|
1
|
Jemal A, Bray F, Center MM, Ferlay J, Ward
E and Forman D: Global cancer statistics. CA Cancer J Clin.
61:69–90. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
2
|
Lok AS, Seeff LB, Morgan TR, di Bisceglie
AM, Sterling RK, Curto TM, Everson GT, Lindsay KL, Lee WM,
Bonkovsky HL, et al HALT-C Trial Group: Incidence of hepatocellular
carcinoma and associated risk factors in hepatitis C-related
advanced liver disease. Gastroenterology. 136:138–148. 2009.
View Article : Google Scholar
|
|
3
|
Yuen MF, Tanaka Y, Fong DY, Fung J, Wong
DK, Yuen JC, But DY, Chan AO, Wong BC, Mizokami M, et al:
Independent risk factors and predictive score for the development
of hepato-cellular carcinoma in chronic hepatitis B. J Hepatol.
50:80–88. 2009. View Article : Google Scholar
|
|
4
|
Diehl AM: Alcoholic liver disease: Natural
history. Liver Transpl Surg. 3:206–211. 1997.PubMed/NCBI
|
|
5
|
Tomimaru Y, Wada H, Eguchi H, Tomokuni A,
Hama N, Kawamoto K, Marubashi S, Umeshita K, Doki Y, Mori M, et al:
Clinical significance of surgical resection of metastatic lymph
nodes from hepatocellular carcinoma. Surg Today. 45:1112–1120.
2015. View Article : Google Scholar
|
|
6
|
Okamura Y, Ashida R, Ito T, Sugiura T,
Mori K and Uesaka K: The tumor marker score is an independent
predictor of survival in patients with recurrent hepatocellular
carcinoma. Surg Today. 45:1513–1520. 2015. View Article : Google Scholar
|
|
7
|
Wu TH, Hatano E, Yamanaka K, Seo S, Taura
K, Yasuchika K, Fujimoto Y, Nitta T, Mizumoto M, Mori A, et al: A
non-smooth tumor margin on preoperative imaging predicts
microvascular invasion of hepatocellular carcinoma. Surg Today.
46:1275–1281. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
8
|
Hao S, Fan P, Chen S, Tu C and Wan C:
Distinct recurrence risk factors for intrahepatic metastasis and
multicenter occurrence after surgery in patients with
hepatocellular carcinoma. J Gastrointest Surg. 21:312–320. 2016.
View Article : Google Scholar : PubMed/NCBI
|
|
9
|
Pastorekova S, Ratcliffe PJ and Pastorek
J: Molecular mechanisms of carbonic anhydrase IX-mediated pH
regulation under hypoxia. BJU Int. 101(Suppl 4): 8–15. 2008.
View Article : Google Scholar : PubMed/NCBI
|
|
10
|
Swietach P, Wigfield S, Cobden P, Supuran
CT, Harris AL and Vaughan-Jones RD: Tumor-associated carbonic
anhydrase 9 spatially coordinates intracellular pH in
three-dimensional multicellular growths. J Biol Chem.
283:20473–20483. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
11
|
Wykoff CC, Beasley NJ, Watson PH, Turner
KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell
PH, et al: Hypoxia-inducible expression of tumor-associated
carbonic anhydrases. Cancer Res. 60:7075–7083. 2000.
|
|
12
|
Swinson DE, Jones JL, Richardson D, Wykoff
C, Turley H, Pastorek J, Taub N, Harris AL and O'Byrne KJ: Carbonic
anhydrase IX expression, a novel surrogate marker of tumor hypoxia,
is associated with a poor prognosis in non-small-cell lung cancer.
J Clin Oncol. 21:473–482. 2003. View Article : Google Scholar : PubMed/NCBI
|
|
13
|
Giatromanolaki A, Koukourakis MI, Sivridis
E, Pastorek J, Wykoff CC, Gatter KC and Harris AL: Expression of
hypoxia-inducible carbonic anhydrase-9 relates to angiogenic
pathways and independently to poor outcome in non-small cell lung
cancer. Cancer Res. 61:7992–7998. 2001.PubMed/NCBI
|
|
14
|
Chia SK, Wykoff CC, Watson PH, Han C, Leek
RD, Pastorek J, Gatter KC, Ratcliffe P and Harris AL: Prognostic
significance of a novel hypoxia-regulated marker, carbonic
anhydrase IX, in invasive breast carcinoma. J Clin Oncol.
19:3660–3668. 2001. View Article : Google Scholar : PubMed/NCBI
|
|
15
|
Tan EY, Yan M, Campo L, Han C, Takano E,
Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, et al: The
key hypoxia regulated gene CAIX is upregulated in basal-like breast
tumours and is associated with resistance to chemotherapy. Br J
Cancer. 100:405–411. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
16
|
Kim HL, Seligson D, Liu X, Janzen N, Bui
MH, Yu H, Shi T, Figlin RA, Horvath S and Belldegrun AS: Using
protein expressions to predict survival in clear cell renal
carcinoma. Clin Cancer Res. 10:5464–5471. 2004. View Article : Google Scholar : PubMed/NCBI
|
|
17
|
Hoskin PJ, Sibtain A, Daley FM and Wilson
GD: GLUT1 and CAIX as intrinsic markers of hypoxia in bladder
cancer: Relationship with vascularity and proliferation as
predictors of outcome of ARCON. Br J Cancer. 89:1290–1297. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
18
|
Loncaster JA, Harris AL, Davidson SE,
Logue JP, Hunter RD, Wycoff CC, Pastorek J, Ratcliffe PJ, Stratford
IJ and West CM: Carbonic anhydrase (CA IX) expression, a potential
new intrinsic marker of hypoxia: Correlations with tumor oxygen
measurements and prognosis in locally advanced carcinoma of the
cervix. Cancer Res. 61:6394–6399. 2001.PubMed/NCBI
|
|
19
|
Thiery JP, Acloque H, Huang RY and Nieto
MA: Epithelial-mesenchymal transitions in development and disease.
Cell. 139:871–890. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
20
|
Tsai YP and Wu KJ: Hypoxia-regulated
target genes implicated in tumor metastasis. J Biomed Sci.
19:1022012. View Article : Google Scholar : PubMed/NCBI
|
|
21
|
Wu X, Qiao B, Liu Q and Zhang W:
Upregulation of extracellular matrix metalloproteinase inducer
promotes hypoxia-induced epithelial-mesenchymal transition in
esophageal cancer. Mol Med Rep. 12:7419–7424. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
22
|
Tang J, Xiao L, Cui R, Li D, Zheng X, Zhu
L, Sun H, Pan Y, Du Y and Yu X: CX3CL1 increases invasiveness and
metastasis by promoting epithelial-to-mesenchymal transition
through the TACE/TGF-α/EGFR pathway in hypoxic androgen-independent
prostate cancer cells. Oncol Rep. 35:1153–1162. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
23
|
Svastová E, Zilka N, Zat'ovicová M,
Gibadulinová A, Ciampor F, Pastorek J and Pastoreková S: Carbonic
anhydrase IX reduces E-cadherin-mediated adhesion of MDCK cells via
interaction with beta-catenin. Exp Cell Res. 290:332–345. 2003.
View Article : Google Scholar : PubMed/NCBI
|
|
24
|
Noda T, Yamamoto H, Takemasa I, Yamada D,
Uemura M, Wada H, Kobayashi S, Marubashi S, Eguchi H, Tanemura M,
et al: PLOD2 induced under hypoxia is a novel prognostic factor for
hepatocellular carcinoma after curative resection. Liver Int.
32:110–118. 2012. View Article : Google Scholar
|
|
25
|
Sakamoto T, Kobayashi S, Yamada D, Nagano
H, Tomokuni A, Tomimaru Y, Noda T, Gotoh K, Asaoka T, Wada H, et
al: A histone deacetylase inhibitor suppresses
epithelial-mesenchymal transition and attenuates chemoresistance in
biliary tract cancer. PLoS One. 11:e01459852016. View Article : Google Scholar : PubMed/NCBI
|
|
26
|
Wang GL, Jiang BH, Rue EA and Semenza GL:
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS
heterodimer regulated by cellular O2 tension. Proc Natl
Acad Sci USA. 92:5510–5514. 1995. View Article : Google Scholar
|
|
27
|
Amann T and Hellerbrand C: GLUT1 as a
therapeutic target in hepatocellular carcinoma. Expert Opin Ther
Targets. 13:1411–1427. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
28
|
Kim KR, Moon HE and Kim KW:
Hypoxia-induced angiogenesis in human hepatocellular carcinoma. J
Mol Med (Berl). 80:703–714. 2002. View Article : Google Scholar
|
|
29
|
Pastorek J and Pastorekova S:
Hypoxia-induced carbonic anhydrase IX as a target for cancer
therapy: From biology to clinical use. Semin Cancer Biol. 31:52–64.
2015. View Article : Google Scholar
|
|
30
|
Griguer CE, Oliva CR, Kelley EE, Giles GI,
Lancaster JR Jr and Gillespie GY: Xanthine oxidase-dependent
regulation of hypoxia-inducible factor in cancer cells. Cancer Res.
66:2257–2263. 2006. View Article : Google Scholar : PubMed/NCBI
|
|
31
|
Choi JH, Cho HK, Choi YH and Cheong J:
Activating transcription factor 2 increases transactivation and
protein stability of hypoxia-inducible factor 1alpha in
hepatocytes. Biochem J. 424:285–296. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
32
|
Rankin EB and Giaccia AJ: Hypoxic control
of metastasis. Science. 352:175–180. 2016. View Article : Google Scholar : PubMed/NCBI
|
|
33
|
Balamurugan K: HIF-1 at the crossroads of
hypoxia, inflammation, and cancer. Int J Cancer. 138:1058–1066.
2016. View Article : Google Scholar
|
|
34
|
Zhang L, Huang G, Li X, Zhang Y, Jiang Y,
Shen J, Liu J, Wang Q, Zhu J, Feng X, et al: Hypoxia induces
epithelial-mesenchymal transition via activation of SNAI1 by
hypoxia-inducible factor -1α in hepatocellular carcinoma. BMC
Cancer. 13:1082013. View Article : Google Scholar
|
|
35
|
Yang YJ, Na HJ, Suh MJ, Ban MJ, Byeon HK,
Kim WS, Kim JW, Choi EC, Kwon HJ, Chang JW, et al: Hypoxia induces
epithelial-mesenchymal transition in follicular thyroid cancer:
Involvement of regulation of twist by hypoxia inducible factor-1α.
Yonsei Med J. 56:1503–1514. 2015. View Article : Google Scholar : PubMed/NCBI
|
|
36
|
Matsuoka J, Yashiro M, Doi Y, Fuyuhiro Y,
Kato Y, Shinto O, Noda S, Kashiwagi S, Aomatsu N, Hirakawa T, et
al: Hypoxia stimulates the EMT of gastric cancer cells through
autocrine TGFβ signaling. PLoS One. 8:e623102013. View Article : Google Scholar
|
|
37
|
Chiche J, Ilc K, Laferrière J, Trottier E,
Dayan F, Mazure NM, Brahimi-Horn MC and Pouysségur J:
Hypoxia-inducible carbonic anhydrase IX and XII promote tumor cell
growth by counteracting acidosis through the regulation of the
intracellular pH. Cancer Res. 69:358–368. 2009. View Article : Google Scholar : PubMed/NCBI
|
|
38
|
Yu SJ, Yoon JH, Lee JH, Myung SJ, Jang ES,
Kwak MS, Cho EJ, Jang JJ, Kim YJ and Lee HS: Inhibition of
hypoxia-inducible carbonic anhydrase-IX enhances hexokinase II
inhibitor-induced hepatocellular carcinoma cell apoptosis. Acta
Pharmacol Sin. 32:912–920. 2011. View Article : Google Scholar : PubMed/NCBI
|
|
39
|
Lock FE, McDonald PC, Lou Y, Serrano I,
Chafe SC, Ostlund C, Aparicio S, Winum JY, Supuran CT and Dedhar S:
Targeting carbonic anhydrase IX depletes breast cancer stem cells
within the hypoxic niche. Oncogene. 32:5210–5219. 2013. View Article : Google Scholar
|
|
40
|
Cavey M, Rauzi M, Lenne PF and Lecuit T: A
two-tiered mechanism for stabilization and immobilization of
E-cadherin. Nature. 453:751–756. 2008. View Article : Google Scholar : PubMed/NCBI
|
|
41
|
Nieto MA: The snail superfamily of
zinc-finger transcription factors. Nat Rev Mol Cell Biol.
3:155–166. 2002. View
Article : Google Scholar : PubMed/NCBI
|
|
42
|
Kalluri R and Weinberg RA: The basics of
epithelial-mesen-chymal transition. J Clin Invest. 119:1420–1428.
2009. View Article : Google Scholar : PubMed/NCBI
|
|
43
|
Chou YS and Yang MH:
Epithelial-mesenchymal transition-related factors in solid tumor
and hematological malignancy. J Chin Med Assoc. 78:438–445. 2015.
View Article : Google Scholar : PubMed/NCBI
|
|
44
|
Baulida J and García de Herreros A:
Snail1-driven plasticity of epithelial and mesenchymal cells
sustains cancer malignancy. Biochim Biophys Acta. 1856:55–61.
2015.PubMed/NCBI
|
|
45
|
Luong-Player A, Liu H, Wang HL and Lin F:
Immunohistochemical reevaluation of carbonic anhydrase IX (CA IX)
expression in tumors and normal tissues. Am J Clin Pathol.
141:219–225. 2014. View Article : Google Scholar : PubMed/NCBI
|
|
46
|
Kang HJ, Kim IH, Sung CO, Shim JH and Yu
E: Expression of carbonic anhydrase 9 is a novel prognostic marker
in resectable hepatocellular carcinoma. Virchows Arch. 466:403–413.
2015. View Article : Google Scholar : PubMed/NCBI
|
|
47
|
Huang WJ, Jeng YM, Lai HS, Fong IU, Sheu
FY, Lai PL and Yuan RH: Expression of hypoxic marker carbonic
anhydrase IX predicts poor prognosis in resectable hepatocellular
carcinoma. PLoS One. 10:e01191812015. View Article : Google Scholar : PubMed/NCBI
|
