|
1.
|
Argiris A, Karamouzis MV, Raben D and
Ferris RL: Head and neck cancer. Lancet. 371:1695–1709. 2008.
View Article : Google Scholar
|
|
2.
|
Pisani P, Parkin DM and Ferlay J:
Estimates of the worldwide mortality from eighteen major cancers in
1985. implications for prevention and projections of future burden.
Int J Cancer. 55:891–903. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
3.
|
Perez-Ordonez B, Beauchemin M and Jordan
RC: Molecular biology of squamous cell carcinoma of the head and
neck. J Clin Pathol. 59:445–453. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
4.
|
Brait M and Sidransky D: Cancer
epigenetics: Above and beyond. Toxicol Mech Methods. 21:275–288.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
5.
|
Sharma S, Kelly TK and Jones PA:
Epigenetics in cancer. Carcinogenesis. 31:27–36. 2010. View Article : Google Scholar
|
|
6.
|
Laliberte J, Marquez VE and Momparler RL:
Potent inhibitors for the deamination of cytosine arabinoside and
5-aza-2′-deoxycytidine by human cytidine deaminase. Cancer
Chemother Pharmacol. 30:7–11. 1992.PubMed/NCBI
|
|
7.
|
Cheng JC, Matsen CB, Gonzales FA, et al:
Inhibition of DNA methylation and reactivation of silenced genes by
zebularine. J Natl Cancer Inst. 95:399–409. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
8.
|
Pompeia C, Hodge DR, Plass C, Wu YZ,
Marquez VE, Kelley JA and Farrar WL: Microarray analysis of
epigenetic silencing of gene expression in the KAS-6/1 multiple
myeloma cell line. Cancer Res. 64:3465–3473. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
9.
|
Billam M, Sobolewski MD and Davidson NE:
Effects of a novel DNA methyltransferase inhibitor zebularine on
human breast cancer cells. Breast Cancer Res Treat. 120:581–592.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
10.
|
Ben-Kasus T, Ben-Zvi Z, Marquez VE, Kelley
JA and Agbaria R: Metabolic activation of zebularine, a novel DNA
methylation inhibitor, in human bladder carcinoma cells. Biochem
Pharmacol. 70:121–133. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
11.
|
Tan W, Zhou W, Yu HG, Luo HS and Shen L:
The DNA methyltransferase inhibitor zebularine induces
mitochondria-mediated apoptosis in gastric cancer cells in vitro
and in vivo. Biochem Biophys Res Commun. 430:250–255. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
12.
|
You BR and Park WH: Zebularine inhibits
the growth of HeLa cervical cancer cells via cell cycle arrest and
caspase-dependent apoptosis. Mol Biol Rep. 39:9723–9731. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
13.
|
Suzuki M, Shinohara F, Nishimura K, Echigo
S and Rikiishi H: Epigenetic regulation of chemosensitivity to
5-fluorouracil and cisplatin by zebularine in oral squamous cell
carcinoma. Int J Oncol. 31:1449–1456. 2007.PubMed/NCBI
|
|
14.
|
Suzuki M, Shinohara F and Rikiishi H:
Zebularine-induced reduction in VEGF secretion by HIF-1alpha
degradation in oral squamous cell carcinoma. Mol Med Rep.
1:465–471. 2008.PubMed/NCBI
|
|
15.
|
Suzuki M, Shinohara F, Endo M, Sugazaki M,
Echigo S and Rikiishi H: Zebularine suppresses the apoptotic
potential of 5-fluorouracil via cAMP/PKA/CREB pathway against human
oral squamous cell carcinoma cells. Cancer Chemother Pharmacol.
64:223–232. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16.
|
Brakensiek K, Langer F, Kreipe H and
Lehmann U: Absence of p21(CIP 1), p27(KIP 1) and p 57(KIP 2)
methylation in MDS and AML. Leuk Res. 29:1357–1360. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
17.
|
Tort F, Hernandez S, Bea S, et al:
Checkpoint kinase 1 (CHK1) protein and mRNA expression is
downregulated in aggressive variants of human lymphoid neoplasms.
Leukemia. 19:112–117. 2005.PubMed/NCBI
|
|
18.
|
Cheng JC, Yoo CB, Weisenberger DJ, et al:
Preferential response of cancer cells to zebularine. Cancer Cell.
6:151–158. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
19.
|
You BR and Park WH: Zebularine-induced
apoptosis in calu-6 lung cancer cells is influenced by ROS and GSH
level changes. Tumour Biol. 34:1145–1153. 2013. View Article : Google Scholar
|
|
20.
|
Teramen H, Tsukuda K, Tanaka N, et al:
Aberrant methylation of p21 gene in lung cancer and malignant
pleural mesothelioma. Acta Med Okayama. 65:179–184. 2011.PubMed/NCBI
|
