|
1
|
Li Q, Chen P, Zeng Z, Liang F, Song Y,
Xiong F, Li X, Gong Z, Zhou M, Xiang B, et al: Yeast two-hybrid
screening identified WDR77 as a novel interacting partner of
TSC22D2. Tumor Biol. (In press).
|
|
2
|
Yoon CH, Rho SB, Kim ST, Kho S, Park J,
Jang IS, Woo S, Kim SS, Lee JH and Lee SH: Crucial role of TSC-22
in preventing the proteasomal degradation of p53 in cervical
cancer. PLoS One. 7:e420062012. View Article : Google Scholar : PubMed/NCBI
|
|
3
|
Choi SJ, Moon JH, Ahn YW, Ahn JH, Kim DU
and Han TH: Tsc-22 enhances TGF-beta signaling by associating with
Smad4 and induces erythroid cell differentiation. Mol Cell Biochem.
271:23–28. 2005. View Article : Google Scholar : PubMed/NCBI
|
|
4
|
Ayroldi E, Migliorati G, Bruscoli S,
Marchetti C, Zollo O, Cannarile L, D’Adamio F and Riccardi C:
Modulation of T-cell activation by the glucocorticoid-induced
leucine zipper factor via inhibition of nuclear factor kappaB.
Blood. 98:743–753. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
5
|
Ayroldi E, Petrillo MG, Bastianelli A,
Marchetti MC, Ronchetti S, Nocentini G, Ricciotti L, Cannarile L
and Riccardi C: L-GILZ binds p53 and MDM2 and suppresses tumor
growth through p53 activation in human cancer cells. Cell Death
Differ. 22:118–130. 2015. View Article : Google Scholar
|
|
6
|
Ayroldi E, Zollo O, Bastianelli A,
Marchetti C, Agostini M, Di Virgilio R and Riccardi C: GILZ
mediates the antiproliferative activity of glucocorticoids by
negative regulation of Ras signaling. J Clin Invest. 117:1605–1615.
2007. View
Article : Google Scholar : PubMed/NCBI
|
|
7
|
Christofk HR, Vander Heiden MG, Harris MH,
Ramanathan A, Gerszten RE, Wei R, Fleming MD, Schreiber SL and
Cantley LC: The M2 splice isoform of pyruvate kinase is important
for cancer metabolism and tumour growth. Nature. 452:230–233. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Anastasiou D, Yu Y, Israelsen WJ, Jiang
JK, Boxer MB, Hong BS, Tempel W, Dimov S, Shen M, Jha A, et al:
Pyruvate kinase M2 activators promote tetramer formation and
suppress tumorigenesis. Nat Chem Biol. 8:839–847. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Hitosugi T, Kang S, Vander Heiden MG,
Chung TW, Elf S, Lythgoe K, Dong S, Lonial S, Wang X, Chen GZ, et
al: Tyrosine phosphorylation inhibits PKM2 to promote the Warburg
effect and tumor growth. Sci Signal. 2:ra732009. View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Chen Z, Wang Z, Guo W, Zhang Z, Zhao F,
Zhao Y, Jia D, Ding J, Wang H, Yao M, et al: TRIM35 interacts with
pyruvate kinase isoform M2 to suppress the Warburg effect and
tumorigenicity in hepatocellular carcinoma. Oncogene. 34:3946–3956.
2015. View Article : Google Scholar
|
|
11
|
Chaneton B and Gottlieb E: Rocking cell
metabolism: Revised functions of the key glycolytic regulator PKM2
in cancer. Trends Biochem Sci. 37:309–316. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
12
|
Luo W and Semenza GL: Emerging roles of
PKM2 in cell metabolism and cancer progression. Trends Endocrinol
Metab. 23:560–566. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Lv L, Xu YP, Zhao D, Li FL, Wang W, Sasaki
N, Jiang Y, Zhou X, Li TT, Guan KL, et al: Mitogenic and oncogenic
stimulation of K433 acetylation promotes PKM2 protein kinase
activity and nuclear localization. Mol Cell. 52:340–352. 2013.
View Article : Google Scholar : PubMed/NCBI
|
|
14
|
Yang W, Zheng Y, Xia Y, Ji H, Chen X, Guo
F, Lyssiotis CA, Aldape K, Cantley LC and Lu Z: ERK1/2-dependent
phosphorylation and nuclear translocation of PKM2 promotes the
Warburg effect. Nat Cell Biol. 14:1295–1304. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Yang W, Xia Y, Hawke D, Li X, Liang J,
Xing D, Aldape K, Hunter T, Alfred Yung WK and Lu Z: PKM2
phosphorylates histone H3 and promotes gene transcription and
tumorigenesis. Cell. 150:685–696. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Yang W, Xia Y, Ji H, Zheng Y, Liang J,
Huang W, Gao X, Aldape K and Lu Z: Nuclear PKM2 regulates β-catenin
transactivation upon EGFR activation. Nature. 480:118–122. 2011.
View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Luo W, Hu H, Chang R, Zhong J, Knabel M,
O’Meally R, Cole RN, Pandey A and Semenza GL: Pyruvate kinase M2 is
a PHD3-stimulated coactivator for hypoxia-inducible factor 1. Cell.
145:732–744. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Lee J, Kim HK, Han YM and Kim J: Pyruvate
kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4
in regulating transcription. Int J Biochem Cell Biol. 40:1043–1054.
2008. View Article : Google Scholar : PubMed/NCBI
|
|
19
|
Lim J, Hao T, Shaw C, Patel AJ, Szabó G,
Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, et al: A
protein-protein interaction network for human inherited ataxias and
disorders of Purkinje cell degeneration. Cell. 125:801–814. 2006.
View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Landschulz WH, Johnson PF and McKnight SL:
The leucine zipper: A hypothetical structure common to a new class
of DNA binding proteins. Science. 240:1759–1764. 1988. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Kouzarides T and Ziff E: Leucine zippers
of fos, jun and GCN4 dictate dimerization specificity and thereby
control DNA binding. Nature. 340:568–571. 1989. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Busch SJ and Sassone-Corsi P: Dimers,
leucine zippers and DNA-binding domains. Trends Genet. 6:36–40.
1990. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Hashiguchi A, Hitachi K, Inui M,
Okabayashi K and Asashima M: TSC-box is essential for the nuclear
localization and antiproliferative effect of XTSC-22. Dev Growth
Differ. 49:197–204. 2007. View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Hino S, Kawamata H, Uchida D, Omotehara F,
Miwa Y, Begum NM, Yoshida H, Fujimori T and Sato M: Nuclear
translocation of TSC-22 (TGF-beta-stimulated clone-22) concomitant
with apoptosis: TSC-22 as a putative transcriptional regulator.
Biochem Biophys Res Commun. 278:659–664. 2000. View Article : Google Scholar : PubMed/NCBI
|
|
25
|
Nakamura M, Kitaura J, Enomoto Y, Lu Y,
Nishimura K, Isobe M, Ozaki K, Komeno Y, Nakahara F, Oki T, et al:
Transforming growth factor-β-stimulated clone-22 is a
negative-feedback regulator of Ras/Raf signaling: Implications for
tumorigenesis. Cancer Sci. 103:26–33. 2012. View Article : Google Scholar
|
|
26
|
Gluderer S, Brunner E, Germann M,
Jovaisaite V, Li C, Rentsch CA, Hafen E and Stocker H: Madm (Mlf1
adapter molecule) cooperates with Bunched A to promote growth in
Drosophila. J Biol. 9:92010. View
Article : Google Scholar : PubMed/NCBI
|
|
27
|
Kester HA, Blanchetot C, den Hertog J, van
der Saag PT and van der Burg B: Transforming growth
factor-beta-stimulated clone-22 is a member of a family of leucine
zipper proteins that can homo- and heterodimerize and has
transcriptional repressor activity. J Biol Chem. 274:27439–27447.
1999. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Gao X, Wang H, Yang JJ, Liu X and Liu ZR:
Pyruvate kinase M2 regulates gene transcription by acting as a
protein kinase. Mol Cell. 45:598–609. 2012. View Article : Google Scholar : PubMed/NCBI
|
|
29
|
Wang HJ, Hsieh YJ, Cheng WC, Lin CP, Lin
YS, Yang SF, Chen CC, Izumiya Y, Yu JS, Kung HJ, et al: JMJD5
regulates PKM2 nuclear translocation and reprograms HIF-1α-mediated
glucose metabolism. Proc Natl Acad Sci USA. 111:279–284. 2014.
View Article : Google Scholar
|
