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International Journal of Oncology
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Print ISSN: 1019-6439 Online ISSN: 1791-2423
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Review

MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review)

  • Authors:
    • Tianhe Huang
    • Feng Wang-Johanning
    • Fuling Zhou
    • Herbert Kallon
    • Yongchang Wei
  • View Affiliations / Copyright

    Affiliations: Department of Clinical Oncology, The First Affiliated Hospital, Medical School of Xi'an Jiaotong University Xi'an, Shaanxi 710061, P.R. China, Viral Oncology Program, SRI International, Menlo Park, CA, USA, Department of Clinical Hematology, The Second Affiliated Hospital, Medical School of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, P.R. China, College of Medicine, Xi'an Jiaotong University, Xi'an, Shaanxi 710061, P.R. China, Department of Radiation and Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, P.R. China
  • Pages: 1791-1800
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    Published online on: September 9, 2016
       https://doi.org/10.3892/ijo.2016.3686
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Abstract

Gastric cancer (GC) remains one of the most prevalent tumors worldwide and affects human health due to its high morbidity and mortality. Mechanisms underlying occurrence and development of GC have been widely studied. Studies have revealed reactive oxygen species (ROS) generated by cells under oxidative stress (OS) are involved in gastric tumorigenesis, and modulate expression of microRNAs (miRs). As such, miRs have been shown to be associated with OS-related GC. Given the association of OS and miRs in development of GC, this review aims to summarize the relationship between miRs and OS and their role in GC development. Serving as a link between OS and GC, miRs may offer new approaches for gaining a more in-depth understanding of mechanisms of GC and may lead to the identification of new therapeutic approaches against GC.
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Copy and paste a formatted citation
Spandidos Publications style
Huang T, Wang-Johanning F, Zhou F, Kallon H and Wei Y: MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review). Int J Oncol 49: 1791-1800, 2016.
APA
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., & Wei, Y. (2016). MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review). International Journal of Oncology, 49, 1791-1800. https://doi.org/10.3892/ijo.2016.3686
MLA
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., Wei, Y."MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review)". International Journal of Oncology 49.5 (2016): 1791-1800.
Chicago
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., Wei, Y."MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review)". International Journal of Oncology 49, no. 5 (2016): 1791-1800. https://doi.org/10.3892/ijo.2016.3686
Copy and paste a formatted citation
x
Spandidos Publications style
Huang T, Wang-Johanning F, Zhou F, Kallon H and Wei Y: MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review). Int J Oncol 49: 1791-1800, 2016.
APA
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., & Wei, Y. (2016). MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review). International Journal of Oncology, 49, 1791-1800. https://doi.org/10.3892/ijo.2016.3686
MLA
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., Wei, Y."MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review)". International Journal of Oncology 49.5 (2016): 1791-1800.
Chicago
Huang, T., Wang-Johanning, F., Zhou, F., Kallon, H., Wei, Y."MicroRNAs serve as a bridge between oxidative stress and gastric cancer (Review)". International Journal of Oncology 49, no. 5 (2016): 1791-1800. https://doi.org/10.3892/ijo.2016.3686
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