|
1
|
Artavanis-Tsakonas S, Rand MD and Lake RJ:
Notch signaling: Cell fate control and signal integration in
development. Science. 284:770–776. 1999. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Davis RL and Turner DL: Vertebrate hairy
and Enhancer of split related proteins: Transcriptional repressors
regulating cellular differentiation and embryonic patterning.
Oncogene. 20:8342–8357. 2001. View Article : Google Scholar
|
|
3
|
Gao J, Liu J, Fan D, Xu H, Xiong Y, Wang
Y, Xu W, Wang Y, Cheng Y and Zheng G: Up-regulated expression of
Notch1 and Jagged1 in human colon adenocarcinoma. Pathol Biol
(Paris). 59:298–302. 2011. View Article : Google Scholar
|
|
4
|
Mazur PK, Riener MO, Jochum W, Kristiansen
G, Weber A, Schmid RM and Siveke JT: Expression and
clinicopathological significance of notch signaling and cell-fate
genes in biliary tract cancer. Am J Gastroenterol. 107:126–135.
2012. View Article : Google Scholar
|
|
5
|
Zhou M, Jin WY, Fan ZW and Han RC:
Analysis of the expression of the Notch3 receptor protein in adult
lung cancer. Oncol Lett. 5:499–504. 2013.PubMed/NCBI
|
|
6
|
Zhu H, Zhou X, Redfield S, Lewin J and
Miele L: Elevated Jagged-1 and Notch-1 expression in high grade and
metastatic prostate cancers. Am J Transl Res. 5:368–378.
2013.PubMed/NCBI
|
|
7
|
Jin HY, Zhang HY, Wang X, Xu J and Ding Y:
Expression and clinical significance of Notch signaling genes in
colorectal cancer. Tumour Biol. 33:817–824. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Ozawa T, Kazama S, Akiyoshi T, Murono K,
Yoneyama S, Tanaka T, Tanaka J, Kiyomatsu T, Kawai K, Nozawa H, et
al: Nuclear Notch3 expression is associated with tumor recurrence
in patients with stage II and III colorectal cancer. Ann Surg
Oncol. 21:2650–2658. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Ogawa R, Ishiguro H, Kimura M, Funahashi
H, Wakasugi T, Ando T, Shiozaki M and Takeyama H: NOTCH1 expression
predicts patient prognosis in esophageal squamous cell cancer. Eur
Surg Res. 51:101–107. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Tiollais P, Pourcel C and Dejean A: The
hepatitis B virus. Nature. 317:489–495. 1985. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Maguire HF, Hoeffler JP and Siddiqui A:
HBV X protein alters the DNA binding specificity of CREB and ATF-2
by protein-protein interactions. Science. 252:842–844. 1991.
View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Kekulé AS, Lauer U, Weiss L, Luber B and
Hofschneider PH: Hepatitis B virus transactivator HBx uses a tumour
promoter signalling pathway. Nature. 361:742–745. 1993. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Kim CM, Koike K, Saito I, Miyamura T and
Jay G: HBx gene of hepatitis B virus induces liver cancer in
transgenic mice. Nature. 351:317–320. 1991. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Shirakata Y, Kawada M, Fujiki Y, Sano H,
Oda M, Yaginuma K, Kobayashi M and Koike K: The X gene of hepatitis
B virus induced growth stimulation and tumorigenic transformation
of mouse NIH3T3 cells. Jpn J Cancer Res. 80:617–621. 1989.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Wang F, Zhou H, Yang Y, Xia X, Sun Q, Luo
J and Cheng B: Hepatitis B virus X protein promotes the growth of
hepatocellular carcinoma by modulation of the Notch signaling
pathway. Oncol Rep. 27:1170–1176. 2012.PubMed/NCBI
|
|
16
|
Wang F, Xia X, Wang J, Sun Q, Luo J and
Cheng B: Notch1 signaling contributes to the oncogenic effect of
HBx on human hepatic cells. Biotechnol Lett. 35:29–37. 2013.
View Article : Google Scholar
|
|
17
|
Sun Q, Wang R, Wang Y, Luo J, Wang P and
Cheng B: Notch1 is a potential therapeutic target for the treatment
of human hepatitis B virus X protein-associated HCC. Oncol Rep.
31:933–939. 2014.
|
|
18
|
Luo J, Zhou H, Wang F, Xia X, Sun Q, Wang
R and Cheng B: The hepatitis B virus X protein downregulates NF-κB
signaling pathways through decreasing the Notch signaling pathway
in HBx-transformed L02 cells. Int J Oncol. 42:1636–1643.
2013.PubMed/NCBI
|
|
19
|
Xu J, Yun X, Jiang J, Wei Y, Wu Y, Zhang
W, Liu Y, Wang W, Wen Y and Gu J: Hepatitis B virus X protein
blunts senescence-like growth arrest of human hepatocellular
carcinoma by reducing Notch1 cleavage. Hepatology. 52:142–154.
2010. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Gao J, Chen C, Hong L, Wang J, Du Y, Song
J, Shao X, Zhang J, Han H, Liu J, et al: Expression of Jagged1 and
its association with hepatitis B virus X protein in hepatocellular
carcinoma. Biochem Biophys Res Commun. 356:341–347. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kato H, Taniguchi Y, Kurooka H, Minoguchi
S, Sakai T, Nomura-Okazaki S, Tamura K and Honjo T: Involvement of
RBP-J in biological functions of mouse Notch1 and its derivatives.
Development. 124:4133–4141. 1997.PubMed/NCBI
|
|
22
|
Gao J, Song Z, Chen Y, Xia L, Wang J, Fan
R, Du R, Zhang F, Hong L, Song J, et al: Deregulated expression of
Notch receptors in human hepatocellular carcinoma. Dig Liver Dis.
40:114–121. 2008. View Article : Google Scholar
|
|
23
|
Struhl G and Adachi A: Nuclear access and
action of notch in vivo. Cell. 93:649–660. 1998. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Das I, Craig C, Funahashi Y, Jung KM, Kim
TW, Byers R, Weng AP, Kutok JL, Aster JC and Kitajewski J: Notch
oncoproteins depend on gamma-secretase/presenilin activity for
processing and function. J Biol Chem. 279:30771–30780. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Benn J and Schneider RJ: Hepatitis B virus
HBx protein activates Ras-GTP complex formation and establishes a
Ras, Raf, MAP kinase signaling cascade. Proc Natl Acad Sci USA.
91:10350–10354. 1994. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Shih WL, Kuo ML, Chuang SE, Cheng AL and
Doong SL: Hepatitis B virus X protein activates a survival
signaling by linking SRC to phosphatidylinositol 3-kinase. J Biol
Chem. 278:31807–31813. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Tarn C, Zou L, Hullinger RL and Andrisani
OM: Hepatitis B virus X protein activates the p38 mitogen-activated
protein kinase pathway in dedifferentiated hepatocytes. J Virol.
76:9763–9772. 2002. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Zeng Q, Li S, Chepeha DB, Giordano TJ, Li
J, Zhang H, Polverini PJ, Nor J, Kitajewski J and Wang CY:
Crosstalk between tumor and endothelial cells promotes tumor
angiogenesis by MAPK activation of Notch signaling. Cancer Cell.
8:13–23. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Weijzen S, Rizzo P, Braid M, Vaishnav R,
Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC,
et al: Activation of Notch-1 signaling maintains the neoplastic
phenotype in human Ras-transformed cells. Nat Med. 8:979–986. 2002.
View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Gao J, Dong Y, Zhang B, Xiong Y, Xu W,
Cheng Y, Dai M, Yu Z, Xu H and Zheng G: Notch1 activation
contributes to tumor cell growth and proliferation in human
hepatocellular carcinoma HepG2 and SMMC7721 cells. Int J Oncol.
41:1773–1781. 2012.PubMed/NCBI
|
|
31
|
Zhou L, Wang D, Li Q, Sun W, Zhang Y and
Dou K: The downregulation of Notch1 inhibits the invasion and
migration of HCC cells by inactivating the
cyclooxygenase-2/Snail/E-cadherin pathway in vitro. Dig Dis Sci.
58:1016–1025. 2013. View Article : Google Scholar
|
|
32
|
Hu Y, Li H, Qiu K, Li D, Zhou J, Hu Y and
Zhang F: Downregulation of Notch1 inhibits the invasion of human
HCC HepG2 and MHCC97H cells through the regulation of PTEN and FAK.
Int J Mol Med. 34:1081–1086. 2014.PubMed/NCBI
|
|
33
|
Zhou L, Zhang N, Song W, You N, Li Q, Sun
W, Zhang Y, Wang D and Dou K: The significance of Notch1 compared
with Notch3 in high metastasis and poor overall survival in HCC.
PLoS One. 8:e573822013. View Article : Google Scholar
|
|
34
|
Ahn S, Hyeon J and Park CK: Notch1 and
Notch4 are markers for poor prognosis of HCC. Hepatobiliary
Pancreat Dis Int. 12:286–294. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Oberg C, Li J, Pauley A, Wolf E, Gurney M
and Lendahl U: The Notch intracellular domain is ubiquitinated and
negatively regulated by the mammalian Sel-10 homolog. J Biol Chem.
276:35847–35853. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Kim MY, Jung J, Mo JS, Ann EJ, Ahn JS,
Yoon JH and Park HS: The intracellular domain of Jagged-1 interacts
with Notch1 intracellular domain and promotes its degradation
through Fbw7 E3 ligase. Exp Cell Res. 317:2438–2446. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
37
|
Choi YH, Kim HI, Seong JK, Yu DY, Cho H,
Lee MO, Lee JM, Ahn YH, Kim SJ and Park JH: Hepatitis B virus X
protein modulates peroxisome proliferator-activated receptor gamma
through protein-protein interaction. FEBS Lett. 557:73–80. 2004.
View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Kalra N and Kumar V: The X protein of
hepatitis B virus binds to the F box protein Skp2 and inhibits the
ubiquitination and proteasomal degradation of c-Myc. FEBS Lett.
580:431–436. 2006. View Article : Google Scholar
|
|
39
|
Zimber-Strobl U and Strobl LJ: EBNA2 and
Notch signalling in Epstein-Barr virus mediated immortalization of
B lymphocytes. Semin Cancer Biol. 11:423–434. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
40
|
Weijzen S, Zlobin A, Braid M, Miele L and
Kast WM: HPV16 E6 and E7 oncoproteins regulate Notch-1 expression
and cooperate to induce transformation. J Cell Physiol.
194:356–362. 2003. View Article : Google Scholar : PubMed/NCBI
|
