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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
July 2013 Volume 43 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

The role of tumor-associated macrophages in breast cancer progression (Review)

Elias Obeid, Rita Nanda, Yang-Xin Fu, Olufunmilayo I. Olopade
Pages: 5-12
Published online on: 14 May 2013

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Article Open Access

Analyses of the combination of 6-MP and dasatinib in cell culture

Gurmeet Kaur, Holger Behrsing, Ralph E. Parchment, Myrtle Davis Millin, Beverly A. Teicher
Pages: 13-22
Published online on: 02 May 2013

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Article Open Access

Trabectedin in metastatic soft tissue sarcomas: Role of pretreatment and age

Mathias Hoiczyk, Florian Grabellus, Lars Podleska, Marit Ahrens, Benjamin Schwindenhammer, Georg Taeger, Christoph Pöttgen, Martin Schuler, Sebastian Bauer
Pages: 23-28
Published online on: 02 May 2013

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Article Open Access

ROS and ERK1/2-mediated caspase-9 activation increases XAF1 expression in dexamethasone-induced apoptosis of EBV-transformed B cells

Ga Bin Park, Yunock Choi, Yeong Seok Kim, Hyun-Kyung Lee, Daejin Kim, Dae Young Hur
Pages: 29-38
Published online on: 20 May 2013

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in adult human sarcoma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 39-49
Published online on: 09 May 2013

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Article Open Access

Glioma-amplified sequence KUB3 influences double-strand break repair after ionizing radiation

Ulrike Fischer, Stefanie Rheinheimer, Andrea Krempler, Markus Löbrich, Eckart Meese
Pages: 50-56
Published online on: 13 May 2013

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Article

Identification of APN/CD13 as the target antigen of FU3, a human monoclonal antibody that recognizes malignant fibrous histiocytoma

Mikiko Aoki, Kazuki Nabeshima, Hiroyuki Hayashi, Makoto Hamasaki, Hiroshi Iwasaki
Pages: 57-62
Published online on: 16 May 2013

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Article

Loss of HOXD10 expression induced by upregulation of miR-10b accelerates the migration and invasion activities of ovarian cancer cells

Ikue Nakayama, Masahiko Shibazaki, Akiko Yashima-Abo, Fumiharu Miura, Toru Sugiyama, Tomoyuki Masuda, Chihaya Maesawa
Pages: 63-71
Published online on: 13 May 2013

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Article

Prx1 modulates the chemosensitivity of lung cancer to docetaxel through suppression of FOXO1-induced apoptosis

Ki-Eun Hwang, Do-Sim Park, Young-Suk Kim, Byoung-Ryun Kim, Seong-Nam Park, Mi-Kyung Lee, Seong-Hoon Park, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 72-78
Published online on: 24 April 2013

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Article

Effect of a novel bladder preservation therapy, BOAI-CDDP-radiation (OMC-regimen)

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Hayahito Nomi, Hiroshi Uehara, Kazumasa Komura, Koichiro Minami, Junko Kouno, Yatsugu Kotake, Hirokazu Abe, Shizuko Takagi, Kazuhiro Yamamoto, Yoshihumi Narumi, Satoshi Kiyama
Pages: 79-87
Published online on: 26 April 2013

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Article

Estrogen receptor 1 gene as a tumor suppressor gene in hepatocellular carcinoma detected by triple-combination array analysis

Mitsuhiro Hishida, Shuji Nomoto, Yoshikuni Inokawa, Masamichi Hayashi, Mitsuro Kanda, Yukiyasu Okamura, Yoko Nishikawa, Chie Tanaka, Daisuke Kobayashi, Suguru Yamada, Goro Nakayama, Tsutomu Fujii, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Shin Takeda, Yasuhiro Kodera
Pages: 88-94
Published online on: 20 May 2013

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Article

Sphere-forming cell subsets with cancer stem cell properties in human musculoskeletal sarcomas

Manuela Salerno, Sofia Avnet, Gloria Bonuccelli, Adriana Eramo, Ruggero De Maria, Marco Gambarotti, Gabriella Gamberi, Nicola Baldini
Pages: 95-102
Published online on: 01 May 2013

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Article

Primary resistance phenomena to oncolytic measles vaccine viruses

Markus Noll, Susanne Berchtold, Johanna Lampe, Nisar P. Malek, Michael Bitzer, Ulrich M. Lauer
Pages: 103-112
Published online on: 23 April 2013

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Article

Epithelial-mesenchymal transition triggers cancer stem cell generation in human thyroid cancer cells

Ling Lan, Yong Luo, Dai Cui, Bing-Yin Shi, Wei Deng, Li-Li Huo, Hai-Ling Chen, Guo-Ying Zhang, Li-Li Deng
Pages: 113-120
Published online on: 22 April 2013

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Article

Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells

Patrizia Portanova, Antonietta Notaro, Ornella Pellerito, Selenia Sabella, Michela Giuliano, Giuseppe Calvaruso
Pages: 121-130
Published online on: 17 May 2013

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Article

Hypoxia promotes radioresistance of CD133-positive Hep-2 human laryngeal squamous carcinoma cells in vitro

Maoxin Wang, Xiaoming Li, Yongtao Qu, Ou Xu, Qingjia Sun
Pages: 131-140
Published online on: 02 May 2013

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Article

Dual inhibition of EGFR and c-Met kinase activation by MJ-56 reduces metastasis of HT29 human colorectal cancer cells

Hui-Jye Chen, Yi-Lin Jiang, Chung-Ming Lin, Shih-Chang Tsai, Shu-Fen Peng, Shinji Fushiya, Mann-Jen Hour, Jai-Sing Yang
Pages: 141-150
Published online on: 16 May 2013

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Article

Enhancing HSP70-ShRNA transfection in 22RV1 prostate cancer cells by combination of sonoporation, liposomes and HTERT/CMV chimeric promoter

Yun Hua Li, Li Fang Jin, Lian-Fang Du, Qiu Sheng Shi, Long Liu, Xiao Jia, Ying Wu, Fan Li, Hang Hui Wang
Pages: 151-158
Published online on: 25 April 2013

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Article

RNA interference-mediated knockdown of Livin suppresses cell proliferation and invasion and enhances the chemosensitivity to cisplatin in human osteosarcoma cells

Xu Li, Shuli Fan, Leiming Li, Liguo Wang, Guangyu Fan, Qun Zhao, Yan Li
Pages: 159-168
Published online on: 30 April 2013

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Article

Insertional activation of myb by F-MuLV in SCID mice induces myeloid leukemia

Mehran Haeri, Youjun Li, Yanmei Li, Qi Li, David E. Spaner, Yaacov Ben-David
Pages: 169-176
Published online on: 16 May 2013

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Article

Study on molecular imaging and radionuclide therapy of human nasopharyngeal carcinoma cells transfected with baculovirus-mediated sodium/iodine symporter gene

Jianzhang Wang, Shuai Liu, Jun Wang, Yifan Zhang, Biao Li, Changping Cai, Shili Wang
Pages: 177-184
Published online on: 13 May 2013

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Article

Pharmacological inhibition of macrophage migration inhibitory factor interferes with the proliferation and invasiveness of squamous carcinoma cells

Nadège Kindt, Guy Laurent, Denis Nonclercq, Fabrice Journé, Ghanem Ghanem, Hugues Duvillier, Hans-Joachim Gabius, Jérôme Lechien, Sven Saussez
Pages: 185-193
Published online on: 16 May 2013

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Article

Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells

Rachel M. Hagen, Veronica S. Chedea, Christopher P. Mintoff, Elizabeth Bowler, H. Ruth Morse, Michael R. Ladomery
Pages: 194-200
Published online on: 24 April 2013

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Article

Induction of apoptosis and suppression of angiogenesis of hepatocellular carcinoma by HS-159, a novel phosphatidylinositol 3-kinase inhibitor

Sun-Mi Yun, Ju-Hee Lee, Kyung Hee Jung, Hyunseung Lee, Soyoung Lee, Sungwoo Hong, Soon-Sun Hong
Pages: 201-209
Published online on: 22 April 2013

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Article

Influence of MLH1 on colon cancer sensitivity to poly(ADP-ribose) polymerase inhibitor combined with irinotecan

Lucio Tentori, Carlo Leonetti, Alessia Muzi, Annalisa Susanna Dorio, Manuela Porru, Susanna Dolci, Federica Campolo, Patrizia Vernole, Pedro Miguel Lacal, Françoise Praz, Grazia Graziani
Pages: 210-218
Published online on: 08 May 2013

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Article

Effect of the STAT3 inhibitor STX-0119 on the proliferation of cancer stem-like cells derived from recurrent glioblastoma

Tadashi Ashizawa, Haruo Miyata, Akira Iizuka, Masaru Komiyama, Chie Oshita, Akiko Kume, Masahiro Nogami, Mika Yagoto, Ichiro Ito, Takuma Oishi, Reiko Watanabe, Koichi Mitsuya, Kenji Matsuno, Toshio Furuya, Tadashi Okawara, Masami Otsuka, Naohisa Ogo, Akira Asai, Yoko Nakasu, Ken Yamaguchi, Yasuto Akiyama
Pages: 219-227
Published online on: 23 April 2013

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Article

The role of a ginseng saponin metabolite as a DNA methyltransferase inhibitor in colorectal cancer cells

Kyoung Ah Kang, Hee Sun Kim, Dong Hyun Kim, Jin Won Hyun
Pages: 228-236
Published online on: 02 May 2013

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Article

Cloning, chromosomal characterization and FISH mapping of the NAD+-dependent histone deacetylase gene sirtuin 5 in the mouse

Susanne Voelter-Mahlknecht, Ulrich Mahlknecht
Pages: 237-245
Published online on: 14 May 2013

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Article

Characterization of ZC3H15 as a potential TRAF-2-interacting protein implicated in the NFκB pathway and overexpressed in AML

Gianni Capalbo, Thea Mueller-Kuller, Steffen Koschmieder, Hans-Ulrich Klein, Oliver G. Ottmann, Dieter Hoelzer, Urban J. Scheuring
Pages: 246-254
Published online on: 29 April 2013

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Article

Generation and characterization of rabbit polyclonal antibodies against Vasohibin-2 for determination of its intracellular localization

Jie Sun, Min Tu, Bei Han, Xiaofeng Xue, Ye Zhang, Jishu Wei, Jianmin Chen, Zipeng Lu, Yong An, Baobao Cai, Nan Lv, Kuirong Jiang, Yi Miao, Wentao Gao
Pages: 255-261
Published online on: 24 April 2013

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Article

Synergistic induction of apoptosis by sulindac and simvastatin in A549 human lung cancer cells via reactive oxygen species-dependent mitochondrial dysfunction

Ki-Eun Hwang, Chul Park, Su-Jin Kwon, Young-Suk Kim, Do-Sim Park, Mi-Kyung Lee, Byoung-Ryun Kim, Seong-Hoon Park, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 262-270
Published online on: 09 May 2013

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Article

Efficacy of schedule-dependent metronomic S-1 chemotherapy in human oral squamous cell carcinoma cells

Tarannum Ferdous, Koji Harada, Takanori Kin, Toyoko Harada, Yoshiya Ueyama
Pages: 271-279
Published online on: 20 May 2013

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Article

Silencing of indoleamine 2,3-dioxygenase enhances dendritic cell immunogenicity and antitumour immunity in cancer patients

Mouldy Sioud, Stein Sæbøe-Larssen, Thea Eline Hetland, Janne Kærn, Anne Mobergslien, Gunnar Kvalheim
Pages: 280-288
Published online on: 25 April 2013

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Article

Genistein induces G2/M cell cycle arrest and apoptosis via ATM/p53-dependent pathway in human colon cancer cells

Zhiyu Zhang, Chong-Zhi Wang, Guang-Jian Du, Lian-Wen Qi, Tyler Calway, Tong-Chuan He, Wei Du, Chun-Su Yuan
Pages: 289-296
Published online on: 17 May 2013

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Article

Neuropilin-1 expression promotes invasiveness of melanoma cells through vascular endothelial growth factor receptor-2-dependent and -independent mechanisms

Federica Ruffini, Stefania D'Atri, Pedro M. Lacal
Pages: 297-306
Published online on: 20 May 2013

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Article

MicroRNA-205, a novel regulator of the anti-apoptotic protein Bcl2, is downregulated in prostate cancer

Berlinda Verdoodt, Matthias Neid, Markus Vogt, Viktoria Kuhn, Sven-Thorsten Liffers, Rein-Jüri Palisaar, Joachim Noldus, Andrea Tannapfel, Alireza Mirmohammadsadegh
Pages: 307-314
Published online on: 23 April 2013

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Article

Xylitol inhibits in vitro and in vivo angiogenesis by suppressing the NF-κB and Akt signaling pathways

Eui-Yeun Yi, Yung-Jin Kim
Pages: 315-320
Published online on: 24 April 2013

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Article

Huaier aqueous extract suppresses human breast cancer cell proliferation through inhibition of estrogen receptor α signaling

Xiaolong Wang, Ning Zhang, Qiang Huo, Mingjuan Sun, Shangge Lv, Qifeng Yang
Pages: 321-328
Published online on: 20 May 2013

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Article

Chrysin overcomes TRAIL resistance of cancer cells through Mcl-1 downregulation by inhibiting STAT3 phosphorylation

Kriengsak Lirdprapamongkol, Hiroaki Sakurai, Sherif Abdelhamed, Satoru Yokoyama, Sirivan Athikomkulchai, Amornrat Viriyaroj, Suresh Awale, Somsak Ruchirawat, Jisnuson Svasti, Ikuo Saiki
Pages: 329-337
Published online on: 01 May 2013

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Article

Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells

Chin-Mu Hsu, Yuhsin Tsai, Lei Wan, Fuu-Jen Tsai
Pages: 338-348
Published online on: 16 May 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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