|
1
|
Wang Y and Jiang T: Understanding high
grade glioma: Molecular mechanism, therapy and comprehensive
management. Cancer Lett. 331:139–146. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Stupp R, Hegi ME, Mason WP, van den Bent
MJ, Taphoorn MJ, Janzer RC, Ludwin SK, Allgeier A, Fisher B,
Belanger K, et al; European Organisation for Research and Treatment
of Cancer Brain Tumour and Radiation Oncology Groups; National
Cancer Institute of Canada Clinical Trials Group. Effects of
radiotherapy with concomitant and adjuvant temozolomide versus
radiotherapy alone on survival in glioblastoma in a randomised
phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet
Oncol. 10:459–466. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Wen PY and Kesari S: Malignant gliomas in
adults. N Engl J Med. 359:492–507. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Wilusz JE, Sunwoo H and Spector DL: Long
noncoding RNAs: Functional surprises from the RNA world. Genes Dev.
23:1494–1504. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Nagano T and Fraser P: No-nonsense
functions for long noncoding RNAs. Cell. 145:178–181. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
6
|
Wu Y, Zhang L, Zhang L, Wang Y, Li H, Ren
X, Wei F, Yu W, Liu T, Wang X, et al: Long non-coding RNA HOTAIR
promotes tumor cell invasion and metastasis by recruiting EZH2 and
repressing E-cadherin in oral squamous cell carcinoma. Int J Oncol.
46:2586–2594. 2015.PubMed/NCBI
|
|
7
|
Wang Y, Chen W, Yang C, Wu W, Wu S, Qin X
and Li X: Long non-coding RNA UCA1a (CUDR) promotes proliferation
and tumorigenesis of bladder cancer. Int J Oncol. 41:276–284.
2012.PubMed/NCBI
|
|
8
|
Ørom UA, Derrien T, Beringer M, Gumireddy
K, Gardini A, Bussotti G, Lai F, Zytnicki M, Notredame C, Huang Q,
et al: Long noncoding RNAs with enhancer-like function in human
cells. Cell. 143:46–58. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Tian D, Sun S and Lee JT: The long
noncoding RNA, Jpx, is a molecular switch for X chromosome
inactivation. Cell. 143:390–403. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Kobayashi S, Wagatsuma H, Ono R, Ichikawa
H, Yamazaki M, Tashiro H, Aisaka K, Miyoshi N, Kohda T, Ogura A, et
al: Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed
imprinted genes closely located to the maternally expressed
imprinted genes: Mouse Meg3/Gtl2 and human MEG3. Genes Cells.
5:1029–1037. 2000. View Article : Google Scholar
|
|
11
|
Anwar SL, Krech T, Hasemeier B, Schipper
E, Schweitzer N, Vogel A, Kreipe H and Lehmann U: Loss of
imprinting and allelic switching at the DLK1-MEG3 locus in human
hepatocellular carcinoma. PLoS One. 7:e494622012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Astuti D, Latif F, Wagner K, Gentle D,
Cooper WN, Catchpoole D, Grundy R, Ferguson-Smith AC and Maher ER:
Epigenetic alteration at the DLK1-GTL2 imprinted domain in human
neoplasia: Analysis of neuroblastoma, phaeochromocytoma and Wilms'
tumour. Br J Cancer. 92:1574–1580. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Gejman R, Batista DL, Zhong Y, Zhou Y,
Zhang X, Swearingen B, Stratakis CA, Hedley-Whyte ET and Klibanski
A: Selective loss of MEG3 expression and intergenic differentially
methylated region hypermethylation in the MEG3/DLK1 locus in human
clinically nonfunctioning pituitary adenomas. J Clin Endocrinol
Metab. 93:4119–4125. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Zhou Y, Zhong Y, Wang Y, Zhang X, Batista
DL, Gejman R, Ansell PJ, Zhao J, Weng C and Klibanski A: Activation
of p53 by MEG3 non-coding RNA. J Biol Chem. 282:24731–24742. 2007.
View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Sheng X and Li J, Yang L, Chen Z, Zhao Q,
Tan L, Zhou Y and Li J: Promoter hypermethylation influences the
suppressive role of maternally expressed 3, a long non-coding RNA,
in the development of epithelial ovarian cancer. Oncol Rep.
32:277–285. 2014.PubMed/NCBI
|
|
16
|
Hervouet E, Vallette FM and Cartron PF:
Impact of the DNA methyltransferases expression on the methylation
status of apoptosis-associated genes in glioblastoma multiforme.
Cell Death Dis. 1:e82010. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Braconi C, Kogure T, Valeri N, Huang N,
Nuovo G, Costinean S, Negrini M, Miotto E, Croce CM and Patel T:
microRNA-29 can regulate expression of the long non-coding RNA gene
MEG3 in hepatocellular cancer. Oncogene. 30:4750–4756. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Furnari FB, Fenton T, Bachoo RM, Mukasa A,
Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, et al:
Malignant astrocytic glioma: Genetics, biology, and paths to
treatment. Genes Dev. 21:2683–2710. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Zhou Y, Zhang X and Klibanski A: MEG3
noncoding RNA: A tumor suppressor. J Mol Endocrinol. 48:R45–R53.
2012. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Yan J, Guo X, Xia J, Shan T, Gu C, Liang
Z, Zhao W and Jin S: MiR-148a regulates MEG3 in gastric cancer by
targeting DNA methyltransferase 1. Med Oncol. 31:8792014.
View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Zhang X, Gejman R, Mahta A, Zhong Y, Rice
KA, Zhou Y, Cheunsuchon P, Louis DN and Klibanski A: Maternally
expressed gene 3, an imprinted noncoding RNA gene, is associated
with meningioma pathogenesis and progression. Cancer Res.
70:2350–2358. 2010. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Zhao J, Dahle D, Zhou Y, Zhang X and
Klibanski A: Hyper-methylation of the promoter region is associated
with the loss of MEG3 gene expression in human pituitary tumors. J
Clin Endocrinol Metab. 90:2179–2186. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Kuo HK, Griffith JD and Kreuzer KN:
5-Azacytidine induced methyltransferase-DNA adducts block DNA
replication in vivo. Cancer Res. 67:8248–8254. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Lengauer C, Kinzler KW and Vogelstein B:
DNA methylation and genetic instability in colorectal cancer cells.
Proc Natl Acad Sci USA. 94:2545–2550. 1997. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Tsai HC, Li H, Van Neste L, Cai Y, Robert
C, Rassool FV, Shin JJ, Harbom KM, Beaty R, Pappou E, et al:
Transient low doses of DNA-demethylating agents exert durable
antitumor effects on hematological and epithelial tumor cells.
Cancer Cell. 21:430–446. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang P, Ren Z and Sun P: Overexpression of
the long non-coding RNA MEG3 impairs in vitro glioma cell
proliferation. J Cell Biochem. 113:1868–1874. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
27
|
Jurkowska RZ, Jurkowski TP and Jeltsch A:
Structure and function of mammalian DNA methyltransferases.
ChemBioChem. 12:206–222. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kreth S, Thon N, Eigenbrod S, Lutz J,
Ledderose C, Egensperger R, Tonn JC, Kretzschmar HA, Hinske LC and
Kreth FW: O-methylguanine-DNA methyltransferase (MGMT) mRNA
expression predicts outcome in malignant glioma independent of MGMT
promoter methylation. PLoS One. 6:e171562011. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Nakagawa T, Kanai Y, Ushijima S, Kitamura
T, Kakizoe T and Hirohashi S: DNA hypermethylation on multiple CpG
islands associated with increased DNA methyltransferase DNMT1
protein expression during multistage urothelial carcinogenesis. J
Urol. 173:1767–1771. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
30
|
Saito Y, Kanai Y, Nakagawa T, Sakamoto M,
Saito H, Ishii H and Hirohashi S: Increased protein expression of
DNA methyltransferase (DNMT) 1 is significantly correlated with the
malignant potential and poor prognosis of human hepatocellular
carcinomas. Int J Cancer. 105:527–532. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Bian EB, Zhao B, Huang C, Wang H, Meng XM,
Wu BM, Ma TT, Zhang L, Lv XW and Li J: New advances of DNA
methylation in liver fibrosis, with special emphasis on the
crosstalk between microRNAs and DNA methylation machinery. Cell
Signal. 25:1837–1844. 2013. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Foltz G, Yoon JG, Lee H, Ryken TC,
Sibenaller Z, Ehrich M, Hood L and Madan A: DNA
methyltransferase-mediated transcriptional silencing in malignant
glioma: A combined whole-genome microarray and promoter array
analysis. Oncogene. 28:2667–2677. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Vogelstein B, Lane D and Levine AJ:
Surfing the p53 network. Nature. 408:307–310. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
34
|
Lu KH, Li W, Liu XH, Sun M, Zhang ML, Wu
WQ, Xie WP and Hou YY: Long non-coding RNA MEG3 inhibits NSCLC
cells proliferation and induces apoptosis by affecting p53
expression. BMC Cancer. 13:4612013. View Article : Google Scholar : PubMed/NCBI
|
|
35
|
Zhang X, Rice K, Wang Y, Chen W, Zhong Y,
Nakayama Y, Zhou Y and Klibanski A: Maternally expressed gene 3
(MEG3) noncoding ribonucleic acid: Isoform structure, expression,
and functions. Endocrinology. 151:939–947. 2010. View Article : Google Scholar :
|
