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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Journals

International Journal of Molecular Medicine

International Journal of Molecular Medicine

International Journal of Molecular Medicine is an international journal devoted to molecular mechanisms of human disease.

International Journal of Oncology

International Journal of Oncology

International Journal of Oncology is an international journal devoted to oncology research and cancer treatment.

Molecular Medicine Reports

Molecular Medicine Reports

Covers molecular medicine topics such as pharmacology, pathology, genetics, neuroscience, infectious diseases, molecular cardiology, and molecular surgery.

Oncology Reports

Oncology Reports

Oncology Reports is an international journal devoted to fundamental and applied research in Oncology.

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine

Experimental and Therapeutic Medicine is an international journal devoted to laboratory and clinical medicine.

Oncology Letters

Oncology Letters

Oncology Letters is an international journal devoted to Experimental and Clinical Oncology.

Biomedical Reports

Biomedical Reports

Explores a wide range of biological and medical fields, including pharmacology, genetics, microbiology, neuroscience, and molecular cardiology.

Molecular and Clinical Oncology

Molecular and Clinical Oncology

International journal addressing all aspects of oncology research, from tumorigenesis and oncogenes to chemotherapy and metastasis.

World Academy of Sciences Journal

World Academy of Sciences Journal

Multidisciplinary open-access journal spanning biochemistry, genetics, neuroscience, environmental health, and synthetic biology.

International Journal of Functional Nutrition

International Journal of Functional Nutrition

Open-access journal combining biochemistry, pharmacology, immunology, and genetics to advance health through functional nutrition.

International Journal of Epigenetics

International Journal of Epigenetics

Publishes open-access research on using epigenetics to advance understanding and treatment of human disease.

Medicine International

Medicine International

An International Open Access Journal Devoted to General Medicine.

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Journal Cover
September-2016 Volume 49 Issue 3

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review

Neutrophils in cancer development and progression: Roles, mechanisms, and implications (Review)

Xu Zhang, Wen Zhang, Xiao Yuan, Min Fu, Hui Qian, Wenrong Xu
Pages: 857-867
Published online on: 07 July 2016

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Article Open Access

Phosphatidylinositol glycan anchor biosynthesis, class X containing complex promotes cancer cell proliferation through suppression of EHD2 and ZIC1, putative tumor suppressors

Makoto Nakakido, Kenji Tamura, Suyoun Chung, Koji Ueda, Risa Fujii, Kazuma Kiyotani, Yusuke Nakamura
Pages: 868-876
Published online on: 06 July 2016

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Article Open Access

Actin bundling by dynamin 2 and cortactin is implicated in cell migration by stabilizing filopodia in human non-small cell lung carcinoma cells

Hiroshi Yamada, Tetsuya Takeda, Hiroyuki Michiue, Tadashi Abe, Kohji Takei
Pages: 877-886
Published online on: 30 June 2016

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Article Open Access

Enhanced expression of semaphorin 3E is involved in the gastric cancer development

Ryuhei Maejima, Keiichi Tamai, Takeharu Shiroki, Misa Yokoyama, Rie Shibuya, Mao Nakamura, Kazunori Yamaguchi, Makoto Abue, Tomoyuki Oikawa, Tetsuya Noguchi, Koh Miura, Tsuneaki Fujiya, Ikuro Sato, Katsunori Iijima, Tooru Shimosegawa, Nobuyuki Tanaka, Kennichi Satoh
Pages: 887-894
Published online on: 30 June 2016

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Article Open Access

Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice

John Cha, M. Waheed Roomi, Tatiana Kalinovsky, Aleksandra Niedzwiecki, Matthias Rath
Pages: 895-902
Published online on: 01 July 2016

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Article Open Access

Overexpression of KH-type splicing regulatory protein regulates proliferation, migration, and implantation ability of osteosarcoma

Dumnoensun Pruksakorn, Pimpisa Teeyakasem, Jeerawan Klangjorhor, Parunya Chaiyawat, Jongkolnee Settakorn, Penchatr Diskul-Na-Ayudthaya, Daranee Chokchaichamnankit, Peraphan Pothacharoen, Chantragan Srisomsap
Pages: 903-912
Published online on: 04 July 2016

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Article Open Access

Protein signatures as potential surrogate biomarkers for stratification and prediction of treatment response in chronic myeloid leukemia patients

Ayodele A. Alaiya, Mahmoud Aljurf, Zakia Shinwari, Fahad Almohareb, Hafiz Malhan, Hazzaa Alzahrani, Tarek Owaidah, Jonathan Fox, Fahad Alsharif, Said Y. Mohamed, Walid Rasheed, Ghuzayel Aldawsari, Amr Hanbali, Syed Osman Ahmed, Naeem Chaudhri
Pages: 913-933
Published online on: 07 July 2016

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Article

Neuromedin B receptor antagonism inhibits migration, invasion, and epithelial-mesenchymal transition of breast cancer cells

Hyun-Joo Park, Mi-Kyoung Kim, Kyu-Sil Choi, Joo-Won Jeong, Soo-Kyung Bae, Hyung Joon Kim, Moon-Kyoung Bae
Pages: 934-942
Published online on: 30 June 2016

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Article

Long non-coding RNA HOTAIR modulates HLA-G expression by absorbing miR-148a in human cervical cancer Retraction in /10.3892/ijo.2024.5685

Jinbao Sun, Haipeng Chu, Jianghai Ji, Gaoxiang Huo, Qinglei Song, Xue Zhang
Pages: 943-952
Published online on: 30 June 2016

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Article

GLI inhibitor GANT61 kills melanoma cells and acts in synergy with obatoclax

Kateřina Vlčková, Jiri Réda, Lubica Ondrušová, Mohammad Krayem, Ghanem Ghanem, Jiri Vachtenheim
Pages: 953-960
Published online on: 01 July 2016

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Article

SPECT imaging of neuropilin receptor type-1 expression with 131I-labeled monoclonal antibody

Xiaofeng Dou, Jianghua Yan, Yafei Zhang, Peng Liu, Yizhen Jiang, Sha Lv, Fanwei Zeng, Xiaoli Chen, Shengyu Wang, Haipeng Zhang, Hua Wu, Hong Zhang, Lin Ouyang, Xinhui Su
Pages: 961-970
Published online on: 16 June 2016

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Article

Sustainable inflammation transforms hepatic cells by causing oxidative stress injury and potential epithelial-mesenchymal transition

Kun Lu, Guoyan Liu, Ling Yang, Fan Liu, Libin Gao, Jingxian Shi, Xiaoling Deng, Qifu Li, Donghui Xu, Songlin Shi
Pages: 971-980
Published online on: 16 June 2016

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Article

Lentivirus-mediated downregulation of MAT2B inhibits cell proliferation and induces apoptosis in melanoma

Yu Lei, Bo Zhang, Yaohua Zhang, Yuan Zhao, Jingying Sun, Xuejun Zhang, Sen Yang
Pages: 981-990
Published online on: 05 July 2016

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Article

Association between cancer stem cell-like properties and epithelial-to-mesenchymal transition in primary and secondary cancer cells

Wonbong Lim, Hye-Eun Kim, Young Kim, Risu Na, Xiaojie Li, Sangmi Jeon, Hongran Choi, Okjoon Kim
Pages: 991-1000
Published online on: 16 June 2016

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Article

SPOP promotes tumor progression via activation of β-catenin/TCF4 complex in clear cell renal cell carcinoma

Wencai Zhao, Jiancheng Zhou, Zhuo Deng, Yang Gao, Yongyi Cheng
Pages: 1001-1008
Published online on: 06 July 2016

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Article

Baicalein induces apoptosis via ROS-dependent activation of caspases in human bladder cancer 5637 cells

Eun-Ok Choi, Cheol Park, Hye-Jin Hwang, Su Hyun Hong, Gi-Young Kim, Eun-Ju Cho, Wun-Jae Kim, Yung Hyun Choi
Pages: 1009-1018
Published online on: 06 July 2016

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Article

Curcumin inhibits invasive capabilities through epithelial mesenchymal transition in breast cancer cell lines

Marcela Gallardo, Gloria M. Calaf
Pages: 1019-1027
Published online on: 04 July 2016

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Article

Silencing Aurora-A with siRNA inhibits cell proliferation in human lung adenocarcinoma cells

Ning Zhong, Shunbin Shi, Hongzhen Wang, Guangzhou Wu, Yunliang Wang, Qiang Ma, Hongwei Wang, Yuanhua Liu, Jinzhi Wang
Pages: 1028-1038
Published online on: 05 July 2016

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Article

The novel mTORC1/2 dual inhibitor INK128 enhances radiosensitivity of breast cancer cell line MCF-7

Zhi-Gang Liu, Jiao Tang, Zhenghu Chen, Huiyuan Zhang, Hui Wang, Jianhua Yang, Hong Zhang
Pages: 1039-1045
Published online on: 05 July 2016

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Article

TSC22D2 interacts with PKM2 and inhibits cell growth in colorectal cancer

Fang Liang, Qiao Li, Xiayu Li, Zheng Li, Zhaojian Gong, Hao Deng, Bo Xiang, Ming Zhou, Xiaoling Li, Guiyuan Li, Zhaoyang Zeng, Wei Xiong
Pages: 1046-1056
Published online on: 04 July 2016

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Article

Heterogeneous expression of zinc-finger E-box-binding homeobox 1 plays a pivotal role in metastasis via regulation of miR-200c in epithelial-mesenchymal transition

Yuta Muto, Koichi Suzuki, Takaharu Kato, Shingo Tsujinaka, Kosuke Ichida, Yuji Takayama, Taro Fukui, Nao Kakizawa, Fumiaki Watanabe, Masaaki Saito, Kazushige Futsuhara, Hiroshi Noda, Yasuyuki Miyakura, Fumio Konishi, Toshiki Rikiyama
Pages: 1057-1067
Published online on: 17 June 2016

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Article

MicroRNA-224 aggrevates tumor growth and progression by targeting mTOR in gastric cancer

Ying Zhang, Chang-Feng Li, Lian-Jun Ma, Meng Ding, Bin Zhang
Pages: 1068-1080
Published online on: 16 June 2016

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Article

A 3-dimensional DTI MRI-based model of GBM growth and response to radiation therapy

Leith Hathout, Vishal Patel, Patrick Wen
Pages: 1081-1087
Published online on: 01 July 2016

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Article

Torilis japonica extract-generated intracellular ROS induces apoptosis by reducing the mitochondrial membrane potential via regulation of the AMPK-p38 MAPK signaling pathway in HCT116 colon cancer

Guen Tae Kim, Se Hee Lee, Young Min Kim
Pages: 1088-1098
Published online on: 16 June 2016

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Article

Immunological effects of the anti-programmed death-1 antibody on human peripheral blood mononuclear cells

Yasuto Akiyama, Chizu Nonomura, Ryota Kondou, Haruo Miyata, Tadashi Ashizawa, Chie Maeda, Koichi Mitsuya, Nakamasa Hayashi, Yoko Nakasu, Ken Yamaguchi
Pages: 1099-1107
Published online on: 29 June 2016

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Article

Weighted gene co-expression network analysis of colorectal cancer liver metastasis genome sequencing data and screening of anti-metastasis drugs

Bo Gao, Qin Shao, Hani Choudhry, Victoria Marcus, Kung Dong, Jiannis Ragoussis, Zu-Hua Gao
Pages: 1108-1118
Published online on: 30 June 2016

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Article

The tumor-suppressive microRNA-23b/27b cluster regulates the MET oncogene in oral squamous cell carcinoma

Ichiro Fukumoto, Keiichi Koshizuka, Toyoyuki Hanazawa, Naoko Kikkawa, Ryosuke Matsushita, Akira Kurozumi, Mayuko Kato, Atsushi Okato, Yoshitaka Okamoto, Naohiko Seki
Pages: 1119-1129
Published online on: 04 July 2016

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Article

Anti-EGFR immunonanoparticles containing IL12 and salmosin genes for targeted cancer gene therapy

Jung Seok Kim, Seong Jae Kang, Hwa Yeon Jeong, Min Woo Kim, Sang Il Park, Yeon Kyung Lee, Hong Sung Kim, Keun Sik Kim, Yong Serk Park
Pages: 1130-1138
Published online on: 07 July 2016

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Article

The inhibition of cell proliferation and induction of apoptosis in pancreatic ductal adenocarcinoma cells by verrucarin A, a macrocyclic trichothecene, is associated with the inhibition of Akt/NF-кB/mTOR prosurvival signaling

Dorrah Deeb, Xiaohua Gao, Yongbo Liu, Yiguan Zhang, Jiajiu Shaw, Frederick A. Valeriote, Subhash C. Gautam
Pages: 1139-1147
Published online on: 29 June 2016

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Article

Eupatilin inhibits EGF-induced JB6 cell transformation by targeting PI3K

Feng Li, Ya Tao, Yan Qiao, Ke Li, Yanan Jiang, Chang Cao, Shuxin Ren, Xiaobin Chang, Xiaona Wang, Yanhong Wang, Yifei Xie, Ziming Dong, Jimin Zhao, Kangdong Liu
Pages: 1148-1154
Published online on: 04 July 2016

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Article

MicroRNA-195 targets VEGFR2 and has a tumor suppressive role in ACHN cells via PI3K/Akt and Raf/MEK/ERK signaling pathways Expression of Concern in /10.3892/ijo.2025.5792

Pengcheng Sun, Lu Wang, Yunhan Lu, Yuwei Liu, Lechen Li, Luyao Yin, Cheng Zhang, Weiming Zhao, Baozhong Shen, Wanhai Xu
Pages: 1155-1163
Published online on: 06 July 2016

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Article

Targeting the PI3K/AKT/mTOR pathway overcomes the stimulating effect of dabrafenib on the invasive behavior of melanoma cells with acquired resistance to the BRAF inhibitor

Simona Caporali, Ester Alvino, Pedro Miguel Lacal, Lauretta Levati, Giorgio Giurato, Domenico Memoli, Elisabetta Caprini, Gian Carlo Antonini Cappellini, Stefania D'Atri
Pages: 1164-1174
Published online on: 30 June 2016

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Article

FHIT promoter methylation status, low protein and high mRNA levels in patients with non-small cell lung cancer

Karolina H. Czarnecka, Monika Migdalska-Sęk, Daria Domańska, Dorota Pastuszak-Lewandoska, Agata Dutkowska, Jacek Kordiak, Ewa Nawrot, Justyna Kiszałkiewicz, Adam Antczak, Ewa Brzeziańska-Lasota
Pages: 1175-1184
Published online on: 06 July 2016

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Article

Influence of molecular design on biodistribution and targeting properties of an Affibody-fused HER2-recognising anticancer toxin

Mohamed Altai, Hao Liu, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund
Pages: 1185-1194
Published online on: 06 July 2016

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Article

Protein arginine methyltransferase 5 is associated with malignant phenotype and peritoneal metastasis in gastric cancer

Mitsuro Kanda, Dai Shimizu, Tsutomu Fujii, Haruyoshi Tanaka, Masahiro Shibata, Naoki Iwata, Masamichi Hayashi, Daisuke Kobayashi, Chie Tanaka, Suguru Yamada, Goro Nakayama, Hiroyuki Sugimoto, Masahiko Koike, Michitaka Fujiwara, Yasuhiro Kodera
Pages: 1195-1202
Published online on: 17 June 2016

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Article

Genistein targets the cancerous inhibitor of PP2A to induce growth inhibition and apoptosis in breast cancer cells

Qingxia Zhao, Ming Zhao, Amanda B. Parris, Ying Xing, Xiaohe Yang
Pages: 1203-1210
Published online on: 30 June 2016

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Article

Inhibition of pregnane X receptor pathway contributes to the cell growth inhibition and apoptosis of anticancer agents in ovarian cancer cells

Hisashi Masuyama, Keiichiro Nakamura, Etsuko Nobumoto, Yuji Hiramatsu
Pages: 1211-1220
Published online on: 06 July 2016

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Article

An azaspirane derivative suppresses growth and induces apoptosis of ER-positive and ER-negative breast cancer cells through the modulation of JAK2/STAT3 signaling pathway

Nurfarhanah Bte Syed Sulaiman, Chakrabhavi Dhananjaya Mohan, Salundi Basappa, Vijay Pandey, Shobith Rangappa, Hanumantharayappa Bharathkumar, Alan Prem Kumar, Peter E. Lobie, Kanchugarakoppal S. Rangappa
Pages: 1221-1229
Published online on: 06 July 2016

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Article

Suppression of MMP-9 and FAK expression by pomolic acid via blocking of NF-κB/ERK/mTOR signaling pathways in growth factor-stimulated human breast cancer cells

Ji-Hyun Park, Yoon Young Cho, Seong Woo Yoon, Byoungduck Park
Pages: 1230-1240
Published online on: 29 June 2016

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Article

5-Azacytidine regulates matrix metalloproteinase-9 expression, and the migration and invasion of human fibrosarcoma HT1080 cells via PI3-kinase and ERK1/2 pathways

Seon-Mi Yu, Song Ja Kim
Pages: 1241-1247
Published online on: 06 July 2016

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Article

Induction of TTF-1 or PAX-8 expression on proliferation and tumorigenicity in thyroid carcinomas

Célia Dupain, Hafiz M. Ali, Tarik Ait Mouhoub, Giorgia Urbinati, Liliane Massaad-Massade
Pages: 1248-1258
Published online on: 07 July 2016

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Correction Open Access

[Corrigendum] Preventive effect of caffeine and curcumin on hepato-carcinogenesis in diethylnitrosamine-induced rats

Yuki Fujise, Jun-Ichi Okano, Takakazu Nagahara, Ryo Abe, Ryu Imamoto, Yoshikazu Murawaki
Pages: 1259-1259
Published online on: 15 June 2016

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Correction Open Access

[Corrigendum] Cisplatin in combination with zoledronic acid: A synergistic effect in triple-negative breast cancer cell lines

Toni Ibrahim, Chiara Liverani, Laura Mercatali, Emanuele Sacanna, Michele Zanoni, Francesco Fabbri, Wainer Zoli, Dino Amadori
Pages: 1260-1260
Published online on: 06 July 2016

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Journal Cover
September-2026 Volume 69 Issue 3

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Cover Legend PDF

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Review Open Access

The role of deubiquitinating enzymes and their inhibitors in esophageal carcinoma (Review)

Yu Zhao, Chenghai He, Kexin Chen, Nanting Sun, Ruonan He, Guodong Li
Article Number: 108
Published online on: 16 July 2026

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Correction Open Access

[Corrigendum] AHIF promotes glioblastoma progression and radioresistance via exosomes

Xuejun Dai, Keman Liao, Zhijun Zhuang, Binghong Chen, Zhiyi Zhou, Sunhai Zhou, Guoshi Lin, Feifei Zhang, Yingying Lin, Yifeng Miao, Zhiqiang Li, Renhua Huang, Yongming Qiu, Ruisheng Lin
Article Number: 107
Published online on: 15 July 2026

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Article Open Access

Triptonide enhances DNA damage by inhibiting TRIP13‑mediated DNA repair and synergizes with bortezomib to suppress multiple myeloma

Fen He, Junjun Li, Lijun Peng, Hongyan Zhao, Maoyou Lu, Ruixin Gao, Siqi Wang, Yu Chen, Ruihan Tang, Zhengguo Li, Linlin Zhang, Xinyu Zhang, Qianhao Li, Weihui Chen, Jiayu Liu, Cong Luo, Xi Zeng, Jiliang Xia
Article Number: 106
Published online on: 14 July 2026

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Article Open Access

YAP1‑mediated cytoplasmic‑nuclear translocation of SREBP2 promotes colorectal cancer via regulation of cholesterol metabolism

Luhui Zhong, Min Sun, Di Wu, Yulan Zeng, Min Zhou, Rui Gong, Feifei Gu, Kai Zhang, Xiaoyan Hu, Yue Hu
Article Number: 105
Published online on: 13 July 2026

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Review Open Access

Immunoediting and precision biomarkers in prostate cancer: The emerging role of liquid biopsy, immune contexture and HLA genotype (Review)

Constantin N. Baxevanis, Savvas Stokidis, Sotirios P. Fortis, Maria Goulielmaki, Ourania E. Tsitsilonis, Angelos D. Gritzapis
Article Number: 104
Published online on: 13 July 2026

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Retraction Open Access

[Retracted] Phenotypic characterization of human prostatic stromal cells in primary cultures derived from human tissue samples

Giovanni Luca Gravina, Andrea Mancini, Guido Ranieri, Boris Di Pasquale, Francesco Marampon, Luigi Di Clemente, Enrico Ricevuto, Claudio Festuccia
Article Number: 103
Published online on: 13 July 2026

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Review Open Access

The neural stem cell‑NSCLC axis: Molecular drivers, microenvironment crosstalk and emerging therapies (Review)

Yanling Xu, Hanmei Duan, Peng Lu, Feng Liu
Article Number: 102
Published online on: 10 July 2026

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Review Open Access

TGF‑β1 in cancer: From tumour suppressor to promoter, molecular mechanisms, and precision therapeutic strategies (Review)

Chao Huang
Article Number: 101
Published online on: 10 July 2026

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Article Open Access

T‑box transcription factor 15 regulated by methyltransferase‑like 3‑mediated N6‑methyladenosine modification promotes immune escape and progression of gastric cancer by activating matrix metalloproteinase 14 transcription

Hongsai Hu, Rong He, Minji Liu, Xuli Liu, Qiongjia Ai, Min Chen, Qian Wang, Wenhui Chen, Weiming Qu
Article Number: 100
Published online on: 09 July 2026

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Review Open Access

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review)

Bo Zhang, Lihan Shang, Ziyu Kuang, Chaoran Wang, Bingsheng Sun, Fanming Kong
Article Number: 99
Published online on: 09 July 2026

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Review Open Access

New insights into the physiological, pathological and pharmacological roles of voltage‑gated potassium channel Kv10.1 in cancer (Review)

Yuxiao Zhen, Weibo Hu, Shanshan Dong, Bochang Wang, Jian Shen, Leyuan Ding, Lifeng Li, Hailong An, Xuzhao Wang, Yafei Chen
Article Number: 98
Published online on: 09 July 2026

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Retraction Open Access

[Retracted] Glycyrrhetinic acid induces G1‑phase cell cycle arrest in human non‑small cell lung cancer cells through endoplasmic reticulum stress pathway

Jie Zhu, Meijuan Chen, Ning Chen, Aizhen Ma, Chunyan Zhu, Ruolin Zhao, Miao Jiang, Jing Zhou, Lihong Ye, Haian Fu, Xu Zhang
Article Number: 97
Published online on: 06 July 2026

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October-2026 Volume 69 Issue 4

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Journal Metrics

Impact Factor: 7.3

CiteScore: 10.2

CiteScore Rank: Q1: #51/428 Oncology

Source Normalized Impact per Paper (SNIP): 0.955

SCImago Journal Rank (SJR): 1226.0

Correction Open Access

[Corrigendum] Influence of doxorubicin on apoptosis and oxidative stress in breast cancer cell lines

Nesstor Pilco‑Ferreto, Gloria   M. Calaf
Article Number: 110
Published online on: 20 July 2026

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Article Open Access

Evaluation of Punicalagin as a multi‑targeted therapeutic agent against endometrial cancer

Zeeshan Ahmad Bhutta, Dohee Ahn, Hong Kyu Lee, Kyung-Chul Choi
Article Number: 109
Published online on: 17 July 2026

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