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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
June-2014 Volume 44 Issue 6

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Paracrine effects of stem cells in wound healing and cancer progression (Review)

Jürgen Dittmer, Benjamin Leyh
Pages: 1789-1798
Published online on: 11 April 2014

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Review Open Access

Human papillomavirus and oropharyngeal cancer, the epidemics, and significance of additional clinical biomarkers for prediction of response to therapy (Review)

Tina Dalianis
Pages: 1799-1805
Published online on: 21 March 2014

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Article Open Access

Cancer stem cells and tumor metastasis (Review)

Shuang Li, Qin Li
Pages: 1806-1812
Published online on: 02 April 2014

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Review

The tumor suppressor PTEN interacts with p53 in hereditary cancer (Review)

Atsuko Nakanishi, Yasuko Kitagishi, Yasunori Ogura, Satoru Matsuda
Pages: 1813-1819
Published online on: 10 April 2014

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Article Open Access

Prognostic relevance of KRAS genotype in metastatic colorectal cancer patients unfit for FIr-B/FOx intensive regimen

Gemma Bruera, Katia Cannita, Aldo Victor Giordano, Roberto Vicentini, Corrado Ficorella, Enrico Ricevuto
Pages: 1820-1830
Published online on: 04 April 2014

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Article Open Access

All trans-retinoic acid (ATRA) induces re-differentiation of early transformed breast epithelial cells

Maria F. Arisi, Rebecca A. Starker, Sankar Addya, Yong Huang, Sandra V. Fernandez
Pages: 1831-1842
Published online on: 21 March 2014

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Article Open Access

ERGO: A pilot study of ketogenic diet in recurrent glioblastoma Erratum in /ijo/45/6/2605

Johannes Rieger, Oliver Bähr, Gabriele D. Maurer, Elke Hattingen, Kea Franz, Daniel Brucker, Stefan Walenta, Ulrike Kämmerer, Johannes F. Coy, Michael Weller, Joachim P. Steinbach
Pages: 1843-1852
Published online on: 11 April 2014

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Article Open Access

Downregulation of the CXCR4 receptor inhibits cervical carcinoma metastatic behavior in vitro and in vivo

Małgorzata Sekuła, Katarzyna Miekus, Marcin Majka
Pages: 1853-1860
Published online on: 11 April 2014

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Article Open Access

The influence of lentivirus-mediated CXCR4 RNA interference on hepatic metastasis of colorectal cancer

Tian-Bao Wang, Bao-Guang Hu, Da-Wei Liu, Han-Ping Shi, Wen-Guang Dong
Pages: 1861-1869
Published online on: 19 March 2014

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Article Open Access

A novel microchannel-based device to capture and analyze circulating tumor cells (CTCs) of breast cancer

Reza Riahi, Priyadarshini Gogoi, Saedeh Sepehri, Yi Zhou, Kalyan Handique, Jim Godsey, Yixin Wang
Pages: 1870-1878
Published online on: 21 March 2014

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Article

Molecular targeting of neuroblastoma with a novel p16INK4a transporter system

Takuya Kawaguchi, Kazuhiro Yoshikawa, Keiji Kawamoto, Kunikazu Yoshimura, Hideyuki Oshige, Akio Asai
Pages: 1879-1885
Published online on: 07 April 2014

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Article

Significance of osteopontin in the sensitivity of malignant pleural mesothelioma to pemetrexed

Susumu Takeuchi, Masahiro Seike, Rintaro Noro, Chie Soeno, Teppei Sugano, Fenfei Zou, Haruka Uesaka, Nobuhiko Nishijima, Masaru Matsumoto, Yuji Minegishi, Kaoru Kubota, Akihiko Gemma
Pages: 1886-1894
Published online on: 07 April 2014

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Article

The novel bladder preservation therapy BOAI-CDDP-radiation (OMC-regimen): A new treatment option for invasive bladder cancer patients with lymph node metastasis

Haruhito Azuma, Teruo Inamoto, Kiyoshi Takahara, Hayahito Nomi, Hajime Hirano, Naokazu Ibuki, Hiroshi Uehara, Kazumasa Komura, Koichiro Minami, Taizo Uchimoto, Kenkichi Saito, Tomoaki Takai, Naoki Tanda, Kazuhiro Yamamoto, Yoshihumi Narumi, Satoshi Kiyama
Pages: 1895-1903
Published online on: 10 April 2014

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Article

The expression of miR-30a* and miR-30e* is associated with a dualistic model for grading ovarian papillary serious carcinoma

Yan Wang, Lv Li, Zhenyun Qu, Ruomeng Li, Tie Bi, Jiyong Jiang, Henan Zhao
Pages: 1904-1914
Published online on: 27 March 2014

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Article

MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in hepatocellular carcinogenesis

Xiao-Ran Long, Yong He, Cheng Huang, Jun Li
Pages: 1915-1922
Published online on: 08 April 2014

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Article

MicroRNA-203 inhibits the progression of esophageal squamous cell carcinoma with restored epithelial tissue architecture in vivo

Tomoyuki Okumura, Yutaka Shimada, Makoto Moriyama, Yoshinori Takei, Tetsuya Omura, Shinichi Sekine, Takuya Nagata, Kazuharu Shimizu, Kazuhiro Tsukada
Pages: 1923-1932
Published online on: 02 April 2014

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Article

In vitro and in vivo effects of a nutrient mixture on breast cancer progression

M. W. Roomi, T. Kalinovsky, N. M. Roomi, J. Cha, M. Rath, A. Niedzwiecki
Pages: 1933-1944
Published online on: 10 April 2014

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Article

RUVBL1 directly binds actin filaments and induces formation of cell protrusions to promote pancreatic cancer cell invasion

Keisuke Taniuchi, Mutsuo Furihata, Shinji Iwasaki, Kenjiro Tanaka, Takahiro Shimizu, Motoaki Saito, Toshiji Saibara
Pages: 1945-1954
Published online on: 10 April 2014

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Article

Gene expression signatures for identifying diffuse-type gastric cancer associated with epithelial-mesenchymal transition

Shihori Tanabe, Kazuhiko Aoyagi, Hiroshi Yokozaki, Hiroki Sasaki
Pages: 1955-1970
Published online on: 11 April 2014

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Article

Zebularine induces prolonged apoptosis effects via the caspase-3/PARP pathway in head and neck cancer cells

Tina Napso, Fuad Fares
Pages: 1971-1979
Published online on: 11 April 2014

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Article

Attenuation of malignant phenotypes of breast cancer cells through eIF2α-mediated downregulation of Rac1 signaling

Kazunori Hamamura, Kazumasa Minami, Nancy Tanjung, Qiaoqiao Wan, Masahiko Koizumi, Nariaki Matsuura, Sungsoo Na, Hiroki Yokota
Pages: 1980-1988
Published online on: 02 April 2014

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Article

Suppression of lung cancer cell invasion by LKB1 is due to the downregulation of tissue factor and vascular endothelial growth factor, partly dependent on SP1

Xuan Liang, Zhao-Lun Li, Li-Li Jiang, Qian-Qian Guo, Meng-Jie Liu, Ke-Jun Nan
Pages: 1989-1997
Published online on: 19 March 2014

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Article

Development of a 124I-labeled version of the anti-PSMA monoclonal antibody capromab for immunoPET staging of prostate cancer: Aspects of labeling chemistry and biodistribution

Vladimir Tolmachev, Jennie Malmberg, Sergio Estrada, Olof Eriksson, Anna Orlova
Pages: 1998-2008
Published online on: 10 April 2014

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Article

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes

Jagadish Loganathan, Jiahua Jiang, Amanda Smith, Andrej Jedinak, Anita Thyagarajan-Sahu, George E. Sandusky, Harikrishna Nakshatri, Daniel Sliva
Pages: 2009-2015
Published online on: 09 April 2014

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Article

Antibody ligation of CM1 on cisplatin-exposed HeLa cells induces apoptosis through reactive oxygen species-dependent Fas ligand expression

Ga Bin Park, Daejin Kim, Hoi Soo Yoon, Yeong-Seok Kim, Hyun-Kyung Lee, Ki Tae Kim, Dae Hoon Jeong, Dae Young Hur
Pages: 2016-2024
Published online on: 27 March 2014

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Article

Integrated analysis of expression profiling data identifies three genes in correlation with poor prognosis of triple-negative breast cancer

Cheng Zhang, Yong Han, Hao Huang, Li Min, Like Qu, Chengchao Shou
Pages: 2025-2033
Published online on: 20 March 2014

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Article

Knockdown of NANOG enhances chemosensitivity of liver cancer cells to doxorubicin by reducing MDR1 expression

Jia-Jia Zhou, Xiao-Geng Deng, Xiao-Yu He, Yu Zhou, Min Yu, Wen-Chao Gao, Bing Zeng, Quan-Bo Zhou, Zhi-Hua Li, Ru-Fu Chen
Pages: 2034-2040
Published online on: 19 March 2014

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Article

Linc00963: A novel, long non-coding RNA involved in the transition of prostate cancer from androgen-dependence to androgen-independence

Lijuan Wang, Suxia Han, Guihua Jin, Xia Zhou, Meng Li, Xia Ying, Le Wang, Huili Wu, Qing Zhu
Pages: 2041-2049
Published online on: 02 April 2014

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Article

MicroRNA-26a acts as a tumor suppressor inhibiting gallbladder cancer cell proliferation by directly targeting HMGA2

Huading Zhou, Weijie Guo, Yingjun Zhao, Yifei Wang, Ruopeng Zha, Jie Ding, Linhui Liang, Jun Hu, Hao Shen, Zongyou Chen, Baobing Yin, Baojin Ma
Pages: 2050-2058
Published online on: 27 March 2014

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Article

The expression and phosphorylation of ezrin and merlin in human pancreatic cancer

Jiahua Zhou, Yongjiang Feng, Ketao Tao, Zhanhai Su, Xiaojin Yu, Jie Zheng, Lihua Zhang, Detong Yang
Pages: 2059-2067
Published online on: 10 April 2014

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Article

High-resolution detection of recurrent aberrations in lung adenocarcinomas by array comparative genomic hybridization and expression analysis of selective genes by quantitative PCR

Hong Zhu, Maria Pik Wong, Vicky Tin
Pages: 2068-2076
Published online on: 11 April 2014

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Article

HIF-1α activation under glucose deprivation plays a central role in the acquisition of anti-apoptosis in human colon cancer cells

Arata Nishimoto, Naruji Kugimiya, Tohru Hosoyama, Tadahiko Enoki, Tao-Sheng Li, Kimikazu Hamano
Pages: 2077-2084
Published online on: 03 April 2014

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Article

microRNA-504 inhibits cancer cell proliferation via targeting CDK6 in hypopharyngeal squamous cell carcinoma

Naoko Kikkawa, Takashi Kinoshita, Nijiro Nohata, Toyoyuki Hanazawa, Noriko Yamamoto, Ichiro Fukumoto, Takeshi Chiyomaru, Hideki Enokida, Masayuki Nakagawa, Yoshitaka Okamoto, Naohiko Seki
Pages: 2085-2092
Published online on: 19 March 2014

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Article

Downregulation of thymidylate synthase with arsenic trioxide in lung adenocarcinoma

Sze-Kwan Lam, Judith Choi-Wo Mak, Chun-Yan Zheng, Yuan-Yuan Li, Yok-Lam Kwong, James Chung-Man Ho
Pages: 2093-2102
Published online on: 02 April 2014

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Article

The secretion of IL-6 by CpG-ODN-treated cancer cells promotes T-cell immune responses partly through the TLR-9/AP-1 pathway in oral squamous cell carcinoma

Min Ruan, Katherine Thorn, Shengwen Liu, Siyi Li, Wenjun Yang, Chunye Zhang, Chenping Zhang
Pages: 2103-2110
Published online on: 21 March 2014

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Article

Hypoxia-induced miR-210 in epithelial ovarian cancer enhances cancer cell viability via promoting proliferation and inhibiting apoptosis

Li'an Li, Ke Huang, Yanqin You, Xiaoyu Fu, Lingyun Hu, Lei Song, Yuanguang Meng
Pages: 2111-2120
Published online on: 04 April 2014

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Article

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay

Francesco Marampon, Giovanni Luca Gravina, Bianca Maria Zani, Vladimir M. Popov, Amato Fratticci, Manuela Cerasani, Daniela Di Genova, Marta Mancini, Carmela Ciccarelli, Corrado Ficorella, Ernesto Di Cesare, Claudio Festuccia
Pages: 2121-2131
Published online on: 24 March 2014

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Article

Combination of dasatinib and gemcitabine reduces the ALDH1A1 expression and the proliferation of gemcitabine-resistant pancreatic cancer MIA PaCa-2 cells

Hong-Quan Duong, Yong Weon Yi, Hyo Jin Kang, Insoo Bae, Young-Joo Jang, Sahng-June Kwak, Yeon-Sun Seong
Pages: 2132-2138
Published online on: 21 March 2014

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Article

A triple combination of atorvastatin, celecoxib and tipifarnib strongly inhibits pancreatic cancer cells and xenograft pancreatic tumors

Ning Ding, Xiao-Xing Cui, Zhi Gao, Huarong Huang, Xingchuan Wei, Zhiyun Du, Yong Lin, Weichung Joe Shih, Arnold B. Rabson, Allan H. Conney, Chunhong Hu, Xi Zheng
Pages: 2139-2145
Published online on: 19 March 2014

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Article

Factors associated with dropout in a lung cancer high‑risk cohort - the Liverpool lung project

Michael W. Marcus, Olaide Y. Raji, Ying Chen, Stephen W. Duffy, John K. Field
Pages: 2146-2152
Published online on: 07 April 2014

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Article

p63 regulates growth of esophageal squamous carcinoma cells via the Akt signaling pathway

Shuai Ye, Kwang Bok Lee, Man Hee Park, Ju-Seog Lee, Soo Mi Kim
Pages: 2153-2159
Published online on: 09 April 2014

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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