Journal Articles

Open Access

Role of ribosomal protein mutations in tumor development (Review)

Kaveh M. Goudarzi, Mikael S. Lindström

Pages: 1313-1324 Published online on: 09 February 2016
Open Access

PET imaging of epidermal growth factor receptor expression in tumours using 89Zr-labelled ZEGFR:2377 affibody molecules

Javad Garousi, Ken G. Andersson, Bogdan Mitran, Marie-Louise Pichl, Stefan Ståhl, Anna Orlova, John Löfblom, Vladimir Tolmachev

Pages: 1325-1332 Published online on: 02 February 2016
Open Access

Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway

Xuefang Wu, Feng Luo, Jinbang Li, Xueyun Zhong, Kunping Liu

Pages: 1333-1340 Published online on: 26 January 2016
Open Access

Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil

Junpu Wang, Wanming Hu, Kuansong Wang, Jun Yu, Baihua Luo, Gengqiu Luo, Weiyuan Wang, Huiling Wang, Jinghe Li, Jifang Wen

Pages: 1341-1352 Published online on: 02 February 2016

New application of an old drug: Antitumor activity and mechanisms of doxycycline in small cell lung cancer

Sheng-Qi Wang, Bo-Xin Zhao, Yuan Liu, Ya-Tian Wang, Qian-Ying Liang, Yun Cai, Yun-Qi Zhang, Jiang-Hong Yang, Zhi-Hua Song, Guo-Feng Li

Pages: 1353-1360 Published online on: 04 February 2016
Open Access

Detection of metastatic tumors after γ-irradiation using longitudinal molecular imaging and gene expression profiling of metastatic tumor nodules

Su Jin Jang, Joo Hyun Kang, Yong Jin Lee, Kwang Il Kim, Tae Sup Lee, Jae Gol Choe, Sang Moo Lim

Pages: 1361-1368 Published online on: 08 February 2016
Open Access

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: Clinical and immunological data of a phase I/II clinical trial

Morena Antonilli, Hassan Rahimi, Valeria Visconti, Chiara Napoletano, Ilary Ruscito, Ilaria Grazia Zizzari, Salvatore Caponnetto, Giacomo Barchiesi, Roberta Iadarola, Luca Pierelli, Aurelia Rughetti, Filippo Bellati, Pierluigi Benedetti Panici, Marianna Nuti

Pages: 1369-1378 Published online on: 08 February 2016

Impaired mitophagy activates mtROS/HIF-1α interplay and increases cancer aggressiveness in gastric cancer cells under hypoxia

Masaaki Shida, Yoshihiko Kitajima, Jun Nakamura, Kazuyoshi Yanagihara, Koichi Baba, Kota Wakiyama, Hirokazu Noshiro

Pages: 1379-1390 Published online on: 26 January 2016

Overexpression of KiSS-1 reduces colorectal cancer cell invasion by downregulating MMP-9 via blocking PI3K/Akt/NF-κB signal pathway

Shaoqin Chen, Wei Chen, Xiang Zhang, Suyong Lin, Zhihua Chen

Pages: 1391-1398 Published online on: 02 February 2016

Downregulation of thymidylate synthase by RNAi molecules enhances the antitumor effect of pemetrexed in an orthotopic malignant mesothelioma xenograft mouse model

Amr S. Abu Lila, Chihiro Kato, Masakazu Fukushima, Cheng-Long Huang, Hiromi Wada, Tatsuhiro Ishida

Pages: 1399-1407 Published online on: 01 February 2016

Differential expression of CXCR4 and CXCR7 with various stem cell markers in paired human primary and recurrent glioblastomas

Charlotte Flüh, Kirsten Hattermann, H. Maximilian Mehdorn, Michael Synowitz, Janka Held-Feindt

Pages: 1408-1416 Published online on: 25 January 2016

Tyrosine receptor kinase B silencing inhibits anoikis‑resistance and improves anticancer efficiency of sorafenib in human renal cancer cells

Peng Zhang, Zengshu Xing, Xuechao Li, Yarong Song, Jun Zhao, Yajun Xiao, Yifei Xing

Pages: 1417-1425 Published online on: 25 January 2016

Piperlongumine exerts cytotoxic effects against cancer cells with mutant p53 proteins at least in part by restoring the biological functions of the tumor suppressor

Debasish Basak, Surendra R. Punganuru, Kalkunte S. Srivenugopal

Pages: 1426-1436 Published online on: 03 February 2016

Quantitative proteomic study of human prostate cancer cells with different metastatic potentials

Qun Li, Yilei Li, Yanying Wang, Zheng Cui, Lulu Gong, Zhigang Qu, Yanping Zhong, Jun Zhou, Ying Zhou, Yong Gao, Yulin Li

Pages: 1437-1446 Published online on: 04 February 2016

Fibulin-5 downregulates Ki-67 and inhibits proliferation and invasion of breast cancer cells

Yamina Mohamedi, Tania Fontanil, Laura Solares, Olivia Garcia-Suárez, Jorge García-Piqueras, Jose A. Vega, Santiago Cal, Alvaro J. Obaya

Pages: 1447-1456 Published online on: 17 February 2016

The effect of NFATc1 on vascular generation and the possible underlying mechanism in epithelial ovarian carcinoma

Long Li, Jihui Yu, Zhaoning Duan, Hong-Xing Dang

Pages: 1457-1466 Published online on: 25 January 2016

The preventative effect of Akt knockout on liver cancer through modulating NF-κB-regulated inflammation and Bad-related apoptosis signaling pathway

Bin Hu, Ming Sun, Jiajun Liu, Guolin Hong, Qin Lin

Pages: 1467-1476 Published online on: 08 February 2016

Regorafenib as a potential adjuvant chemotherapy agent in disseminated small colon cancer: Drug selection outcome of a novel screening system using nanoimprinting 3-dimensional culture with HCT116-RFP cells

Yukie Yoshii, Takako Furukawa, Hironori Aoyama, Naoya Adachi, Ming-Rong Zhang, Hidekatsu Wakizaka, Yasuhisa Fujibayashi, Tsuneo Saga

Pages: 1477-1484 Published online on: 28 January 2016

High-mobility group AT-hook protein 2 expression and its prognostic significance in MGMT methylated and unmethylated glioblastoma

Frank P. Schwarm, Florian Uhle, Anne Schänzer, Till Acker, Marco Stein, Marcus H.T. Reinges, Cornelia Weischer, Marcus A. Weigand, Eberhard Uhl, Malgorzata A. Kolodziej

Pages: 1485-1492 Published online on: 17 February 2016

Transcutaneous carbon dioxide suppresses epithelial-mesenchymal transition in oral squamous cell carcinoma

Eiji Iwata, Takumi Hasegawa, Daisuke Takeda, Takeshi Ueha, Teruya Kawamoto, Toshihiro Akisue, Yoshitada Sakai, Takahide Komori

Pages: 1493-1498 Published online on: 05 February 2016

Suppression of CD51 in pancreatic stellate cells inhibits tumor growth by reducing stroma and altering tumor-stromal interaction in pancreatic cancer

Kohei Horioka, Kenoki Ohuchida, Masafumi Sada, Biao Zheng, Taiki Moriyama, Hayato Fujita, Tatsuya Manabe, Takao Ohtsuka, Masaya Shimamoto, Tetsuyuki Miyazaki, Kazuhiro Mizumoto, Yoshinao Oda, Masafumi Nakamura

Pages: 1499-1508 Published online on: 03 February 2016

Lentiviral-mediated overexpression of long non-coding RNA GAS5 reduces invasion by mediating MMP2 expression and activity in human melanoma cells

Long Chen, Huixin Yang, Yanbin Xiao, Xiaoxia Tang, Yuqian Li, Qiaoqiao Han, Junping Fu, Yuye Yang, Yuechun Zhu

Pages: 1509-1518 Published online on: 04 February 2016

Triptolide decreases expression of latency-associated nuclear antigen 1 and reduces viral titers in Kaposi's sarcoma-associated and herpesvirus-related primary effusion lymphoma cells

Cong Long, Wei Guo, Heng Zhou, Jingchao Wang, Huan Wang, Xiaoping Sun

Pages: 1519-1530 Published online on: 25 January 2016

MicroRNA-301a promotes cell proliferation via PTEN targeting in Ewing's sarcoma cells

Masanori Kawano, Kazuhiro Tanaka, Ichiro Itonaga, Tatsuya Iwasaki, Hiroshi Tsumura

Pages: 1531-1540 Published online on: 05 February 2016

Upregulation of metastasis-associated PRL-3 initiates chordoma in zebrafish

Li Li, Hongshun Shi, Mingming Zhang, Xiaoling Guo, Fang Tong, Wenliang Zhang, Junyi Zhou, Haihe Wang, Shulan Yang

Pages: 1541-1552 Published online on: 29 January 2016

Suppression of lysyl-tRNA synthetase, KRS, causes incomplete epithelial-mesenchymal transition and ineffective cell‑extracellular matrix adhesion for migration

Seo Hee Nam, Minkyung Kang, Jihye Ryu, Hye-Jin Kim, Doyeun Kim, Dae Gyu Kim, Nam Hoon Kwon, Sunghoon Kim, Jung Weon Lee

Pages: 1553-1560 Published online on: 08 February 2016

Knockdown of B7-H6 inhibits tumor progression and enhances chemosensitivity in B-cell non-Hodgkin lymphoma

Feifei Wu, Jing Wang, Xiaoyan Ke

Pages: 1561-1570 Published online on: 17 February 2016

Genomic profiling of the genes on chromosome 3p in sporadic clear cell renal cell carcinoma

Yoshikazu Togo, Yoshie Yoshikawa, Toru Suzuki, Yoshiro Nakano, Akihiro Kanematsu, Masataka Zozumi, Michio Nojima, Seiichi Hirota, Shingo Yamamoto, Tomoko Hashimoto-Tamaoki

Pages: 1571-1580 Published online on: 17 February 2016

Placenta growth factor and neuropilin-1 collaborate in promoting melanoma aggressiveness

Elena Pagani, Federica Ruffini, Gian Carlo Antonini Cappellini, Alessandro Scoppola, Cristina Fortes, Paolo Marchetti, Grazia Graziani, Stefania D'Atri, Pedro Miguel Lacal

Pages: 1581-1589 Published online on: 29 January 2016

Long noncoding RNA AFAP1-AS1 indicates a poor prognosis of hepatocellular carcinoma and promotes cell proliferation and invasion via upregulation of the RhoA/Rac2 signaling

Jin-Yan Zhang, Ming-Zhe Weng, Fang-Bin Song, Yong-Gang Xu, Qi Liu, Jun-Yi Wu, Jun Qin, Tao Jin, Jun-Ming Xu

Pages: 1590-1598 Published online on: 08 February 2016

Differential microRNA expression profiling of mesothelioma and expression analysis of miR-1 and miR-214 in mesothelioma

Vishwa Jeet Amatya, Amany Sayed Mawas, Kei Kushitani, Mouchira M. Mohi El-Din, Yukio Takeshima

Pages: 1599-1607 Published online on: 26 January 2016

Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells

Ingo Lange, Julia Moschny, Kamilla Tamanyan, Manana Khutsishvili, Daniel Atha, Robert P. Borris, Dana-Lynn Koomoa

Pages: 1608-1616 Published online on: 03 February 2016

Gene expression profiling of microRNAs associated with UCA1 in bladder cancer cells

Xiaojuan Xie, Jingjing Pan, Liqiang Wei, Shouzhen Wu, Huilian Hou, Xu Li, Wei Chen

Pages: 1617-1627 Published online on: 25 January 2016

Ribosomal protein S15A promotes malignant transformation and predicts poor outcome in colorectal cancer through misregulation of p53 signaling pathway

Jingwen Chen, Ye Wei, Qingyang Feng, Li Ren, Guodong He, Wenju Chang, Dexiang Zhu, Tuo Yi, Qi Lin, Wentao Tang, Jianmin Xu, Xinyu Qin

Pages: 1628-1638 Published online on: 01 February 2016

Tripartite motif 16 inhibits hepatocellular carcinoma cell migration and invasion

Linlin Li, Lei Dong, Xiaotong Qu, Shi Jin, Xiupeng Lv, Guang Tan

Pages: 1639-1649 Published online on: 17 February 2016

E2F1 promotes tumor cell invasion and migration through regulating CD147 in prostate cancer

Yu-Xiang Liang, Jian-Ming Lu, Ru-Jun Mo, Hui-Chan He, Jian Xie, Fu-Neng Jiang, Zhuo-Yuan Lin, Yan-Ru Chen, Yong-Ding Wu, Hong-Wei Luo, Zheng Luo, Wei-De Zhong

Pages: 1650-1658 Published online on: 29 January 2016

Adrenomedullin in the growth modulation and differentiation of acute myeloid leukemia cells

Rosa Di Liddo, Deborah Bridi, Michele Gottardi, Sergio De Angeli, Claudio Grandi, Alessia Tasso, Thomas Bertalot, Giovanni Martinelli, Filippo Gherlinzoni, Maria Teresa Conconi

Pages: 1659-1669 Published online on: 02 February 2016

Agarol, an ergosterol derivative from Agaricus blazei, induces caspase-independent apoptosis in human cancer cells

Takamitsu Shimizu, Junya Kawai, Kenji Ouchi, Haruhisa Kikuchi, Yoshiteru Osima, Rikiishi Hidemi

Pages: 1670-1678 Published online on: 15 February 2016

Cellular apoptosis susceptibility (CAS) is overexpressed in thyroid carcinoma and maintains tumor cell growth: A potential link to the BRAFV600E mutation

Kerstin Holzer, Elisabeth Drucker, Scott Oliver, Juliane Winkler, Eva Eiteneuer, Esther Herpel, Kai Breuhahn, Stephan Singer

Pages: 1679-1687 Published online on: 09 February 2016

Overexpression of microRNA-5100 decreases the aggressive phenotype of pancreatic cancer cells by targeting PODXL

Yoshiro Chijiiwa, Taiki Moriyama, Kenoki Ohuchida, Toshinaga Nabae, Takao Ohtsuka, Yoshihiro Miyasaka, Hayato Fujita, Ryo Maeyama, Tatsuya Manabe, Atsushi Abe, Yusuke Mizuuchi, Yoshinao Oda, Kazuhiro Mizumoto, Masafumi Nakamura

Pages: 1688-1700 Published online on: 12 February 2016

Development of three-dimensional lung multicellular spheroids in air- and liquid-interface culture for the evaluation of anticancer therapeutics

Samantha A. Meenach, Alexandra N. Tsoras, Ronald C. McGarry, Heidi M. Mansour, J. Zach Hilt, Kimberly W. Anderson

Pages: 1701-1709 Published online on: 04 February 2016

Hsp90 inhibitor, BIIB021, induces apoptosis and autophagy by regulating mTOR-Ulk1 pathway in imatinib-sensitive and -resistant chronic myeloid leukemia cells

Wei He, Xiujin Ye, Xianbo Huang, Wen Lel, Liangshun You, Lei Wang, Xiaohui Chen, Wenbin Qian

Pages: 1710-1720 Published online on: 08 February 2016

The milk-derived hexapeptide PGPIPN inhibits the invasion and migration of human ovarian cancer cells by regulating the expression of MTA1 and NM23H1 genes

Mengjing Zhao, Cai Wei, Xue Yang, Juan Zhou, Jing Wang, Fang Gu, Ting Lei, Yide Qin

Pages: 1721-1729 Published online on: 12 February 2016

Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer

Bo Yin, Mo Zhang, Yu Zeng, Youqiang Li, Chao Zhang, Yongsheng Song

Pages: 1730-1736 Published online on: 17 February 2016

miR-17-92 plays an oncogenic role and conveys chemo-resistance to cisplatin in human prostate cancer cells

Peng Zhou, Liang Ma, Jun Zhou, Min Jiang, Enyu Rao, Yong Zhao, Feng Guo

Pages: 1737-1748 Published online on: 15 February 2016

Licochalcone B induces apoptosis of human oral squamous cell carcinoma through the extrinsic- and intrinsic-signaling pathways

Hana Oh, Goo Yoon, Jae-Cheon Shin, Seon-Min Park, Seung-Sik Cho, Jin Hyoung Cho, Mee-Hyun Lee, Kangdong Liu, Young Sik Cho, Jung-Il Chae, Jung-Hyun Shim

Pages: 1749-1757 Published online on: 01 February 2016
Journal Cover

Cover Legend PDF

April 2016
Volume 48 Issue 4

Print ISSN: 1019-6439
Online ISSN: 1791-2423

Sign up for eToc alerts

Recommend to Library

Full Size Image