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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2013 Volume 43 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

The role of tumor-associated macrophages in breast cancer progression (Review)

Elias Obeid, Rita Nanda, Yang-Xin Fu, Olufunmilayo I. Olopade
Pages: 5-12
Published online on: 14 May 2013

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Article Open Access

Analyses of the combination of 6-MP and dasatinib in cell culture

Gurmeet Kaur, Holger Behrsing, Ralph E. Parchment, Myrtle Davis Millin, Beverly A. Teicher
Pages: 13-22
Published online on: 02 May 2013

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Article Open Access

Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age

Mathias Hoiczyk, Florian Grabellus, Lars Podleska, Marit Ahrens, Benjamin Schwindenhammer, Georg Taeger, Christoph Pöttgen, Martin Schuler, Sebastian Bauer
Pages: 23-28
Published online on: 02 May 2013

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Article Open Access

ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells

Ga Bin Park, Yunock Choi, Yeong Seok Kim, Hyun-Kyung Lee, Daejin Kim, Dae Young Hur
Pages: 29-38
Published online on: 20 May 2013

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 39-49
Published online on: 09 May 2013

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Article Open Access

Glioma-amplified sequence KUB3 influences double-strand break repair after ionizing radiation

Ulrike Fischer, Stefanie Rheinheimer, Andrea Krempler, Markus Löbrich, Eckart Meese
Pages: 50-56
Published online on: 13 May 2013

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Article

Identification of APN/CD13 as the target antigen of FU3, a human monoclonal antibody that recognizes malignant fibrous histiocytoma

Mikiko Aoki, Kazuki Nabeshima, Hiroyuki Hayashi, Makoto Hamasaki, Hiroshi Iwasaki
Pages: 57-62
Published online on: 16 May 2013

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Article

Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells

Ikue Nakayama, Masahiko Shibazaki, Akiko Yashima-Abo, Fumiharu Miura, Toru Sugiyama, Tomoyuki Masuda, Chihaya Maesawa
Pages: 63-71
Published online on: 13 May 2013

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Article

Prx1 modulates the chemosensitivity of lung cancer to docetaxel through suppression of FOXO1-induced apoptosis

Ki-Eun Hwang, Do-Sim Park, Young-Suk Kim, Byoung-Ryun Kim, Seong-Nam Park, Mi-Kyung Lee, Seong-Hoon Park, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 72-78
Published online on: 24 April 2013

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Article

Effect of a novel bladder preservation therapy, BOAI-CDDP-radiation (OMC-regimen)

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Hayahito Nomi, Hiroshi Uehara, Kazumasa Komura, Koichiro Minami, Junko Kouno, Yatsugu Kotake, Hirokazu Abe, Shizuko Takagi, Kazuhiro Yamamoto, Yoshihumi Narumi, Satoshi Kiyama
Pages: 79-87
Published online on: 26 April 2013

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Article

Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis

Mitsuhiro Hishida, Shuji Nomoto, Yoshikuni Inokawa, Masamichi Hayashi, Mitsuro Kanda, Yukiyasu Okamura, Yoko Nishikawa, Chie Tanaka, Daisuke Kobayashi, Suguru Yamada, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Shin Takeda, Yasuhiro Kodera
Pages: 88-94
Published online on: 20 May 2013

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Article

Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas

Manuela Salerno, Sofia Avnet, Gloria Bonuccelli, Adriana Eramo, Ruggero De Maria, Marco Gambarotti, Gabriella Gamberi, Nicola Baldini
Pages: 95-102
Published online on: 01 May 2013

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Article

Primary resistance phenomena to oncolytic measles vaccine viruses

Markus Noll, Susanne Berchtold, Johanna Lampe, Nisar P. Malek, Michael Bitzer, Ulrich M. Lauer
Pages: 103-112
Published online on: 23 April 2013

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Article

Epithelial-mesenchymal transition triggers cancer stem cell generation in human thyroid cancer cells

Ling Lan, Yong Luo, Dai Cui, Bing-Yin Shi, Wei Deng, Li-Li Huo, Hai-Ling Chen, Guo-Ying Zhang, Li-Li Deng
Pages: 113-120
Published online on: 22 April 2013

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Article

Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells

Patrizia Portanova, Antonietta Notaro, Ornella Pellerito, Selenia Sabella, Michela Giuliano, Giuseppe Calvaruso
Pages: 121-130
Published online on: 17 May 2013

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Article

Hypoxia promotes radioresistance of CD133-positive Hep-2 human laryngeal squamous carcinoma cells in vitro

Maoxin Wang, Xiaoming Li, Yongtao Qu, Ou Xu, Qingjia Sun
Pages: 131-140
Published online on: 02 May 2013

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Article

Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells

Hui-Jye Chen, Yi-Lin Jiang, Chung-Ming Lin, Shih-Chang Tsai, Shu-Fen Peng, Shinji Fushiya, Mann-Jen Hour, Jai-Sing Yang
Pages: 141-150
Published online on: 16 May 2013

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Article

Enhancing HSP70-ShRNA transfection in 22RV1 prostate cancer cells by combination of sonoporation, liposomes and HTERT/CMV chimeric promoter

Yun Hua Li, Li Fang Jin, Lian-Fang Du, Qiu Sheng Shi, Long Liu, Xiao Jia, Ying Wu, Fan Li, Hang Hui Wang
Pages: 151-158
Published online on: 25 April 2013

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Article

RNA interference-mediated knockdown of Livin suppresses cell proliferation and invasion and enhances the chemosensitivity to cisplatin in human osteosarcoma cells

Xu Li, Shuli Fan, Leiming Li, Liguo Wang, Guangyu Fan, Qun Zhao, Yan Li
Pages: 159-168
Published online on: 30 April 2013

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Article

Insertional activation of myb by F-MuLV in SCID mice induces myeloid leukemia

Mehran Haeri, Youjun Li, Yanmei Li, Qi Li, David E. Spaner, Yaacov Ben-David
Pages: 169-176
Published online on: 16 May 2013

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Article

Study on molecular imaging and radionuclide therapy of human nasopharyngeal carcinoma cells transfected with baculovirus-mediated sodium/iodine symporter gene

Jianzhang Wang, Shuai Liu, Jun Wang, Yifan Zhang, Biao Li, Changping Cai, Shili Wang
Pages: 177-184
Published online on: 13 May 2013

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Article

Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells

Nadège Kindt, Guy Laurent, Denis Nonclercq, Fabrice Journé, Ghanem Ghanem, Hugues Duvillier, Hans-Joachim Gabius, Jérôme Lechien, Sven Saussez
Pages: 185-193
Published online on: 16 May 2013

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Article

Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells

Rachel M. Hagen, Veronica S. Chedea, Christopher P. Mintoff, Elizabeth Bowler, H. Ruth Morse, Michael R. Ladomery
Pages: 194-200
Published online on: 24 April 2013

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Article

Induction of apoptosis and suppression of angiogenesis of hepatocellular carcinoma by HS-159, a novel phosphatidylinositol 3-kinase inhibitor

Sun-Mi Yun, Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Soyoung Lee, Sungwoo Hong, Soon-Sun Hong
Pages: 201-209
Published online on: 22 April 2013

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Article

Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan Corrigendum in /10.3892/ijo.2026.5868

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Pages: 210-218
Published online on: 08 May 2013

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Article

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma

Tadashi Ashizawa, Haruo Miyata, Akira Iizuka, Masaru Komiyama, Chie Oshita, Akiko Kume, Masahiro Nogami, Mika Yagoto, Ichiro Ito, Takuma Oishi, Reiko Watanabe, Koichi Mitsuya, Kenji Matsuno, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Akira Asai, Yoko Nakasu, Ken Yamaguchi, Yasuto Akiyama
Pages: 219-227
Published online on: 23 April 2013

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Article

The role of a ginseng saponin metabolite as a DNA methyltransferase inhibitor in colorectal cancer cells

Kyoung Ah Kang, Hee Sun Kim, Dong Hyun Kim, Jin Won Hyun
Pages: 228-236
Published online on: 02 May 2013

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Article

Cloning, chromosomal characterization and FISH mapping of the NAD+-dependent histone deacetylase gene sirtuin 5 in the mouse

Susanne Voelter-Mahlknecht, Ulrich Mahlknecht
Pages: 237-245
Published online on: 14 May 2013

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Article

Characterization of ZC3H15 as a potential TRAF-2-interacting protein implicated in the NFκB pathway and overexpressed in AML

Gianni Capalbo, Thea Mueller-Kuller, Steffen Koschmieder, Hans-Ulrich Klein, Oliver G. Ottmann, Dieter Hoelzer, Urban J. Scheuring
Pages: 246-254
Published online on: 29 April 2013

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Article

Generation and characterization of rabbit polyclonal antibodies against Vasohibin-2 for determination of its intracellular localization

Jie Sun, Min Tu, Bei Han, Xiaofeng Xue, Ye Zhang, Jishu Wei, Jianmin Chen, Zipeng Lu, Yong An, Baobao Cai, Nan Lv, Kuirong Jiang, Yi Miao, Wentao Gao
Pages: 255-261
Published online on: 24 April 2013

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Article

Synergistic induction of apoptosis by sulindac and simvastatin in A549 human lung cancer cells via reactive oxygen species-dependent mitochondrial dysfunction

Ki-Eun Hwang, Chul Park, Su-Jin Kwon, Young-Suk Kim, Do-Sim Park, Mi-Kyung Lee, Byoung-Ryun Kim, Seong-Hoon Park, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 262-270
Published online on: 09 May 2013

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Article

Efficacy of schedule-dependent metronomic S-1 chemotherapy in human oral squamous cell carcinoma cells

Tarannum Ferdous, Koji Harada, Takanori Kin, Toyoko Harada, Yoshiya Ueyama
Pages: 271-279
Published online on: 20 May 2013

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Article

Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients

Mouldy Sioud, Stein Sæbøe-Larssen, Thea Eline Hetland, Janne Kærn, Anne Mobergslien, Gunnar Kvalheim
Pages: 280-288
Published online on: 25 April 2013

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Article

Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells

Zhiyu Zhang, Chong-Zhi Wang, Guang-Jian Du, Lian-Wen Qi, Tyler Calway, Tong-Chuan He, Wei Du, Chun-Su Yuan
Pages: 289-296
Published online on: 17 May 2013

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Article

Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms

Federica Ruffini, Stefania D'Atri, Pedro M. Lacal
Pages: 297-306
Published online on: 20 May 2013

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Article

MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer

Berlinda Verdoodt, Matthias Neid, Markus Vogt, Viktoria Kuhn, Sven-Thorsten Liffers, Rein-Jüri Palisaar, Joachim Noldus, Andrea Tannapfel, Alireza Mirmohammadsadegh
Pages: 307-314
Published online on: 23 April 2013

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Article

Xylitol inhibits in vitro and in vivo angiogenesis by suppressing the NF-κB and Akt signaling pathways

Eui-Yeun Yi, Yung-Jin Kim
Pages: 315-320
Published online on: 24 April 2013

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Article

Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling

Xiaolong Wang, Ning Zhang, Qiang Huo, Mingjuan Sun, Shangge Lv, Qifeng Yang
Pages: 321-328
Published online on: 20 May 2013

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Article

Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation

Kriengsak Lirdprapamongkol, Hiroaki Sakurai, Sherif Abdelhamed, Satoru Yokoyama, Sirivan Athikomkulchai, Amornrat Viriyaroj, Suresh Awale, Somsak Ruchirawat, Jisnuson Svasti, Ikuo Saiki
Pages: 329-337
Published online on: 01 May 2013

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Article

Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells

Chin-Mu Hsu, Yuhsin Tsai, Lei Wan, Fuu-Jen Tsai
Pages: 338-348
Published online on: 16 May 2013

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Journal Cover
October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

MicroRNA regulation of macrophage polarization in lung cancer: Regulatory networks and therapeutic potential (Review)

Zhao Yiming, Li Jie
Article Number: 121
Published online on: 02 September 2026

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Article Open Access

Effect of xeroderma pigmentosum group C on the characteristics and regulatory mechanisms of lung cancer stem cells

Ben Yang, Yang Yang, Weiyu Wang, Yubing Wang, Huaijie Wang, Liya Qin, Yongming Wang, Sipeng Sun, Shubo Wang, Meihua Qu
Article Number: 120
Published online on: 01 September 2026

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Review Open Access

Post‑translational modification‑governed immune states in cancer immunity: Biomarker implications for checkpoint competence, tumor visibility and immunotherapy resistance (Review)

Jinghao Pan, Boyang Li, Ruonan Lin, Chenlu Fang, Lucy Yue Lau, Zehao Hong, Yi Chen
Article Number: 119
Published online on: 21 August 2026

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Correction Open Access

[Corrigendum] Sulforaphane reduces molecular response to hypoxia in ovarian tumor cells independently of their resistance to chemotherapy

Michal Pastorek, Veronika Simko, Martina Takacova, Monika Barathova, Maria Bartosova, Luba Hunakova, Olga Sedlakova, Sona Hudecova, Olga Krizanova, Franck Dequiedt, Silvia Pastorekova, Jan Sedlak
Article Number: 118
Published online on: 20 August 2026

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Article Open Access

Single in situ intratumoral low‑dose shikonin hydrogel plus mild photothermal therapy elicits systemic antitumor immunity in immune‑cold triple‑negative breast cancer

Tao Pan, Zujian Feng, Ting Shang, Jun Jiang, Fang Zhang
Article Number: 117
Published online on: 19 August 2026

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Article Open Access

KIAA1429 knockdown alleviates osteosarcoma  progression by destabilizing SLC7A11 mRNA via m6A methylation to promote ferroptosis

Hui Zeng, Yunyan Zhong, Dingbiao Zeng, Shiliang Xiao, Song Zou
Article Number: 116
Published online on: 17 August 2026

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Correction Open Access

[Corrigendum] Tanshinone I effectively induces apoptosis in estrogen receptor‑positive (MCF‑7) and estrogen receptor‑negative (MDA‑MB‑231) breast cancer cells

Irina Tsoy Nizamutdinova, Gyeong Won Lee, Kun Ho Son, Su Jin Jeon, Sam Sik Kang, Yeong Shik Kim, Jae Heun Lee, Han Geuk Seo, Ki Churl Chang, Hye Jung Kim
Article Number: 115
Published online on: 12 August 2026

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Review Open Access

Signaling pathways and targeted therapy in high‑risk refractory thyroid cancer: From bench to bedside (Review)

Jian Wang, Zhi Liu, Qing Zhang, Wei Sun
Article Number: 114
Published online on: 11 August 2026

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Retraction Open Access

[Retracted] Downmodulation of dimethyl transferase activity enhances tumor necrosis factor‑related apoptosis‑inducing ligand‑ induced apoptosis in prostate cancer cells

Claudio Festuccia, Giovanni Luca Gravina, Anna Maria D'Alessandro, Danilo Millimaggi, Cristiana Di Rocco, Vincenza Dolo, Enrico Ricevuto, Carlo Vicentini, Mauro Bologna
Article Number: 113
Published online on: 10 August 2026

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Review Open Access

The pivotal role of SCD1 in digestive cancers: Bridging lipid metabolic reprogramming and programmed cell death (Review)

Yangxi Fu, Zheng Wang, Lin Liu, Xudong Tang
Article Number: 112
Published online on: 07 August 2026

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Article Open Access

piR‑164552 promotes malignant progression in head and neck squamous cell carcinoma via the RBM4/EIF4E2 signaling axis: Insights from multi‑omics and functional analyses

Shan Yang, Zhen Shang, Shunxian Xia, Hongbo Liu, Yanhan Dong, Xiaomin Wang, Wenhua Xu, Haijun Lu
Article Number: 111
Published online on: 07 August 2026

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Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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Journal Cover
November-2026 Volume 69 Issue 5

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] TIP60 governs the auto‑ubiquitination of UHRF1 through USP7 dissociation from the UHRF1/USP7 complex

Tanveer Ahmad, Waseem Ashraf, Abdulkhaleg Ibrahim, Liliyana Zaayter, Christian D. Muller, Ali Hamiche, Yves Mély, Christian Bronner, Marc Mousli
Article Number: 125
Published online on: 14 September 2026

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Correction Open Access

[Corrigendum] miR‑221/222 promote malignant progression of glioma through activation of the Akt pathway

Junxia Zhang, Lei Han, Youlin Ge, Xuan Zhou, Anling Zhang, Chunzhi Zhang, Yue Zhong, Yongping You, Peiyu Pu, Chunsheng Kang
Article Number: 124
Published online on: 03 September 2026

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Review Open Access

Dendritic cell‑based vaccines for colorectal cancer: Mechanisms, clinical progress and future directions (Review)

Lian Yih Pong, Siti Ayuni Hassanudin, Seng Kong Tham, Ravichandran Manickam, Chee Yin Wong, Keat Seong Poh, Chit Laa Poh
Article Number: 123
Published online on: 03 September 2026

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Retraction Open Access

[Retracted] Pro‑metastatic intracellular signaling of the elaidic trans fatty acid

Kiyomu Fujii, Yi Luo, Rina Fujiwara-tani, Shingo Kishi, Song He, Shuyun Yang, Takamitsu Sasaki, Hitoshi Ohmori, Hiroki Kuniyasu
Article Number: 122
Published online on: 02 September 2026

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