Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 1019-6439 Online ISSN: 1791-2423
presentation
International Journal of Oncology

Join Editorial Board Propose a Special Issue

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

  • Selected Issue
  • Current Issue
  • Forthcoming Issue
  • Special Issues
    • Open Special Issues
    • About Special Issues
  • Trending Articles
    • Most Read
    • Most Cited (Dimensions)
      • Past Two Years
      • Total
    • Most Cited (Crossref)
      • Past Year
      • Total
    • Social Media
      • Past Month
      • Past Year
      • Total
  • Information
    • Information for Authors
    • Contact
    • Editorial Policies
    • Editorial Academy
    • Aims and Scope
    • Abstracting and Indexing
    • Bibliographic Information
  • Archive
Journal Cover
October 2014 Volume 45 Issue 4

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

Redox-directed cancer therapeutics: Taurolidine and Piperlongumine as broadly effective antineoplastic agents (Review)

Hanns Möhler, Rolf W. Pfirrmann, Karl Frei
Pages: 1329-1336
Published online on: 28 July 2014

  • View Full Article Download
Review

Evolving therapeutic concepts in prostate cancer based on genome-wide analyses (Review)

Björn Georgi, Nina Korzeniewski, Boris Hadaschik, Carsten Grüllich, Wilfried Roth, Holger Sültmann, Sascha Pahernik, Markus Hohenfellner, Stefan Duensing
Pages: 1337-1344
Published online on: 28 July 2014

  • View Full Article Download
Review

Clinical impact of the Warburg effect in gastrointestinal cancer (Review)

Hiroshi Sawayama, Takatsugu Ishimoto, Hidetaka Sugihara, Nobutomo Miyanari, Yuji Miyamoto, Yoshifumi Baba, Naoya Yoshida, Hideo Baba
Pages: 1345-1354
Published online on: 25 July 2014

  • View Full Article Download
Review

Roles of the calcium sensing receptor in digestive physiology and pathophysiology (Review)

Rui Xie, Bo Tang, Xin Yong, Gang Luo, Shi-Ming Yang
Pages: 1355-1362
Published online on: 25 July 2014

  • View Full Article Download
Review Open Access

TGF-β/Smad signaling during hepatic fibro-carcinogenesis (Review)

Katsunori Yoshida, Miki Murata, Takashi Yamaguchi, Koichi Matsuzaki
Pages: 1363-1371
Published online on: 22 July 2014

  • View Full Article Download
Article Open Access

A subset of bone marrow stromal cells regulate ATP-binding cassette gene expression via insulin-like growth factor-I in a leukemia cell line

Nadia Benabbou, Pezhman Mirshahi, Camille Bordu, Anne-Marie Faussat, Ruoping Tang, Amu Therwath, Jeannette Soria, Jean-Pierre Marie, Massoud Mirshahi
Pages: 1372-1380
Published online on: 29 July 2014

  • View Full Article Download
Article Open Access

A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes

Ryouichi Tsunedomi, Shoichi Hazama, Yusuke Fujita, Naoko Okayama, Shinsuke Kanekiyo, Yuka Inoue, Shigefumi Yoshino, Takahiro Yamasaki, Yutaka Suehiro, Koji Oba, Hideyuki Mishima, Junichi Sakamoto, Yoshihiko Hamamoto, Masaaki Oka
Pages: 1381-1390
Published online on: 22 July 2014

  • View Full Article Download
Article Open Access

Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition

Mahesh Appari, Kamesh R. Babu, Adam Kaczorowski, Wolfgang Gross, Ingrid Herr
Pages: 1391-1400
Published online on: 08 July 2014

  • View Full Article Download
Article Open Access

Motility of select ovarian cancer cell lines: Effect of extra­cellular matrix proteins and the involvement of PAK2

Elizabeth Flate, John R.D. Stalvey
Pages: 1401-1411
Published online on: 22 July 2014

  • View Full Article Download
Article Open Access

A novel cancer vaccine strategy with combined IL-18 and HSV-TK gene therapy driven by the hTERT promoter in a murine colorectal cancer model

Kosuke Higashi, Shoichi Hazama, Atsuhiro Araki, Kiyoshi Yoshimura, Norio Iizuka, Shigefumi Yoshino, Takafumi Noma, Masaaki Oka
Pages: 1412-1420
Published online on: 22 July 2014

  • View Full Article Download
Article Open Access

Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor

Loredana Vesci, Ferdinando Maria Milazzo, Valeria Carollo, Silvia Pace, Giuseppe Giannini
Pages: 1421-1429
Published online on: 01 August 2014

  • View Full Article Download
Article Open Access

Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition

Akihiro Kogita, Yosuke Togashi, Hidetoshi Hayashi, Shunsuke Sogabe, Masato Terashima, Marco A. De Velasco, Kazuko Sakai, Yoshihiko Fujita, Shuta Tomida, Yoshifumi Takeyama, Kiyotaka Okuno, Kazuhiko Nakagawa, Kazuto Nishio
Pages: 1430-1436
Published online on: 01 August 2014

  • View Full Article Download
Article Open Access

microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targeting CDH2 and IGF1R

Kang Han, Tingbao Zhao, Xiang Chen, Na Bian, Tongtao Yang, Qiong Ma, Chengkui Cai, Qingyu Fan, Yong Zhou, Baoan Ma
Pages: 1437-1449
Published online on: 30 July 2014

  • View Full Article Download
Article

Genetic screen identifies suppressor of morphogenesis in genitalia-1 (SMG-1) as a modulator of sorafenib resistance in hepatocellular carcinoma cell lines

Soon Woo Nam, Ki Cheol Park, Keum Jin Yang, Byoungchun Lee, Sung-Woo Kim
Pages: 1450-1456
Published online on: 10 July 2014

  • View Full Article Download
Article

ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models

Kyriaki Ioannou, Kai Fan Cheng, Gregg V. Crichlow, Anastasios I. Birmpilis, Elias J. Lolis, Ourania E. Tsitsilonis, Yousef Al-Abed
Pages: 1457-1468
Published online on: 22 July 2014

  • View Full Article Download
Article

Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2

Zhiyu Wang, Juan Wang, Xing Li, Lianping Xing, Yan Ding, Penghui Shi, Yuehua Zhang, Shenghu Guo, Xin Shu, Baoen Shan
Pages: 1469-1478
Published online on: 17 July 2014

  • View Full Article Download
Article

Cancer-associated fibroblasts from invasive breast cancer have an attenuated capacity to secrete collagens Corrigendum in /10.3892/ijo.2024.5675

Zhixuan Fu, Peiming Song, Dongbo Li, Chenghao Yi, Huarong Chen, Shuqin Ruan, Zhong Shi, Wenhong Xu, Xianhua Fu, Shu Zheng
Pages: 1479-1488
Published online on: 25 July 2014

  • View Full Article Download
Article

Expression of the Bcl-2 family genes and complexes involved in the mitochondrial transport in prostate cancer cells

Asmarinah Asmarinah, Agnieszka Paradowska-Dogan, Ria Kodariah, Budiana Tanuhardja, Przemyslaw Waliszewski, Chaidir Arif Mochtar, Yuli Budiningsih, Wolfgang Weidner, Elvira Hinsch
Pages: 1489-1496
Published online on: 01 August 2014

  • View Full Article Download
Article

Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: The involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway

Guk Heui Jo, Gi-Young Kim, Wun-Jae Kim, Kun Young Park, Yung Hyun Choi
Pages: 1497-1506
Published online on: 04 July 2014

  • View Full Article Download
Article

KLF5 promotes hypoxia-induced survival and inhibits apoptosis in non-small cell lung cancer cells via HIF-1α

Xiaochen Li, Xiansheng Liu, Yongjian Xu, Jin Liu, Min Xie, Wang Ni, Shixin Chen
Pages: 1507-1514
Published online on: 17 July 2014

  • View Full Article Download
Article

Ezrin is required for epithelial-mesenchymal transition induced by TGF-β1 in A549 cells

Miao-Juan Chen, Xue-Juan Gao, Li-Na Xu, Teng-Fei Liu, Xiao-Hui Liu, Lang-Xia Liu
Pages: 1515-1522
Published online on: 22 July 2014

  • View Full Article Download
Article

Histone deacetylase 3 promotes pancreatic cancer cell proliferation, invasion and increases drug-resistance through histone modification of P27, P53 and Bax

Feng Jiao, Hai Hu, Cuncun Yuan, Ziliang Jin, Zhen Guo, Liwei Wang, Lei Wang
Pages: 1523-1530
Published online on: 29 July 2014

  • View Full Article Download
Article

18F-FDG PET/CT can be used to detect non-functioning pancreatic neuroendocrine tumors

Guopei Luo, Zuqiang Liu, Meng Guo, Kaizhou Jin, Zhiwen Xiao, Liang Liu, Jin Xu, Bo Zhang, Chen Liu, Dan Huang, Silong Hu, Quanxing Ni, Jiang Long, Xianjun Yu
Pages: 1531-1536
Published online on: 29 July 2014

  • View Full Article Download
Article

miR‑222 regulates sorafenib resistance and enhance tumorigenicity in hepatocellular carcinoma Retraction in /10.3892/ijo.2021.5280

Kai Liu, Songyang Liu, Wei Zhang, Bai Ji, Yingchao Wang, Yahui Liu
Pages: 1537-1546
Published online on: 04 August 2014

  • View Full Article Download
Article

Increased CDC20 expression is associated with development and progression of hepatocellular carcinoma

Jia Li, Jian-Zhi Gao, Jing-Li Du, Zhong-Xi Huang, Li-Xin Wei
Pages: 1547-1555
Published online on: 24 July 2014

  • View Full Article Download
Article

An oligonucleotide-tagged microarray for routine diagnostics of colon cancer by genotyping KRAS mutations

Yuliang Liu, Haukur Gudnason, Yi-Ping Li, Dang Duong Bang, Anders Wolff
Pages: 1556-1564
Published online on: 11 July 2014

  • View Full Article Download
Article

Therapeutic potential of capillary morphogenesis gene 2 extracellular vWA domain in tumour‑related angiogenesis

Lin Ye, Ping-Hui Sun, Andrew J. Sanders, Tracey A. Martin, Jane Lane, Malcolm D. Mason, Wen G. Jiang
Pages: 1565-1573
Published online on: 03 July 2014

  • View Full Article Download
Article

BTG1 expression in thyroid carcinoma: Diagnostic indicator and prognostic marker

Y. F. Lu, G. G. Sun, Q. Liu, C. R. Yang, Y. J. Cheng
Pages: 1574-1582
Published online on: 11 July 2014

  • View Full Article Download
Article

Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity

Susumu Nakata, Harunari Tanaka, Yuichi Ito, Masayasu Hara, Mitsugu Fujita, Eisaku Kondo, Yukihide Kanemitsu, Yasushi Yatabe, Hayao Nakanishi
Pages: 1583-1593
Published online on: 08 July 2014

  • View Full Article Download
Article

USP22 promotes the G1/S phase transition by upregulating FoxM1 expression via β-catenin nuclear localization and is associated with poor prognosis in stage II pancreatic ductal adenocarcinoma

Zhen Ning, Aman Wang, Jinxiao Liang, Yunpeng Xie, Jiwei Liu, Lu Feng, Qiu Yan, Zhongyu Wang
Pages: 1594-1608
Published online on: 03 July 2014

  • View Full Article Download
Article

Inhibition of activated Ras suppresses multiple oncogenic Hub genes in human epithelial tumors

Lei Cao, Ping Wang, Hui Luo, Xi-Rui Wang, Xie-Feng Wang, Jun-Xia Zhang, Ying-Yi Wang, Lei Yao, Ning Liu, Yong-Ping You
Pages: 1609-1617
Published online on: 03 July 2014

  • Download
Article

Altered microRNA expression profiles are involved in resistance to low-dose ionizing radiation in the absence of BMI1 in human dermal fibroblasts

Seunghee Bae, Karam Kim, Hwa Jun Cha, Yeongmin Choi, Shang Hun Shin, In-Sook An, Jae Ho Lee, Jie-Young Song, Kwang Hee Yang, Seon Young Nam, Sungkwan An
Pages: 1618-1628
Published online on: 11 July 2014

  • View Full Article Download
Article

Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB‑231 partly through suppression of the Akt pathway

Hana Jin, Won Sup Lee, So Young Eun, Ji Hyun Jung, Hyeon-Soo Park, Gonsup Kim, Yung Hyun Choi, Chung Ho Ryu, Jin Myung Jung, Soon Chan Hong, Sung Chul Shin, Hye Jung Kim
Pages: 1629-1637
Published online on: 04 July 2014

  • View Full Article Download
Article

Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/β-catenin pathway

Qian Sun, Ronghua Wang, Jing Luo, Peng Wang, Si Xiong, Man Liu, Bin Cheng
Pages: 1638-1648
Published online on: 07 July 2014

  • View Full Article Download
Article

Silencing of CXCR7 gene represses growth and invasion and induces apoptosis in colorectal cancer through ERK and β-arrestin pathways

Xin-Xiang Li, Hong-Tu Zheng, Li-Yong Huang, De-Bing Shi, Jun-Jie Peng, Lei Liang, San-Jun Cai
Pages: 1649-1657
Published online on: 21 July 2014

  • View Full Article Download
Article

The neurokinin-1 receptor antagonist aprepitant is a promising candidate for the treatment of breast cancer

Miguel Muñoz, Ana González-Ortega, Manuel Vicente Salinas-Martín, Andrés Carranza, Susana Garcia-Recio, Vanessa Almendro, Rafael Coveñas
Pages: 1658-1672
Published online on: 28 July 2014

  • View Full Article Download
Article

Torilis japonica extract, a new potential EMT suppressor agent by regulation of EGFR signaling pathways

Guen Tae Kim, Se Hee Lee, Young Min Kim
Pages: 1673-1679
Published online on: 17 July 2014

  • View Full Article Download
Article

BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L)

Ji Hoon Jang, Yoon Chul Cho, Ki Ho Kim, Kyung Seop Lee, Jinho Lee, Dong Eun Kim, Jun-Soo Park, Byeong-Churl Jang, Shin Kim, Taeg Kyu Kwon, Jong-Wook Park
Pages: 1680-1690
Published online on: 04 July 2014

  • View Full Article Download
Article

Auranofin displays anticancer activity against ovarian cancer cells through FOXO3 activation independent of p53

See-Hyoung Park, Jung Han Lee, Jonathan S. Berek, Mickey C.-T. Hu
Pages: 1691-1698
Published online on: 04 August 2014

  • View Full Article Download
Article

The cytoplasmic domain of N-cadherin modulates MMP‑9 induction in oral squamous carcinoma cells

Andrew Walker, Rhett Frei, Kathryn R. Lawson
Pages: 1699-1706
Published online on: 21 July 2014

  • View Full Article Download
Article

Protein kinase C-associated kinase regulates NF-κB activation through inducing IKK activation

Sang-Woo Kim, Matthew Schifano, David Oleksyn, Craig T. Jordan, Daniel Ryan, Richard Insel, Jiyong Zhao, Luojing Chen
Pages: 1707-1714
Published online on: 04 August 2014

  • View Full Article Download
Article

Histone deacetylase inhibitors induce attenuation of Wnt signaling and TCF7L2 depletion in colorectal carcinoma cells

Silke Götze, Monique Coersmeyer, Oliver Müller, Sonja Sievers
Pages: 1715-1723
Published online on: 21 July 2014

  • View Full Article Download
Article

Evaluation of meisoindigo, an indirubin derivative: in vitro antileukemic activity and in vivo pharmacokinetics

Meng Huang, Hai-Shu Lin, Ying Shiuan Lee, Paul C. Ho
Pages: 1724-1734
Published online on: 21 July 2014

  • View Full Article Download
Article

Ubiquitin-proteasomal degradation of antiapoptotic survivin facilitates induction of apoptosis in prostate cancer cells by pristimerin

Yong Bo Liu, Xiaohua Gao, Dorrah Deeb, Chris Brigolin, Yiguan Zhang, Jiajiu Shaw, Kirit Pindolia, Subhash C. Gautam
Pages: 1735-1741
Published online on: 25 July 2014

  • View Full Article Download
Article

Mechanisms and potential molecular markers of early response to combination epigenetic therapy in patients with myeloid malignancies

H. B. Liu, D. Urbanavicius, P. Tan, A. Spencer, A. E. Dear
Pages: 1742-1748
Published online on: 22 July 2014

  • View Full Article Download
Article

Cytotoxic effects of pyrrolidine dithiocarbamate in small-cell lung cancer cells, alone and in combination with cisplatin

Shinichi Tahata, Bo Yuan, Hidetomo Kikuchi, Norio Takagi, Toshihiko Hirano, Hiroo Toyoda
Pages: 1749-1759
Published online on: 28 July 2014

  • View Full Article Download
Article

Cadmium induces urokinase-type plasminogen activator receptor expression and the cell invasiveness of human gastric cancer cells via the ERK-1/2, NF-κB, and AP-1 signaling pathways

Pham Ngoc Khoi, Yong Xia, Sen Lian, Ho Dong Kim, Do Hyun Kim, Young Eun Joo, Kee-Oh Chay, Kyung Keun Kim, Young Do Jung
Pages: 1760-1768
Published online on: 22 July 2014

  • View Full Article Download
Article

Enhanced apoptosis by pemetrexed and simvastatin in malignant mesothelioma and lung cancer cells by reactive oxygen species-dependent mitochondrial dysfunction and Bim induction

Ki-Eun Hwang, Young-Suk Kim, Yu-Ri Hwang, Su-Jin Kwon, Do-Sim Park, Byong-Ki Cha, Byoung-Ryun Kim, Kwon-Ha Yoon, Eun-Taik Jeong, Hak-Ryul Kim
Pages: 1769-1777
Published online on: 05 August 2014

  • View Full Article Download
Journal Cover
January-2026 Volume 68 Issue 1

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

  • View Full Article Download
Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

  • View Full Article Download
Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

  • View Full Article Download
Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

  • View Full Article Download
Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

  • View Full Article Download
Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

  • View Full Article Download
Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

  • View Full Article Download
Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

  • View Full Article Download
Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

  • View Full Article Download
Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

  • View Full Article Download
Journal Cover
February-2026 Volume 68 Issue 2

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

  • Download
Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

  • Download
Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

  • Purchase Download
Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

  • Download
Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

  • Download
Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

  • Download
Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

  • Download
Select a topic from the Information tab...
Special issues coming soon...
No data
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team