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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
October 2013 Volume 43 Issue 4

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Precancerous colorectal lesions (Review)

Vincenza Conteduca, Domenico Sansonno, Sabino Russi, Franco Dammacco
Pages: 973-984
Published online on: 29 July 2013

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Review Open Access

From microRNA functions to microRNA therapeutics: Novel targets and novel drugs in breast cancer research and treatment (Review)

Roberta Piva, Demetrios A. Spandidos, Roberto Gambari
Pages: 985-994
Published online on: 12 August 2013

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Review

A dynamic interplay between alternative polyadenylation and microRNA regulation: Implications for cancer (Review)

Jindan An, Xiaodong Zhu, Hongwei Wang, Xiudong Jin
Pages: 995-1001
Published online on: 01 August 2013

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Article Open Access

Apolipoprotein E gene polymorphism influences aggressive behavior in prostate cancer cells by deregulating cholesterol homeostasis

Godwin O. Ifere, Renee Desmond, Wendy Demark-Wahnefried, Tim R. Nagy
Pages: 1002-1010
Published online on: 07 August 2013

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Article Open Access

Plasma endothelial protein C receptor influences innate immune response in ovarian cancer by decreasing the population of natural killer and TH17 helper cells

Dalel Azzazene, Hamda Al Thawadi, Halema Al Farsi, Samaher Besbes, Caroline Geyl, Shahsoltan Mirshahi, Julia Pardo, Anne Marie Faussat, Soria Jeannette, Amu Therwath, Eric Pujade-Lauraine, Massoud Mirshahi
Pages: 1011-1018
Published online on: 18 July 2013

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Article Open Access

Analysis of cytotoxic T lymphocytes from a patient with hepatocellular carcinoma who showed a clinical response to vaccination with a glypican‑3‑derived peptide

Yoshitaka Tada, Toshiaki Yoshikawa, Manami Shimomura, Yu Sawada, Mayuko Sakai, Hirofumi Shirakawa, Daisuke Nobuoka, Tetsuya Nakatsura
Pages: 1019-1026
Published online on: 31 July 2013

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Article Open Access

Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines

M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 1027-1035
Published online on: 23 July 2013

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Article Open Access

Pooled analysis of case-control studies on acoustic neuroma diagnosed 1997-2003 and 2007-2009 and use of mobile and cordless phones

Lennart Hardell, Michael Carlberg, Fredrik Söderqvist, Kjell Hansson Mild
Pages: 1036-1044
Published online on: 22 July 2013

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Article Open Access

Detection of EGFR gene mutations in non-small cell lung cancer: Lessons from a single-institution routine analysis of 1,403 tumor samples

Audrey Vallee, Christine Sagan, Anne-Gaelle Le Loupp, Kalyane Bach, Thomas Dejoie, Marc G. Denis
Pages: 1045-1051
Published online on: 07 August 2013

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Article Open Access

Regulation of Id1 expression by epigallocatechin‑3‑gallate and its effect on the proliferation and apoptosis of poorly differentiated AGS gastric cancer cells

Jun Ma, Min Shi, Guangming Li, Na Wang, Jue Wei, Ting Wang, Jiali Ma, Yugang Wang
Pages: 1052-1058
Published online on: 30 July 2013

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Article Open Access

Capsosiphon fulvescens glycoprotein reduces AGS gastric cancer cell migration by downregulating transforming growth factor-β1 and integrin expression

Young-Min Kim, In-Hye Kim, Taek-Jeong Nam
Pages: 1059-1065
Published online on: 07 August 2013

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Article

MicroRNA-29a induces resistance to gemcitabine through the Wnt/β-catenin signaling pathway in pancreatic cancer cells

Hiroaki Nagano, Yoshito Tomimaru, Hidetoshi Eguchi, Naoki Hama, Hiroshi Wada, Koichi Kawamoto, Shogo Kobayashi, Masaki Mori, Yuichiro Doki
Pages: 1066-1072
Published online on: 24 July 2013

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Article

Elevated expression of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 in primary sclerosing cholangitis: Ιmplications for cholangiocarcinogenesis

Yasutaka Ishii, Tamito Sasaki, Masahiro Serikawa, Tomoyuki Minami, Akihito Okazaki, Masanobu Yukutake, Takashi Ishigaki, Keiichi Kosaka, Teruo Mouri, Satoshi Yoshimi, Akinori Shimizu, Tomofumi Tsuboi, Kazuaki Chayama
Pages: 1073-1079
Published online on: 24 July 2013

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Article

A novel HDAC inhibitor OBP-801 and a PI3K inhibitor LY294002 synergistically induce apoptosis via the suppression of survivin and XIAP in renal cell carcinoma

Takeshi Yamada, Mano Horinaka, Masahide Shinnoh, Takashi Yoshioka, Tsuneharu Miki, Toshiyuki Sakai
Pages: 1080-1086
Published online on: 30 July 2013

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Article

A great option for elderly patients with locally invasive bladder cancer, BOAI-CDDP-radiation (OMC regimen)

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Hayahito Nomi, Hajime Hirano, Hiroshi Uehara, Kazumasa Komura, Koichiro Minami, Junko Kouno, Yatsugu Kotake, Hirokazu Abe, Shizuko Takagi, Naokazu Ibuki, Kazuhiro Yamamoto, Yoshihumi Narumi, Satoshi Kiyama
Pages: 1087-1094
Published online on: 08 August 2013

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Article

Bone formation induced by BMP-2 in human osteosarcoma cells

Lin Wang, Paul Park, Frank La Marca, Khoi Than, Shayan Rahman, Chia-Ying Lin
Pages: 1095-1102
Published online on: 23 July 2013

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Article

Anti-proliferative effect of honokiol in oral squamous cancer through the regulation of specificity protein 1

Dong-Wook Kim, Seon Mi Ko, Young-Joo Jeon, Young-Woock Noh, Nag-Jin Choi, Sung-Dae Cho, Hong Seop Moon, Young Sik Cho, Jae-Chen Shin, Seon-Min Park, Kang Seok Seo, Ji-Young Choi, Jung-Il Chae, Jung-Hyun Shim
Pages: 1103-1110
Published online on: 22 July 2013

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Article

Cancer upregulated gene 2, a novel oncogene, enhances migration and drug resistance of colon cancer cells via STAT1 activation

Waraporn Malilas, Sang Seok Koh, Seokho Kim, Ratakorn Srisuttee, Il-Rae Cho, Jeong Moon, Hwa-Seung Yoo, Sangtaek Oh, Randal N. Johnston, Young-Hwa Chung
Pages: 1111-1116
Published online on: 05 August 2013

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Article

Inhibitory effects of a major soy isoflavone, genistein, on human DNA topoisomerase II activity and cancer cell proliferation

Yoshiyuki Mizushina, Kazuaki Shiomi, Isoko Kuriyama, Yoshihiro Takahashi, Hiromi Yoshida
Pages: 1117-1124
Published online on: 23 July 2013

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Article

From AR to c-Met: Androgen deprivation leads to a signaling pathway switch in prostate cancer cells

Tiancheng Liu, Desiree E. Mendes, Clifford E. Berkman
Pages: 1125-1130
Published online on: 18 July 2013

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Article

Understanding the loss-of-function in a triple missense mutant of DNA polymerase β found in prostate cancer

Changlong An, William A. Beard, Desheng Chen, Samuel H. Wilson, Nick M. Makridakis
Pages: 1131-1140
Published online on: 19 July 2013

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Article

Curcumin-loaded nanoparticles induce apoptotic cell death through regulation of the function of MDR1 and reactive oxygen species in cisplatin-resistant CAR human oral cancer cells

Pei-Ying Chang, Shu-Fen Peng, Chao-Ying Lee, Chi-Cheng Lu, Shih-Chang Tsai, Tzong-Ming Shieh, Tian-Shung Wu, Ming-Gene Tu, Michael Yuanchien Chen, Jai-Sing Yang
Pages: 1141-1150
Published online on: 05 August 2013

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Article

Enhanced immunotherapeutic effect of modified HPV16 E7-pulsed dendritic cell vaccine by an adeno-shRNA-SOCS1 virus

Yongqiang Zhu, Yi Zheng, Lin Mei, Mengqiong Liu, Shanshan Li, Huawei Xiao, Huijun Zhu, Shu Wu, Hongbo Chen, Laiqiang Huang
Pages: 1151-1159
Published online on: 22 July 2013

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Article

Novel methylsulfonyl chalcones as potential antiproliferative drugs for human prostate cancer: Involvement of the intrinsic pathway of apoptosis

Bassel Ismail, Lamia Ghezali, Rokhaya Gueye, Youness Limami, Christelle Pouget, David Y. Leger, Frederique Martin, Jean-Louis Beneytout, Jean-Luc Duroux, Mona Diab-Assaf, Catherine Fagnere, Bertrand Liagre
Pages: 1160-1168
Published online on: 19 July 2013

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Article

Triptolide induces apoptosis of PMA-treated THP-1 cells through activation of caspases, inhibition of NF-κB and activation of MAPKs

Seung-Won Park, Young Il Kim
Pages: 1169-1175
Published online on: 23 July 2013

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Article

Anticancer effects of marine carotenoids, fucoxanthin and its deacetylated product, fucoxanthinol, on osteosarcoma

Takayoshi Rokkaku, Ryuichiro Kimura, Chie Ishikawa, Takeshi Yasumoto, Masachika Senba, Fuminori Kanaya, Naoki Mori
Pages: 1176-1186
Published online on: 15 July 2013

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Article

Crosstalk between p38 and Smad3 through TGF-β1 in JEG-3 choriocarcinoma cells

Qian Xu, Yusi Tan, Kongyan Zhang, Yuhong Li
Pages: 1187-1193
Published online on: 22 July 2013

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Article

Follicle-stimulating hormone inhibits apoptosis in ovarian cancer cells by regulating the OCT4 stem cell signaling pathway

Zhenbo Zhang, Yaping Zhu, Yunli Lai, Xiaomei Wu, Zhengzhong Feng, Yinhua Yu, Robert C. Bast, Xiaoping Wan, Xiaowei Xi, Youji Feng
Pages: 1194-1204
Published online on: 06 August 2013

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Article

Discovery of a potent small molecule SIRT1/2 inhibitor with anticancer effects

Gildon Choi, Jongkook Lee, Jeong Yeon Ji, Jimin Woo, Nam Sook Kang, Sung Yun Cho, Hyoung Rae Kim, Jae Du Ha, Sun-Young Han
Pages: 1205-1211
Published online on: 23 July 2013

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Article

MiR-15a is underexpressed and inhibits the cell cycle by targeting CCNE1 in breast cancer

Qifeng Luo, Xiaoyu Li, Jia Li, Xiangjie Kong, Junfeng Zhang, Lei Chen, Yixiang Huang, Lin Fang
Pages: 1212-1218
Published online on: 23 July 2013

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Article

Different therapeutic effects of distinct KISS1 fragments on breast cancer in vitro and in vivo

Guo-Qing Song, Yi Zhao
Pages: 1219-1227
Published online on: 23 July 2013

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Article

RNAi gene therapy of SiHa cells via targeting human TERT induces growth inhibition and enhances radiosensitivity

Wenxuan Zhang, Lina Xing
Pages: 1228-1234
Published online on: 06 August 2013

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Article

Ursolic acid promotes colorectal cancer cell apoptosis and inhibits cell proliferation via modulation of multiple signaling pathways

Jiumao Lin, Youqin Chen, Lihui Wei, Aling Shen, Thomas J. Sferra, Zhenfeng Hong, Jun Peng
Pages: 1235-1243
Published online on: 26 July 2013

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Article

The ENTPD5/mt-PCPH oncoprotein is a catalytically inactive member of the ectonucleoside triphosphate diphosphohydrolase family

Caitlin M. MacCarthy, Vicente Notario
Pages: 1244-1252
Published online on: 06 August 2013

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Article

Construction of conditional lentivirus-mediated shRNA vector targeting the human Mirk gene and identification of RNAi efficiency in rhabdomyosarcoma RD cells

Boming Zhao, Cao Yang, Shuhua Yang, Yong Gao, Jing Wang
Pages: 1253-1259
Published online on: 02 August 2013

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Article

Isolation of mesenchymal stem-like cells in meningioma specimens

Hyo-Yeol Lim, Kyung Min Kim, Bo Kyung Kim, Jin-Kyoung Shim, Ji-Hyun Lee, Yong-Min Huh, Se-Hoon Kim, Eui-Hyun Kim, Eun-Kyung Park, Kyu-Won Shim, Jong Hee Chang, Dong-Seok Kim, Sun Ho Kim, Yong-Kil Hong, Su-Jae Lee, Seok-Gu Kang
Pages: 1260-1268
Published online on: 06 August 2013

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Article

Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells

Gaetano Marverti, Alessio Ligabue, Paolo Lombardi, Stefania Ferrari, Maria Giuseppina Monti, Chiara Frassineti, Maria Paola Costi
Pages: 1269-1280
Published online on: 31 July 2013

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Article

Upregulation of the δ opioid receptor in liver cancer promotes liver cancer progression both in vitro and in vivo Retraction in /10.3892/ijo.2023.5504

Bo Tang, Yang Li, Shengguang Yuan, Stephen Tomlinson, Songqing He
Pages: 1281-1290
Published online on: 31 July 2013

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Article

CAPE promotes TRAIL-induced apoptosis through the upregulation of TRAIL receptors via activation of p38 and suppression of JNK in SK-Hep1 hepatocellular carcinoma cells

Eun Young Kim, Jae-Ha Ryu, An Keun Kim
Pages: 1291-1300
Published online on: 15 July 2013

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Article

Therapeutic potential of human adipose stem cells in a cancer stem cell-like gastric cancer cell model

Guangming Liu, Michael Neumeister, Joel Reichensperger, Russell D. Yang
Pages: 1301-1309
Published online on: 25 July 2013

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Article

Acceptance of human papillomavirus (HPV) vaccination among young women in a country with a high prevalence of HPV infection

Susanna Alder, Claudia Perinetti, Miriam Mints, Karen Belkić, Karin Sundström, Sven Sandin, Elisabete Weiderpass, Sonia Andersson
Pages: 1310-1318
Published online on: 19 July 2013

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Article

Regulation of Wnt signaling activity for growth suppression induced by quercetin in 4T1 murine mammary cancer cells

Haesung Kim, Eun-Min Seo, Ashish R. Sharma, Bilguun Ganbold, Jongbong Park, Garima Sharma, Young-Hee Kang, Dong-Keun Song, Sang-Soo Lee, Ju-Suk Nam
Pages: 1319-1325
Published online on: 23 July 2013

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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