balanathan P, Ball EMA, Wang H, Harris SE,
Shelling AN and Risbridger GP: Epigenetic regulation of inhibin
α-subunit gene in prostate cancer cell lines. J Mol Endocrinol.
32:55–67. 2004.
|
|
25
|
Balanathan P, Williams ED, Wang H, et al:
Elevated level of inhibin-α subunit is pro-tumourigenic and
pro-metastatic and associated with extracapsular spread in advanced
prostate cancer. Br J Cancer. 100:1784–1793. 2009.
|
|
26
|
Imai K, Khandoker MAM, Yonai M, et al:
Matrix metalloproteinases-2 and -9 activities in bovine follicular
fluid of different-sized follicles: relationship to
intra-follicular inhibin and steroid concentrations. Domest Anim
Endocrinol. 24:171–183. 2003. View Article : Google Scholar
|
|
27
|
Jones RL, Findlay JK, Farnworth PG,
Robertson DM, Wallace E and Salamonsen LA: Activin A and inhibin A
differentially regulate human uterine matrix metalloproteinases:
potential interactions during decidualization and trophoblast
invasion. Endocrinology. 147:724–732. 2006. View Article : Google Scholar
|
|
28
|
Hempel N, How T, Dong M, Murphy SK, Fields
TA and Blobe GC: Loss of betaglycan expression in ovarian cancer:
role in motility and invasion. Cancer Res. 67:5231–5238. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Clark SJ, Harrison J, Paul CL and Frommer
M: High sensitivity mapping of methylated cytosines. Nucleic Acids
Res. 22:2990–2997. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Sundblad V, Chiauzzi VA, Andreone L, Campo
S, Charreau EH and Dain L: Controversial role of inhibin α-subunit
gene in the aetiology of premature ovarian failure. Hum Reprod.
21:1154–1160. 2006.
|
|
31
|
Jones PA and Baylin SB: 2002.The
fundamental role of epigenetic events in cancer. Nat Rev Genet.
3:415–428. 2002.PubMed/NCBI
|
|
32
|
Song SH, Jong HS, Choi HH, Inoue H, Tanabe
T, Kim NK and Bang YJ: Transcriptional silencing of
cyclooxygenase-2 by hyper-methylation of the 5′ CpG island in human
gastric carcinoma cells. Cancer Res. 61:4628–4635. 2001.PubMed/NCBI
|
|
33
|
Kuchler RJ: Development of animal cell
populations in vitro. Biochemical Methods in Cell Culture and
Virology. Kuchler RJ: Dowden, Hutchinson and Ross Inc. Press;
Stroudsburg, PA: pp. 90–113. 1977
|
|
34
|
Garinis GA, Patrinos GP, Spanakis NE and
Menounos PG: DNA hypermethylation: when tumour suppressor genes go
silent. Hum Genet. 111:115–127. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Watson RH, Roy WJ, Davis M, Hitchcock A
and Campbell IG: Loss of heterozygosity at the α-inhibin locus on
chromosome 2q is not a feature of human granulosa cell tumors.
Gynecol Oncol. 65:387–390. 1997.
|
|
36
|
Marozzi A, Porta C, Vegetti W, Crosignani
PG, Tibiletti MG, Dalpra L and Ginelli E: Mutation analysis of the
inhibin alpha gene in a cohort of Italian women affected by ovarian
failure. Hum Reprod. 17:1741–1745. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Stenvers KL and Findlay JK: Inhibins: from
reproductive hormones to tumor suppressors. Trends Endocrinol
Metab. 21:174–180. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Barton DE, Yang-Feng TL, Mason AJ, Seeburg
PH and Francke U: Mapping of genes for inhibin subunits α,
βA, and βB on human and mouse chromosomes and
studies of jsd mice. Genomics. 5:91–99. 1898.
|
|
39
|
Mellor SL, Richards MG, Pedersen JS,
Robertson DM and Risbridger GP: Loss of the expression and
localization of inhibin α-subunit in high grade prostate cancer. J
Clin Endocrinol Metab. 83:969–975. 1998.
|
|
40
|
Vitale AM, Gonzalez OM, Parborell F,
Irusta G, Campo S and Tesone M: Inhibin A increases apoptosis in
early ovarian antral follicles of diethylstilbestrol-treated rats.
Biol Reprod. 67:1989–1995. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Steller MD, Shaw TJ, Vanderhyden BC and
Ethier JF: Inhibin resistance is associated with aggressive
tumorigenicity of ovarian cancer cells. Mol Cancer Res. 3:50–61.
2005.PubMed/NCBI
|
|
42
|
Geng LY, Fang M, Yi JM, Jiang F,
Moeen-ud-Din M and Yang LG: Effect of overexpression of inhibin α
(1–32) fragment on bovine granulosa cell proliferation, apoptosis,
steroidogenesis, and development of co-cultured oocytes.
Theriogenology. 70:35–43. 2008.
|
|
43
|
Myers M, Middlebrook BS, Matzuk MM and
Pangas SA: Loss of inhibin alpha uncouples oocyte-granulosa cell
dynamics and disrupts postnatal folliculogenesis. Dev Biol.
334:458–467. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Oka M, Meacham AM, Hamazaki T, Rodić N,
Chang LJ and Terada N: De novo DNA methyltransferases Dnmt3a
and Dnmt3b primarily mediate the cytotoxic effect of
5-aza-2′-deoxycytidine. Oncogene. 24:3091–3099. 2005. View Article : Google Scholar
|
|
45
|
Fulda S and Debatin KM:
5-Aza-2′-deoxycytidine and IFN-γ cooperate to sensitize for
TRAIL-induced apoptosis by upregulating caspase-8. Oncogene.
25:5125–5133. 2006.
|
|
46
|
Valdez BC, Li Y, Murray D, Corn P,
Champlin RE and Andersson BS: 5-Aza-2′-deoxycytidine sensitizes
busulfan-resistant myeloid leukemia cells by regulating expression
of genes involved in cell cycle checkpoint and apoptosis. Leuk Res.
34:364–372. 2010.
|
|
47
|
Hanahan D and Weinberg RA: Hallmarks of
cancer: the next generation. Cell. 144:646–674. 2011. View Article : Google Scholar : PubMed/NCBI
|
