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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
November-2015 Volume 47 Issue 5

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

The JAK/STAT signaling cascade in gastric carcinoma (Review)

Puja Khanna, Pei Jou Chua, Boon Huat Bay, Gyeong Hun Baeg
Pages: 1617-1626
Published online on: 14 September 2015

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Review Open Access

Macrophage migration inhibitory factor involvement in breast cancer (Review)

Vincent Richard, Nadège Kindt, Sven Saussez
Pages: 1627-1633
Published online on: 24 September 2015

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Article Open Access

TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro

Judith Müller, Viktor Maurer, Kerstin Reimers, Peter M. Vogt, Vesna Bucan
Pages: 1634-1646
Published online on: 16 September 2015

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Article Open Access

Antitumorigenic effect of interferon-β by inhibition of undifferentiated glioblastoma cells

Shun Yamamuro, Emiko Sano, Yutaka Okamoto, Yushi Ochiai, Takashi Ohta, Akiyoshi Ogino, Atsushi Natsume, Toshihiko Wakabayashi, Takuya Ueda, Hiroyuki Hara, Tomohiro Nakayama, Atsuo Yoshino, Yoichi Katayama
Pages: 1647-1654
Published online on: 14 September 2015

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Article Open Access

Effectiveness of plasma treatment on pancreatic cancer cells

Norifumi Hattori, Suguru Yamada, Koji Torii, Shigeomi Takeda, Kae Nakamura, Hiromasa Tanaka, Hiroaki Kajiyama, Mitsuro Kanda, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Shuji Nomoto, Michitaka Fujiwara, Masaaki Mizuno, Masaru Hori, Yasuhiro Kodera
Pages: 1655-1662
Published online on: 07 September 2015

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Article Open Access

Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells

Chuangyu Wen, Lanlan Huang, Junxiong Chen, Mengmeng Lin, Wen Li, Biyan Lu, Zina Jeyapalan Rutnam, Aikichi Iwamoto, Zhongyang Wang, Xiangling Yang, Huanliang Liu
Pages: 1663-1671
Published online on: 15 September 2015

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Article Open Access

MicroRNA-132 inhibits cell growth and metastasis in osteosarcoma cell lines possibly by targeting Sox4 Retraction in /10.3892/ijo.2023.5537

Yulong Liu, Ye Li, Jingchen Liu, Yuntao Wu, Qingsan Zhu
Pages: 1672-1684
Published online on: 07 September 2015

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Article Open Access

Restoration of CCAAT enhancer binding protein α P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells

Limengmeng Wang, Haowen Xiao, Xing Zhang, Weichao Liao, Shan Fu, He Huang
Pages: 1685-1695
Published online on: 14 September 2015

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Article Open Access

The Eltrombopag antitumor effect on hepatocellular carcinoma

Tomohiro Kurokawa, Soichiro Murata, Yun-Wen Zheng, Kenichi Iwasaki, Keisuke Kohno, Kiyoshi Fukunaga, Nobuhiro Ohkohchi
Pages: 1696-1702
Published online on: 23 September 2015

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Article

OTX2 is a therapeutic target for retinoblastoma and may function as a common factor between C-MYC, CRX, and phosphorylated RB pathways

Jing Li, Chunhui Di, Jenny Jing, Qun Di, Jonathan Nakhla, David Cory Adamson
Pages: 1703-1710
Published online on: 23 September 2015

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Article

Therapeutic potential of thalidomide for gemcitabine-resistant bladder cancer

Yen Ta Huang, Chuan Chu Cheng, Ted H. Chiu, Pei Chun Lai
Pages: 1711-1724
Published online on: 11 September 2015

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Article

Fra-1 is upregulated in gastric cancer tissues and affects the PI3K/Akt and p53 signaling pathway in gastric cancer

Junyu He, Guangchao Zhu, Lu Gao, Pan Chen, Yuehua Long, Shan Liao, Hong Yi, Wei Yi, Zhen Pei, Minghua Wu, Xiaoling Li, Juanjuan Xiang, Shuping Peng, Jian Ma, Ming Zhou, Wei Xiong, Zhaoyang Zeng, Bo Xiang, Ke Tang, Li Cao, Guiyuan Li, Yanhong Zhou
Pages: 1725-1734
Published online on: 02 September 2015

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Article

Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy

Gabriel G. Vega, Luz Areli Franco-Cea, Sara Huerta-Yepez, Héctor Mayani, Sherie L. Morrison, Benjamin Bonavida, Mario I. Vega
Pages: 1735-1748
Published online on: 16 September 2015

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Article

Colon cancer chemopreventive effects of baicalein, an active enteric microbiome metabolite from baicalin

Chong-Zhi Wang, Chun-Feng Zhang, Lina Chen, Samantha Anderson, Fang Lu, Chun-Su Yuan
Pages: 1749-1758
Published online on: 18 September 2015

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Article

Elevation of miR-27b by HPV16 E7 inhibits PPARγ expression and promotes proliferation and invasion in cervical carcinoma cells

Shimeng Zhang, Fei Liu, Xinru Mao, Jinlan Huang, Junyao Yang, Xiaomao Yin, Lijuan Wu, Lei Zheng, Qian Wang
Pages: 1759-1766
Published online on: 14 September 2015

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Article

Toosendanin inhibits growth and induces apoptosis in colorectal cancer cells through suppression of AKT/GSK-3β/β-catenin pathway

Ge Wang, Cheng-Cheng Feng, Shao-Jun Chu, Rui Zhang, Yun-Min Lu, Jin-Shui Zhu, Jing Zhang
Pages: 1767-1774
Published online on: 11 September 2015

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Article

Livin modulates the apoptotic effects of vesicular stomatotitis virus in lung adenocarcinoma

Gui-Hong Liu, Wei-Lin Wang, Chun Wang, Chang-Lin Li, Xiao-Long Zhang, Qiu Li, Zhen-Yu Ding
Pages: 1775-1782
Published online on: 24 September 2015

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Article

Targeted inhibition of mitochondrial Hsp90 induces mitochondrial elongation in Hep3B hepatocellular carcinoma cells undergoing apoptosis by increasing the ROS level

Seung Hee Yoo, Hye Young Kim, Jee Hyun Rho, Seon-Yong Jeong, Jeanho Yun, Il Yun, Hwan Tae Park, Young Hyun Yoo
Pages: 1783-1792
Published online on: 07 September 2015

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Article

The anticancer mechanism of 2'-hydroxycinnamaldehyde in human head and neck cancer cells

Sang-Gun Ahn, Young-Hee Jin, Jung-Hoon Yoon, Soo-A Kim
Pages: 1793-1800
Published online on: 08 September 2015

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Article

miR-125a regulates angiogenesis of gastric cancer by targeting vascular endothelial growth factor A

Jun Dai, Jinyu Wang, Lili Yang, Ying Xiao, Qiurong Ruan
Pages: 1801-1810
Published online on: 17 September 2015

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Article

Adherens junctions associated protein 1 serves as a predictor of recurrence of squamous cell carcinoma of the esophagus

Haruyoshi Tanaka, Mitsuro Kanda, Masahiko Koike, Naoki Iwata, Dai Shimizu, Kazuhiro Ezaka, Satoshi Sueoka, Yuri Tanaka, Hideki Takami, Ryoji Hashimoto, Chie Tanaka, Suguru Yamada, Tsutomu Fujii, Goro Nakayama, Hiroyuki Sugimoto, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 1811-1818
Published online on: 16 September 2015

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Article

The inhibition of histone deacetylase 8 suppresses proliferation and inhibits apoptosis in gastric adenocarcinoma

Shiyuan Song, Ying Wang, Po Xu, Ruina Yang, Zhikun Ma, Shuo Liang, Guangping Zhang
Pages: 1819-1828
Published online on: 24 September 2015

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Article

LncRNA expression profiles and validation in keloid and normal skin tissue

Xuebing Liang, Lin Ma, Xiao Long, Xiaojun Wang
Pages: 1829-1838
Published online on: 22 September 2015

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Article

Protein kinase Cα-mediated cytotoxic activity of ineupatorolide B from Inula cappa DC. in HeLa cells

Mei Dong, Takaki Hiwasa, Bin Cong, Qing-Wen Shi, Si-Ming Wang, Kazuko Kita, Shigeru Sugaya, Nobuo Suzuki
Pages: 1839-1844
Published online on: 17 September 2015

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Article

Mitochondrial dysfunction induces EMT through the TGF-β/Smad/Snail signaling pathway in Hep3B hepatocellular carcinoma cells

Eui-Yeun Yi, Shi-Young Park, Seung-Youn Jung, Won-Jun Jang, Yung-Jin Kim
Pages: 1845-1853
Published online on: 10 September 2015

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Article

The antitumor mechanism of di-2-pyridylketone 2-pyridine carboxylic acid hydrazone and its copper complex in ROS generation and topoisomerase inhibition, and hydrazone involvement in oxygen-catalytic iron mobilization

Tengfei Huang, Cuiping Li, Xingzhi Sun, Zhenfu Zhu, Yun Fu, Youxun Liu, Yanbin Yuan, Shaoshan Li, Changzheng Li
Pages: 1854-1862
Published online on: 11 September 2015

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Article

SNAILs promote G1 phase in selected cancer cells

Ya-Lan Wu, Jian-Xin Xue, Lin Zhou, Lei Deng, Yan-Na Shang, Fang Liu, Xian-Ming Mo, You Lu
Pages: 1863-1873
Published online on: 07 September 2015

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Article

Paclitaxel suppresses the viability of breast tumor MCF7 cells through the regulation of EF1α and FOXO3a by AMPK signaling

Ji Hae Kim, Jung Ok Lee, Nami Kim, Hye Jeong Lee, Yong Woo Lee, Hyung Ip Kim, Su Jin Kim, Sun Hwa Park, Hyeon Soo Kim
Pages: 1874-1880
Published online on: 10 September 2015

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Article

Gene therapy for colorectal cancer by adenovirus-mediated siRNA targeting CD147 based on loss of the IGF2 imprinting system

Yuqin Pan, Bangshun He, Jie Chen, Huiling Sun, Qiwen Deng, Feng Wang, Houqun Ying, Xian Liu, Kang Lin, Hongxin Peng, Hongguang Xie, Shukui Wang
Pages: 1881-1889
Published online on: 23 September 2015

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Article

Autophagic flux promotes cisplatin resistance in human ovarian carcinoma cells through ATP-mediated lysosomal function

Liwei Ma, Ye Xu, Jing Su, Huimei Yu, Jinsong Kang, Hongyan Li, Xiaoning Li, Qi Xie, Chunyan Yu, Liankun Sun, Yang Li
Pages: 1890-1900
Published online on: 21 September 2015

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Article

Immunotherapy of tumors with human telomerase reverse transcriptase immortalized human umbilical vein endothelial cells

Xiyan Mu, Yaxiong Sang, Chunju Fang, Bin Shao, Lu Yang, Kui Yao, Xitong Zhao, Jinhai Gou, Yuquan Wei, Tao Yi, Yang Wu, Xia Zhao
Pages: 1901-1911
Published online on: 21 September 2015

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Article

Cantharidin and norcantharidin impair stemness of pancreatic cancer cells by repressing the β-catenin pathway and strengthen the cytotoxicity of gemcitabine and erlotinib

Wen-Jie Wang, Meng-Yao Wu, Meng Shen, Qiaoming Zhi, Ze-Yi Liu, Fei-Ran Gong, Min Tao, Wei Li
Pages: 1912-1922
Published online on: 11 September 2015

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Article

SCTR regulates cell cycle-related genes toward anti-proliferation in normal breast cells while having pro-proliferation activity in breast cancer cells

Seongeun Kang, Byungtak Kim, Han-Sung Kang, Gookjoo Jeong, Hansol Bae, Hyunkyung Lee, Seungyeon Lee, Sun Jung Kim
Pages: 1923-1931
Published online on: 14 September 2015

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Article

A quantitative proteomics study on olfactomedin 4 in the development of gastric cancer

Xiaoping Ran, Xiaoming Xu, Yixuan Yang, Sha She, Min Yang, Shiying Li, Hong Peng, Xiangchun Ding, Huaidong Hu, Peng Hu, Dazhi Zhang, Hong Ren, Ligang Wu, Weiqun Zeng
Pages: 1932-1944
Published online on: 16 September 2015

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Article

A comparative study on the effect of docetaxel-albumin nanoparticles and docetaxel-loaded PEG-albumin nanoparticles against non-small cell lung cancer

Guangming Jin, Mingji Jin, Xuezhe Yin, Zhehu Jin, Liqing Chen, Zhonggao Gao
Pages: 1945-1953
Published online on: 18 September 2015

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Article

Manumycin A from a new Streptomyces strain induces endoplasmic reticulum stress-mediated cell death through specificity protein 1 signaling in human oral squamous cell carcinoma

Jung Jae Cho, Jung-Il Chae, Ka Hwi Kim, Jin Hyoung Cho, Young-Joo Jeon, Ha Na Oh, Goo Yoon, Do Young Yoon, Young Sik Cho, Seung-Sik Cho, Jung-Hyun Shim
Pages: 1954-1962
Published online on: 08 September 2015

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Article

miR-506 regulates breast cancer cell metastasis by targeting IQGAP1

Guang Sun, Yanxi Liu, Keren Wang, Zheli Xu
Pages: 1963-1970
Published online on: 14 September 2015

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Article

IκBζ, an atypical member of the inhibitor of nuclear factor kappa B family, is induced by γ-irradiation in glioma cells, regulating cytokine secretion and associated with poor prognosis

Heiko Brennenstuhl, Angela Armento, Anne Kristin Braczysnki, Michel Mittelbronn, Ulrike Naumann
Pages: 1971-1980
Published online on: 14 September 2015

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Article

MicroRNA-203 induces apoptosis by upregulating Puma expression in colon and lung cancer cells

Naotake Funamizu, Curtis R. Lacy, Minori Kamada, Katsuhiko Yanaga, Yoshinobu Manome
Pages: 1981-1988
Published online on: 22 September 2015

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Article

Human rhabdomyosarcoma cells express functional erythropoietin receptor: Potential therapeutic implications

Agata Poniewierska-Baran, Malwina Suszynska, Wenyue Sun, Ahmed Abdelbaset-Ismail, Gabriela Schneider, Frederic G. Barr, Mariusz Z. Ratajczak
Pages: 1989-1997
Published online on: 24 September 2015

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Journal Cover
January-2026 Volume 68 Issue 1

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Article Open Access

c‑Myc‑regulated RPLP0 via the ROS‑mediated JAK2/STAT3 positive feedback loop facilitates hepatocellular carcinoma malignancy progression

Yanqiu Meng, Lebin Yuan, Gangrui Meng, Hongxiang Huang, Xianbin Huang, Xinping Xu, Xiaodong Peng
Article Number: 13
Published online on: 27 November 2025

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Review Open Access

Obesity, chronic breast inflammation and carcinogenesis: Molecular pathways and clinical implications (Review)

Fangying Li, Zhenhua Gao
Article Number: 12
Published online on: 27 November 2025

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Review Open Access

The tumor microenvironment in lung cancer: Heterogeneity, therapeutic resistance and emerging treatment strategies (Review)

Li Liu, Li Yang, Hongmin Li, Tianlu Shang, Lihan Liu
Article Number: 11
Published online on: 26 November 2025

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Article Open Access

Discovery of the late autophagy inhibitor FZU‑0045‑053 and its anti‑breast cancer and immunomodulatory effects

Jinlan Luo, Yi Yang, Lulu Cheng, Fangting Cheng, Huangwenlong Zhuang, Shanshan Chen, Panpan Qiao, Yinbin Liang, Li Chen, Yang Sun, Haijun Chen, Qinying Liu
Article Number: 10
Published online on: 26 November 2025

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Correction Open Access

[Corrigendum] RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling

Zi-Hao Qi, Hua-Xiang Xu, Shi-Rong Zhang, Jin-Zhi Xu, Shuo Li, He-Li Gao, Wei Jin, Wen-Quan Wang, Chun-Tao Wu, Quan-Xing Ni, Xian-Jun Yu, Liang Liu
Article Number: 9
Published online on: 24 November 2025

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Article Open Access

Ephrin‑B2 promotes gastric cancer growth by inhibiting apoptosis and regulating the cell cycle via the Wnt/β‑catenin signaling pathway

Ding Ding, Xiaoshan Wang, Ran Xuan, Rui Li, Yalu Zhang, Zhengguang Wang
Article Number: 8
Published online on: 18 November 2025

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Expression of Concern Open Access

[Expression of Concern] Gene therapy for human colorectal cancer cell lines with recombinant adenovirus 5 based on loss of the insulin‑like growth factor 2 imprinting

Huiling Sun, Yuqin Pan, Bangshun He, Qiwen Deng, Rui Li, Yeqiong Xu, Jie Chen, Tianyi Gao, Houqun Ying, Feng Wang, Xian Liu, Shukui Wang
Article Number: 7
Published online on: 18 November 2025

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Review Open Access

Ferroptosis in biliary tract cancer: Molecular mechanisms and therapeutic applications (Review)

Ruiqi Zou, Yushi Dai, Siqi Yang, Haijie Hu, Fuyu Li, Fei Liu
Article Number: 6
Published online on: 14 November 2025

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Expression of Concern Open Access

[Expression of Concern] Radiosensitization of esophageal carcinoma cells by knockdown of RNF2 expression

Xing-Xiao Yang, Ming Ma, Mei-Xiang Sang, Xue-Xiao Wang, Heng Song, Zhi-Kun Liu, Shu-Chai Zhu
Article Number: 5
Published online on: 10 November 2025

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Review Open Access

Targeting ferroptosis in Helicobacter pylori‑associated gastric cancer development: From molecular mechanisms to application prospects (Review)

Chen-Yi Wang, Meng-Hui Wang, Chuan Xie
Article Number: 4
Published online on: 05 November 2025

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Expression of Concern Open Access

[Expression of Concern] Leptin promotes breast cancer cell migration and invasion via IL‑18 expression and secretion

Kuangfa Li, Lan Wei, Yunxiu Huang, Yang Wu, Min Su, Xueli Pang, Nian Wang, Feihu Ji, Changli Zhong, Tingmei Chen
Article Number: 3
Published online on: 04 November 2025

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Review Open Access

Cancer immunotherapy strategies based on transition‑metal medical materials: Still a long way to go (Review)

Zhefei Du, Zhenyu Cao, Chao Fang, Daihan Xie, Lixin Xie, Chunxia Su, Yu Huo
Article Number: 2
Published online on: 04 November 2025

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Expression of Concern Open Access

[Expression of Concern] Regulation of NADPH oxidase (Nox2) by lipid rafts in breast carcinoma cells

Rama Rao Malla, Hari Raghu, Jasti S. Rao
Article Number: 1
Published online on: 23 October 2025

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Journal Cover
February-2026 Volume 68 Issue 2

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Journal Metrics

Impact Factor: 4.9

CiteScore: 8.9

CiteScore Rank: Q1: #66/415 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Retraction Open Access

[Retracted] Cdc42 expression in cervical cancer and its effects on cervical tumor invasion and migration

Hongnan Ye, Youyi Zhang, Li Geng, Zijian Li
Article Number: 20
Published online on: 05 December 2025

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Article Open Access

Regulation and reversal of paclitaxel resistance via the STAT1‑mediated apoptotic pathway in ovarian cancer

Fanchen Wang, Xiaolin Xu, Bin Guan, Xin Li, Jia Yuan, Wencai Guan, Junyu Chen, Jingyi Fang, Qi Lu, Guoxiong Xu
Article Number: 19
Published online on: 05 December 2025

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Review

Cancer stem cell heterogeneity‑inspired therapeutics for enhancing tumor treatment outcomes (Review)

Hanning Xu, Qunchao Si, Yongyao Song, Shengping Sun, Xianghong Wei, Hui Long, Xiaomei Wang
Article Number: 18
Published online on: 04 December 2025

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Review Open Access

Roles of interleukins in spasmolytic polypeptide‑expressing metaplasia (Review)

Jiale Ma, Tiancheng Zhan, Xinyuan Zhang, Wang Gao, Shuangmei Zhao, Huizhen Li
Article Number: 17
Published online on: 03 December 2025

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Expression of Concern Open Access

[Expression of Concern] MUC1 is a downstream target of STAT3 and regulates lung cancer cell survival and invasion

Jingchun Gao, Matthew J. Mcconnell, Bin Yu, Jiannong Li, Justin M. Balko, Esther P. Black, Joseph O. Johnson, Mark C. Lloyd, Soner Altiok, Eric B. Haura
Article Number: 16
Published online on: 03 December 2025

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Review Open Access

Emerging biomarkers in prostate cancer diagnosis and treatment: Insights into genetic, RNA and metabolic markers (Review)

Yuanshe Huang, Jingxin Mao, Xiaobing Li
Article Number: 15
Published online on: 03 December 2025

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Retraction Open Access

[Retracted] GDC‑0152 attenuates the malignant progression of osteosarcoma promoted by ANGPTL2 via PI3K/AKT but not p38MAPK signaling pathway

Lin Yang, Taipengfei Shu, Yingjian Liang, Wenguang Gu, Chunlei Wang, Xuanhe Song, Changdong Fan, Wenbo Wang
Article Number: 14
Published online on: 01 December 2025

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