|
1
|
Akasaka T, Tsujii M, Kondo J, Hayashi Y,
Ying J, Lu Y, Kato M, Yamada T, Yamamoto S, Inoue T, et al: 5-FU
resistance abrogates the amplified cytotoxic effects induced by
inhibiting checkpoint kinase 1 in p53-mutated colon cancer cells.
Int J Oncol. 46:63–70. 2015.
|
|
2
|
Qi Q, You Q, Gu H, Zhao L, Liu W, Lu N and
Guo Q: Studies on the toxicity of gambogic acid in rats. J
Ethnopharmacol. 117:433–438. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Shi X, Chen X, Li X, Lan X, Zhao C, Liu S,
Huang H, Liu N, Liao S, Song W, et al: Gambogic acid induces
apoptosis in imatinib-resistant chronic myeloid leukemia cells via
inducing proteasome inhibition and caspase-dependent Bcr-Abl
down-regulation. Clin Cancer Res. 20:151–163. 2014. View Article : Google Scholar :
|
|
4
|
Chuah LO, Yeap SK, Ho WY, Beh BK and
Alitheen NB: In vitro and in vivo toxicity of garcinia or
hydroxycitric Acid: A review. Evid Based Complement Alternat Med.
2012:1979.202012.
|
|
5
|
Márquez F, Babio N, Bulló M and
Salas-Salvadó J: Evaluation of the safety and efficacy of
hydroxycitric acid or Garcinia cambogia extracts in humans. Crit
Rev Food Sci Nutr. 52:585–594. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Chi Y, Zhan XK, Yu H, Xie GR, Wang ZZ,
Xiao W, Wang YG, Xiong FX, Hu JF, Yang L, et al: An open-labeled,
randomized, multicenter phase IIa study of gambogic acid injection
for advanced malignant tumors. Chin Med J (Engl). 126:1642–1646.
2013.
|
|
7
|
Wang LH, Yang JY, Yang SN, Li Y, Ping GF,
Hou Y, Cui W, Wang ZZ, Xiao W and Wu CF: Suppression of NF-κB
signaling and P-glycoprotein function by gambogic acid
synergistically potentiates adriamycin-induced apoptosis in lung
cancer. Curr Cancer Drug Targets. 14:91–103. 2014. View Article : Google Scholar
|
|
8
|
Li C, Qi Q, Lu N, Dai Q, Li F, Wang X, You
Q and Guo Q: Gambogic acid promotes apoptosis and resistance to
metastatic potential in MDA-MB-231 human breast carcinoma cells.
Biochem Cell Biol. 90:718–730. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Li X, Liu S, Huang H, Liu N, Zhao C, Liao
S, Yang C, Liu Y, Zhao C, Li S, et al: Gambogic acid is a
tissue-specific proteasome inhibitor in vitro and in vivo. Cell
Rep. 3:211–222. 2013. View Article : Google Scholar
|
|
10
|
Yi T, Yi Z, Cho SG, Luo J, Pandey MK,
Aggarwal BB and Liu M: Gambogic acid inhibits angiogenesis and
prostate tumor growth by suppressing vascular endothelial growth
factor receptor 2 signaling. Cancer Res. 68:1843–1850. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Song M, Chen D, Lu B, Wang C, Zhang J,
Huang L, Wang X, Timmons CL, Hu J, Liu B, et al: PTEN loss
increases PD-L1 protein expression and affects the correlation
between PD-L1 expression and clinical parameters in colorectal
cancer. PLoS One. 8:e658212013. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Shapiro GI and Harper JW: Anticancer drug
targets: Cell cycle and checkpoint control. J Clin Invest.
104:1645–1653. 1999. View
Article : Google Scholar : PubMed/NCBI
|
|
13
|
Pines J: Four-dimensional control of the
cell cycle. Nat Cell Biol. 1:E73–E79. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Evan GI and Vousden KH: Proliferation,
cell cycle and apoptosis in cancer. Nature. 411:342–348. 2001.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang X: The expanding role of mitochondria
in apoptosis. Genes Dev. 15:2922–2933. 2001.PubMed/NCBI
|
|
16
|
Tsujimoto Y: Role of Bcl-2 family proteins
in apoptosis: Apoptosomes or mitochondria? Genes Cells. 3:697–707.
1998. View Article : Google Scholar
|
|
17
|
Brenner H, Kloor M and Pox CP: Colorectal
cancer. Lancet. 383:1490–1502. 2014. View Article : Google Scholar
|
|
18
|
Temraz S, Mukherji D, Alameddine R and
Shamseddine A: Methods of overcoming treatment resistance in
colorectal cancer. Crit Rev Oncol Hematol. 89:217–230. 2014.
View Article : Google Scholar
|
|
19
|
Gustavsson B, Carlsson G, Machover D,
Petrelli N, Roth A, Schmoll HJ, Tveit KM and Gibson F: A review of
the evolution of systemic chemotherapy in the management of
colorectal cancer. Clin Colorectal Cancer. 14:1–10. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gandhi S, Fletcher GG, Eisen A, Mates M,
Freedman OC, Dent SF and Trudeau ME: Adjuvant chemotherapy for
early female breast cancer: A systematic review of the evidence for
the 2014 Cancer Care Ontario systemic therapy guideline. Curr
Oncol. 22(Suppl 1): S82–S94. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Thota R, Pauff JM and Berlin JD: Treatment
of metastatic pancreatic adenocarcinoma: A review. Oncology
(Williston Park). 28:70–74. 2014.
|
|
22
|
Johnstone RW, Ruefli AA and Lowe SW:
Apoptosis: A link between cancer genetics and chemotherapy. Cell.
108:153–164. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Krajarng A, Imoto M, Tashiro E, Fujimaki
T, Shinjo S and Watanapokasin R: Apoptosis induction associated
with the ER stress response through up-regulation of JNK in HeLa
cells by gambogic acid. BMC Complement Altern Med. 15:262015.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Zhao W, Zhou SF, Zhang ZP, Xu GP, Li XB
and Yan JL: Gambogic acid inhibits the growth of osteosarcoma cells
in vitro by inducing apoptosis and cell cycle arrest. Oncol Rep.
25:1289–1295. 2011.PubMed/NCBI
|
|
25
|
Nie F, Zhang X, Qi Q, Yang L, Yang Y, Liu
W, Lu N, Wu Z, You Q and Guo Q: Reactive oxygen species
accumulation contributes to gambogic acid-induced apoptosis in
human hepatoma SMMC-7721 cells. Toxicology. 260:60–67. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Lee PN and Ho WS: Antiproliferative
activity of gambogic acid isolated from Garcinia hanburyi in Hep3B
and Huh7 cancer cells. Oncol Rep. 29:1744–1750. 2013.PubMed/NCBI
|
|
27
|
Xu J, Zhou M, Ouyang J, Wang J, Zhang Q,
Xu Y, Xu Y, Zhang Q, Xu X and Zeng H: Gambogic acid induces
mitochondria-dependent apoptosis by modulation of Bcl-2 and Bax in
mantle cell lymphoma JeKo-1 cells. Chin J Cancer Res. 25:183–191.
2013.PubMed/NCBI
|
|
28
|
Zhao W, You CC, Zhuang JP, Zu JN, Chi ZY,
Xu GP and Yan JL: Viability inhibition effect of gambogic acid
combined with cisplatin on osteosarcoma cells via
mitochondria-independent apoptotic pathway. Mol Cell Biochem.
382:243–252. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Fang JY and Richardson BC: The MAPK
signalling pathways and colorectal cancer. Lancet Oncol. 6:322–327.
2005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Dhanasekaran DN and Reddy EP: JNK
signaling in apoptosis. Oncogene. 27:6245–6251. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Zarubin T and Han J: Activation and
signaling of the p38 MAP kinase pathway. Cell Res. 15:11–18. 2005.
View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Dunn C, Wiltshire C, MacLaren A and
Gillespie DA: Molecular mechanism and biological functions of c-Jun
N-terminal kinase signalling via the c-Jun transcription factor.
Cell Signal. 14:585–593. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Chen J, Gu HY, Lu N, Yang Y, Liu W, Qi Q,
Rong JJ, Wang XT, You QD and Guo QL: Microtubule depolymerization
and phosphorylation of c-Jun N-terminal kinase-1 and p38 were
involved in gambogic acid induced cell cycle arrest and apoptosis
in human breast carcinoma MCF-7 cells. Life Sci. 83:103–109. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Wang S, Wang L, Chen M and Wang Y:
Gambogic acid sensitizes resistant breast cancer cells to
doxorubicin through inhibiting P-glycoprotein and suppressing
survivin expression. Chem Biol Interact. 235:76–84. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Favata MF, Horiuchi KY, Manos EJ, Daulerio
AJ, Stradley DA, Feeser WS, Van Dyk DE, Pitts WJ, Earl RA, Hobbs F,
et al: Identification of a novel inhibitor of mitogen-activated
protein kinase kinase. J Biol Chem. 273:18623–18632. 1998.
View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Raivich G, Bohatschek M, Da Costa C, Iwata
O, Galiano M, Hristova M, Nateri AS, Makwana M, Riera-Sans L,
Wolfer DP, et al: The AP-1 transcription factor c-Jun is required
for efficient axonal regeneration. Neuron. 43:57–67. 2004.
View Article : Google Scholar : PubMed/NCBI
|
