|
1.
|
Friedberg EC: DNA damage and repair.
Nature. 421:436–440. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
2.
|
Beard WA and Wilson SH: Structure and
mechanism of DNA polymerase β. Chem Rev. 106:361–382. 2006.
|
|
3.
|
Kidane D, Jonason AS, Gorton TS, Mihaylov
I, Pan J, Keeney S, de Rooij DG, Ashley T, Keh A, Liu Y, Banerjee
U, Zelterman D and Sweasy JB: DNA polymerase β is critical for
mouse meiotic synapsis. EMBO J. 29:410–423. 2010.
|
|
4.
|
Wilson TE and Lieber MR: Efficient
processing of DNA ends during yeast nonhomologous end joining:
evidence for a DNA polymerase β (POL4)-dependent pathway. J Biol
Chem. 274:23599–23609. 1999.PubMed/NCBI
|
|
5.
|
Horton JK, Srivastava DK, Zmudzka BZ and
Wilson SH: Strategic down-regulation of DNA polymerase β by
antisense RNA sensitizes mammalian cells to specific DNA damaging
agents. Nucleic Acids Res. 23:3810–3815. 1995.
|
|
6.
|
Oda N, Saxena JK, Jenkins TM, Prasad R,
Wilson SH and Ackerman EJ: DNA polymerases α and β are required for
DNA repair in an efficient nuclear extract from Xenopus
oocytes. J Biol Chem. 271:13816–13820. 1996.
|
|
7.
|
Jenkins TM, Saxena JK, Kumar A, Wilson SH
and Ackerman EJ: DNA polymerase β and DNA synthesis in
Xenopus oocytes and in a nuclear extract. Science.
258:475–478. 1992.
|
|
8.
|
Sugo N, Aratani Y, Nagashima Y, Kubota Y
and Koyama H: Neonatal lethality with abnormal neurogenesis in mice
deficient in DNA polymerase β. EMBO J. 19:1397–1404.
2000.PubMed/NCBI
|
|
9.
|
Tanabe K, Bohn EW and Wilson SH:
Steady-state kinetics of mouse DNA polymerase β. Biochemistry.
18:3401–3406. 1979.
|
|
10.
|
Beard WA, Shock DD, Yang XP, DeLauder SF
and Wilson SH: Loss of DNA polymerase β stacking interactions with
templating purines, but not pyrimidines, alters catalytic
efficiency and fidelity. J Biol Chem. 277:8235–8242. 2002.
|
|
11.
|
Ollis DL, Brick P, Hamlin R, Xuong NG and
Steitz TA: Structure of large fragment of Escherichia coli
DNA polymerase I complexed with dTMP. Nature. 313:762–766.
1985.PubMed/NCBI
|
|
12.
|
Pelletier H, Sawaya MR, Wolfle W, Wilson
SH and Kraut J: Crystal structures of human DNA polymerase β
complexed with DNA: implications for catalytic mechanism,
processivity, and fidelity. Biochemistry. 35:12742–12761. 1996.
|
|
13.
|
Sawaya MR, Prasad R, Wilson SH, Kraut J
and Pelletier H: Crystal structures of human DNA polymerase β
complexed with gapped and nicked DNA: evidence for an induced fit
mechanism. Biochemistry. 36:11205–11215. 1997.
|
|
14.
|
Starcevic D, Dalal S and Sweasy JB: Is
there a link between DNA polymerase β and cancer? Cell Cycle.
3:998–1001. 2004.
|
|
15.
|
Lang T, Maitra M, Starcevic D, Li SX and
Sweasy JB: A DNA polymerase β mutant from colon cancer cells
induces mutations. Proc Natl Acad Sci USA. 101:6074–6079. 2004.
|
|
16.
|
Lang T, Dalal S, Chikova A, DiMaio D and
Sweasy JB: The E295K DNA polymerase beta gastric cancer-associated
variant interferes with base excision repair and induces cellular
transformation. Mol Cell Biol. 27:5587–5596. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
17.
|
Sweasy JB, Lang T, Starcevic D, Sun KW,
Lai CC, Dimaio D and Dalal S: Expression of DNA polymerase β
cancer-associated variants in mouse cells results in cellular
transformation. Proc Natl Acad Sci USA. 102:14350–14355. 2005.
|
|
18.
|
Makridakis NM, Caldas Ferraz LF and
Reichardt JK: Genomic analysis of cancer tissue reveals that
somatic mutations commonly occur in a specific motif. Hum Mutat.
30:39–48. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19.
|
An CL, Chen D and Makridakis NM:
Systematic biochemical analysis of somatic missense mutations in
DNA polymerase β found in prostate cancer reveal alteration of
enzymatic function. Hum Mutat. 32:415–423. 2011.PubMed/NCBI
|
|
20.
|
Batra VK, Beard WA, Shock DD, Krahn JM,
Pedersen LC and Wilson SH: Magnesium induced assembly of a complete
DNA polymerase catalytic complex. Structure (Camb). 14:757–766.
2006. View Article : Google Scholar : PubMed/NCBI
|
|
21.
|
Dalal S, Hile S, Eckert KA, Sun KW,
Starcevic D and Sweasy JB: Prostate-cancer-associated I260M variant
of DNA polymerase β is a sequence-specific mutator. Biochemistry.
44:15664–15673. 2005.PubMed/NCBI
|
|
22.
|
An CL, Lim WJ, Hong SY, Kim EJ, Shin EC,
Kim MK, Lee JR, Park SR, Woo JG, Lim YP and Yun HD: Analysis of bgl
operon structure and characterization of β-glucosidase from
Pectobacterium carotovorum subsp carotovorum LY34.
Biosci Biotechnol Biochem. 68:2270–2278. 2004.
|
|
23.
|
Kosa JL and Sweasy JB:
3′-Azido-3′-deoxythymidine-resistant mutants of DNA polymerase β
identified by in vivo selection. J Biol Chem. 274:3851–3858.
1999.
|
|
24.
|
Servant L, Cazaux C, Bieth A, Iwai S,
Hanaoka F and Hoffmann JS: A role for DNA polymerase β in mutagenic
UV lesion bypass. J Biol Chem. 277:50046–50053. 2002.
|
|
25.
|
Chagovetz AM, Sweasy JB and Preston BD:
Increased activity and fidelity of DNA polymerase β on
single-nucleotide gapped DNA. J Biol Chem. 272:27501–27504.
1997.
|
|
26.
|
Li SX, Vaccaro J and Sweasy JB:
Involvement of phenylalanine 272 of DNA polymerase beta in
discriminating between correct and incorrect deoxynucleoside
triphosphates. Biochemistry. 38:4800–4808. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
27.
|
Maitra M, Gudzelak A Jr, Li SX, Matsumoto
Y, Eckert KA, Jager J and Sweasy JB: Threonine 79 is a hinge
residue that governs the fidelity of DNA polymerase β by helping to
position the DNA within the active site. J Biol Chem.
277:35550–35560. 2002.PubMed/NCBI
|
|
28.
|
Beard WA, Bebenek K, Darden TA, Li L,
Prasad R, Kunkel TA and Wilson SH: Vertical-scanning mutagenesis of
a critical tryptophan in the minor groove binding track of HIV-1
reverse transcriptase. Molecular nature of polymerase-nucleic acid
interactions. J Biol Chem. 273:30435–30442. 1998. View Article : Google Scholar
|
|
29.
|
Beard WA, Batra VK and Wilson SH: DNA
polymerase structure-based insight on the mutagenic properties of
8-oxoguanine. Mutat Res. 703:18–23. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
30.
|
Beard WA, Osheroff WP, Prasad R, Sawaya
MR, Jaju M, Wood TG, Kraut J, Kunkel TA and Wilson SH: Enzyme-DNA
interactions required for efficient nucleotide incorporation and
discrimination in human DNA polymerase β. J Biol Chem.
271:12141–12144. 1996.PubMed/NCBI
|
|
31.
|
Beard WA, Shock DD, Vande Berg BJ and
Wilson SH: Efficiency of correct nucleotide insertion governs DNA
polymerase fidelity. J Biol Chem. 277:47393–47398. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
32.
|
Vande Berg BJ, Beard WA and Wilson SH: DNA
structure and aspartate 276 influence nucleotide binding to human
DNA polymerase β: implication for the identity of the rate-limiting
conformational change. J Biol Chem. 276:3408–3416. 2001.PubMed/NCBI
|
|
33.
|
Dalal S, Kosa JL and Sweasy JB: The D246V
mutant of DNA polymerase β misincorporates nucleotides: evidence
for a role for the flexible loop in DNA positioning within the
active site. J Biol Chem. 279:577–584. 2004.PubMed/NCBI
|
|
34.
|
Sobol RW, Watson DE, Nakamura J, Yakes FM,
Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR,
Samson LD and Wilson SH: Mutations associated with base excision
repair deficiency and methylation-induced genotoxic stress. Proc
Natl Acad Sci USA. 99:6860–6865. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
35.
|
Pettersen EF, Goddard TD, Huang CC, Couch
GS, Greenblatt DM, Meng EC and Ferrin TE: UCSF Chimera - a
visualization system for exploratory research and analysis. J
Comput Chem. 25:1605–1612. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
36.
|
Dunbrack RL Jr: Rotamer libraries in the
21st century. Curr Opin Struct Biol. 12:431–440. 2002. View Article : Google Scholar : PubMed/NCBI
|
