|
1
|
Lim J and Thiery JP:
Epithelial-mesenchymal transitions: insights from development.
Development. 139:3471–3486. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Willis BC and Borok Z: TGF-beta-induced
EMT: mechanisms and implications for fibrotic lung disease. Am J
Physiol Lung Cell Mol Physiol. 293:525–534. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Savagner P: The epithelial-mesenchymal
transition (EMT) phenomenon. Ann Oncol. 21(Suppl 7): vii89–vii92.
View Article : Google Scholar : 2010. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Xu J, Lamouille S and Derynck R:
TGF-beta-induced epithelial to mesenchymal transition. Cell Res.
19:156–172. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Yilmaz M and Christofori G: EMT, the
cytoskeleton, and cancer cell invasion. Cancer Metastasis Rev.
28:15–33. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Li H, Wang H, Wang F, Gu Q and Xu X: Snail
involves in the transforming growth factor β1-mediated
epithelial-mesenchymal transition of retinal pigment epithelial
cells. PLoS One. 6:e233222011.
|
|
8
|
Margetts PJ: Twist: a new player in the
epithelial-mesenchymal transition of the peritoneal mesothelial
cells. Nephrol Dial Transplant. 27:3978–3981. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Onder TT, Gupta PB, Mani SA, Yang J,
Lander ES and Weinberg RA: Loss of E-cadherin promotes metastasis
via multiple downstream transcriptional pathways. Cancer Res.
68:3645–3654. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Luo W, Fang W, Li S and Yao K: Aberrant
expression of nuclear vimentin and related epithelial-mesenchymal
transition markers in nasopharyngeal carcinoma. Int J Cancer.
131:1863–1873. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Pagan R, Sánchez A, Martin I, Llobera M,
Fabregat I and Vilaró S: Effects of growth and differentiation
factors on the epithelial-mesenchymal transition in cultured
neonatal rat hepatocytes. J Hepatol. 31:895–904. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Saitoh M and Miyazawa K: Transcirptional
and post-transcriptional regulation in TGF-β-mediated
epithelial-mesenchymal transition. J Biochem. 151:563–571.
2012.
|
|
13
|
American Thoracic Society, European
Respiration Society. American Thoracic Society/European Respiration
Society international multidisciplinary consensus classification of
the idiopathic interstitial pneumonias. Am J Respir Crit Care Med.
165:277–304. 2002.
|
|
14
|
Selman M and Pardo A: Alveolar epithelial
cell disintegrity and subsequent activation: a key process in
pulmonary fibrosis. Am J Respir Crit Care Med. 186:119–121. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Marmai C, Sutheriand RE, Kim KK, et al:
Alveolar epithelial cells express mesenchymal proteins in patients
with idiopathic pulmonary fibrosis. Am J Physiol Lung Cell Mol
Physiol. 301:L71–L78. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kolosova I, Nethery D and Kern JA: Role of
Smad2/3 and p38 MAP kinase in TGF-β1-induced epithelial-mesenchymal
transition of pulmonary epithelial cells. J Cell Physiol.
226:1248–1254. 2011.
|
|
17
|
Tsukita S and Yonemura S: Cortical actin
organization: lessons from ERM (ezrin/radixin/moesin) proteins. J
Biol Chem. 274:34507–34510. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Tsukita S, Oishi K, Sato N, Sagara J,
Kawai A and Tsukita S: ERM family members as molecular linkers
between the cell surface glycoprotein CD44 and actin-based
cytoskeletons. J Cell Biol. 126:391–401. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Buckley ST, Medina C, Kasper M and
Ehrhardt C: Interplay between RAGE, CD44, and focal adhesion
molecules in epithelial-mesenchymal transition of alveolar
epithelial cells. Am J Physiol Lung Cell Mol Physiol.
300:L548–L559. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Ehrhardt C, Medina C and Buckley ST:
Interaction of RAGE with focal adhesion molecules during alveolar
epithelial-mesenchymal transition. FASEB J. 25:8652011.
|
|
21
|
Haynes J, Srivastava J, Madson N, Wittmann
T and Barber DL: Dynamic actin remodeling during
epithelial-mesenchymal transition depends on increased moesin
expression. Mol Biol Cell. 22:4750–4764. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Nielsen JS and McNagny KM: The role of
podocalyxin in health and disease. J Am Soc Nephrol. 20:1669–1676.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Orlando RA, Takeda T, Zak B, et al: The
glomerular epithelial cell anti-adhesin podocalyxin associates with
the actin cytoskeleton through interaction with ezrin. J Am Soc
Nephrol. 12:1589–1598. 2001.PubMed/NCBI
|
|
24
|
Li Y, Li J, Straight SW and Kershaw DB:
PDZ domain-mediated interaction of rabbit podocalyxin and
Na(+)/H(+) exchange regulatory factor-2. Am J Physiol Renal
Physiol. 282:1129–1139. 2002.PubMed/NCBI
|
|
25
|
Sizemore S, Cicek M, Sizemore N, Ng KP and
Casey G: Podocalyxin increases the aggressive phenotype of breast
and prostate cancer cells in vitro through its interaction with
ezrin. Cancer Res. 67:6183–6191. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Meng X, Ezzati P and Wilkins JA:
Requirement of podocalyxin in TGF-beta induced epithelial
mesenchymal transition. PLoS One. 6:e187152011. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Ohtani K, Sakamoto H, Rutherford T, Chen
Z, Satoh K and Naftolin F: Ezrin, a membrane-cytoskeletal linking
protein, is involved in the process of invasion of endometrial
cancer cells. Cancer Lett. 147:31–38. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Elliott BE, Meens JA, SenGupta SK, Louvard
D and Arpin M: The membrane cytoskeletal crosslinker ezrin is
required for metastasis of breast carcinoma cells. Breast Cancer
Res. 7:R365–R373. 2005. View
Article : Google Scholar : PubMed/NCBI
|
|
29
|
Osawa H, Smith CA, Ra YS, Kongkham P and
Rutka JT: The role of the membrane cytoskeleton cross-linker ezrin
in medulloblastoma cells. Neuro Oncol. 11:381–393. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Cant SH and Pitcher JA: G protein-coupled
receptor kinase 2-mediated phosphorylation of ezrin is required for
G protein-coupled receptor-dependent reorganization of the actin
cytoskeleton. Mol Biol Cell. 16:3088–3099. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Crepaldi T, Gautreau A, Comoglio PM,
Louvard D and Arpin M: Ezrin is an effector of hepatocyte growth
factor-mediated migration and morphogenesis in epithelial cells. J
Cell Biol. 138:423–434. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Huang HY, Li CF, Fang FM, Tsai JW, Li SH,
Lee YT and Wei HM: Prognostic implication of ezrin overexpression
in myxofibrosarcomas. Ann Surg Oncol. 17:3212–3219. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Li Q, Gao H, Xu H, et al: Expression of
ezrin correlates with malignant phenotype of lung cancer, and in
vitro knockdown of ezrin reverses the aggressive biological
behavior of lung cancer cells. Tumour Biol. 33:1493–1504. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sarrió D, Rodríguez-Pinilla SM, Dotor A,
Calero F, Hardisson D and Palacios J: Abnormal ezrin localization
is associated with clinicopathological features in invasive breast
carcinomas. Breast Cancer Res Treat. 98:71–79. 2006.PubMed/NCBI
|
|
35
|
Pérez P, Aguilera S, Olea N, et al:
Aberrant localization of ezrin correlates with salivary acini
disorganization in Sjögren’s Syndrome. Rheumatology. 49:915–923.
2010.PubMed/NCBI
|
|
36
|
Arslan AA, Silvera D, Arju R, Giashuddin
S, Belitskaya-Levy I, Formenti SC and Schneider RJ: Atypical ezrin
localization as a marker of locally advanced breast cancer. Breast
Cancer Res Treat. 134:981–988. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Berryman M, Franck Z and Bretscher A:
Ezrin is concentrated in the apical microvilli of a wide variety of
epithelial cells whereas moesin is found primarily in endothelial
cells. J Cell Sci. 105:1025–1043. 1993.
|
|
38
|
Bretscher A, Edwards K and Fehon RG: ERM
proteins and merlin: integrators at the cell cortex. Nat Rev Mol
Cell Biol. 3:586–599. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
39
|
Moilanen J, Lassus H, Leminen A, Vaheri A,
Bützow R and Carpén O: Ezrin immunoreactivity in relation to
survival in serous ovarian carcinoma patients. Gynecol Oncol.
90:273–281. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Tokunou M, Niki T, Saitoh Y, Imamura H,
Sakamoto M and Hirohashi S: Altered expression of the ERM proteins
in lung adenocarcinoma. Lab Invest. 80:1643–1650. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Gautreau A, Louvard D and Arpin M:
Morphogenic effects of ezrin require a phosphorylation-induced
transition from oligomers to monomers at the plasma membrane. J
Cell Biol. 150:193–203. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Bretscher A: Rapid phosphorylation and
reorganization of ezrin and spectrin accompany morphological
changes induced in A-431 cells by epidermal growth factor. J Cell
Biol. 108:921–930. 1989. View Article : Google Scholar
|
|
43
|
Jiang WG, Hiscox S, Singhrao SK, Puntis
MC, Nakamura T, Mansel RE and Hallett MB: Induction of tyrosine
phosphorylation and translocation of ezrin by hepatocyte growth
factor/scatter factor. Biochem Biophys Res Commun. 217:1062–1069.
1995. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Chen Z, Fadiel A, Feng Y, Ohtani K,
Rutherford T and Naftolin F: Ovarian epithelial carcinoma tyrosine
phosphorylation, cell proliferation, and ezrin translocation are
stimulated by interleukin 1alpha and epidermal growth factor.
Cancer. 92:3068–3075. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Martin TA, Harrison G, Mansel RE and Jiang
WG: The role of the CD44/ezrin complex in cancer metastasis. Crit
Rev Oncol Hematol. 46:165–186. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Weinman EJ, Steplock D, Donowitz M and
Shenolikar S: NHERF associations with sodium-hydrogen exchanger
isoform 3 (NHE3) and ezrin are essential for cAMP-mediated
phosphorylation and inhibition of NHE3. Biochemistry. 39:6123–6129.
2000. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Heiska L, Alfthan K, Grönholm M, Vilja P,
Vaheri A and Carpén O: Association of ezrin with intercellular
adhesion molecule-1 and -2 (ICAM-1 and ICAM-2). Regulation by
phosphatidylinositol 4, 5-bisphosphate. J Biol Chem.
273:21893–21900. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Schmieder S, Nagai M, Oriando RA, Takeda T
and Farquhar MG: Podocalyxin activates RhoA and induces actin
reorganization through NHERF1 and ezrin in MDCK cells. J Am Soc
Nephrol. 15:2289–2298. 2004. View Article : Google Scholar : PubMed/NCBI
|
