|
1
|
Grassmann S, Sadek B, Ligneau X, et al:
Progress in the proxifan class: heterocyclic congeners as novel
potent and selective histamine H(3)-receptor antagonists. Eur J
Pharm Sci. 15:367–378. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Labanauskas L, Brukstus A, Udrenaite E,
Gaidelis P, Bucinskaite V and Dauksas V: Synthesis of
6,7-dialkoxy-2-arylmethylidene-2,3-dihydrobenzo[4,5]imidazo[2,1-b][1,3]thiazol-3-ones
exhibiting anti-inflammatory activity. Pharmazie. 55:429–431.
2000.PubMed/NCBI
|
|
3
|
Sevak R, Paul A, Goswami S and Santani D:
Gastroprotective effect of beta3 adrenoreceptor agonists ZD 7114
and CGP 12177A in rats. Pharmacol Res. 46:351–356. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Can-Eke B, Puskullu MO, Buyukbingol E and
Iscan M: A study on the antioxidant capacities of some
benzimidazoles in rat tissues. Chem Biol Interact. 113:65–77. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Hoskin PJ, Saunders MI and Dische S:
Hypoxic radiosensitizers in radical radiotherapy for patients with
bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated
radiotherapy, carbogen, and nicotinamide. Cancer. 86:1322–1328.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Brown JM: The hypoxic cell: a target for
selective cancer therapy - eighteenth Bruce F. Cain Memorial Award
lecture. Cancer Res. 59:5863–5870. 1999.PubMed/NCBI
|
|
7
|
Baviskar AT, Madaan C, Preet R, et al:
N-fused imidazoles as novel anticancer agents that inhibit
catalytic activity of topoisomerase IIalpha and induce apoptosis in
G1/S phase. J Med Chem. 54:5013–5030. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Gunther W, Pawlak E, Damasceno R, Arnold H
and Terzis AJ: Temozolomide induces apoptosis and senescence in
glioma cells cultured as multicellular spheroids. Br J Cancer.
88:463–469. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Levine B and Klionsky DJ: Development by
self-digestion: molecular mechanisms and biological functions of
autophagy. Dev Cell. 6:463–477. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Mizushima N, Levine B, Cuervo AM and
Klionsky DJ: Autophagy fights disease through cellular
self-digestion. Nature. 451:1069–1075. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Rubinsztein DC, Gestwicki JE, Murphy LO
and Klionsky DJ: Potential therapeutic applications of autophagy.
Nat Rev Drug Discov. 6:304–312. 2007. View
Article : Google Scholar : PubMed/NCBI
|
|
12
|
Lum JJ, Bauer DE, Kong M, et al: Growth
factor regulation of autophagy and cell survival in the absence of
apoptosis. Cell. 120:237–248. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Degenhardt K, Mathew R, Beaudoin B, et al:
Autophagy promotes tumor cell survival and restricts necrosis,
inflammation, and tumorigenesis. Cancer Cell. 10:51–64. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Paglin S, Hollister T, Delohery T, et al:
A novel response of cancer cells to radiation involves autophagy
and formation of acidic vesicles. Cancer Res. 61:439–444.
2001.PubMed/NCBI
|
|
15
|
Kanzawa T, Germano IM, Komata T, Ito H,
Kondo Y and Kondo S: Role of autophagy in temozolomide-induced
cytotoxicity for malignant glioma cells. Cell Death Differ.
11:448–457. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Gorka M, Daniewski WM, Gajkowska B,
Lusakowska E, Godlewski MM and Motyl T: Autophagy is the dominant
type of programmed cell death in breast cancer MCF-7 cells exposed
to AGS 115 and EFDAC, new sesquiterpene analogs of paclitaxel.
Anticancer Drugs. 16:777–788. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Apel A, Herr I, Schwarz H, Rodemann HP and
Mayer A: Blocked autophagy sensitizes resistant carcinoma cells to
radiation therapy. Cancer Res. 68:1485–1494. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Mizushima N: Autophagy: process and
function. Genes Dev. 21:2861–2873. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Ohkuma S and Poole B: Cytoplasmic
vacuolation of mouse peritoneal macrophages and the uptake into
lysosomes of weakly basic substances. J Cell Biol. 90:656–664.
1981. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Cotter TG: Apoptosis and cancer: the
genesis of a research field. Nat Rev Cancer. 9:501–507. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Bold RJ, Termuhlen PM and McConkey DJ:
Apoptosis, cancer and cancer therapy. Surg Oncol. 6:133–142. 1997.
View Article : Google Scholar
|
|
22
|
Strasser A: The role of BH3-only proteins
in the immune system. Nat Rev Immunol. 5:189–200. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Bouillet P and Strasser A: BH3-only
proteins - evolutionarily conserved proapoptotic Bcl-2 family
members essential for initiating programmed cell death. J Cell Sci.
115:1567–1574. 2002.PubMed/NCBI
|
|
24
|
Akiyama T, Dass CR and Choong PF:
Bim-targeted cancer therapy: a link between drug action and
underlying molecular changes. Mol Cancer Ther. 8:3173–3180. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Ren D, Tu HC, Kim H, et al: BID, BIM, and
PUMA are essential for activation of the BAX- and BAK-dependent
cell death program. Science. 330:1390–1393. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Simpson CD, Anyiwe K and Schimmer AD:
Anoikis resistance and tumor metastasis. Cancer Lett. 272:177–185.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Uehara N, Matsuoka Y and Tsubura A:
Mesothelin promotes anchorage-independent growth and prevents
anoikis via extracellular signal-regulated kinase signaling pathway
in human breast cancer cells. Mol Cancer Res. 6:186–193. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Woods NT, Yamaguchi H, Lee FY, Bhalla KN
and Wang HG: Anoikis, initiated by Mcl-1 degradation and Bim
induction, is deregulated during oncogenesis. Cancer Res.
67:10744–10752. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Iguchi K, Usui S, Ishida R and Hirano K:
Imidazole-induced cell death, associated with intracellular
acidification, caspase-3 activation, DFF-45 cleavage, but not
oligonucleosomal DNA fragmentation. Apoptosis. 7:519–525. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Denizot F and Lang R: Rapid colorimetric
assay for cell growth and survival. Modifications to the
tetrazolium dye procedure giving improved sensitivity and
reliability. J Immunol Methods. 89:271–277. 1986. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Mizushima N, Yoshimori T and Levine B:
Methods in mammalian autophagy research. Cell. 140:313–326. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Su M, Mei Y and Sinha S: Role of the
crosstalk between autophagy and apoptosis in cancer. J Oncol.
2013:1027352013. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Yang ZJ, Chee CE, Huang S and Sinicrope
FA: The role of autophagy in cancer: therapeutic implications. Mol
Cancer Ther. 10:1533–1541. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Sridharan S, Jain K and Basu A: Regulation
of autophagy by kinases. Cancers (Basel). 3:2630–2654. 2011.
View Article : Google Scholar
|
|
35
|
Sinha S and Levine B: The autophagy
effector Beclin 1: a novel BH3-only protein. Oncogene. 27(Suppl 1):
S137–S148. 2008. View Article : Google Scholar
|
|
36
|
Corcelle E, Djerbi N, Mari M, et al:
Control of the autophagy maturation step by the MAPK ERK and p38:
lessons from environmental carcinogens. Autophagy. 3:57–59. 2007.
View Article : Google Scholar
|
|
37
|
Geng Y, Kohli L, Klocke BJ and Roth KA:
Chloroquine-induced autophagic vacuole accumulation and cell death
in glioma cells is p53 independent. Neuro Oncol. 12:473–481.
2010.PubMed/NCBI
|
|
38
|
Wang Z, Zhang J, Wang Y, et al: Matrine, a
novel autophagy inhibitor, blocks trafficking and the proteolytic
activation of lysosomal proteases. Carcinogenesis. 34:128–138.
2013. View Article : Google Scholar
|
|
39
|
Poole B and Ohkuma S: Effect of weak bases
on the intralysosomal pH in mouse peritoneal macrophages. J Cell
Biol. 90:665–669. 1981. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Krezel I: New derivatives of imidazole as
potential anticancer agents. Farmaco. 53:342–345. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Gonzalez-Polo RA, Boya P, Pauleau AL, et
al: The apoptosis/ autophagy paradox: autophagic vacuolization
before apoptotic death. J Cell Sci. 118:3091–3102. 2005. View Article : Google Scholar
|
|
42
|
Boya P, Gonzalez-Polo RA, Casares N, et
al: Inhibition of macro-autophagy triggers apoptosis. Mol Cell
Biol. 25:1025–1040. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Yamamoto A, Tagawa Y, Yoshimori T,
Moriyama Y, Masaki R and Tashiro Y: Bafilomycin A1 prevents
maturation of autophagic vacuoles by inhibiting fusion between
autophagosomes and lysosomes in rat hepatoma cell line, H-4-II-E
cells. Cell Struct Funct. 23:33–42. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Zanella F, Link W and Carnero A:
Understanding FOXO, new views on old transcription factors. Curr
Cancer Drug Targets. 10:135–146. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Kawamura N, Kugimiya F, Oshima Y, et al:
Akt1 in osteoblasts and osteoclasts controls bone remodeling. PLoS
One. 2:e10582007. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Barreyro FJ, Kobayashi S, Bronk SF,
Werneburg NW, Malhi H and Gores GJ: Transcriptional regulation of
Bim by FoxO3A mediates hepatocyte lipoapoptosis. J Biol Chem.
282:27141–27154. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Gilley J, Coffer PJ and Ham J: FOXO
transcription factors directly activate bim gene expression and
promote apoptosis in sympathetic neurons. J Cell Biol. 162:613–622.
2003. View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Sunters A, Fernandez de Mattos S, Stahl M,
et al: FoxO3a transcriptional regulation of Bim controls apoptosis
in paclitaxel-treated breast cancer cell lines. J Biol Chem.
278:49795–49805. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Carbajo-Pescador S, Steinmetz C, Kashyap
A, et al: Melatonin induces transcriptional regulation of Bim by
FoxO3a in HepG2 cells. Br J Cancer. 108:442–449. 2013. View Article : Google Scholar :
|
