|
1
|
Gabrilovich D: Mechanisms and functional
significance of tumour-induced dendritic-cell defects. Nat Rev
Immunol. 4:941–952. 2004. View
Article : Google Scholar : PubMed/NCBI
|
|
2
|
Fang DD, Kim YJ, Lee CN, et al: Expansion
of CD133 (+) colon cancer cultures retaining stem cell properties
to enable cancer stem cell target discovery. Br J Cancer.
102:1265–1275. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Dick JE: Stem cell concepts renew cancer
research. Blood. 112:4793–4807. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Sukach AN and Ivanov EN: Formation of
spherical colonies as a property of stem cells. Tsitologiia.
49:916–922. 2007.(In Russian).
|
|
5
|
Singh SK, Clarke ID, Terasaki M, Bonn VE,
Hawkins C, Squire J and Dirks PB: Identification of a cancer stem
cell in human brain tumors. Cancer Res. 63:5821–5828.
2003.PubMed/NCBI
|
|
6
|
Farnie G, Clarke RB, Spence K, Pinnock N,
Brennan K, Anderson NG and Bundred NJ: Novel cell culture technique
for primary ductal carcinoma in situ: role of Notch and epidermal
growth factor receptor signaling pathways. J Natl Cancer Inst.
99:616–627. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Vermeulen L, Todaro M, de Sousa Mello F,
Sprick MR, Kemper K, Perez Alea M, Richel DJ, Stassi G and Medema
JP: Single-cell cloning of colon cancer stem cells reveals a
multi-lineage differentiation capacity. Proc Natl Acad Sci USA.
105:13427–13432. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
van der Flier LG, van Gijn ME, Hatzis P,
et al: Transcription factor achaetescute-like 2 controls intestinal
stem cell fate. Cell. 136:903–912. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Barker N, van Es JH, Kuipers J, et al:
Identification of stem cells in small intestine and colon by marker
gene Lgr5. Nature. 449:1003–1007. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Leng Z, Tao K, Xia Q, Tan J, Yue Z, Chen
J, Xi H, Li J and Zheng H: Kruppel-like factor 4 acts as an
oncogene in colon cancer stem cell-enriched spheroid cells. PLoS
One. 8:e560822013. View Article : Google Scholar
|
|
11
|
Sangiorgi E and Capecchi MR: Bmi1 is
expressed in vivo in intestinal stem cells. Nat Genet. 40:915–920.
2008. View
Article : Google Scholar : PubMed/NCBI
|
|
12
|
Wen K, Fu Z, Wu X, Feng J, Chen W and Qian
J: Oct-4 is required for an antiapoptotic behavior of
chemoresistant colorectal cancer cells enriched for cancer stem
cells: effects associated with STAT3/Survivin. Cancer Lett.
333:56–65. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Takahashi K, Tanabe K, Ohnuki M, Narita M,
Ichisaka T, Tomoda K and Yamanaka S: Induction of pluripotent stem
cells from adult human fibroblasts by defined factors. Cell.
131:861–872. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Ishihara K and Hirano T: IL-6 in
autoimmune disease and chronic inflammatory proliferative disease.
Cytokine Growth Factor Rev. 13:357–368. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Nian M, Lee P, Khaper N and Liu P:
Inflammatory cytokines and postmyocardial infarction remodeling.
Circ Res. 94:1543–1553. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Wu CW, Wang SR, Chao MF, Wu TC, Lui WY,
P’eng FK and Chi CW: Serum interleukin-6 levels reflect disease
status of gastric cancer. Am J Gastroenterol. 91:1417–1422.
1996.PubMed/NCBI
|
|
17
|
Koontongkaew S, Amornphimoltham P and
Yapong B: Tumor-stroma interactions influence cytokine expression
and matrix metalloproteinase activities in paired primary and
metastatic head and neck cancer cells. Cell Biol Int. 33:165–173.
2009. View Article : Google Scholar
|
|
18
|
Burger RA, Grosen EA, Ioli GR, et al:
Spontaneous release of interleukin-6 by primary cultures of
lymphoid and tumor cell populations purified from human ovarian
carcinoma. J Interferon Cytokine Res. 15:255–260. 1995. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Knupfer H and Preiss R: Serum
interleukin-6 levels in colorectal cancer patients - a summary of
published results. Int J Colorectal Dis. 25:135–140. 2010.
View Article : Google Scholar
|
|
20
|
Hsu CP and Chung YC: Influence of
interleukin-6 on the invasiveness of human colorectal carcinoma.
Anticancer Res. 26:4607–4614. 2006.
|
|
21
|
Corvinus FM, Orth C, Moriggl R, et al:
Persistent STAT3 activation in colon cancer is associated with
enhanced cell proliferation and tumor growth. Neoplasia. 7:545–555.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Lin L, Fuchs J, Li C, Olson V, Bekaii-Saab
T and Lin J: STAT3 signaling pathway is necessary for cell survival
and tumor sphere forming capacity in ALDH(+)/CD133(+) stem
cell-like human colon cancer cells. Biochem Biophys Res Commun.
416:246–251. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Cheng X, Jin G, Zhang X, Tian M and Zou L:
Stage-dependent STAT3 activation is involved in the differentiation
of rat hippocampus neural stem cells. Neurosci Lett. 493:18–23.
2011. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Luo Y, Mughal MR, Ouyang TG, Jiang H, Luo
W, Yu QS, Greig NH and Mattson MP: Plumbagin promotes the
generation of astrocytes from rat spinal cord neural progenitors
via activation of the transcription factor Stat3. J Neurochem.
115:1337–1349. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Sansone P, Storci G, Tavolari S, et al:
IL-6 triggers malignant features in mammospheres from human ductal
breast carcinoma and normal mammary gland. J Clin Invest.
117:3988–4002. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Fan X, Matsui W, Khaki L, Stearn D, Chun
J, Li YM and Eberhart CG: Notch pathway inhibition depletes
stem-like cells and blocks engraftment in embryonal brain tumors.
Cancer Res. 66:7445–7452. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Fan X, Ouyang N, Teng H and Yao H:
Isolation and characterization of spheroid cells from the HT29
colon cancer cell line. Int J Colorectal Dis. 26:1279–1285. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Fletcher JI, Haber M, Henderson MJ and
Norris MD: ABC transporters in cancer: more than just drug efflux
pumps. Nat Rev Cancer. 10:147–156. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Olszewski WL, Kubicka U, Tarnowski W,
Bielecki K, Ziolkowska A and Wesolowska A: Activation of human
peritoneal immune cells in early stages of gastric and colon
cancer. Surgery. 141:212–221. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Lin L, Liu A, Peng Z, Lin HJ, Li PK, Li
PK, Li C and Lin J: STAT3 is necessary for proliferation and
survival in colon cancer-initiating cells. Cancer Res.
71:7226–7237. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Bruce WR and van der Gaag H: A
quantitative assay for the number of murine lymphoma cells capable
of proliferation in vivo. Nature. 199:79–80. 1963. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Willson JK, Bittner GN, Oberley TD,
Meisner LF and Weese JL: Cell culture of human colon adenomas and
carcinomas. Cancer Res. 47:2704–2713. 1987.PubMed/NCBI
|
|
33
|
Singh SK, Hawkins C, Clarke ID, Squire JA,
Bayani J, Hide T, Henkelman RM, Cusimano MD and Dirks PB:
Identification of human brain tumour initiating cells. Nature.
432:396–401. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Dey D, Saxena M, Paranjape AN, Krishnan V,
Giraddi R, Kumar MV, Mukherjee G and Rangarajan A: Phenotypic and
functional characterization of human mammary stem/progenitor cells
in long term culture. PLoS One. 4:e53292009. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Todaro M, Alea MP, Di Stefano AB, et al:
Colon cancer stem cells dictate tumor growth and resist cell death
by production of interleukin-4. Cell Stem Cell. 1:389–402. 2007.
View Article : Google Scholar
|
|
36
|
Lopez J, Poitevin A, Mendoza-Martinez V,
Perez-Plasencia C and Garcia-Carranca A: Cancer-initiating cells
derived from established cervical cell lines exhibit stem-cell
markers and increased radioresistance. BMC Cancer. 12:482012.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Christgen M, Ballmaier M, Bruchhardt H,
von Wasielewski R, Kreipe H and Lehmann U: Identification of a
distinct side population of cancer cells in the Cal-51 human breast
carcinoma cell line. Mol Cell Biochem. 306:201–212. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Han B and Zhang JT: Multidrug resistance
in cancer chemotherapy and xenobiotic protection mediated by the
half ATP-binding cassette transporter ABCG2. Curr Med Chem
Anticancer Agents. 4:31–42. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Lichtenauer UD, Shapiro I, Osswald A,
Meurer S, Kulle A, Reincke M, Riepe F and Beuschlein F:
Characterization of NCI-H295R cells as an in vitro model of
hyperaldosteronism. Horm Metab Res. 45:124–129. 2013.
|
|
40
|
Gabriel E, Schievenbusch S, Kolossov E,
Hengstler JG, Rotshteyn T, Bohlen H, Nierhoff D, Hescheler J and
Drobinskaya L: Differentiation and selection of hepatocyte
precursors in suspension spheroid culture of transgenic murine
embryonic stem cells. PLoS One. 7:e449122012. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Ohata H, Ishiguro T, Aihara Y, et al:
Induction of the stem-like cell regulator CD44 by Rho kinase
inhibition contributes to the maintenance of colon
cancer-initiating cells. Cancer Res. 72:5101–5110. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
42
|
Scheller J and Rose-John S: Interleukin-6
and its receptor: from bench to bedside. Med Microbiol Immunol.
195:173–183. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Fisman EZ and Tenenbaum A: The ubiquitous
interleukin-6: a time for reappraisal. Cardiovasc Diabetol.
9:622010. View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Yi H, Cho HJ, Cho SM, Jo K, Park JA, Lee
SH, Chang BJ, Kim JS and Shin HC: Effect of 5-FU and MTX on the
expression of drug-resistance related cancer stem cell markers in
nn-small cell lung cancer cells. Korean J Physiol Pharmacol.
16:11–16. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
45
|
Conze D, Weiss L, Regen PS, Bhushan A,
Weaver D, Johnson P and Rincon M: Autocrine production of
interleukin 6 causes multidrug resistance in breast cancer cells.
Cancer Res. 61:8851–8858. 2001.PubMed/NCBI
|
|
46
|
Kim SY, Kang JW, Song X, Kim BK, Yoo YD,
Kwon YT and Lee YJ: Role of the IL-6-JAK1-STAT3-Oct-4 pathway in
the conversion of non-stem cancer cells into cancer stem-like
cells. Cell Signal. 25:961–969. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Garzia L, Andolfo I, Cusanelli E, et al:
MicroRNA-199b-5p impairs cancer stem cells through negative
regulation of HES1 in medulloblastoma. PLoS One. 4:e49982009.
View Article : Google Scholar : PubMed/NCBI
|
|
48
|
Wang Z, Li Y, Kong D, et al: Acquisition
of epithelial-mesenchymal transition phenotype of
gemcitabine-resistant pancreatic cancer cells is linked with
activation of the notch signaling pathway. Cancer Res.
69:2400–2407. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
49
|
Levina V, Marrangoni AM, DeMarco R,
Gorelik E and Lokshin AE: Drug-selected human lung cancer stem
cells: cytokine network, tumorigenic and metastatic properties.
PLoS One. 3:e30772008. View Article : Google Scholar : PubMed/NCBI
|
|
50
|
Bao B, Ali S, Ahmad A, et al:
Hypoxia-induced aggressiveness of pancreatic cancer cells is due to
increased expression of VEGF, IL-6 and miR-21, which can be
attenuated by CDF treatment. PLoS One. 7:e501652012. View Article : Google Scholar : PubMed/NCBI
|
|
51
|
Grivennikov S and Karin M: Autocrine IL-6
signaling: a key event in tumorigenesis? Cancer Cell. 13:7–9. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
52
|
Radtke F and Raj K: The role of Notch in
tumorigenesis: oncogene or tumour suppressor? Nat Rev Cancer.
3:756–767. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
53
|
Leong KG and Karsan A: Recent insights
into the role of Notch signaling in tumorigenesis. Blood.
107:2223–2233. 2006. View Article : Google Scholar
|
|
54
|
Reedijk M, Odorcic S, Zhang H, Chetty R,
Tennert C, Dickson BC, Lockwood G, Gallinger S and Egan SE:
Activation of Notch signaling in human colon adenocarcinoma. Int J
Oncol. 33:1223–1229. 2008.PubMed/NCBI
|
|
55
|
Zhang H, Li W, Nan F, Ren F, Wang H, Xu Y
and Zhang F: MicroRNA expression profile of colon cancer stem-like
cells in HT29 adenocarcinoma cell line. Biochem and Biophys Res
Commun. 404:273–278. 2011. View Article : Google Scholar
|
|
56
|
Sullivan JP, Spinola M, Dodge M, et al:
Aldehyde dehydrogenase activity selects for lung adenocarcinoma
stem cells dependent on notch signaling. Cancer Res. 70:9937–9948.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
57
|
McAuliffe SM, Morgan SL, Wyant GA, et al:
Targeting Notch, a key pathway for ovarian cancer stem cells,
sensitizes tumors to platinum therapy. Proc Natl Acad Sci USA.
109:E2939–E2948. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
58
|
Ma XT, Wang S, Ye YJ, Du RY, Cui ZR and
Somsouk M: Constitutive activation of Stat3 signaling pathway in
human colorectal carcinoma. World J Gastroenterol. 10:1569–1573.
2004.PubMed/NCBI
|
|
59
|
Ashizawa T, Miyata H, Iizuka A, et al:
Effect of the STAT3 inhibitor STX-0119 on the proliferation of
cancer stem-like cells derived from recurrent glioblastoma. Int J
Oncol. 43:219–227. 2013.PubMed/NCBI
|
|
60
|
Song X, Wang M, Zhang L, Zhang J, Wang X,
Lui W, Gu X and Lv C: Changes in cell ultrastructure and inhibition
of JAK1/STAT3 signaling pathway in CBRH-7919 cells with
astaxanthin. Toxicol Mech Methods. 22:679–686. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
61
|
Lin Q, Lai R, Chirieac LR, et al:
Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and
cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis
and cell cycle arrest of colon carcinoma cells. Am J Pathol.
167:969–980. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
62
|
Decker T and Kovarik P: Serine
phosphorylation of STATs. Oncogene. 19:2628–2637. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
63
|
Wen Z, Zhong Z and Darnell JE Jr: Maximal
activation of transcription by Stat1 and Stat3 requires both
tyrosine and serine phosphorylation. Cell. 82:241–250. 1995.
View Article : Google Scholar : PubMed/NCBI
|
|
64
|
Takaoka A, Tanaka N, Mitani Y, et al:
protein tyrosine kinase Pyk2 mediates the Jak-dependent activation
of MAPK and Stat1 in IFN-gamma, bu not IFN-alpha, signaling. EMBO
J. 18:2480–2488. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
65
|
Coppo P, Dusanter-Fourt I, Millot G, et
al: Constitutive and specific activation of STAT3 by BCR-ABL in
embryonic stem cells. Oncogene. 22:4102–4110. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
66
|
Zhang Y, Liu G and Dong Z: MSK1 and JNKs
mediate phosphorylation of STAT3 in UVA-irradiated mouse epidermal
JB6 cells. J Biol Chem. 276:42534–42542. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
67
|
Lim CP and Cao X: Serine phosphorylation
and negative regulation of Stat3 by JNK. J Biol Chem.
274:31055–31061. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
68
|
Ceresa BP and Pessin JE: Insulin
stimulates the serine phosphorylation of the signal transducer and
activator of transcription (STAT3) isoform. J Biol Chem.
271:12121–12124. 1996. View Article : Google Scholar : PubMed/NCBI
|
|
69
|
Ceresa BP, Horvath CM and Pessin JE:
Signal transducer and activator of transcription-3 serine
phosphorylation by insulin is mediated by a Ras/Raf/MEK-dependent
pathway. Endocrinology. 138:4131–4137. 1997.PubMed/NCBI
|
|
70
|
Androutsellis-Theotokis A, Leker RR,
Soldner F, et al: Notch signaling regulates stem cell numbers in
vitro and in vivo. Nature. 442:823–826. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
71
|
Nagao M, Sugimori M and Nakafuku M: Cross
talk between notch and growth factor/cytokine signaling pathways in
neural stem cells. Mol Cell Biol. 27:3982–3994. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
72
|
Rajan P and Mckay RD: Multiple routes to
astrocytic differentiation in the CNS. J Neurosci. 18:3620–3629.
1998.PubMed/NCBI
|
|
73
|
Kwak YD, Dantuma E, Merchant S, Bushnev S
and Sugaya K: Amyloid-beta precursor protein induces glial
differentiation of neural progenitor cells by activation of the
IL-6/gp130 signaling pathway. Neurotox Res. 18:328–338. 2010.
View Article : Google Scholar : PubMed/NCBI
|
|
74
|
Peng H, Sun L, Jia B, Lan X, Zhu B, Wu Y
and Zheng J: HIV-1-infected and immune-activated macrophages induce
astrocytic differentiation of human cortical neural progenitor
cells via the STAT3 pathway. PLoS One. 6:e194392011. View Article : Google Scholar : PubMed/NCBI
|
|
75
|
Luo M and Liu Z, Chen G, Hao H, Lu T, Cui
Y, Lei M, Verfaillie CM and Liu Z: High glucose enhances TGF-beta1
expression in rat bone marrow stem cells via ERK1/2-mediated
inhibition of STAT3 signaling. Life Sci. 90:509–518. 2012.
View Article : Google Scholar : PubMed/NCBI
|
|
76
|
Yoshimatsu T, Kawaguchi D, Oishi K, Takeda
K, Akira S, Masuyama N and Gotoh Y: Non-cell-autonomous action of
STAT3 in maintenance of neural precursor cells in the mouse
neocortex. Development. 133:2553–2563. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
77
|
Choi B, Chun E, Kim SY, Kim M, Lee KY and
Kim SJ: Notch-induced hIL-6 production facilitates the maintenance
of self-renewal of hCD34+ cord blood cells through the
activation of Jak-PI3K-STAT3 pathway. Am J Pathol. 180:351–364.
2012. View Article : Google Scholar
|
|
78
|
De la Iglesia N, Puram SV and Bonni A:
STAT3 regulation of glioblastoma pathogenesis. Curr Mol Med.
9:580–590. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
79
|
Kondo J, Endo H, Okuyama H, Ishikawa O,
Lishi H, Tsujii M, Ohue M and Inoue M: Retaining cell-cell contact
enables preparation and culture of spheroids composed of pure
primary cancer cells from colorectal cancer. Proc Natl Acad Sci
USA. 108:6235–6240. 2011. View Article : Google Scholar : PubMed/NCBI
|
