|
1
|
Torre LA, Bray F, Siegel RL, Ferlay J,
Lortet-Tieulent J and Jemal A: Global cancer statistics, 2012. CA
Cancer J Clin. 65:87–108. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Siegel RL, Miller KD and Jemal A: Cancer
statistics, 2015. CA Cancer J Clin. 65:5–29. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Gray R, Barnwell J, McConkey C, Hills RK,
Williams NS and Kerr DJ; Quasar Collaborative Group. Adjuvant
chemotherapy versus observation in patients with colorectal cancer:
A randomised study. Lancet. 370:2020–2029. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ernst E: The role of complementary and
alternative medicine in cancer. Lancet Oncol. 1:176–180. 2000.
View Article : Google Scholar
|
|
5
|
Sampson W: Natural products and cancer. A
Textbook of Complementary and Alternative Medicine. 2nd edition.
Yuan CS, Bieber EJ and Bauer BA: Parthenon/CRC; London: pp.
645–654. 2006
|
|
6
|
Cragg GM, Grothaus PG and Newman DJ:
Impact of natural products on developing new anti-cancer agents.
Chem Rev. 109:3012–3043. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
7
|
Butler MS, Robertson AA and Cooper MA:
Natural product and natural product derived drugs in clinical
trials. Nat Prod Rep. 31:1612–1661. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Wang CY, Bai XY and Wang CH: Traditional
Chinese medicine: A treasured natural resource of anticancer drug
research and development. Am J Chin Med. 42:543–559. 2014.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Chen R, Zhang J, Hu Y, Wang S, Chen M and
Wang Y: Potential antineoplastic effects of Aloe-emodin: A
comprehensive review. Am J Chin Med. 42:275–288. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kim EH, Shim B, Kang S, Jeong G, Lee JS,
Yu YB and Chun M: Anti-inflammatory effects of Scutellaria
baicalensis extract via suppression of immune modulators and MAP
kinase signaling molecules. J Ethnopharmacol. 126:320–331. 2009.
View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Arweiler NB, Pergola G, Kuenz J, Hellwig
E, Sculean A and Auschill TM: Clinical and antibacterial effect of
an anti-inflammatory toothpaste formulation with Scutellaria
baicalensis extract on experimental gingivitis. Clin Oral Investig.
15:909–913. 2011. View Article : Google Scholar
|
|
12
|
Li-Weber M: New therapeutic aspects of
flavones: The anti-cancer properties of Scutellaria and its main
active constituents Wogonin, Baicalein and Baicalin. Cancer Treat
Rev. 35:57–68. 2009. View Article : Google Scholar
|
|
13
|
Chen HM, Liou SF, Hsu JH, Chen TJ, Cheng
TL, Chiu CC and Yeh JL: Baicalein inhibits HMGB1 release and
MMP-2/-9 expression in lipopolysaccharide-induced cardiac
hypertrophy. Am J Chin Med. 42:785–797. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Li C, Zhou L, Lin G and Zuo Z: Contents of
major bioactive flavones in proprietary traditional Chinese
medicine products and reference herb of radix Scutellariae. J Pharm
Biomed Anal. 50:298–306. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yu C, Qu F, Mao Y, Li D, Zhen Z, Nass R,
Calway T, Wang Y, Yuan CS and Wang CZ: Different extraction
pretreatments significantly change the flavonoid contents of
Scutellaria baicalensis. Pharm Biol. 51:1228–1235. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Shi R, Zhou H, Liu Z, Ma Y, Wang T, Liu Y
and Wang C: Influence of coptis Chinensis on pharmacokinetics of
flavonoids after oral administration of radix Scutellariae in rats.
Biopharm Drug Dispos. 30:398–410. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hasegawa H: Proof of the mysterious
efficacy of ginseng: Basic and clinical trials: metabolic
activation of ginsenoside: Deglycosylation by intestinal bacteria
and esterification with fatty acid. J Pharmacol Sci. 95:153–157.
2004. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Liu H, Yang J, Du F, Gao X, Ma X, Huang Y,
Xu F, Niu W, Wang F, Mao Y, et al: Absorption and disposition of
ginsenosides after oral administration of Panax notoginseng extract
to rats. Drug Metab Dispos. 37:2290–2298. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Tawab MA, Bahr U, Karas M, Wurglics M and
Schubert-Zsilavecz M: Degradation of ginsenosides in humans after
oral administration. Drug Metab Dispos. 31:1065–1071. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yu C, Zhang Z, Zhang H, Zhen Z, Calway T,
Wang Y, Yuan CS and Wang CZ: Pretreatment of baicalin and
wogonoside with glycoside hydrolase: A promising approach to
enhance anti-cancer potential. Oncol Rep. 30:2411–2418.
2013.PubMed/NCBI
|
|
21
|
Wang CZ, Du GJ, Zhang Z, Wen XD, Calway T,
Zhen Z, Musch MW, Bissonnette M, Chang EB and Yuan CS: Ginsenoside
compound K, not Rb1, possesses potential chemopreventive activities
in human colorectal cancer. Int J Oncol. 40:1970–1976.
2012.PubMed/NCBI
|
|
22
|
Gao JL, Lv GY, He BC, Zhang BQ, Zhang H,
Wang N, Wang CZ, Du W, Yuan CS and He TC: Ginseng saponin
metabolite 20(S)-protopanaxadiol inhibits tumor growth by targeting
multiple cancer signaling pathways. Oncol Rep. 30:292–298.
2013.PubMed/NCBI
|
|
23
|
Gong WY, Wu JF, Liu BJ, Zhang HY, Cao YX,
Sun J, Lv YB, Wu X and Dong JC: Flavonoid components in Scutellaria
baicalensis inhibit nicotine-induced proliferation, metastasis and
lung cancer-associated inflammation in vitro. Int J Oncol.
44:1561–1570. 2014.PubMed/NCBI
|
|
24
|
Lin C, Tsai SC, Tseng MT, Peng SF, Kuo SC,
Lin MW, Hsu YM, Lee MR, Amagaya S, Huang WW, et al: AKT
serine/threonine protein kinase modulates baicalin-triggered
autophagy in human bladder cancer T24 cells. Int J Oncol.
42:993–1000. 2013.PubMed/NCBI
|
|
25
|
Wan JY, Liu P, Wang HY, Qi LW, Wang CZ, Li
P and Yuan CS: Biotransformation and metabolic profile of American
ginseng saponins with human intestinal microflora by liquid
chromatography quadrupole time-of-flight mass spectrometry. J
Chromatogr A. 1286:83–92. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Chen WC, Kuo TH, Tzeng YS and Tsai YC:
Baicalin induces apoptosis in SW620 human colorectal carcinoma
cells in vitro and suppresses tumor growth in vivo. Molecules.
17:3844–3857. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kim SJ, Kim HJ, Kim HR, Lee SH, Cho SD,
Choi CS, Nam JS and Jung JY: Antitumor actions of baicalein and
wogonin in HT-29 human colorectal cancer cells. Mol Med Rep.
6:1443–1449. 2012.PubMed/NCBI
|
|
28
|
Xu Z, Wu G, Wei X, Chen X, Wang Y and Chen
L: Celastrol induced DNA damage, cell cycle arrest, and apoptosis
in human rheumatoid fibroblast-like synovial cells. Am J Chin Med.
41:615–628. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Sai K, Li WY, Chen YS, Wang J, Guan S,
Yang QY, Guo CC, Mou YG, Li WP and Chen ZP: Triptolide
synergistically enhances temozolomide-induced apoptosis and
potentiates inhibition of NF-κB signaling in glioma initiating
cells. Am J Chin Med. 42:485–503. 2014. View Article : Google Scholar
|
|
30
|
Jain AN: Morphological similarity: A 3D
molecular similarity method correlated with protein-ligand
recognition. J Comput Aided Mol Des. 14:199–213. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Giganti D, Guillemain H, Spadoni JL,
Nilges M, Zagury JF and Montes M: Comparative evaluation of 3D
virtual ligand screening methods: Impact of the molecular alignment
on enrichment. J Chem Inf Model. 50:992–1004. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Kim R, Tanabe K, Uchida Y, Emi M, Inoue H
and Toge T: Current status of the molecular mechanisms of
anticancer drug-induced apoptosis. The contribution of
molecular-level analysis to cancer chemotherapy. Cancer Chemother
Pharmacol. 50:343–352. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Hanna RK and Soper JT: The role of surgery
and radiation therapy in the management of gestational
trophoblastic disease. Oncologist. 15:593–600. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Russo R, Corasaniti MT, Bagetta G and
Morrone LA: Exploitation of cytotoxicity of some essential oils for
translation in cancer therapy. Evid Based Complement Alternat Med.
2015:3978212015.PubMed/NCBI
|
|
35
|
Wang CZ, Li XL, Wang QF, Mehendale SR,
Fishbein AB, Han AH, Sun S and Yuan CS: The mitochondrial pathway
is involved in American ginseng-induced apoptosis of SW-480 colon
cancer cells. Oncol Rep. 21:577–584. 2009.PubMed/NCBI
|
|
36
|
Wang CZ, Li XL, Wang QF, Mehendale SR and
Yuan CS: Selective fraction of Scutellaria baicalensis and its
chemopreventive effects on MCF-7 human breast cancer cells.
Phytomedicine. 17:63–68. 2010. View Article : Google Scholar
|
|
37
|
Zhang J, Park HS, Kim JA, Hong GE,
Nagappan A, Park KI and Kim GS: Flavonoids identified from Korean
Scutellaria baicalensis induce apoptosis by ROS generation and
caspase activation on human fibrosarcoma cells. Am J Chin Med.
42:465–483. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Wang CZ, Calway TD, Wen XD, Smith J, Yu C,
Wang Y, Mehendale SR and Yuan CS: Hydrophobic flavonoids from
Scutellaria baicalensis induce colorectal cancer cell apoptosis
through a mitochondrial-mediated pathway. Int J Oncol.
42:1018–1026. 2013.PubMed/NCBI
|
|
39
|
Ismail B, Ghezali L, Gueye R, Limami Y,
Pouget C, Leger DY, Martin F, Beneytout JL, Duroux JL, Diab-Assaf
M, et al: Novel methylsulfonyl chalcones as potential
antiproliferative drugs for human prostate cancer: Involvement of
the intrinsic pathway of apoptosis. Int J Oncol. 43:1160–1168.
2013.PubMed/NCBI
|
