Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Oncology Letters
      • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Biomedical Reports
      • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • Information for Authors
    • Information for Reviewers
    • Information for Librarians
    • Information for Advertisers
    • Conferences
  • Language Editing
Spandidos Publications Logo
  • About
    • About Spandidos
    • Aims and Scopes
    • Abstracting and Indexing
    • Editorial Policies
    • Reprints and Permissions
    • Job Opportunities
    • Terms and Conditions
    • Contact
  • Journals
    • All Journals
    • Biomedical Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Experimental and Therapeutic Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Epigenetics
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Functional Nutrition
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Molecular Medicine
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • International Journal of Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Medicine International
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular and Clinical Oncology
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Molecular Medicine Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Letters
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • Oncology Reports
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
    • World Academy of Sciences Journal
      • Information for Authors
      • Editorial Policies
      • Editorial Board
      • Aims and Scope
      • Abstracting and Indexing
      • Bibliographic Information
      • Archive
  • Articles
  • Information
    • For Authors
    • For Reviewers
    • For Librarians
    • For Advertisers
    • Conferences
  • Language Editing
Login Register Submit
  • This site uses cookies
  • You can change your cookie settings at any time by following the instructions in our Cookie Policy. To find out more, you may read our Privacy Policy.

    I agree
Search articles by DOI, keyword, author or affiliation
Search
Advanced Search
presentation
International Journal of Oncology
Join Editorial Board Propose a Special Issue
Print ISSN: 1019-6439 Online ISSN: 1791-2423
Journal Cover
April-2016 Volume 48 Issue 4

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

Journal Cover
April-2016 Volume 48 Issue 4

Full Size Image

Cover Legend PDF

Sign up for eToc alerts
Recommend to Library

  • Article
  • Citations
    • Cite This Article
    • Download Citation
    • Create Citation Alert
    • Remove Citation Alert
    • Cited By
  • Similar Articles
    • Related Articles (in Spandidos Publications)
    • Similar Articles (Google Scholar)
    • Similar Articles (PubMed)
  • Download PDF
  • Download XML
  • View XML
Article

The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma

Corrigendum in: /10.3892/ijo.2020.5131
Corrigendum in: /10.3892/ijo.2022.5318
  • Authors:
    • Long Li
    • Jihui Yu
    • Zhaoning Duan
    • Hong-Xing Dang
  • View Affiliations / Copyright

    Affiliations: Department of Physical Examination, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China, Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, P.R. China, Department of PICU, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing 400016, P.R. China
  • Pages: 1457-1466
    |
    Published online on: January 25, 2016
       https://doi.org/10.3892/ijo.2016.3355
  • Expand metrics +
Metrics: Total Views: 0 (Spandidos Publications: | PMC Statistics: )
Metrics: Total PDF Downloads: 0 (Spandidos Publications: | PMC Statistics: )
Cited By (CrossRef): 0 citations Loading Articles...

This article is mentioned in:



Abstract

We investigated the effect of nuclear factor of activated T cells c1 (NFATc1) on the growth and vascular generation of human ovarian carcinoma SKOV3 cell-transplanted tumors in nude mice and explored the possible underlying mechanism. NFATc1 siRNA was transfected into the SKOV3 cells, which were then subjected to immunofluorescence tests and real-time reverse transcription polymerase chain reaction (RT-PCR) to determine the transfection-induced inhibition rate. The tumor volumes in the nude mice in all groups were measured to determine the in vivo antitumor effect of NFATc1 siRNA. Immunohistochemical (IHC) methods were employed to detect NFATc1 expression in tumor tissue, combined with cytokeratin (CK) staining to label the epithelial origin of the tumor tissue. CD34 and podoplanin were used as markers for labeling microvessels and microlymphatic vessels, respectively. The densities of microvessels and microlymphatic vessels in each group were calculated and statistically analyzed. RT-PCR and western blotting were performed to detect the protein and mRNA expression levels of NFATc1, the ELR+ CXC chemokine interleukin (IL)-8, fibroblast growth factor-2 (FGF-2), and platelet-derived growth factor BB (PDGF BB) in xenografted tumor tissue in all groups. NFATc1 was highly expressed in tumor tissue in the control groups. The intervention group exhibited a tumor growth inhibition rate of 57.08% and presented a lower tumor weight and volume compared with the two control groups. In the control groups, the microvessel densities were 12.00±1.65 and 11.47±0.32, respectively, and the microlymphatic vessel densities were 10.03±0.96 and 9.95±1.12; these values were significantly higher than in the intervention group. RT-PCR and western blot shows that NFATc1 siRNA could markedly suppress the expression of IL-8, FGF-2 and PDGF BB at the mRNA and the protein level. In conclusion, it was shown that NFATc1 siRNA significantly suppresses the growth and vascular generation of SKOV3 human ovarian carcinoma cell-transplanted tumors subcutaneously xenografted into nude mice. The downregulation of the expression of IL-8, FGF-2 and PDGF BB may be one of the mechanisms underlying the above inhibitory effects.
View Figures

Figure 1

Figure 2

Figure 3

Figure 4

Figure 5

Figure 6

View References

1 

Naito T, Tanaka H, Naoe Y and Taniuchi I: Transcriptional control of T-cell development. Int Immunol. 23:661–668. 2011. View Article : Google Scholar : PubMed/NCBI

2 

Chen L, Glover JN, Hogan PG, Rao A and Harrison SC: Structure of the DNA-binding domains from NFAT, Fos and Jun bound specifically to DNA. Nature. 392:42–48. 1998. View Article : Google Scholar : PubMed/NCBI

3 

Jain J, McCaffrey PG, Valge-Archer VE and Rao A: Nuclear factor of activated T cells contains Fos and Jun. Nature. 356:801–804. 1992. View Article : Google Scholar : PubMed/NCBI

4 

Bengsch B and Wherry EJ: The importance of cooperation: partnerless NFAT induces T cell exhaustion. Immunity. 42:203–205. 2015. View Article : Google Scholar : PubMed/NCBI

5 

Shaw JP, Utz PJ, Durand DB, Toole JJ, Emmel EA and Crabtree GR: Identification of a putative regulator of early T cell activation genes. Science. 241:202–205. 1988. View Article : Google Scholar : PubMed/NCBI

6 

Bai S and Kerppola TK: Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy. Mol Cell Biol. 31:3068–3080. 2011. View Article : Google Scholar : PubMed/NCBI

7 

Hanahan D and Weinberg RA: The hallmarks of cancer. Cell. 100:57–70. 2000. View Article : Google Scholar : PubMed/NCBI

8 

Chen NM, Singh G, Koenig A, Liou GY, Storz P, Zhang JS, Regul L, Nagarajan S, Kühnemuth B, Johnsen SA, et al: NFATc1 links EGFR signaling to induction of Sox9 transcription and acinar-ductal transdifferentiation in the pancreas. Gastroenterology. 148:1024–1034.e9. 2015. View Article : Google Scholar : PubMed/NCBI

9 

Hashizume M, Hayakawa N and Mihara M: IL-6 trans-signalling directly induces RANKL on fibroblast-like synovial cells and is involved in RANKL induction by TNF-alpha and IL-17. Rheumatology (Oxford). 47:1635–1640. 2008. View Article : Google Scholar

10 

Wang S, Kang X, Cao S, Cheng H, Wang D and Geng J: Calcineurin/NFATc1 pathway contributes to cell proliferation in hepatocellular carcinoma. Dig Dis Sci. 57:3184–3188. 2012. View Article : Google Scholar : PubMed/NCBI

11 

Beals CR, Sheridan CM, Turck CW, Gardner P and Crabtree GR: Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3. Science. 275:1930–1934. 1997. View Article : Google Scholar : PubMed/NCBI

12 

Köenig A, Linhart T, Schlengemann K, Reutlinger K, Wegele J, Adler G, Singh G, Hofmann L, Kunsch S, Büch T, et al: NFAT-induced histone acetylation relay switch promotes c-Myc-dependent growth in pancreatic cancer cells. Gastroenterology. 138:1189–1199.e1-2. 2010. View Article : Google Scholar

13 

Neal JW and Clipstone NA: A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts. J Biol Chem. 278:17246–17254. 2003. View Article : Google Scholar : PubMed/NCBI

14 

Zhang SD, McCrudden CM, Meng C, Lin Y and Kwok HF: The significance of combining VEGFA, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab. Onco Targets Ther. 8:835–843. 2015.PubMed/NCBI

15 

Wu B, Baldwin HS and Zhou B: Nfatc1 directs the endocardial progenitor cells to make heart valve primordium. Trends Cardiovasc Med. 23:294–300. 2013. View Article : Google Scholar : PubMed/NCBI

16 

Wu B, Wang Y, Lui W, Langworthy M, Tompkins KL, Hatzopoulos AK, Baldwin HS and Zhou B: Nfatc1 coordinates valve endocardial cell lineage development required for heart valve formation. Circ Res. 109:183–192. 2011. View Article : Google Scholar : PubMed/NCBI

17 

Adinolfi E, Raffaghello L, Giuliani AL, Cavazzini L, Capece M, Chiozzi P, Bianchi G, Kroemer G, Pistoia V and Di Virgilio F: Expression of P2X7 receptor increases in vivo tumor growth. Cancer Res. 72:2957–2969. 2012. View Article : Google Scholar : PubMed/NCBI

18 

Shoemaker LD, Fuentes LF, Santiago SM, Allen BM, Cook DJ, Steinberg GK and Chang SD: Human brain arteriovenous malformations express lymphatic-associated genes. Ann Clin Transl Neurol. 1:982–995. 2014. View Article : Google Scholar

19 

Chen HM, Tsai CH and Hung WC: Foretinib inhibits angiogenesis, lymphangiogenesis and tumor growth of pancreatic cancer in vivo by decreasing VEGFR-2/3 and TIE-2 signaling. Oncotarget. 6:14940–14952. 2015. View Article : Google Scholar : PubMed/NCBI

20 

Kähärä J and Lähdesmäki H: Evaluating a linear k-mer model for protein-DNA interactions using high-throughput SELEX data. BMC Bioinformatics. 14(Suppl 10): S22013.

21 

Kulkarni RM, Greenberg JM and Akeson AL: NFATc1 regulates lymphatic endothelial development. Mech Dev. 126:350–365. 2009. View Article : Google Scholar : PubMed/NCBI

22 

Norrmén C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, et al: FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 185:439–457. 2009. View Article : Google Scholar : PubMed/NCBI

23 

Lee JH, Bhang DH, Beede A, Huang TL, Stripp BR, Bloch KD, Wagers AJ, Tseng YH, Ryeom S and Kim CF: Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis. Cell. 156:440–455. 2014. View Article : Google Scholar : PubMed/NCBI

24 

Jang GH, Park IS, Yang JH, Bischoff J and Lee YM: Differential function of genes regulated by VEGF-NFATc1 signaling pathway in migration of pulmonary valve endothelial cells. FEBS Lett. 584:141–146. 2010. View Article : Google Scholar :

25 

Combs MD and Yutzey KE: VEGF and RANKL regulation of NFATc1 in heart valve development. Circ Res. 105:565–574. 2009. View Article : Google Scholar : PubMed/NCBI

26 

Li WH, Qiu Y, Zhang HQ, Tian XX and Fang WG: P2Y2 Receptor and EGFR cooperate to promote prostate cancer cell invasion via ERK1/2 pathway. PLoS One. 10:e01331652015. View Article : Google Scholar : PubMed/NCBI

27 

Moldobaeva A, Baek A, Eldridge L and Wagner EM: Differential activity of pro-angiogenic CXC chemokines. Microvasc Res. 80:18–22. 2010. View Article : Google Scholar : PubMed/NCBI

28 

Joimel U, Gest C, Soria J, Pritchard LL, Alexandre J, Laurent M, Blot E, Cazin L, Vannier JP, Varin R, et al: Stimulation of angiogenesis resulting from cooperation between macrophages and MDA-MB-231 breast cancer cells: Proposed molecular mechanism and effect of tetrathiomolybdate. BMC Cancer. 10:3752010. View Article : Google Scholar : PubMed/NCBI

29 

Sarmiento J, Shumate C, Suetomi K, Ravindran A, Villegas L, Rajarathnam K and Navarro J: Diverging mechanisms of activation of chemokine receptors revealed by novel chemokine agonists. PLoS One. 6:e279672011. View Article : Google Scholar : PubMed/NCBI

30 

Rabquer BJ, Tsou PS, Hou Y, Thirunavukkarasu E, Haines GK III, Impens AJ, Phillips K, Kahaleh B, Seibold JR and Koch AE: Dysregulated expression of MIG/CXCL9, IP-10/CXCL10 and CXCL16 and their receptors in systemic sclerosis. Arthritis Res Ther. 13:R182011. View Article : Google Scholar : PubMed/NCBI

31 

Caoa R, Jia H, Fenga N, et al: Collaborative interplay between FGF-2 and VEGF-C promotes lymphangiogenesis and metastasis. PNAS. 109:15894–15899. 2012. View Article : Google Scholar

32 

Cao R1, Björndahl MA, Religa P, et al: PDGF-BB induces intratumoral lymphangiogenesis and promotes lymphatic metastasis. Cancer Cell. 6:333–345. 2004. View Article : Google Scholar : PubMed/NCBI

33 

Andrés G1, Leali D, Mitola S, et al: A pro-inflammatory signature mediates FGF2-induced angiogenesis. Molecular Medicine. 13:2083–2108. 2009.

34 

Chang LK, Garcia-Cardeña G, Farnebo F, Fannon M, Chen EJ, Butterfield C, Moses MA, Mulligan RC, Folkman J and Kaipainen A: Dose-dependent response of FGF-2 for lymhangiongenesis. Proc Natl Acad Sci USA. 101:11658–11663. 2004. View Article : Google Scholar

35 

Schoppmann SF, Alidzanovic L, Schultheis A, Perkmann T, Brostjan C and Birner P: Thrombocytes correlate with lymphangiogenesis in human esophageal cancer and mediate growth of lymphatic endothelial cells in vitro. PLoS One. 8:e669412013. View Article : Google Scholar :

36 

Tung HC, Lee FY, Wang SS, Tsai MH, Lee JY, Huo TI, Huang HC, Chuang CL, Lin HC and Lee SD: The beneficial effects of P2X7 antagonism in rats with bile duct ligation-induced cirrhosis. PLoS One. 10:e01246542015. View Article : Google Scholar : PubMed/NCBI

37 

Zhao Y, Wang Y, Wang Q, Liu Z, Liu Q and Deng X: Hepatic stellate cells produce vascular endothelial growth factor via phospho-p44/42 mitogen-activated protein kinase/cyclooxygenase-2 pathway. Mol Cell Biochem. 359:217–223. 2012. View Article : Google Scholar

Related Articles

  • Abstract
  • View
  • Download
  • Twitter
Copy and paste a formatted citation
Spandidos Publications style
Li L, Yu J, Duan Z and Dang H: The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318. Int J Oncol 48: 1457-1466, 2016.
APA
Li, L., Yu, J., Duan, Z., & Dang, H. (2016). The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318. International Journal of Oncology, 48, 1457-1466. https://doi.org/10.3892/ijo.2016.3355
MLA
Li, L., Yu, J., Duan, Z., Dang, H."The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318". International Journal of Oncology 48.4 (2016): 1457-1466.
Chicago
Li, L., Yu, J., Duan, Z., Dang, H."The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318". International Journal of Oncology 48, no. 4 (2016): 1457-1466. https://doi.org/10.3892/ijo.2016.3355
Copy and paste a formatted citation
x
Spandidos Publications style
Li L, Yu J, Duan Z and Dang H: The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318. Int J Oncol 48: 1457-1466, 2016.
APA
Li, L., Yu, J., Duan, Z., & Dang, H. (2016). The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318. International Journal of Oncology, 48, 1457-1466. https://doi.org/10.3892/ijo.2016.3355
MLA
Li, L., Yu, J., Duan, Z., Dang, H."The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318". International Journal of Oncology 48.4 (2016): 1457-1466.
Chicago
Li, L., Yu, J., Duan, Z., Dang, H."The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma Corrigendum in /10.3892/ijo.2020.5131 Corrigendum in /10.3892/ijo.2022.5318". International Journal of Oncology 48, no. 4 (2016): 1457-1466. https://doi.org/10.3892/ijo.2016.3355
Follow us
  • Twitter
  • LinkedIn
  • Facebook
About
  • Spandidos Publications
  • Careers
  • Cookie Policy
  • Privacy Policy
How can we help?
  • Help
  • Live Chat
  • Contact
  • Email to our Support Team