Journal Articles

Notch and Wnt signaling pathway in cancer: Crucial role and potential therapeutic targets (Review)

Yu-Feng Xiao, Xin Yong, Bo Tang, Yong Qin, Jian-Wei Zhang, Dan Zhang, Rui Xie, Shi-Ming Yang

Pages: 437-449 Published online on: 07 December 2015
Open Access

Tumor-suppressive microRNA-29 family inhibits cancer cell migration and invasion directly targeting LOXL2 in lung squamous cell carcinoma

Keiko Mizuno, Naohiko Seki, Hiroko Mataki, Ryosuke Matsushita, Kazuto Kamikawaji, Tomohiro Kumamoto, Koichi Takagi, Yusuke Goto, Rika Nishikawa, Mayuko Kato, Hideki Enokida, Masayuki Nakagawa, Hiromasa Inoue

Pages: 450-460 Published online on: 14 December 2015
Open Access

Evaluation of a novel type of imaging probe based on a recombinant bivalent mini-antibody construct for detection of CD44v6-expressing squamous cell carcinoma

Anna-Karin Haylock, Diana Spiegelberg, Anja C. Mortensen, Ram K. Selvaraju, Johan Nilvebrant, Olof Eriksson, Vladimir Tolmachev, Marika V. Nestor

Pages: 461-470 Published online on: 14 December 2015
Open Access

PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer

Li-Xu Yan, Yan-Hui Liu, Jian-Wen Xiang, Qi-Nian Wu, Lei-Bo Xu, Xin-Lan Luo, Xiao-Lan Zhu, Chao Liu, Fang-Ping Xu, Dong-Lan Luo, Ping Mei, Jie Xu, Ke-Ping Zhang, Jie Chen

Pages: 471-484 Published online on: 10 December 2015
Open Access

Identification of miR-15b as a transformation-related factor in mantle cell lymphoma

Fumiko Arakawa, Yoshizo Kimura, Noriaki Yoshida, Hiroaki Miyoshi, Atushi Doi, Kaori Yasuda, Kazutaka Nakajima, Junichi Kiyasu, Daisuke Niino, Yasuo Sugita, Kosuke Tashiro, Satoru Kuhara, Masao Seto, Koichi Ohshima

Pages: 485-492 Published online on: 15 December 2015
Open Access

Treatment with cyclophosphamide supported by various dendritic cell-based vaccines induces diversification in CD4+ T cell response against MC38 colon carcinoma

Justyna Wojas-Turek, Agnieszka Szczygieł, Jagoda Kicielińska, Joanna Rossowska, Egbert Piasecki, Elżbieta Pajtasz-Piasecka

Pages: 493-505 Published online on: 07 December 2015
Open Access

CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas

Kentaro Nakayama, Mohammed Tanjimur Rahman, Munmun Rahman, Kohei Nakamura, Masako Ishikawa, Hiroshi Katagiri, Emi Sato, Tomoka Ishibashi, Kouji Iida, Noriyuki Ishikawa, Satoru Kyo

Pages: 506-516 Published online on: 26 November 2015

Concentration-dependent radiosensitizing effect of docetaxel in esophageal squamous cell carcinoma cells

Shohei Miyanaga, Itasu Ninomiya, Tomoya Tsukada, Koichi Okamoto, Shinichi Harada, Shinichi Nakanuma, Seisho Sakai, Isamu Makino, Jun Kinoshita, Hironori Hayashi, Keishi Nakamura, Katsunobu Oyama, Hisatoshi Nakagawara, Tomoharu Miyashita, Hidehiro Tajima, Hiroyuki Takamura, Sachio Fushida, Tetsuo Ohta

Pages: 517-524 Published online on: 14 December 2015

Establishment and evaluation of a new highly metastatic tumor cell line 5a-D-Luc-ZsGreen expressing both luciferase and green fluorescent protein

Hitomi Sudo, Atsushi B. Tsuji, Aya Sugyo, Hiroyuki Takuwa, Kazuto Masamoto, Yutaka Tomita, Norihiro Suzuki, Takeshi Imamura, Mitsuru Koizumi, Tsuneo Saga

Pages: 525-532 Published online on: 18 December 2015

Epigenetic regulation of proliferation and invasion in hepatocellular carcinoma cells by CBP/p300 histone acetyltransferase activity

Yuji Inagaki, Katsuya Shiraki, Kazushi Sugimoto, Takazumi Yada, Masahiko Tameda, Suguru Ogura, Norihiko Yamamoto, Yoshiyuki Takei, Masaaki Ito

Pages: 533-540 Published online on: 11 December 2015

MicroRNA-200b inhibits the growth and metastasis of glioma cells via targeting ZEB2

Jian Li, Jian Yuan, Xianrui Yuan, Jie Zhao, Zhiping Zhang, Ling Weng, Jingping Liu

Pages: 541-550 Published online on: 26 November 2015

Advanced endoscopic features of ulcerative colitis-associated neoplasias: Quantification of autofluorescence imaging

Shinichiro Yoshioka, Keiichi Mitsuyama, Hidetoshi Takedatsu, Kotaro Kuwaki, Ryosuke Yamauchi, Hiroshi Yamasaki, Shuhei Fukunaga, Jun Akiba, Tetsushi Kinugasa, Yoshito Akagi, Osamu Tsuruta, Takuji Torimura

Pages: 551-558 Published online on: 09 December 2015

Sulforaphane reverses chemo-resistance to temozolomide in glioblastoma cells by NF-κB-dependent pathway downregulating MGMT expression

Fengming Lan, Yang Yang, Jing Han, Qiaoli Wu, Huiming Yu, Xiao Yue

Pages: 559-568 Published online on: 27 November 2015

Cancer/testis antigen NY-SAR-35 enhances cell proliferation, migration, and invasion

Myung-Ha Song, Ye-Rin Kim, Jun-Won Lee, Chang-Hun Lee, Sang-Yull Lee

Pages: 569-576 Published online on: 24 November 2015

miR-512-5p induces apoptosis and inhibits glycolysis by targeting p21 in non-small cell lung cancer cells

Kaili Chu, Guanghui Gao, Xiufang Yang, Shengxiang Ren, Yao Li, Hai Wu, Yan Huang, Caicun Zhou

Pages: 577-586 Published online on: 07 December 2015

Molecular basis of antibody binding to mucin glycopeptides in lung cancer

Jin Qu, Hongtao Yu, Fenge Li, Chunlei Zhang, Ahmad Trad, Cory Brooks, Bin Zhang, Ting Gong, Zhi Guo, Yunsen Li, Govind Ragupathi, Yanyan Lou, Patrick Hwu, Wei Huang, Dapeng Zhou

Pages: 587-594 Published online on: 18 December 2015

N-cadherin promotes epithelial-mesenchymal transition and cancer stem cell-like traits via ErbB signaling in prostate cancer cells

Min Wang, Dong Ren, Wei Guo, Shuai Huang, Zeyu Wang, Qiji Li, Hong Du, Libing Song, Xinsheng Peng

Pages: 595-606 Published online on: 26 November 2015

Overexpression of TMOD1 is associated with enhanced regional lymph node metastasis in human oral cancer

Toshikazu Suzuki, Atsushi Kasamatsu, Isao Miyamoto, Tomoaki Saito, Morihiro Higo, Yosuke Endo-Sakamoto, Masashi Shiiba, Hideki Tanzawa, Katsuhiro Uzawa

Pages: 607-612 Published online on: 22 December 2015

SIRT2 mediates multidrug resistance in acute myelogenous leukemia cells via ERK1/2 signaling pathway

Hua Xu, Yuanye Li, Long Chen, Chijuan Wang, Qi Wang, Hairui Zhang, Yani Lin, Qinghua Li, Tianxiang Pang

Pages: 613-623 Published online on: 07 December 2015

Bioactive proanthocyanidins inhibit growth and induce apoptosis in human melanoma cells by decreasing the accumulation of β-catenin

Mudit Vaid, Tripti Singh, Ram Prasad, Santosh K. Katiyar

Pages: 624-634 Published online on: 10 December 2015

Correlation between levels of expression of minichromosome maintenance proteins, Ki-67 proliferation antigen and metallothionein I/II in laryngeal squamous cell cancer

Katarzyna Nowinska, Magdalena Chmielewska, Aleksandra Piotrowska, Bartosz Pula, Wojciech Pastuszewski, Tomasz Krecicki, Marzena Podhorska-Okołow, Maciej Zabel, Piotr Dziegiel

Pages: 635-645 Published online on: 27 November 2015

In vitro antitumor effects of two novel oligostilbenes, cis- and trans-suffruticosol D, isolated from Paeonia suffruticosa seeds

Nadin Marwan Almosnid, Ying Gao, Chunnian He, Hyo Sim Park, Elliot Altman

Pages: 646-656 Published online on: 26 November 2015

CD73 as a therapeutic target for pancreatic neuroendocrine tumor stem cells

Eriko Katsuta, Shinji Tanaka, Kaoru Mogushi, Shu Shimada, Yoshimitsu Akiyama, Arihiro Aihara, Satoshi Matsumura, Yusuke Mitsunori, Daisuke Ban, Takanori Ochiai, Atsushi Kudo, Hiroshi Fukamachi, Hiroshi Tanaka, Koh Nakayama, Shigeki Arii, Minoru Tanabe

Pages: 657-669 Published online on: 18 December 2015

Microarray expression profile analysis of long non-coding RNAs in pancreatic ductal adenocarcinoma

Yu Zhou, Bo Gong, Zhi-Lin Jiang, Shan Zhong, Xing-Chao Liu, Ke Dong, He-Shui Wu, Hong-Ji Yang, Shi-Kai Zhu

Pages: 670-680 Published online on: 15 December 2015

Lung cancer exosomes initiate global long non-coding RNA changes in mesenchymal stem cells

Shihua Wang, Xiaoxia Li, Rongjia Zhu, Qin Han, Robert Chunhua Zhao

Pages: 681-689 Published online on: 27 November 2015
Open Access

Identifying molecular subtypes in human colon cancer using gene expression and DNA methylation microarray data

Zhonglu Ren, Wenhui Wang, Jinming Li

Pages: 690-702 Published online on: 24 November 2015

Impaired gap junctions in human hepatocellular carcinoma limit intrinsic oxaliplatin chemosensitivity: A key role of connexin 26

Yan Yang, Jian Zhu, Na Zhang, Yu Zhao, Wan-Yun Li, Fu-You Zhao, Yu-Rong Ou, Shu-Kui Qin, Qiong Wu

Pages: 703-713 Published online on: 26 November 2015

RhoA is associated with invasion and poor prognosis in colorectal cancer

Dongjun Jeong, Soyoung Park, Hyungjoo Kim, Chang-Jin Kim, Tae Sung Ahn, Sang Byung Bae, Han Jo Kim, Tae Hyun Kim, Jungkyun Im, Moon Soo Lee, Hyog Young Kwon, Moo Jun Baek

Pages: 714-722 Published online on: 08 December 2015

Epigenetic repression of long non-coding RNA MEG3 mediated by DNMT1 represses the p53 pathway in gliomas

Jia Li, Er-Bao Bian, Xiao-Jun He, Chun-Chun Ma, Gang Zong, Hong-Liang Wang, Bing Zhao

Pages: 723-733 Published online on: 10 December 2015

A novel combination of oridonin and valproic acid in enhancement of apoptosis induction of HL-60 leukemia cells

Meiyan Shi, Xia Ren, Xidi Wang, Hengxiao Wang, Guoqiang Liu, Xiaofen Yuan, Shubo Zheng, Linchang Yu, Sufei Pan, Guanhua Song, Qiang Guo, Lianlian Li, Xiaoyu Zhang, Zhiyong Zhang, Huifang Ding, Guosheng Jiang

Pages: 734-746 Published online on: 15 December 2015

Aminoacyl-tRNA synthetase interacting multi-functional protein 1 attenuates liver fibrosis by inhibiting TGFβ signaling

Jongchan Ahn, Mi Kwon Son, Kyung Hee Jung, Kwangil Kim, Gi Jin Kim, Soo-Hong Lee, Soon-Sun Hong, Sang Gyu Park

Pages: 747-755 Published online on: 18 December 2015

Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation

Ming Zhao, Juan Fan, Yong Liu, Yanxin Yu, Jinhui Xu, Qinglian Wen, Jianwen Zhang, Shaozhi Fu, Biqiong Wang, Li Xiang, Jing Feng, Jingbo Wu, Linglin Yang

Pages: 756-764 Published online on: 17 December 2015

Downregulation of Nrf2 promotes radiation-induced apoptosis through Nrf2 mediated Notch signaling in non-small cell lung cancer cells

Qiuyue Zhao, Aihong Mao, Jiawei Yan, Chao Sun, Cuixia Di, Xin Zhou, Hongyan Li, Ruoshui Guo, Hong Zhang

Pages: 765-773 Published online on: 18 December 2015

Apoptotic activity of 5-fluorouracil in breast cancer cells transformed by low doses of ionizing α-particle radiation

Richard Ponce-Cusi, Gloria M. Calaf

Pages: 774-782 Published online on: 18 December 2015

Activation of pancreatic stellate cells involves an EMT-like process

Lei Tian, Zi-Peng Lu, Bao-Bao Cai, Liang-Tao Zhao, Dong Qian, Qing-Cheng Xu, Peng-Fei Wu, Yi Zhu, Jing-Jing Zhang, Qing Du, Yi Miao, Kui-Rong Jiang

Pages: 783-792 Published online on: 08 December 2015

Cytochrome P450 17A1 inhibitor abiraterone attenuates cellular growth of prostate cancer cells independently from androgen receptor signaling by modulation of oncogenic and apoptotic pathways

Hannah Grossebrummel, Tilmann Peter, Robert Mandelkow, Martin Weiss, Damian Muzzio, Uwe Zimmermann, Reinhard Walther, Federico Jensen, Cornelius Knabbe, Marek Zygmunt, Martin Burchardt, Matthias B. Stope

Pages: 793-800 Published online on: 27 November 2015

Targeting hedgehog signalling by arsenic trioxide reduces cell growth and induces apoptosis in rhabdomyosarcoma

Karen A. Boehme, Julian J. Zaborski, Rosa Riester, Sabrina K. Schweiss, Ulrike Hopp, Frank Traub, Torsten Kluba, Rupert Handgretinger, Sabine B. Schleicher

Pages: 801-812 Published online on: 15 December 2015

Antimycin A induces death of the human pulmonary fibroblast cells via ROS increase and GSH depletion

Woo Hyun Park, Bo Ra You

Pages: 813-820 Published online on: 07 December 2015

Ninjurin1 regulates lipopolysaccharide-induced inflammation through direct binding

Min Wook Shin, Sung-Jin Bae, Hee-Jun Wee, Hyo-Jong Lee, Bum Ju Ahn, Hoang Le, Eun Ji Lee, Ran Hee Kim, Hye Shin Lee, Ji Hae Seo, Ji-Hyeon Park, Kyu-Won Kim

Pages: 821-828 Published online on: 15 December 2015

Decreased expression of the plasminogen activator inhibitor type 1 is involved in degradation of extracellular matrix surrounding cervical cancer stem cells

Masakazu Sato, Kei Kawana, Katsuyuki Adachi, Asaha Fujimoto, Mitsuyo Yoshida, Hiroe Nakamura, Haruka Nishida, Tomoko Inoue, Ayumi Taguchi, Juri Takahashi, Satoko Kojima, Aki Yamashita, Kensuke Tomio, Takeshi Nagamatsu, Osamu Wada-Hiraike, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii

Pages: 829-835 Published online on: 09 December 2015

Methylsulfonylmethane inhibits HER2 expression through STAT5b in breast cancer cells

Dong Young Kang, Pramod Darvin, Young Beom Yoo, Youn Hee Joung, Nipin Sp, Hyo Joo Byun, Young Mok Yang

Pages: 836-842 Published online on: 07 December 2015
Open Access

[Corrigendum] The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells

Jun Fujiwara, Yoshihiro Sowa, Mano Horinaka, Makoto Koyama, Miki Wakada, Tsuneharu Miki, Toshiyuki Sakai

Pages: 854-854 Published online on: 25 November 2015
Journal Cover

Cover Legend PDF

February 2016
Volume 48 Issue 2

Print ISSN: 1019-6439
Online ISSN: 1791-2423

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