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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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International Journal of Oncology

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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
January-2016 Volume 48 Issue 1

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

IL-8, a novel messenger to cross-link inflammation and tumor EMT via autocrine and paracrine pathways (Review)

Xinxin Long, Yingnan Ye, Lijie Zhang, Pengpeng Liu, Wenwen Yu, Feng Wei, Xiubao Ren, Jinpu Yu
Pages: 5-12
Published online on: 06 November 2015

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Review Open Access

Pemetrexed clinical studies in performance status 2 patients with non-small cell lung cancer (Review)

Ralph Zinner, Carla Visseren-Grul, David R. Spigel, Coleman Obasaju
Pages: 13-27
Published online on: 29 October 2015

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Article Open Access

Involvement of cyclic-nucleotide response element-binding family members in the radiation response of Ramos B lymphoma cells

Chiara Di Nisio, Silvia Sancilio, Viviana Di Giacomo, Monica Rapino, Laura Sancillo, Domenico Genovesi, Alessandro Di Siena, Rosa Alba Rana, Amelia Cataldi, Roberta Di Pietro
Pages: 28-36
Published online on: 09 November 2015

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Article Open Access

Apoptosis and antitumor effects induced by the combination of an mTOR inhibitor and an autophagy inhibitor in human osteosarcoma MG63 cells

Ryosuke Horie, Osamu Nakamura, Yoshiki Yamagami, Masaki Mori, Hideki Nishimura, Natsuko Fukuoka, Tetsuji Yamamoto
Pages: 37-44
Published online on: 03 November 2015

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Article Open Access

Macrolides sensitize EGFR-TKI-induced non-apoptotic cell death via blocking autophagy flux in pancreatic cancer cell lines

Shuntaro Mukai, Shota Moriya, Masaki Hiramoto, Hiromi Kazama, Hiroko Kokuba, Xiao-Fang Che, Tomohisa Yokoyama, Satoshi Sakamoto, Akihiro Sugawara, Toshiaki Sunazuka, Satoshi Ōmura, Hiroshi Handa, Takao Itoi, Keisuke Miyazawa
Pages: 45-54
Published online on: 09 November 2015

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Article Open Access

Decreased expression of RASSF1A tumor suppressor gene is associated with worse prognosis in clear cell renal cell carcinoma

Jakub Klacz, Piotr M. Wierzbicki, Agata Wronska, Agnieszka Rybarczyk, Marcin Stanislawowski, Tomasz Slebioda, Agata Olejniczak, Marcin Matuszewski, Zbigniew Kmiec
Pages: 55-66
Published online on: 18 November 2015

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Article Open Access

Glucose starvation induces mutation and lineage-dependent adaptive responses in a large collection of cancer cell lines

Ningning He, Nayoung Kim, Euna Jeong, Yiling Lu, Gordon B. Mills, Sukjoon Yoon
Pages: 67-72
Published online on: 11 November 2015

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Article Open Access

Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells

Fatima H. Mohammed, Maitham A. Khajah, Ming Yang, William J. Brackenbury, Yunus A. Luqmani
Pages: 73-83
Published online on: 09 November 2015

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Article Open Access

Epigenetic induction of epithelial to mesenchymal transition by LCN2 mediates metastasis and tumorigenesis, which is abrogated by NF-κB inhibitor BRM270 in a xenograft model of lung adenocarcinoma

Raj Kumar Mongre, Simrinder Singh Sodhi, Neelesh Sharma, Mrinmoy Ghosh, Jeong Hyun Kim, Nameun Kim, Yang Ho Park, Young Gyu Shin, Sung Jin Kim, Zhang Jiao Jiao, Do Luong Huynh, Dong Kee Jeong
Pages: 84-98
Published online on: 13 November 2015

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Article Open Access

CD44v3+/CD24- cells possess cancer stem cell-like properties in human oral squamous cell carcinoma

Keita Todoroki, Sachiko Ogasawara, Jun Akiba, Masamichi Nakayama, Yoshiki Naito, Naoko Seki, Jingo Kusukawa, Hirohisa Yano
Pages: 99-109
Published online on: 20 November 2015

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Article

FH535 suppresses the proliferation and motility of hepatocellular carcinoma cells

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 110-114
Published online on: 29 October 2015

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Article

Characteristics of carbonic anhydrase 9 expressing cells in human intestinal crypt base

Hidekazu Takahashi, Yozo Suzuki, Junichi Nishimura, Naotsugu Haraguchi, Masahisa Ohtsuka, Susumu Miyazaki, Mamoru Uemura, Taishi Hata, Ichiro Takemasa, Tsunekazu Mizushima, Hirofumi Yamamoto, Yuichiro Doki, Masaki Mori
Pages: 115-122
Published online on: 20 November 2015

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Article

Suppression of hepatocellular carcinoma cell proliferation by short hairpin RNA of frizzled 2 with Sonazoid-enhanced irradiation

Minoru Tomizawa, Fuminobu Shinozaki, Yasufumi Motoyoshi, Takao Sugiyama, Shigenori Yamamoto, Naoki Ishige
Pages: 123-129
Published online on: 20 November 2015

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Article

Transcriptome sequencing of human breast cancer reveals aberrant intronic transcription in amplicons and dysregulation of alternative splicing with major therapeutic implications

Shiva Seyed Forootan, Joe M. Butler, Derek Gardener, Alison E. Baird, Andrew Dodson, Alistair Darby, John Kenny, Neil Hall, Andrew R. Cossins, Christopher S. Foster, Christine M. Gosden
Pages: 130-144
Published online on: 30 October 2015

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Article

A crucial epithelial to mesenchymal transition regulator, Sox4/Ezh2 axis is closely related to the clinical outcome in pancreatic cancer patients

Shinichiro Hasegawa, Hiroaki Nagano, Masamitsu Konno, Hidetoshi Eguchi, Akira Tomokuni, Yoshito Tomimaru, Tadafumi Asaoka, Hiroshi Wada, Naoki Hama, Koichi Kawamoto, Shigeru Marubashi, Naohiro Nishida, Jun Koseki, Masaki Mori, Yuichiro Doki, Hideshi Ishii
Pages: 145-152
Published online on: 20 November 2015

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Article

Epigenetic regulation of IQGAP2 promotes ovarian cancer progression via activating Wnt/β-catenin signaling

Zhuo Deng, Lijie Wang, Huilian Hou, Jiancheng Zhou, Xu Li
Pages: 153-160
Published online on: 04 November 2015

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Article

miR-21: A gene of dual regulation in breast cancer

Chunfu Zhang, Kui Liu, Tao Li, Jie Fang, Yanling Ding, Lingxian Sun, Tao Tu, Xinyi Jiang, Shanmei Du, Jiabo Hu, Wei Zhu, Huabiao Chen, Xiaochun Sun
Pages: 161-172
Published online on: 05 November 2015

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Article

Detection of neuroendocrine tumors using promoter-specific secreted Gaussia luciferase

Alan Wei-Shun Tseng, Victoria Akerstrom, Chiachen Chen, Mary B. Breslin, Michael S. Lan
Pages: 173-180
Published online on: 30 October 2015

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Article

miR-382 inhibits migration and invasion by targeting ROR1 through regulating EMT in ovarian cancer Corrigendum in /10.3892/ijo.2024.5698

Hong Tan, Qingnan He, Guanhui Gong, Yixuan Wang, Juanni Li, Junpu Wang, Ding Zhu, Xiaoying Wu
Pages: 181-190
Published online on: 09 November 2015

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Article

The impact of CDK9 on radiosensitivity, DNA damage repair and cell cycling of HNSCC cancer cells

Katja Storch, Nils Cordes
Pages: 191-198
Published online on: 13 November 2015

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Article

TIPE2 functions as a metastasis suppressor via negatively regulating β-catenin through activating GSK3β in gastric cancer

Jie Wu, Haitao Zhang, Chun Xu, Hong Xu, Xiumin Zhou, Yufeng Xie, Min Tao
Pages: 199-206
Published online on: 30 October 2015

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Article

IL-8 suppresses E-cadherin expression in nasopharyngeal carcinoma cells by enhancing E-cadherin promoter DNA methylation

Rui-Li Zhang, Li-Xia Peng, Jun-Ping Yang, Li-Sheng Zheng, Ping Xie, Meng-Yao Wang, Bi-Jun Huang, Hua-Rong Zhao, Yong-Xing Bao, Chao-Nan Qian
Pages: 207-214
Published online on: 02 November 2015

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Article

Interleukin-6 stimulates aerobic glycolysis by regulating PFKFB3 at early stage of colorectal cancer

Jun Han, Qingyang Meng, Qiulei Xi, Yongxian Zhang, Qiulin Zhuang, Yusong Han, Yi Jiang, Qiurong Ding, Guohao Wu
Pages: 215-224
Published online on: 02 November 2015

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Article

NF-κB signaling plays irreplaceable roles in cisplatin-induced bladder cancer chemoresistance and tumor progression

Yi Sun, Zhenfeng Guan, Liang Liang, Yongyi Cheng, Jiancheng Zhou, Jing Li, Yonggang Xu
Pages: 225-234
Published online on: 20 November 2015

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Article

Combination of Hedgehog inhibitors and standard anticancer agents synergistically prevent osteosarcoma growth

Yoshinobu Saitoh, Takao Setoguchi, Masahito Nagata, Arisa Tsuru, Shunsuke Nakamura, Satoshi Nagano, Yasuhiro Ishidou, Hiroko Nagao-Kitamoto, Masahiro Yokouchi, Shingo Maeda, Akihide Tanimoto, Tatsuhiko Furukawa, Setsuro Komiya
Pages: 235-242
Published online on: 06 November 2015

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Article

Downregulation of transient receptor potential cation channel, subfamily C, member 1 contributes to drug resistance and high histological grade in ovarian cancer

Xia Liu, Jing Zou, Jie Su, Yi Lu, Jian Zhang, Li Li, Fuqiang Yin
Pages: 243-252
Published online on: 19 November 2015

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Article

PF-04691502, a dual PI3K/mTOR inhibitor has potent pre-clinical activity by inducing apoptosis and G1 cell cycle arrest in aggressive B-cell non-Hodgkin lymphomas

Deyu Chen, Chaoming Mao, Yuepeng Zhou, Yuting Su, Shenzha Liu, Wen-Qing Qi
Pages: 253-260
Published online on: 05 November 2015

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Article

Ethanol extract of Kalopanax septemlobus leaf induces caspase-dependent apoptosis associated with activation of AMPK in human hepatocellular carcinoma cells

Cheol Park, Ji-Suk Jeong, Jin-Woo Jeong, Yong-Joo Kim, Yeon-Kwon Jung, Geun-Bae Go, Sung Ok Kim, Gi-Young Kim, Su-Hyun Hong, Young Hyun Yoo, Yung Hyun Choi
Pages: 261-270
Published online on: 05 November 2015

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Article

CA IX is upregulated in CoCl2-induced hypoxia and associated with cell invasive potential and a poor prognosis of breast cancer

Cheng-Yu Chu, Yi-Ting Jin, Wei Zhang, Juan Yu, Hai-Ping Yang, Hong-Ying Wang, Zi-Jing Zhang, Xiu-Ping Liu, Qiang Zou
Pages: 271-280
Published online on: 19 November 2015

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Article

Theaflavin-3, 3'-digallate decreases human ovarian carcinoma OVCAR-3 cell-induced angiogenesis via Akt and Notch-1 pathways, not via MAPK pathways

Ying Gao, Gary O. Rankin, Youying Tu, Yi Charlie Chen
Pages: 281-292
Published online on: 20 November 2015

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Article

Diallyl trisulfide induces apoptosis by suppressing NF-κB signaling through destabilization of TRAF6 in primary effusion lymphoma

Zenpei Shigemi, Yoshiki Furukawa, Kohei Hosokawa, Setsuya Minami, Jumpei Matsuhiro, Shiori Nakata, Tadashi Watanabe, Hiroki Kagawa, Koji Nakagawa, Hiroshi Takeda, Masahiro Fujimuro
Pages: 293-304
Published online on: 17 November 2015

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Article

Exosomes derived from SW480 colorectal cancer cells promote cell migration in HepG2 hepatocellular cancer cells via the mitogen-activated protein kinase pathway

Mitsuru Chiba, Narumi Watanabe, Miki Watanabe, Maki Sakamoto, Akika Sato, Mizuki Fujisaki, Shiori Kubota, Satoru Monzen, Atsushi Maruyama, Naoki Nanashima, Ikuo Kashiwakura, Toshiya Nakamura
Pages: 305-312
Published online on: 19 November 2015

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Article

3D matrix-based cell cultures: Automated analysis of tumor cell survival and proliferation

Iris Eke, Stephanie Hehlgans, Veit Sandfort, Nils Cordes
Pages: 313-321
Published online on: 04 November 2015

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Article

The antipsychotic drug pimozide inhibits cell growth in prostate cancer through suppression of STAT3 activation

Wei Zhou, Ming-Kun Chen, Hao-Tao Yu, Zhi-Hong Zhong, Nan Cai, Guan-Zhong Chen, Ping Zhang, Jia-Jie Chen
Pages: 322-328
Published online on: 04 November 2015

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Article

Hepatitis B virus X protein activates Notch signaling by its effects on Notch1 and Notch4 in human hepatocellular carcinoma

Juan Gao, Yimin Xiong, Yan Wang, Yiming Wang, Guorong Zheng, Hualin Xu
Pages: 329-337
Published online on: 30 October 2015

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Article

The effect and mechanism of bufalin on regulating hepatocellular carcinoma cell invasion and metastasis via Wnt/β-catenin signaling pathway

Ji Qin Gai, Xia Sheng, Jian Min Qin, Kang Sun, Wei Zhao, Lei Ni
Pages: 338-348
Published online on: 18 November 2015

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Article

All-trans retinoic acid inhibits proliferation, migration, invasion and induces differentiation of hepa1-6 cells through reversing EMT in vitro

Jiejie Cui, Mengjia Gong, Yun He, Qilin Li, Tongchuan He, Yang Bi
Pages: 349-357
Published online on: 06 November 2015

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Article

Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression

Yan Duan, Winnie Wong, Sonja Courtney Chua, Hwee Lin Wee, Seng Gee Lim, Boon Tin Chua, Han Kiat Ho
Pages: 358-366
Published online on: 13 November 2015

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Article

Differential regulation and synthetic lethality of exclusive RB1 and CDKN2A mutations in lung cancer

Nayoung Kim, Mee Song, Somin Kim, Yujeong Seo, Yonghwan Kim, Sukjoon Yoon
Pages: 367-375
Published online on: 20 November 2015

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Article

Gambogic acid induces apoptosis and sensitizes TRAIL-mediated apoptosis through downregulation of cFLIPL in renal carcinoma Caki cells

Ji Hoon Jang, Joo-Young Kim, Eon-Gi Sung, Eun-Ae Kim, Tae-Jin Lee
Pages: 376-384
Published online on: 18 November 2015

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Article

A novel curcumin derivative increases the cytotoxicity of raloxifene in estrogen receptor-negative breast cancer cell lines

Sebastien Taurin, Mhairi Nimick, Lesley Larsen, Rhonda J. Rosengren
Pages: 385-398
Published online on: 19 November 2015

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Article

Inhibition of glutamine utilization sensitizes lung cancer cells to apigenin-induced apoptosis resulting from metabolic and oxidative stress

Yoon-Mi Lee, Gibok Lee, Taek-In Oh, Byeong Mo Kim, Do-Wan Shim, Kwang-Ho Lee, Young Jun Kim, Beong Ou Lim, Ji-Hong Lim
Pages: 399-408
Published online on: 11 November 2015

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Article

Synergistic anticancer effects of cisplatin and histone deacetylase inhibitors (SAHA and TSA) on cholangiocarcinoma cell lines

Md. Ali Asgar, Gulsiri Senawong, Banchob Sripa, Thanaset Senawong
Pages: 409-420
Published online on: 09 November 2015

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Article

The mechanism of adenosine-mediated activation of lncRNA MEG3 and its antitumor effects in human hepatoma cells Corrigendum in /10.3892/ijo.2025.5765

Li-Xuan Liu, Wei Deng, Xiao-Tao Zhou, Rui-Pei Chen, Meng-Qi Xiang, Yi-Tian Guo, Ze-Jin Pu, Rui Li, Ge-Fei Wang, Ling-Fei Wu
Pages: 421-429
Published online on: 18 November 2015

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Journal Cover
September-2026 Volume 69 Issue 3

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The role of deubiquitinating enzymes and their inhibitors in esophageal carcinoma (Review)

Yu Zhao, Chenghai He, Kexin Chen, Nanting Sun, Ruonan He, Guodong Li
Article Number: 108
Published online on: 16 July 2026

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Correction Open Access

[Corrigendum] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 107
Published online on: 15 July 2026

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Article Open Access

Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma

Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
Article Number: 106
Published online on: 14 July 2026

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Article Open Access

YAP1‑mediated cytoplasmic‑nuclear translocation of SREBP2 promotes colorectal cancer via regulation of cholesterol metabolism

Luhui Zhong, Min Sun, Di Wu, Yulan Zeng, Min Zhou, Rui Gong, Feifei Gu, Kai Zhang, Xiaoyan Hu, Yue Hu
Article Number: 105
Published online on: 13 July 2026

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Review Open Access

Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)

Constantin N. Baxevanis, Savvas Stokidis, Sotirios P. Fortis, Maria Goulielmaki, Ourania E. Tsitsilonis, Angelos D. Gritzapis
Article Number: 104
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Article Number: 103
Published online on: 13 July 2026

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Review Open Access

The neural stem cell‑NSCLC axis: Molecular drivers, microenvironment crosstalk and emerging therapies (Review)

Yanling Xu, Hanmei Duan, Peng Lu, Feng Liu
Article Number: 102
Published online on: 10 July 2026

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Review Open Access

TGF‑β1 in cancer: From tumour suppressor to promoter, molecular mechanisms, and precision therapeutic strategies (Review)

Chao Huang
Article Number: 101
Published online on: 10 July 2026

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Article Open Access

T‑box transcription factor 15 regulated by methyltransferase‑like 3‑mediated N6‑methyladenosine modification promotes immune escape and progression of gastric cancer by activating matrix metalloproteinase 14 transcription

Hongsai Hu, Rong He, Minji Liu, Xuli Liu, Qiongjia Ai, Min Chen, Qian Wang, Wenhui Chen, Weiming Qu
Article Number: 100
Published online on: 09 July 2026

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Review Open Access

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review)

Bo Zhang, Lihan Shang, Ziyu Kuang, Chaoran Wang, Bingsheng Sun, Fanming Kong
Article Number: 99
Published online on: 09 July 2026

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Review Open Access

New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review)

Yuxiao Zhen, Weibo Hu, Shanshan Dong, Bochang Wang, Jian Shen, Leyuan Ding, Lifeng Li, Hailong An, Xuzhao Wang, Yafei Chen
Article Number: 98
Published online on: 09 July 2026

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Retraction Open Access

[Retracted] Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Article Number: 97
Published online on: 06 July 2026

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October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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