1.
|
Nord H, Hartmann C, Andersson R, et al:
Characterization of novel and complex genomic aberrations in
glioblastoma using a 32K BAC array. Neurooncology. 11:803–818.
2009.PubMed/NCBI
|
2.
|
Gracia E, Fischer U, elKahloun A, Trent
JM, Meese E and Meltzer PS: Isolation of genes amplified in human
cancers by microdissection mediated cDNA capture. Hum Mol Genet.
5:595–600. 1996. View Article : Google Scholar : PubMed/NCBI
|
3.
|
Fischer U, Heckel D, Michel A, Janka M,
Hulsebos T and Meese E: Cloning of a novel transcription
factor-like gene amplified in human glioma including astrocytoma
grade I. Hum Mol Genet. 6:1817–1822. 1997. View Article : Google Scholar : PubMed/NCBI
|
4.
|
Fischer U, Hemmer D, Heckel D, et al: KUB3
amplification and overexpression in human gliomas. Glia. 36:1–10.
2001. View Article : Google Scholar : PubMed/NCBI
|
5.
|
Maas RM, Reus K, Diesel B, et al:
Amplification and expression of splice variants of the gene
encoding the P450 cytochrome 25-hydroxyvitamin D(3)
1,alpha-hydroxylase (CYP 27B1) in human malignant glioma. Clin
Cancer Res. 7:868–875. 2001.
|
6.
|
Yang CR, Yeh S, Leskov K, et al: Isolation
of Ku70-binding proteins (KUBs). Nucleic Acids Res. 27:2165–2174.
1999. View Article : Google Scholar : PubMed/NCBI
|
7.
|
Olive PL: The role of DNA single- and
double-strand breaks in cell killing by ionizing radiation. Radiat
Res. 150:S42–S51. 1998. View
Article : Google Scholar : PubMed/NCBI
|
8.
|
Hoeijmakers JH: Genome maintenance
mechanisms for preventing cancer. Nature. 411:366–374. 2001.
View Article : Google Scholar : PubMed/NCBI
|
9.
|
van Gent DC, Hoeijmakers JH and Kanaar R:
Chromosomal stability and the DNA double-stranded break connection.
Nat Rev Genet. 2:196–206. 2001.
|
10.
|
Jackson SP: Sensing and repairing DNA
double-strand breaks. Carcinogenesis. 23:687–696. 2002. View Article : Google Scholar : PubMed/NCBI
|
11.
|
Calsou P, Delteil C, Frit P, Drouet J and
Salles B: Coordinated assembly of Ku and p460 subunits of the
DNA-dependent protein kinase on DNA ends is necessary for
XRCC4-ligase IV recruitment. J Mol Biol. 326:93–103. 2003.
View Article : Google Scholar : PubMed/NCBI
|
12.
|
Drouet J, Delteil C, Lefrancois J,
Concannon P, Salles B and Calsou P: DNA-dependent protein kinase
and XRCC4-DNA ligase IV mobilization in the cell in response to DNA
double-strand breaks. J Biol Chem. 280:7060–7069. 2005. View Article : Google Scholar : PubMed/NCBI
|
13.
|
Grawunder U, Zimmer D, Fugmann S, Schwarz
K and Lieber MR: DNA ligase IV is essential for V(D)J recombination
and DNA double-strand break repair in human precursor lymphocytes.
Mol Cell. 2:477–484. 1998. View Article : Google Scholar : PubMed/NCBI
|
14.
|
Li Z, Otevrel T, Gao Y, et al: The XRCC4
gene encodes a novel protein involved in DNA double-strand break
repair and V(D)J recombination. Cell. 83:1079–1089. 1995.
View Article : Google Scholar : PubMed/NCBI
|
15.
|
Fischer U, Leidinger P, Keller A, et al:
Amplicons on chromosome 12q13-21 in glioblastoma recurrences. Int J
Cancer. 126:2594–2602. 2010.PubMed/NCBI
|
16.
|
Diesel B, Radermacher J, Bureik M, et al:
Vitamin D(3) metabolism in human glioblastoma multiforme:
functionality of CYP27B1 splice variants, metabolism of calcidiol
and effect of calcitriol. Clin Cancer Res. 11:5370–5380. 2005.
View Article : Google Scholar : PubMed/NCBI
|
17.
|
Fischer U, Muller HW, Sattler HP, Feiden
K, Zang KD and Meese E: Amplification of the MET gene in glioma.
Genes Chromosomes Cancer. 12:63–65. 1995. View Article : Google Scholar
|
18.
|
Ogawa K, Murayama S and Mori M: Predicting
the tumor response to radiotherapy using microarray analysis
(Review). Oncol Rep. 18:1243–1248. 2007.PubMed/NCBI
|
19.
|
Wilson CR, Davidson SE, Margison GP,
Jackson SP, Hendry JH and West CM: Expression of Ku70 correlates
with survival in carcinoma of the cervix. Br J Cancer.
83:1702–1706. 2000. View Article : Google Scholar : PubMed/NCBI
|
20.
|
Moll U, Lau R, Sypes MA, Gupta MM and
Anderson CW: DNA-PK, the DNA-activated protein kinase, is
differentially expressed in normal and malignant human tissues.
Oncogene. 18:3114–3126. 1999. View Article : Google Scholar : PubMed/NCBI
|
21.
|
Hosoi Y, Watanabe T, Nakagawa K, et al:
Up-regulation of DNA-dependent protein kinase activity and Sp1 in
colorectal cancer. Int J Oncol. 25:461–468. 2004.PubMed/NCBI
|
22.
|
Sakata K, Matsumoto Y, Satoh M, et al:
Clinical studies of immunohistochemical staining of DNA-dependent
protein kinase in oropharyngeal and hypopharyngeal carcinomas.
Radiat Med. 19:93–97. 2001.PubMed/NCBI
|
23.
|
Shintani S, Mihara M, Li C, et al:
Up-regulation of DNA-dependent protein kinase correlates with
radiation resistance in oral squamous cell carcinoma. Cancer Sci.
94:894–900. 2003. View Article : Google Scholar : PubMed/NCBI
|
24.
|
Stronati L, Gensabella G, Lamberti C, et
al: Expression and DNA binding activity of the Ku heterodimer in
bladder carcinoma. Cancer. 92:2484–2492. 2001. View Article : Google Scholar : PubMed/NCBI
|
25.
|
Fuhrman CB, Kilgore J, LaCoursiere YD, et
al: Radiosensitization of cervical cancer cells via double-strand
DNA break repair inhibition. Gynecol Oncol. 110:93–98. 2008.
View Article : Google Scholar : PubMed/NCBI
|
26.
|
Lees-Miller SP, Godbout R, Chan DW, et al:
Absence of p350 subunit of DNA-activated protein kinase from a
radiosensitive human cell line. Science. 267:1183–1185. 1995.
View Article : Google Scholar : PubMed/NCBI
|
27.
|
Hoppe BS, Jensen RB and Kirchgessner CU:
Complementation of the radiosensitive M059J cell line. Radiat Res.
153:125–130. 2000. View Article : Google Scholar : PubMed/NCBI
|
28.
|
Tian X, Chen G, Xing H, Weng D, Guo Y and
Ma D: The relationship between the down-regulation of DNA-PKcs or
Ku70 and the chemosensitization in human cervical carcinoma cell
line HeLa. Oncol Rep. 18:927–932. 2007.PubMed/NCBI
|
29.
|
Short SC, Martindale C, Bourne S, Brand G,
Woodcock M and Johnston P: DNA repair after irradiation in glioma
cells and normal human astrocytes. Neurooncology. 9:404–411.
2007.PubMed/NCBI
|
30.
|
Ohgaki H and Kleihues P: Genetic pathways
to primary and secondary glioblastoma. Am J Pathol. 170:1445–1453.
2007. View Article : Google Scholar : PubMed/NCBI
|
31.
|
Hegi ME, Diserens AC, Gorlia T, et al:
MGMT gene silencing and benefit from temozolomide in glioblastoma.
N Engl J Med. 352:997–1003. 2005. View Article : Google Scholar : PubMed/NCBI
|
32.
|
Hegi ME, Diserens AC, Godard S, et al:
Clinical trial substantiates the predictive value of
O-6-methylguanine-DNA methyltransferase promoter methylation in
glioblastoma patients treated with temozolomide. Clin Cancer Res.
10:1871–1874. 2004. View Article : Google Scholar : PubMed/NCBI
|
33.
|
Zheng M, Bocangel D, Ramesh R, et al:
Interleukin-24 overcomes temozolomide resistance and enhances cell
death by down-regulation of O6-methylguanine-DNA methyltransferase
in human melanoma cells. Mol Cancer Ther. 7:3842–3851. 2008.
View Article : Google Scholar : PubMed/NCBI
|
34.
|
Buck D, Malivert L, de Chasseval R, et al:
Cernunnos, a novel nonhomologous end-joining factor, is mutated in
human immunodeficiency with microcephaly. Cell. 124:287–299. 2006.
View Article : Google Scholar : PubMed/NCBI
|
35.
|
Gellert M: V(D)J recombination: RAG
proteins, repair factors and regulation. Annu Rev Biochem.
71:101–132. 2002. View Article : Google Scholar : PubMed/NCBI
|
36.
|
Rooney S, Sekiguchi J, Zhu C, et al: Leaky
Scid phenotype associated with defective V(D)J coding end
processing in Artemis-deficient mice. Mol Cell. 10:1379–1390. 2002.
View Article : Google Scholar : PubMed/NCBI
|
37.
|
Moshous D, Callebaut I, de Chasseval R, et
al: Artemis, a novel DNA double-strand break repair/V(D)J
recombination protein, is mutated in human severe combined immune
deficiency. Cell. 105:177–186. 2001. View Article : Google Scholar : PubMed/NCBI
|
38.
|
Nussenzweig A, Chen C, da Costa Soares V,
et al: Requirement for Ku80 in growth and immunoglobulin V(D)J
recombination. Nature. 382:551–555. 1996. View Article : Google Scholar : PubMed/NCBI
|
39.
|
Zhu C, Bogue MA, Lim DS, Hasty P and Roth
DB: Ku86-deficient mice exhibit severe combined immunodeficiency
and defective processing of V(D)J recombination intermediates.
Cell. 86:379–389. 1996. View Article : Google Scholar : PubMed/NCBI
|
40.
|
Gao Y, Chaudhuri J, Zhu C, Davidson L,
Weaver DT and Alt FW: A targeted DNA-PKcs-null mutation reveals
DNA-PK-independent functions for KU in V(D)J recombination.
Immunity. 9:367–376. 1998. View Article : Google Scholar : PubMed/NCBI
|
41.
|
Kurimasa A, Kumano S, Boubnov NV, et al:
Requirement for the kinase activity of human DNA-dependent protein
kinase catalytic subunit in DNA strand break rejoining. Mol Cell
Biol. 19:3877–3884. 1999.PubMed/NCBI
|
42.
|
Frank KM, Sekiguchi JM, Seidl KJ, et al:
Late embryonic lethality and impaired V(D)J recombination in mice
lacking DNA ligase IV. Nature. 396:173–177. 1998. View Article : Google Scholar : PubMed/NCBI
|
43.
|
Bassing CH and Alt FW: The cellular
response to general and programmed DNA double-strand breaks. DNA
Repair. 3:781–796. 2004. View Article : Google Scholar : PubMed/NCBI
|
44.
|
Rooney S, Chaudhuri J and Alt FW: The role
of the non-homologous end-joining pathway in lymphocyte
development. Immunol Rev. 200:115–131. 2004. View Article : Google Scholar : PubMed/NCBI
|