Journal Articles
Review
Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (Review)
Hanns Möhler, Rolf W. Pfirrmann, Karl Frei
Pages: 1329-1336 Published online on: 28 July 2014
Review
Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (Review)
Björn Georgi, Nina Korzeniewski, Boris Hadaschik, Carsten Grüllich, Wilfried Roth, Holger Sültmann, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Pages: 1337-1344 Published online on: 28 July 2014
Review
Clinical impact of the Warburg effect in gastrointestinal cancer (Review)
Hiroshi Sawayama, Takatsugu Ishimoto, Hidetaka Sugihara, Nobutomo Miyanari, Yuji Miyamoto, Yoshifumi Baba, Naoya Yoshida, Hideo Baba
Pages: 1345-1354 Published online on: 25 July 2014
Review
Roles of the calcium sensing receptor in digestive physiology and pathophysiology (Review)
Rui Xie, Bo Tang, Xin Yong, Gang Luo, Shi-Ming Yang
Pages: 1355-1362 Published online on: 25 July 2014
Review
TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)
Katsunori Yoshida, Miki Murata, Takashi Yamaguchi, Koichi Matsuzaki
Pages: 1363-1371 Published online on: 22 July 2014
Article
A subset of bone marrow stromal cells regulate ATP-binding cassette gene expression via insulin-like growth factor-I in a leukemia cell line
Nadia Benabbou, Pezhman Mirshahi, Camille Bordu, Anne-Marie Faussat, Ruoping Tang, Amu Therwath, Jeannette Soria, Jean-Pierre Marie, Massoud Mirshahi
Pages: 1372-1380 Published online on: 29 July 2014
Article
A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes
Ryouichi Tsunedomi, Shoichi Hazama, Yusuke Fujita, Naoko Okayama, Shinsuke Kanekiyo, Yuka Inoue, Shigefumi Yoshino, Takahiro Yamasaki, Yutaka Suehiro, Koji Oba, Hideyuki Mishima, Junichi Sakamoto, Yoshihiko Hamamoto, Masaaki Oka
Pages: 1381-1390 Published online on: 22 July 2014
Article
Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition
Mahesh Appari, Kamesh R. Babu, Adam Kaczorowski, Wolfgang Gross, Ingrid Herr
Pages: 1391-1400 Published online on: 08 July 2014
Article
Motility of select ovarian cancer cell lines: Effect of extracellular matrix proteins and the involvement of PAK2
Elizabeth Flate, John R.D. Stalvey
Pages: 1401-1411 Published online on: 22 July 2014
Article
A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model
Kosuke Higashi, Shoichi Hazama, Atsuhiro Araki, Kiyoshi Yoshimura, Norio Iizuka, Shigefumi Yoshino, Takafumi Noma, Masaaki Oka
Pages: 1412-1420 Published online on: 22 July 2014
Article
Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor
Loredana Vesci, Ferdinando Maria Milazzo, Valeria Carollo, Silvia Pace, Giuseppe Giannini
Pages: 1421-1429 Published online on: 01 August 2014
Article
Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition
Akihiro Kogita, Yosuke Togashi, Hidetoshi Hayashi, Shunsuke Sogabe, Masato Terashima, Marco A. De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yoshifumi Takeyama, Kiyotaka Okuno, Kazuhiko Nakagawa, Kazuto Nishio
Pages: 1430-1436 Published online on: 01 August 2014
Article
microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting CDH2 and IGF1R
Kang Han, Tingbao Zhao, Xiang Chen, Na Bian, Tongtao Yang, Qiong Ma, Chengkui Cai, Qingyu Fan, Yong Zhou, Baoan Ma
Pages: 1437-1449 Published online on: 30 July 2014
Article
Genetic screen identifies suppressor of morphogenesis in genitalia-1 (SMG-1) as a modulator of sorafenib resistance in hepatocellular carcinoma cell lines
Soon Woo Nam, Ki Cheol Park, Keum Jin Yang, Byoungchun Lee, Sung-Woo Kim
Pages: 1450-1456 Published online on: 10 July 2014
Article
ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models
Kyriaki Ioannou, Kai Fan Cheng, Gregg V. Crichlow, Anastasios I. Birmpilis, Elias J. Lolis, Ourania E. Tsitsilonis, Yousef Al-Abed
Pages: 1457-1468 Published online on: 22 July 2014
Article
Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2
Zhiyu Wang, Juan Wang, Xing Li, Lianping Xing, Yan Ding, Penghui Shi, Yuehua Zhang, Shenghu Guo, Xin Shu, Baoen Shan
Pages: 1469-1478 Published online on: 17 July 2014
Article
Cancer-associated fibroblasts from invasive breast cancer have an attenuated capacity to secrete collagens
Zhixuan Fu, Peiming Song, Dongbo Li, Chenghao Yi, Huarong Chen, Shuqin Ruan, Zhong Shi, Wenhong Xu, Xianhua Fu, Shu Zheng
Pages: 1479-1488 Published online on: 25 July 2014
Article
Expression of the Bcl-2 family genes and complexes involved in the mitochondrial transport in prostate cancer cells
Asmarinah Asmarinah, Agnieszka Paradowska-Dogan, Ria Kodariah, Budiana Tanuhardja, Przemyslaw Waliszewski, Chaidir Arif Mochtar, Yuli Budiningsih, Wolfgang Weidner, Elvira Hinsch
Pages: 1489-1496 Published online on: 01 August 2014
Article
Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: The involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway
Guk Heui Jo, Gi-Young Kim, Wun-Jae Kim, Kun Young Park, Yung Hyun Choi
Pages: 1497-1506 Published online on: 04 July 2014
Article
KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α
Xiaochen Li, Xiansheng Liu, Yongjian Xu, Jin Liu, Min Xie, Wang Ni, Shixin Chen
Pages: 1507-1514 Published online on: 17 July 2014
Article
Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells
Miao-Juan Chen, Xue-Juan Gao, Li-Na Xu, Teng-Fei Liu, Xiao-Hui Liu, Lang-Xia Liu
Pages: 1515-1522 Published online on: 22 July 2014
Article
Histone deacetylase 3 promotes pancreatic cancer cell proliferation, invasion and increases drug-resistance through histone modification of P27, P53 and Bax
Feng Jiao, Hai Hu, Cuncun Yuan, Ziliang Jin, Zhen Guo, Liwei Wang, Lei Wang
Pages: 1523-1530 Published online on: 29 July 2014
Article
18F-FDG PET/CT can be used to detect non-functioning pancreatic neuroendocrine tumors
Guopei Luo, Zuqiang Liu, Meng Guo, Kaizhou Jin, Zhiwen Xiao, Liang Liu, Jin Xu, Bo Zhang, Chen Liu, Dan Huang, Silong Hu, Quanxing Ni, Jiang Long, Xianjun Yu
Pages: 1531-1536 Published online on: 29 July 2014
Article
miR‑222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma Retraction in /10.3892/ijo.2021.5280
Kai Liu, Songyang Liu, Wei Zhang, Bai Ji, Yingchao Wang, Yahui Liu
Pages: 1537-1546 Published online on: 04 August 2014
Article
Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma
Jia Li, Jian-Zhi Gao, Jing-Li Du, Zhong-Xi Huang, Li-Xin Wei
Pages: 1547-1555 Published online on: 24 July 2014
Article
An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations
Yuliang Liu, Haukur Gudnason, Yi-Ping Li, Dang Duong Bang, Anders Wolff
Pages: 1556-1564 Published online on: 11 July 2014
Article
Therapeutic potential of capillary morphogenesis gene 2 extracellular vWA domain in tumour‑related angiogenesis
Lin Ye, Ping-Hui Sun, Andrew J. Sanders, Tracey A. Martin, Jane Lane, Malcolm D. Mason, Wen G. Jiang
Pages: 1565-1573 Published online on: 03 July 2014
Article
BTG1 expression in thyroid carcinoma: Diagnostic indicator and prognostic marker
Y. F. Lu, G. G. Sun, Q. Liu, C. R. Yang, Y. J. Cheng
Pages: 1574-1582 Published online on: 11 July 2014
Article
Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity
Susumu Nakata, Harunari Tanaka, Yuichi Ito, Masayasu Hara, Mitsugu Fujita, Eisaku Kondo, Yukihide Kanemitsu, Yasushi Yatabe, Hayao Nakanishi
Pages: 1583-1593 Published online on: 08 July 2014
Article
USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma
Zhen Ning, Aman Wang, Jinxiao Liang, Yunpeng Xie, Jiwei Liu, Lu Feng, Qiu Yan, Zhongyu Wang
Pages: 1594-1608 Published online on: 03 July 2014
Article
Inhibition of activated Ras suppresses multiple oncogenic Hub genes in human epithelial tumors
Lei Cao, Ping Wang, Hui Luo, Xi-Rui Wang, Xie-Feng Wang, Jun-Xia Zhang, Ying-Yi Wang, Lei Yao, Ning Liu, Yong-Ping You
Pages: 1609-1617 Published online on: 03 July 2014
Article
Altered microRNA expression profiles are involved in resistance to low-dose ionizing radiation in the absence of BMI1 in human dermal fibroblasts
Seunghee Bae, Karam Kim, Hwa Jun Cha, Yeongmin Choi, Shang Hun Shin, In-Sook An, Jae Ho Lee, Jie-Young Song, Kwang Hee Yang, Seon Young Nam, Sungkwan An
Pages: 1618-1628 Published online on: 11 July 2014
Article
Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB‑231 partly through suppression of the Akt pathway
Hana Jin, Won Sup Lee, So Young Eun, Ji Hyun Jung, Hyeon-Soo Park, Gonsup Kim, Yung Hyun Choi, Chung Ho Ryu, Jin Myung Jung, Soon Chan Hong, Sung Chul Shin, Hye Jung Kim
Pages: 1629-1637 Published online on: 04 July 2014
Article
Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/β-catenin pathway
Qian Sun, Ronghua Wang, Jing Luo, Peng Wang, Si Xiong, Man Liu, Bin Cheng
Pages: 1638-1648 Published online on: 07 July 2014
Article
Silencing of CXCR7 gene represses growth and invasion and induces apoptosis in colorectal cancer through ERK and β-arrestin pathways
Xin-Xiang Li, Hong-Tu Zheng, Li-Yong Huang, De-Bing Shi, Jun-Jie Peng, Lei Liang, San-Jun Cai
Pages: 1649-1657 Published online on: 21 July 2014
Article
The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer
Miguel Muñoz, Ana González-Ortega, Manuel Vicente Salinas-Martín, Andrés Carranza, Susana Garcia-Recio, Vanessa Almendro, Rafael Coveñas
Pages: 1658-1672 Published online on: 28 July 2014
Article
Torilis japonica extract, a new potential EMT suppressor agent by regulation of EGFR signaling pathways
Guen Tae Kim, Se Hee Lee, Young Min Kim
Pages: 1673-1679 Published online on: 17 July 2014
Article
BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L)
Ji Hoon Jang, Yoon Chul Cho, Ki Ho Kim, Kyung Seop Lee, Jinho Lee, Dong Eun Kim, Jun-Soo Park, Byeong-Churl Jang, Shin Kim, Taeg Kyu Kwon, Jong-Wook Park
Pages: 1680-1690 Published online on: 04 July 2014
Article
Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53
See-Hyoung Park, Jung Han Lee, Jonathan S. Berek, Mickey C.-T. Hu
Pages: 1691-1698 Published online on: 04 August 2014
Article
The cytoplasmic domain of N-cadherin modulates MMP‑9 induction in oral squamous carcinoma cells
Andrew Walker, Rhett Frei, Kathryn R. Lawson
Pages: 1699-1706 Published online on: 21 July 2014
Article
Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation
Sang-Woo Kim, Matthew Schifano, David Oleksyn, Craig T. Jordan, Daniel Ryan, Richard Insel, Jiyong Zhao, Luojing Chen
Pages: 1707-1714 Published online on: 04 August 2014
Article
Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells
Silke Götze, Monique Coersmeyer, Oliver Müller, Sonja Sievers
Pages: 1715-1723 Published online on: 21 July 2014
Article
Evaluation of meisoindigo, an indirubin derivative: in vitro antileukemic activity and in vivo pharmacokinetics
Meng Huang, Hai-Shu Lin, Ying Shiuan Lee, Paul C. Ho
Pages: 1724-1734 Published online on: 21 July 2014
Article
Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin
Yong Bo Liu, Xiaohua Gao, Dorrah Deeb, Chris Brigolin, Yiguan Zhang, Jiajiu Shaw, Kirit Pindolia, Subhash C. Gautam
Pages: 1735-1741 Published online on: 25 July 2014
Article
Mechanisms and potential molecular markers of early response to combination epigenetic therapy in patients with myeloid malignancies
H. B. Liu, D. Urbanavicius, P. Tan, A. Spencer, A. E. Dear
Pages: 1742-1748 Published online on: 22 July 2014
Article
Cytotoxic effects of pyrrolidine dithiocarbamate in small-cell lung cancer cells, alone and in combination with cisplatin
Shinichi Tahata, Bo Yuan, Hidetomo Kikuchi, Norio Takagi, Toshihiko Hirano, Hiroo Toyoda
Pages: 1749-1759 Published online on: 28 July 2014
Article
Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways
Pham Ngoc Khoi, Yong Xia, Sen Lian, Ho Dong Kim, Do Hyun Kim, Young Eun Joo, Kee-Oh Chay, Kyung Keun Kim, Young Do Jung
Pages: 1760-1768 Published online on: 22 July 2014
Article